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Wennike Nicolai - - 2010
Accurate and cost-effective techniques are required for investigating patients experiencing chest pain, given the significant workload this patient cohort represents. We determined the cost impact of stress echocardiography compared with myocardial perfusion scintigraphy and coronary angiography in the investigation of patients with chest pain deemed unsuitable for exercise treadmill testing. ...
Obradovi? Slobodan - - 2010
INTRODUCTION: Activation of haemostasis during physical stress or during myocardial ischemia could be an important mechanism to trigger coronary and stent thrombosis. We examined changes in haemostatic parameters and its association with myocardial ischemia during adenosine-exercise-SPECT (adeno-EX) stress test in coronary patients at least 4 months after coronary stenting. OBJECTIVE: ...
Legault Sylvie - - 2010
Severe obesity is associated with an increased risk of coronary artery disease (CAD). Bariatric surgery is an effective procedure for long term weight management as well as reduction of comorbidities. Preoperative evaluation of cardiac operative risk may often be necessary but unfortunately standard imaging techniques are often suboptimal in these ...
Lipton Jonathan A - - 2010
OBJECTIVE: To investigate the association between (cardiac) mortality and spatial QRS-T angle in patients undergoing dobutamine - atropine stress echocardiography (DSE) for evaluation of known or suspected coronary disease. METHODS: Between 1990 and 2003, 2347 patients underwent DSE for evaluation of coronary disease at the Erasmus Medical Center. Echocardiographic images ...
Reant Patricia - - 2010
BACKGROUND: The recent development of accurate methods to measure two-dimensional strain during dobutamine stress echocardiography has reactivated the debate as to the respective value of myocardial perfusion versus myocardial function assessment in detecting coronary stenoses. The aim of our study was to compare the effects of progressive coronary constrictions on ...
Schinkel Arend F L - - 2009
The purpose of this study was to evaluate the prognostic significance of QRS duration in patients with suspected coronary artery disease (CAD) referred for noninvasive evaluation of myocardial ischemia by dobutamine stress echocardiography. QRS duration is a prognostic marker in patients with previous myocardial infarction and/or heart failure. The relation ...
Verma Sumit - - 2009
A prospective study was performed on the utility of echocardiography in diagnosing hypotension in critically ill patients. In our study, we found that transthoracic echocardiography can help physicians determine the etiology of hypotension in a significant number of patients. Transesophageal echocardiography is useful when results obtained from transthoracic echocardiography are ...
Tio R A - - 2009
Background. In idiopathic dilated cardiomyopathy (IDC) an imbalance between myocardial oxygen consumption and supply has been postulated. Subclinical myocardial ischaemia may contribute to progressive deterioration of left ventricular function. The relation between regional myocardial perfusion reserve (MPR) and contractile performance was investigated.Methods. Patients with newly diagnosed IDC underwent positron emission ...
Sciagrà R - - 2009
AIM: Animal studies suggest an interference of dobutamine on [99mTc]sestamibi uptake. In this study dobutamine was compared to dipyridamole rest-stress [99mTc]sestamibi uptake ratio (UR). METHODS: Twenty-five patients with suspect coronary artery disease (CAD) underwent rest, dobutamine, and dipyridamole [99mTc]sestamibi SPECT at 24-h intervals and coronary angiography. UR was calculated separately ...
Sciagr? R - - 2009
AIM: Animal studies suggest an interference of dobutamine on [99mTc]sestamibi uptake. In this study dobutamine was compared to dipyridamole rest-stress [99mTc]sestamibi uptake ratio (UR). METHODS: Twenty-five patients with suspect coronary artery disease (CAD) underwent rest, dobutamine, and dipyridamole [99mTc]sestamibi SPECT at 24-h intervals and coronary angiography. UR was calculated separately ...
