Search Results
Results 201 - 250 of 1386
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Kowatsch Ingrid - - 2007
We sought to determine the value of dobutamine versus adenosine real-time myocardial perfusion (MP) echocardiography for detecting coronary artery disease and the value of quantitative analysis of MP over electrocardiography, wall motion, and qualitative MP. We studied 54 patients by real-time MP echocardiography and coronary angiography. Replenishment velocity (beta) and ...
Karagiannis Stefanos E - - 2007
Dobutamine stress echocardiography is a commonly used imaging modality for the diagnosis of coronary artery disease and the detection of myocardial viability. The major limitations are that it is operator dependent and that the analysis is subjective and qualitative resulting in interobserver variability. It is also tedious and time consuming. ...
Karagiannis Stefanos E - - 2007
OBJECTIVE: To assess the prognostic value of wall motion abnormalities during the recovery phase of dobutamine stress echocardiography in addition to wall motion abnormalities at peak stress. METHODS: Wall motion abnormalities were assessed at peak and during recovery phase of dobutamine stress echocardiography in 187 consecutive patients, who were followed ...
Alcendor Ralph R RR Cardiovascular Research Institute, Department of Cell Biology and Molecular Medicine, University of Medicine & Dentistry of New Jersey, New Jersey Medical School, Newark, NJ 07103, - - 2007
Silent information regulator (Sir)2, a class III histone deacetylase, mediates lifespan extension in model organisms and prevents apoptosis in mammalian cells. However, beneficial functions of Sir2 remain to be shown in mammals in vivo at the organ level, such as in the heart. We addressed this issue by using transgenic ...
Mahenthiran Jo - - 2007
BACKGROUND: Fragmented QRS (FQRS) complexes, not typical of a bundle branch block, are a marker of regional myocardial injury. The extent of stress myocardial perfusion imaging (MPI) abnormalities with FQRS patterns is not known. METHODS AND RESULTS: Twelve-lead electrocardiograms (ECGs) in 501 patients undergoing stress MPI were studied. FQRS was ...
Cortigiani Lauro - - 2007
This study investigated the value of pharmacologic stress echocardiography for risk stratification of patients > or =65 years of age. The study cohort consisted of 2,160 patients > or =65 years of age (1,257 men, mean +/- SD 71 +/- 5 years of age) undergoing dipyridamole (n = 1,521) or ...
Gray Marcus A - - 2007
Emotional trauma and psychological stress can precipitate cardiac arrhythmia and sudden death through arrhythmogenic effects of efferent sympathetic drive. Patients with preexisting heart disease are particularly at risk. Moreover, generation of proarrhythmic activity patterns within cerebral autonomic centers may be amplified by afferent feedback from a dysfunctional myocardium. An electrocortical ...
Ingul Charlotte Bjork - - 2007
OBJECTIVES: We investigated the accuracy of automated analysis of myocardial deformation during dobutamine stress echocardiography (DSE). BACKGROUND: The time required for segmental measurement of strain rate imaging (SRI) limits its feasibility for quantification of DSE. METHODS: Myocardial deformation was assessed at DSE in 197 patients, 76 with and 61 without ...
Cavusoglu Yuksel - - 2007
Levosimendan is a new calcium sensitizer with inotropic and vasodilatory actions mediated by the sensitization of contractile proteins to calcium, opening of potassium channels and inhibition of phosphodiesterase-3. Its alternative mechanisms of action to those of other traditional inotropes provide a new approach in the management of decompensated heart failure. ...
Gorenberg Miguel - - 2007
BACKGROUND: Electrocardiography has a very low sensitivity in detecting dobutamine-induced myocardial ischemia. OBJECTIVES: To assess the added diagnostic value of a new cardiac performance index (dP/dtejc) measurement, based on brachial artery flow changes, as compared to standard 12-lead ECG, for detecting dobutamine-induced myocardial ischemia, using Tc99m-Sestamibi single-photon emission computed tomography ...
Hori Yasutomo - - 2007
OBJECTIVE: To investigate the relationship between myocardial performance index (MPI; also known as the Tei index) and cardiac function in anesthetized cats administered dobutamine. ANIMALS: 6 adult cats. PROCEDURES: Cats were anesthetized by administration of propofol (6 mg/kg, IV), and anesthesia was maintained by administration of isoflurane. Heart rate and ...
Sasaki Hideki - - 2007
OBJECTIVES: Stress thallium-201 (201Tl) myocardial scintigraphy can demonstrate perfusion abnormalities, especially in the septum in patients with complete left bundle branch block (CLBBB) even with angiographically normal coronary arteries. Differences in the images between exercise and pharmacological stress 201Tl myocardial scintigraphy were evaluated in patients with CLBBB and normal coronary ...
