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Montone Rocco A - - 2014
To the Editor: The negative results of the ATLANTIC (Administration of Ticagrelor in the Cath Lab or in the Ambulance for New ST Elevation Myocardial Infarction to Open the Coronary Artery) trial reported by Montalescot et al. (Sept. 11 issue)(1) are not unexpected, since previous pharmacodynamic studies(2),(3) have shown that ...
Toggweiler Stefan - - 2014
To the Editor: The negative results of the ATLANTIC (Administration of Ticagrelor in the Cath Lab or in the Ambulance for New ST Elevation Myocardial Infarction to Open the Coronary Artery) trial reported by Montalescot et al. (Sept. 11 issue)(1) are not unexpected, since previous pharmacodynamic studies(2),(3) have shown that ...
Parodi Guido - - 2014
To the Editor: The negative results of the ATLANTIC (Administration of Ticagrelor in the Cath Lab or in the Ambulance for New ST Elevation Myocardial Infarction to Open the Coronary Artery) trial reported by Montalescot et al. (Sept. 11 issue)(1) are not unexpected, since previous pharmacodynamic studies(2),(3) have shown that ...
- - 2014
To the Editor: The negative results of the ATLANTIC (Administration of Ticagrelor in the Cath Lab or in the Ambulance for New ST Elevation Myocardial Infarction to Open the Coronary Artery) trial reported by Montalescot et al. (Sept. 11 issue)(1) are not unexpected, since previous pharmacodynamic studies(2),(3) have shown that ...
Barsukevich Veronika V Research Centre Cardiology, Minsk, - - 2015
Cardioprotection against ischaemia/reperfusion injury in mice can be achieved by delayed ischaemic postconditioning (IPost) applied as late as 30 min after the onset of reperfusion. We determined the efficacy of delayed IPost in a rat model of myocardial infarction (MI) and investigated potential underlying mechanisms of this phenomenon. Rats were subjected ...
Agha Hala Mounir HM Pediatric Department, Pediatric Cardiology Unit, Cairo University Children Hospital, Cairo, Egypt, - - 2014
Early heart iron overload in beta thalassemia major patients can be quantified through T2* cardiovascular magnetic resonance (CMR). To clarify the value of tissue Doppler imaging (TDI) in early detection of myocardial dysfunction in iron loaded thalassemia patients diagnosed by CMR. Two groups were included in the study; Group I: ...
Laine Marc M Service de Cardiologie, Centre Hospitalo-Universitaire Nord, Assistance-Publique Hôpitaux de Marseille , Chemin des Bourrely, Marseille , France - - 2014
Abstract Prasugrel and ticagrelor are potent P2Y12-ADP receptor antagonists which are superior to clopidogrel in acute coronary syndromes. To date no clinical trial directly compared these two drugs. Platelet reactivity correlates with ischemic and bleeding events in patients undergoing percutaneous coronary intervention. Recent pharmacological studies have observed a delayed onset ...
Peyrou Jérôme J Echocardiography laboratory, clinique Saint-Augustin, 114, avenue d'Arès, 33000 Bordeaux, - - 2014
According to recent USA guidelines, right ventricular (RV) dysfunction can be diagnosed on the basis of a single parameter, such as tricuspid lateral annular systolic velocity (S')<10cm/s or RV fractional area change (RVFAC)<35%. To assess these recommendations in a large unselected cohort of patients awaiting cardiac surgery and evaluate less ...
Jang Donghwan D Department of Neurosurgery, Kangwon National University Hospital, Chuncheon, - - 2014
Vertebral artery (VA) injuries usually accompany cervical trauma. Although these injuries are commonly asymptomatic, some result in vertebrobasilar infarction. The symptoms of VA occlusion have been reported to usually manifest within 24 hours after trauma. The symptoms of bilateral VA occlusions seem to be more severe and seem to occur ...
Jichun L - - 2014
We report a rare case of marked myocardial lipoma of the left ventricle free wall investigated with echocardiography, CT and comprehensive MRI. The case is a 52-year-old man with a history of arrhythmia, hypertension and palpitations. Echocardiography was normal except for the base of the interventricular septum which was slightly ...
Khalili Ahmadali A Department of Cardiac Surgery, Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, - - 2013
Cardiac lipomas are rarely encountered. They are mostly asymptomatic and may be discovered incidentally. We describe the case of a 56 year-old man with a presentation similar to tamponade. He had decreased heart sounds, global cardiomegaly, and oligemic lung fields. Echocardiography showed a 110 × 75-mm mass attached to the interatrial septum, ...