Fineschi Vittorio - - 2010
Emotional, physiological and physical stress is associated with increased rates of cerebrovascular events and sudden deaths. The pathophysiology of stress-induced cardiomyopathy is not well understood. Proposed mechanisms for catecholamine-mediated stunning in stress cardiomyopathy include epicardial vasospasm, microvascular dysfunction, hyperdynamic contractility with midventricular or outflow tract obstruction, and direct effects of ...
Babyak Michael A - - 2010
Previous studies of patients with stable coronary artery disease have demonstrated that decreases in the left ventricular ejection fraction (LVEF) during acute mental stress are predictive of adverse clinical outcomes. The aim of the present study was to examine the prospective relation of mental stress on clinical outcomes in a ...
Abdel-Salam Zainab - - 2010
We compared the prognostic power of three pharmacological stress echocardiography protocols for predicting improvement of global left ventricular systolic function following revascularisation. We enrolled 100 consecutive patients with significant coronary stenosis/occlusion and regional dys-synergy in the affected artery territory. Patients underwent assessment of regional and global left ventricular systolic function. ...
Maffei E - - 2010
PURPOSE: This study aimed to evaluate the diagnostic accuracy of stress electrocardiogram (ECG) and computed tomography coronary angiography (CTCA) for the detection of significant coronary artery stenosis (> or =50%) in the real world using conventional CA as the reference standard. MATERIALS AND METHODS: A total of 236 consecutive patients ...
Hahalis George - - 2009
Cardiac death remains the principal cause of mortality in beta-thalassemia major (beta-TM). Echocardiography may provide additional information, incremental to haematological profile, both for guiding chelation therapy and to assess prognosis. Between 1993 and 1995, 36 patients with beta-TM and normal cardiac function and 25 normal volunteers underwent evaluation using resting ...
Miszalski-Jamka Tomasz - - 2009
BACKGROUND: The aim of this study was to determine the incremental prognostic value of myocardial contrast echocardiography (MCE) over two-dimensional echocardiography (2DE) in patients undergoing supine bicycle stress. METHODS: Eighty-four patients with known or suspected coronary artery disease who underwent supine bicycle stress with 2DE and MCE (mean age, 58.5 ...
Lee Young-Soo - - 2009
Doppler myocardial imaging (DMI) has been suggested as a method of quantifying inducible ischemia during dobutamine stress echocardiography (DSE). Post-systolic motion (PSM) detected by DMI is related to peri-infarct ischemia during DSE. We hypothesized that PSM during DSE would predict recovery of dysfunctional myocardium after successful percutaneous coronary intervention (PCI). ...
Bansal Manish - - 2010
BACKGROUND: Perhexiline improves functional capacity in heart failure, but the mechanisms are undefined. We sought its effects on myocardial deformation in patients with viable myocardium. METHODS: Thirty-six medically-treated patients, stable at least 6 months post-infarction with LV dysfunction and myocardial viability shown by dobutamine echo (DbE) were randomised to receive ...
Leone Ornella - - 2009
BACKGROUND: Owing to the shortage of donor hearts, the criteria for acceptance have been considerably expanded. Pharmacologic stress echocardiography is highly accurate in identifying prognostically significant coronary artery disease, but brain death and catecholamine storm in potential heart donors may substantially alter the cardiovascular response to stress. This study assessed ...
Al Jaroudi Wael - - 2009
Vasodilator stress myocardial perfusion imaging (MPI) accounts for up to 50% of all stress MPI studies performed in the U.S. In 2008, the Food and Drug Administration approved regadenoson for stress testing in conjunction with MPI. Regadenoson, unlike adenosine, is a selective A(2A) agonist that is given as an intravenous ...
Cosyns Bernard - - 2009
AIMS: Myocardial contrast perfusion echocardiography (MCE) allows simultaneous assessment of perfusion and function. However, low frame rate during MCE may reduce the viewer's ability to discern contractile dysfunction. This study sought to compare MCE and left ventricular opacification (LVO) settings with regard to wall motion abnormalities (WMA) at rest and ...