De Hert Stefan G - - 2007
BACKGROUND: Patients with poor left ventricular function often require inotropic drug support immediately after cardiopulmonary bypass. Levosimendan improves cardiac function by a novel mechanism of action compared to currently available drugs. We hypothesized that, in patients with severely compromised ventricular function, the use of levosimendan would be associated with better ...
Yao Siu-Sun - - 2007
BACKGROUND: Transient ischemic dilation (TID) of the left ventricle on stress-redistribution thallium-201 scintigraphy is a marker of severe and extensive coronary artery disease (CAD), and associated with an adverse outcome. The significance of transient ischemic dilation during stress echocardiography is not well defined. METHODS: We assessed 155 patients undergoing stress ...
Nobrega Antonio C L - - 2008
Mental stress causes physiological autonomic adjustments that may trigger myocardial ischemia and ventricular dysfunction in patients with coronary artery disease. Thus, it was hypothetized that cholinergic stimulation may counteract the ventricular dysfunction provoked by mental stress in coronary disease. Six patients with coronary disease underwent a randomized, double-blind, cross-over, and ...
Kumar Ashwani - - 2008
The transient left ventricular apical ballooning is characterized by wall motion abnormalities involving the apex in the absence of obstructive coronary disease. It is precipitated by acute emotional or physical stress and is most often reported in post-menopausal women. We report a case of transient left ventricular "apical ballooning" without ...
Sozzi Fabiola B - - 2007
The prognostic significance of myocardial ischemia assessed by dobutamine stress echocardiography in asymptomatic patients with diabetes mellitus who have no previous coronary artery disease remains unclear. We assessed the value of dobutamine stress echocardiography for risk stratification in 161 asymptomatic patients with type 2 diabetes (mean 62 +/- 12 years ...
Heyne J P - - 2007
OBJECTIVE: To evaluate the impact on cardiac magnetic resonance imaging (CMRI) with adenosine stress and delayed enhancement for indication and follow up after interventional recanalisation of chronic total coronary occlusions (CTOs). MATERIAL AND METHODS: Twenty consecutive patients (15 males; 5 females; mean age 65 years) with CTO verified by cardiac ...
Bangalore Sripal - - 2007
OBJECTIVES: We sought to evaluate the risk stratification ability and incremental prognostic value of stress echocardiography over historic, clinical, and stress electrocardiographic (ECG) variables, over a wide spectrum of bayesian pretest probabilities of coronary artery disease (CAD). BACKGROUND: Stress echocardiography is an established technique for the diagnosis of CAD. However, ...
Rerkpattanapipat Pairoj - - 2007
Measurements of left ventricular function with cardiovascular magnetic resonance (CMR) at rest and during intravenous dobutamine are useful for identifying myocardial ischemia, viability, and the risk of subsequent cardiovascular events. Without ionizing radiation, intravascular iodinated contrast administration, or acoustic window limitations, CMR has emerged as a useful adjunct to transthoracic ...
Du Zhimin - - 2007
1. Physiological functions of cardiac cells require a normal cellular environment. Under pathological conditions, there is a loss of normal cellular environment due to metabolic perturbations and other abnormalities. To test the hypothesis that cellular environmental stresses can create an electrophysiological substrate for electrical disorders in the heart, we investigated ...
Nemes Attila - - 2007
The coronary flow velocity reserve (CFVR), a measure of endothelial function in coronary circulation, can be measured semi-invasively in the left anterior descending coronary artery by using stress transesophageal echocardiography (TEE). During the same stress TEE, aortic distensibility indices (elastic modulus [E(p)] and Young's circumferential static elastic modulus [E(s)]) can ...
Moreo Antonella - - 2007
Several cases of transient left ventricular apical ballooning syndrome have already been described, but the pathophysiological mechanisms of this syndrome still remain unclear. We report the case of a patient evaluated in the acute phase of apical ballooning by coronary angiography and echocardiography who was submitted to I-meta-iodobenzylguanidine (MIBG) myocardial ...
Greenwood J P - - 2007
To determine the safety and diagnostic accuracy of adenosine-stress cardiac magnetic resonance (CMR) perfusion imaging early after acute ST elevation myocardial infarction (STEMI) compared with standard exercise tolerance testing (ETT). Cross sectional observational study in a university teaching hospital. 35 patients admitted with first acute STEMI. All patients underwent a ...