Censi Stefano - - 2013
A young man presented with recurrent ischemic stroke under antiplatelet therapy. A patent foramen ovale (PFO) was diagnosed by transesophageal echocardiography (TEE) and the patient was referred to our institution for percutaneous closure. An echogenic mass in the right atrium was detected during the intraprocedural TEE. The interventional team decided ...
Taguchi Shinichi - - 2013
A 35-year-old female presented with nonsustained ventricular tachycardia (NSVT) and a large intrapericardial mass. The mass was attached to the left ventricular wall with a broad stalk. On histopathology, the tumor was diagnosed as a lipoma. Postoperatively, the NSVT disappeared.
Müller Alison L - - 2012
It has become evident that protein degradation by proteolytic enzymes, known as proteases, is partly responsible for cardiovascular dysfunction in various types of heart disease. Both extracellular and intracellular alterations in proteolytic activities are invariably seen in heart failure associated with hypertrophic cardiomyopathy, dilated cardiomyopathy, hypertensive cardiomyopathy, diabetic cardiomyopathy, and ...
Wang Wenru - - 2012
Background: Healthcare providers are called on to assess and improve the health-related quality of life (HRQL) of patients with myocardial infarction (MI). However, there is lack of empirical data on HRQL of such individuals in mainland China. The purpose of this study is to assess HRQL and identify associated factors ...
Su Wenting - - 2012
OBJECTIVE: To evaluate the effect of serum albumin on prognosis and the power of albumin adding information to NT-proBNP in a Chinese cohort of heart failure. DESIGN AND METHODS: 385 consecutive patients (male vs. female: 292 vs. 93; mean age: 54.89±14.41years; NYHA classes II-V) admitted for heart failure exacerbation with ...
Quan Xin - - 2012
Mechanical asynchrony is an important parameter in predicting the response to cardiac resynchronization therapy, but detailed knowledge about cardiac timing in healthy persons is scarce. Therefore, in the current study, we sought to investigate the physiological status of interventricular synchronicity using pulse wave flow and tissue Doppler imaging in a ...
Zheng Guo-Hua - - 2012
Percutaneous coronary intervention (PCI) with stent placement is a standard treatment for coronary artery disease (CAD). In-stent restenosis after PCI remains a challenging clinical problem. In China, Chinese herbal medicines (CHMs) are widely used for preventing restenosis. This paper systematically reviewed the literature on the effectiveness and safety of CHMs ...
Luo Jing - - 2012
Objective. The aim of this overview was to summarize the outcome measures of Chinese herbal medicine (CHM) as the treatment of coronary heart disease (CHD) based on available systematic reviews (SRs), so as to display the current situation and evaluate the potential benefits and advantages of CHM on CHD. Methods. ...
Watson Roger - - 2012
Hierarchical scales are very useful in clinical practice due to their ability to discriminate precisely between individuals, and the original English version of the Myocardial Infarction Dimensional Assessment Scale has been shown to contain a hierarchy of items. The purpose of this study was to analyse a Mandarin Chinese translation ...
Hampton Thomas G - - 2012
Aberrant autonomic signaling is being increasingly recognized as an important symptom in neuromuscular disorders. The δ-sarcoglycan-deficient BIO TO-2 hamster is recognized as a good model for studying mechanistic pathways and sequelae in muscular dystrophy and heart failure, including autonomic nervous system (ANS) dysfunction. Recent studies using the TO-2 hamster model ...
Ahmed Amany - - 2011
A declining amplitude of body temperature circadian rhythm (BTCR) predicts decompensation or death in cardiomyopathic hamsters. We tested the hypothesis that changes in BTCR amplitude accompany significant changes in left ventricular (LV) size and function. Using intraperitoneal transmitters, we continuously monitored the temperature of 30 male BIO TO-2 Syrian dilated ...
Wang Wenru - - 2011
OBJECTIVE: This study evaluated the effects of a home-based rehabilitation program for Chinese patients with myocardial infarction in terms of health-related quality of life and psychological status. METHODS: This was a randomized, controlled trial with data collected at 2 university-affiliated public general hospitals in Xian (Shaanxi Province, People's Republic of ...
Yu M - - 2011
Chinese sirolimus-eluting stents (SES) have been widely used in recent years. However, the comparison of clinical outcomes between Chinese and foreign SES remains unknown. To compare the outcomes of Chinese SES (Firebird) with foreign SES (Cypher Select) in the treatment of patients undergoing percutaneous coronary intervention (PCI). 4000 consecutive patients ...
Levy Bruno - - 2011
: There is no study that has compared, in a randomized manner, which vasopressor is most suitable in optimizing both systemic and regional hemodynamics in cardiogenic shock patients. Hence, the present study was designed to compare epinephrine and norepinephrine-dobutamine in dopamine-resistant cardiogenic shock. : Open, randomized interventional human study. : ...