Geleijnse Marcel L - - 2009
BACKGROUND: Clinical characteristics of patients, angiographic referral bias, and several technical factors may all affect the reported diagnostic accuracy of tests. The aim of this study was to assess their influence on the diagnostic accuracy of dobutamine stress echocardiography (DSE). METHODS: The medical literature from 1991 to 2006 was searched ...
Shan Ying - - 2009
BACKGROUND: Abnormal septal motion in left bundle branch block (LBBB) may compromise the interpretation of regional wall motion. Velocity vector imaging (VVI) has been proposed as an objective method to quantify regional myocardial deformation. The aim of this study was to determine whether VVI during dobutamine stress echocardiography (DSE) has ...
Kort Smadar - - 2010
OBJECTIVE: To assess the relative contribution of each myocardial segment to global systolic function during stress using real time three-dimensional echocardiography (RT3DE). BACKGROUND: During stress, global augmentation in contractility results in an increased stroke volume. The relative contribution of each myocardial segment to these volumetric changes is unknown. METHODS: Full ...
Xing Yan-qiu - - 2009
BACKGROUND: Real-time perfusion imaging (RTPI) using ultrasound contrast agents has shown good "accuracy" in detecting myocardial infarction, however its accuracy in the assessment of peri-infarct ischemia and stress echocardiography are not known. The aim of this study was to determine the accuracy of RTPI in assessment of peri-infarct ischemia during ...
Gastwirth Vanessa G - - 2009
Cases of transient left ventricular apical ballooning during dobutamine stress echocardiography have been described in the literature. Dobutamine may contribute to this phenomenon via excess catecholamine release, similar to the proposed mechanism of apical ballooning syndrome during states of extreme emotional stress. We report the first case of reversible severe ...
Hassan Mustafa - - 2009
An acute psychological stress can precipitate ventricular arrhythmias and sudden cardiac death in patients with coronary artery disease (CAD). However, the physiologic mechanisms by which these effects occur are not entirely clear. Mental stress-induced myocardial ischemia occurs in a significant percentage of the CAD population. It is unknown if the ...
C?mara Edmundo Jose Nassri - - 2009
BACKGROUND: Intraventricular obstruction (IVO) during dobutamine stress echocardiogram (DSE) may be associated with or reproduce symptoms. Predictors of IVO are not well established. METHODS: 149 patients were studied at rest and during DSE. The normal range of the left ventricular outflow tract (LVOT) velocities was investigated in 68 healthy patients. ...
Adamu Umar - - 2010
AIM: To define the prognostic impact of stress myocardial perfusion scintigraphy (MPS) in patients with angiographic exclusion of significant coronary artery disease. METHODS: Angiographic and MPS databases were matched to define patients without significant coronary artery disease by quantitative angiography (diameter stenosis <50%) who underwent stress MPS and coronary angiography ...
Ionescu Costin N - - 2009
Becker's muscular dystrophy (BMD) is one of the most common muscular dystrophy syndromes. The heart is always affected by myocardial fibrosis with early involvement of the right side. Traditionally, ECG, echocardiography and stress testing have been used to evaluate these patients. Cardiac MRI, offering superior assessment of the right side ...
Mastouri R - - 2009
Coronary artery disease remains the leading cause of death in adults in the United States. Non-invasive cardiac imaging is now central to the diagnosis and management of patients with known or suspected coronary disease. The generally accepted indications for stress testing include confirming a diagnosis of coronary disease, assessing prognosis, ...
Sadeghian Hakimeh - - 2009
AIM: To study tissue velocity imaging (TVI) and strain rate imaging (SRI) indices in akinetic nonviable and normal left ventricular (LV) inferobasal segment and effect of dobutamine infusion on these indices in nonviable segments. METHODS: The study population consisted of two groups: 25 patients (mean age 60.75 +/- 8.69 years) ...
el-Mahalawy Nagwa - - 2009
We sought to explore the value of stress-induced transient ischemic dilation (TID) of the left ventricle during dobutamine stress echocardiography, to predict the presence of multi-vessel coronary artery disease as seen by coronary angiography. We enrolled 60 patients referred to our stress echocardiography labs with ischemic-type chest pain or other ...