Speelman Lambert - - 2007
It is generally acknowledged that rupture of an abdominal aortic aneurysm (AAA) occurs when the stress acting on the wall over the cardiac cycle exceeds the strength of the wall. Peak wall stress computations appear to give a more accurate rupture risk assessment than AAA diameter, which is currently used ...
Schneider Carsten - - 2007
AIMS: The aim of this study was to investigate whether erythropoietin (EPO) has cardioprotective effects in a chronic myocardial ischaemia model regarding strain-rate imaging parameters during dobutamine stress echocardiography (DSE). METHODS AND RESULTS: An ameroid constrictor was placed around the circumflex artery in 13 pigs to induce hibernating myocardium by ...
Aggeli Constadina - - 2007
INTRODUCTION: We tested the hypothesis that low dose dobutamine stress echocardiography (LDDSE) combined with tissue Doppler imaging (TDI) can be used for the quantitative assessment of the content of viable myocardium. METHODS: Forty-one patients with coronary artery disease and left ventricular dysfunction (ejection fraction < or =40%), already scheduled for ...
Heidenreich Paul A - - 2007
PURPOSE: Incidental cardiac irradiation during treatment of thoracic neoplasms has increased risks for subsequent acute myocardial infarction or sudden cardiac death. Identifying patients who have a high risk for a coronary event may decrease morbidity and mortality. The objective of this study was to evaluate whether stress imaging can identify ...
Alfeeli Mahmoud A - - 2007
OBJECTIVE: To perform a comparison between post-stress and rest gated single-photon emission computer tomography (SPECT) myocardial perfusion imaging (MPI) studies to assess post-stress stunning and the variables underlying this phenomenon. SUBJECTS AND METHODS: This was a prospective study of 318 consecutive adult patients undergoing stress and rest gated SPECT using ...
Chinnaiyan Kavitha M - - 2007
This retrospective study was undertaken to assess the responses to, and complications associated with, stress testing in patients with implantable cardioverter-defibrillators (ICDs). Primary end points were occurrence of malignant ventricular arrhythmias, onset of burst pacing or ICD firing, cardiopulmonary resuscitation, or death during or soon after stress testing. Secondary end ...
Sankri-Tarbichi Abdul-Ghani - - 2007
Stress-related cardiomyopathy is underdiagnosed in the white population. Recently, an increasing awareness of this syndrome was noted in the United States. Stress-related cardiomyopathy was found mostly in women after an immediate stress. The available literature has indicated excellent short-term prognosis and full recovery. We report the case of a 56-year-old ...
Khraisat Ahmad - - 2007
Stress cardiomyopathy is increasingly being described as a form of reversible left ventricular systolic dysfunction, with a characteristic shape on left ventriculography. The acute clinical, electrocardiographic and laboratory abnormalities are reminiscent of acute coronary syndrome, with nonobstructive coronary arteries on angiography. Wall motion abnormalities typical of this disease exhibit apical ...
Smith Patrick J - - 2007
Although psychologic stress has been implicated in the pathogenesis of ventricular arrhythmias, the relationship between self-reported stress and ventricular ectopy has not been evaluated under naturalistic conditions in acute post-myocardial infarction (MI) patients, a group at elevated risk for arrhythmias. Diary-reported stress was measured during 24-hour Holter monitoring in 80 ...
Knapp Małgorzata - - 2007
Left ventricular (LV) contractility impairment in coronary artery disease patients may be the effect of heart muscle hibernation due to chronic ischemia. Revascularization is the only method to restore contractile function in these patients. The time and degree of LV function improvement have not been precisely determined, and the published ...
Knapp Małgorzata - - 2007
Recent years have seen an increasing number of patients with multivessel coronary artery disease and left ventricular systolic dysfunction being qualified for cardiac surgery. Identification of patients who are likely to benefit most from revascularisation procedures poses a considerable problem. The aim of the study was to assess the value ...
Schouten O - - 2007
OBJECTIVE: Dobutamine stress echocardiography (DSE) provides an objective assessment of the presence and extent of coronary artery disease. Therefore we compared cardiac outcome in patients at high-cardiac risk undergoing open or endovascular repair of infrarenal AAA using preoperative DSE results. METHODS: Consecutive patients with >or=3 cardiac risk factors (age >70 ...
Karagiannis Stefanos E - - 2007
Myocardial viability assessment in severely dysfunctional segments by dobutamine stress echocardiography (DSE) is less sensitive than nuclear scanning. To assess the additional value of using the recovery phase of DSE after acute beta-blocker administration for identifying viable myocardium. The study included 49 consecutive patients with ejection fraction (LVEF)<or=35%. All patients ...