Dona Manjola - - 2011
The prognostic meaning of a post-stress ejection fraction (EF) decrease detected by perfusion gated SPECT is still unclear.We therefore followed up patients with post-stress EF decrease in the absence of stress-induced perfusion abnormalities. We prospectively enrolled 57 consecutive patients with post-stress EF drop ≥ 5 EF units and summed difference ...
Schinkel Arend F L - - 2010
Patients with chronic ischemic left ventricular dysfunction may have a substantial amount of viable, hibernating myocardium, which is a state of chronic contractile dysfunction with reduced blood flow at rest. Coronary revascularization in these patients may result in improvement of left ventricular function; in the absence of viability, left ventricular ...
Ge Wei W Department of Geriatrics, Fourth Military Medical University, Xi'an, - - 2010
Paraquat, a quaternary nitrogen herbicide, is a highly toxic pro-oxidant that causes multiorgan failure including that of the heart via generation of reactive oxygen species, although the underlying mechanism has not been well elucidated. This study examined the influence of cardiac-specific overexpression of catalase, an antioxidant detoxifying H(2)O(2), on paraquat-induced ...
Jhawar Manish B - - 2011
Left ventricular (LV) outflow tract obstruction (LVOTO) occurs in up to 20% of patients undergoing dobutamine stress echocardiography (DSE). Mid-cavity LV obstruction occurs less commonly during DSE. LV regional wall motion abnormalities during DSE may occur despite normal coronaries due to hypertensive blood pressure response and takotsubo stress cardiomyopathy. We ...
Odagiri Keiichi - - 2010
Transient ischemic dilatation (TID) and post-stress dysfunction of the left ventricle (LV) are important markers of severe coronary artery disease (CAD). To clarify the effects of stressor type on TID and post-stress LV dysfunction, changes in LV measurements were compared between patients with exercise- or vasodilator-induced stress. The 689 patients ...
Patrick David M DM Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9148, - - 2010
MicroRNAs inhibit mRNA translation or promote mRNA degradation by binding complementary sequences in 3' untranslated regions of target mRNAs. MicroRNA-21 (miR-21) is upregulated in response to cardiac stress, and its inhibition by a cholesterol-modified antagomir has been reported to prevent cardiac hypertrophy and fibrosis in rodents in response to pressure ...
Korosoglou Grigorios - - 2010
This study sought to determine the prognostic value of wall motion and perfusion assessment during high-dose dobutamine stress (DS) cardiac magnetic resonance imaging (MRI) in a large patient cohort. DS-MRI offers the possibility to integrate myocardial perfusion and wall motion analysis in a single examination for the detection of coronary ...
Zhang Min M Cardiovascular Division, King's College London British Heart Foundation Centre, London SE5 9PJ, United Kingdom. - - 2010
Cardiac failure occurs when the heart fails to adapt to chronic stresses. Reactive oxygen species (ROS)-dependent signaling is implicated in cardiac stress responses, but the role of different ROS sources remains unclear. Here we report that NADPH oxidase-4 (Nox4) facilitates cardiac adaptation to chronic stress. Unlike other Nox proteins, Nox4 ...
Rahman Fatima - - 2010
To investigate the usefulness of stress testing before discharge in patients assessed low to intermediate risk of acute coronary syndrome (ACS). A prospective observational study was undertaken of patients presenting to the ED with suspected myocardial ischaemia. After negative initial electrocardiogram (ECG) and serum troponin testing, patients were admitted to ...
Butman Samuel M - - 2010
Stress cardiomyopathy is described as acute myocardial infarction provoked by a stressful event with evidence of a significant focal wall motion but with little or no significant coronary artery disease. In this case report, a particularly bad bout of coughing resulted in chest pressure, troponin release, and evidence of antero-apical ...
Iwakura Katsuomi - - 2010
Low-dose dobutamine stress echocardiography (DSE) assesses myocardial viability at the early stage of acute myocardial infarction (AMI), but its assessment is subjective and variable. Automated function image (AFI) determines global longitudinal peak strain (GLPS) based on tissue tracking technique. The ability of GLPS obtained by AFI during dobutamine stress to ...
Yao Siu-Sun - - 2010
Stress echocardiography is an established technique for diagnosis, risk stratification, and prognosis in patients with known or suspected coronary artery disease. The ability of stress echocardiography to predict clinical outcomes, such as coronary angiography and revascularization, has not been reported previously. The purpose of this study was to evaluate the ...