Egred M - - 2006
Blood oxygen level dependent (BOLD) T2* MRI detects signal variance within the myocardium based on changes in the deoxyhaemoglobin level following pharmacological stress, and it has the potential to identify areas of myocardial ischemia. The aim of the present study was to assess the utility of BOLD T2* MRI in ...
Nemes Attila - - 2007
Dobutamine stress echocardiography is an accepted tool for the diagnosis of coronary artery disease. Some investigators have claimed that 3-dimensional imaging improves the diagnostic accuracy of dobutamine stress echocardiography. The purpose of the present investigation was to examine the role of contrast echocardiography in the improvement of segmental quality and ...
Klinceva Milka - - 2007
Stress-induced myocardial stunning is defined as a syndrome of acute chest pain, ST-T changes on the ECG and transient left ventricular apical wall motion abnormalities mimicking acute myocardial infarction but with surprisingly normal coronary angiography findings. The aim of this retrospective study is to assess the prevalence of stress-induced myocardial ...
Brewington Stacy D - - 2006
Takotsubo (ampulla) cardiomyopathy, or broken heart syndrome, is an underrecognized cardiac illness that usually presents as an acute coronary syndrome in postmenopausal females. The disorder is frequently associated with episodes of mental or physical stress, implicating an abnormal cardiac response to increased catecholamines. Although death has been reported during the ...
Purgason Katey - - 2006
The link between an emotional or physical stresses and an acute cardiac event was first discovered in Japan. Stress-induced cardiomyopathy is defined as transient left ventricular dysfunction associated with apical and mid ventricular contractile abnormalities and sparing of basal segments that mimics acute myocardial infarction. This article presents an overview ...
Tendulkar Amod P - - 2006
Even though studies on isolated papillary muscles and cardiomyocytes can be applied to the mechanics of a beating heart, it is not always easy for physicians to relate these findings to clinical medicine. Thus, it is important to extend the studies to intact heart either in simulations or in animal ...
Meimoun Patrick - - 2006
OBJECTIVE: We sought to compare coronary flow velocity reserve (CFVR) with adenosine and dobutamine in patients scheduled for noninvasive evaluation of coronary artery disease. BACKGROUND: Assessment of CFVR in the distal part of the left anterior descending coronary artery (LAD) by Doppler transthoracic echocardiography (TTE) is usually performed with adenosine ...
Maruo Takeshi - - 2007
Transmural distribution of viable myocardium in the ischemic myocardium has not been quantified and fully elucidated. To address this issue, we evaluated transmural myocardial strain profile (TMSP) in dogs with myocardial infarction using a newly developed tissue strain imaging. TMSP was obtained from the posterior wall at the epicardial left ...
Heinicke N - - 2006
BACKGROUND: In the diagnosis of coronary artery disease (CAD) with Dobutamine Stress Echocardiography (DSE), regional wall motion abnormalities (RWMA) are assumed to indicate a perfusion deficit. METHODS AND RESULTS: For a more particular examination of RWMAs, we compared simultaneous echo-contrast (Optisone)-enhanced DSE (0-40 microg/kg Dobutamine, 16-segment- model) and MiBi-SPECT in ...
Raux M - - 2006
BACKGROUND: According to previous studies, a negative dobutamine stress echocardiography (DSE) test before major vascular surgery indicates that postoperative myocardial necrosis is very unlikely. We believe that the use of new cardiac troponin assays which can detect small amounts of myocardial necrosis results in a lower DSE negative predictive value ...
Siddiqui Tariq S - - 2006
BACKGROUND: The mechanism of hypotension during dobutamine stress (DS) echocardiography is unknown. The role of left ventricular outflow tract (OT) or midcavitary (MID) obstruction provoked during stress in this process remains controversial. We hypothesized that left ventricular OT obstruction would account for hypotension as opposed to MID obstruction. METHODS: Multiplane ...
Hayat Sajad A - - 2006
PURPOSE OF REVIEW: The availability of an accurate, non-invasive method for distinguishing viable from irreversibly damaged myocardium, after acute myocardial infarction or in chronic coronary artery disease, is important in clinical decision making. Such a tool would enable physicians to identify patients most likely to benefit from revascularization strategies in ...
Schinkel Arend F L - - 2006
PURPOSE OF REVIEW: The aim of this review is to provide a perspective on the role of dobutamine stress echocardiography to evaluate myocardial viability and assess prognosis in patients with ischemic left ventricular dysfunction. RECENT FINDINGS: Pooled analysis of currently available data demonstrates that dobutamine stress echocardiography provides useful information ...
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