Chelliah Rajesh - - 2010
Recent data have shown that exercise electrocardiogram (ECG) has no incremental prognostic value over clinical and rest ECG parameters in chest pain patients without a history of coronary artery disease (CAD). The incremental prognostic value of stress echocardiography (SE) in this population is unknown. Accordingly, 547 consecutive patients (68 ± ...
Ko Sung Min - - 2011
To evaluate the feasibility and diagnostic accuracy of adenosine-stress dual-energy computed tomography (DECT) for detecting haemodynamically significant stenosis causing reversible myocardial perfusion defect (PD) compared with stress perfusion magnetic resonance imaging (SP-MRI) and conventional coronary angiography (CCA). Fifty patients with known coronary artery disease (CAD) detected by dual-source CT (DSCT) ...
Yildirim Ayse - - 2010
Asymptomatic long-term cancer survivors treated with anthracycline were investigated for late anthracycline cardiotoxicity using dobutamine stress echocardiography (DSE) and tissue Doppler (TD) velocities. The study comprised 20 asymptomatic patient and 18 healthy children as the control group. Twenty patients were divided into two groups according to the myocardial wall motion ...
Mahajan N - - 2010
OBJECTIVES: Compare the diagnostic performance of stress echocardiography (SE) and myocardial perfusion imaging (MPI) for the diagnosis of left main disease (LM) and triple vessel disease (TVD). BACKGROUND: Limited comparative data on MPI and SE for the detection of LM and TVD (high-risk coronary artery disease) exist in the literature. ...
Williams Sarah E - - 2010
The present study investigated whether imagery could manipulate athletes' appraisal of stress-evoking situations (i.e., challenge or threat) and whether psychological and cardiovascular responses and interpretations varied according to cognitive appraisal of three imagery scripts: challenge, neutral, and threat. Twenty athletes (M(age) = 20.85; SD = 1.76; 10 female, 10 male) ...
Yao Siu-Sun - - 2010
The use of stress echocardiography has undergone considerable evolution in the past 3 decades. Although stress echocardiography was first introduced as a noninvasive diagnostic tool for determining the presence or absence of coronary artery disease (CAD), it later served a prognostic role as well. The importance of stress echocardiography in ...
Li Janette W - - 2010
A 67-year-old Caucasian woman presented with chest pain suggestive of acute pericarditis. On initial evaluation the apical ballooning variant of stress-related cardiomyopathy (CMP) was present. The stress CMP and acute pericarditis resolved within a week. The patient returned in four weeks with early cardiac tamponade, which required a pericardial window. ...
Badano Luigi P - - 2010
BACKGROUND: Compared with previous three-dimensional (3D) echocardiographic scanners, high-volume rate scanners allow higher temporal resolution and the possibility of displaying cropped images side by side. These new features make 3D echocardiography (3DE) even more attractive for application during stress. The aim of this study was to compare the feasibility and ...
Duvall W Lane - - 2010
BACKGROUND: Stress-only imaging saves time and radiation exposure, but apprehension remains about the reliability, diagnostic, and prognostic accuracy of a normal stress-only study. The objective of this study was to determine the prognosis of stress-only SPECT MPI in routine clinical practice. METHODS: Patients at lower pre-test risk for CAD presenting ...
Lee Jun-Won - - 2010
Stress-induced cardiomyopathy (SCM) is characterized by a transient left ventricular (LV) dysfunction due to emotional and physical stress. There are limited data about the clinical characteristics in Korean patients. We sought to clarify the clinical features and prognosis in patients with SCM. We reviewed 39 cases diagnosed with SCM in ...
Hickman Michael - - 2010
Controversy exists regarding the relative status of resting myocardial blood flow (MBF), coronary flow reserve (CFR), and contractile reserve (CR) in hibernating myocardium (HM). We hypothesized that CFR is more profoundly affected than resting MBF parameters in HM. Thus, resting MBF assessed by myocardial contrast echocardiography (MCE) will be more ...
Charoenpanichkit Charaslak C Departments of Internal Medicine Cardiology Section, Public Health Sciences, Biomedical Engineering, and Radiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1045, - - 2010
This study was performed to determine the utility of dobutamine stress test results for predicting myocardial infarction (MI) and cardiac death in patients with chest pain and left ventricular hypertrophy (LVH). Three hundred fifty-three participants with a mean+/-SD age of 64+/-12 years (54%men) underwent dobutamine cardiovascular magnetic resonance stress testing ...
Siebelink Hans-Marc J - - 2010
Detection of myocardial viability is an important issue that needs to be addressed when patients with dysfunctional myocardium are considered to be revascularised. The pathophysiological substrate may include myocardial hibernation, myocardial stunning, or both. The greatest benefit is in terms of myocardial function recovery and prognosis is obtained if the ...
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