Chung Jina - - 2009
Remarkable advancements have taken place in echocardiography over the last decade. Real-time 3-dimensional echocardiography (RT3DE) has had an impact on numerous clinical applications, from chamber quantification to percutaneous and intraoperative procedural guidance. Novel techniques are emerging to assess left ventricular (LV) dyssynchrony. Contrast agents have undergone recent labeling changes and ...
Zhang Youhua - - 2009
BACKGROUND: Many patients require temporary inotropic support after cardiac surgery, and dobutamine is one of the commonly used drugs for this purpose. However, dobutamine infusion is frequently associated with unwanted sinus tachycardia. Selective sinus node electrical vagal stimulation through a discrete epicardial ganglionic plexus (fat pad) approach can achieve sinus ...
Cikes Maja - - 2009
AIMS: Myocardium contracts in the beginning of ejection causing outflow acceleration, resulting in asymmetric outflow velocity profiles peaking around one-third of ejection and declining when force development declines. This article aimed to demonstrate that decreased contractility in coronary artery disease (CAD) changes outflow timing and profile symmetry. METHODS AND RESULTS: ...
Ionescu Adrian - - 2009
Echo contrast agents are widely used and safe but can rarely produce serious side effects. This-to the author's knowledge-is the first detailed published case report of a patient who had a severe and complex sequence of adverse reactions within 3 min of having an intravenous infusion of Sonovue initiated, and ...
Nakajima Yoshie - - 2009
BACKGROUND: Limited information exists regarding the relationship of left ventricular diastolic filling parameters measured by Doppler echocardiography during dobutamine stress echocardiography (DSE) and stress-induced symptoms or myocardial ischemia. METHODS: To determine if there is an association between Doppler parameters of left ventricular filling and symptoms and ischemic wall motion abnormalities ...
Itani Salam - - 2009
BACKGROUND: Stress myocardial perfusion imaging (MPI) and stress echocardiography (Echo) are commonly used for the noninvasive evaluation of patients with suspected coronary artery disease (CAD). Very few studies have compared the referral patterns to these imaging modalities in terms of the clinical profile of patients, reasons for referral, and type ...
De Vriese An S - - 2009
Screening for coronary artery disease (CAD) in hemodialysis patients is hampered by contraindications and/or limitations of the available techniques in this population. Myocardial perfusion scintigraphy (MPS) using dipyridamole has been considered inaccurate due to abnormally high basal levels of adenosine in uremia that could blunt the vasodilatory response. Since dobutamine ...
UznaƄska Barbara - - 2009
BACKGROUND: Takotsubo syndrome is a primary, stress-provoked acquired cardiomyopathy mimicking acute myocardial infarction. Because of the less severe prognosis of takotsubo patients, a reliable method of predicting complete functional recovery has great practical value. CASE REPORT: A case of takotsubo syndrome is reported in a 59-year-old Caucasian woman in whom ...
Boyd John H - - 2009
PURPOSE OF REVIEW: Echocardiography has become more widely available to noncardiologists because of the technological advances in smaller, multipurpose ultrasound units with basic cardiac capabilities. In this review, we discuss the type of clinical information a trained intensivist can hope to obtain from bedside echocardiography and suggest the ways in ...
Owen Paul J - - 2009
Dialysis-induced hypotension remains a significant problem in hemodialysis (HD) patients. Numerous factors result in dysregulation of blood pressure control and impaired myocardial reserve in response to HD-induced cardiovascular stress. Episodic intradialytic hypotension may be involved in the pathogenesis of evolving myocardial injury. We performed an initial pilot investigation of cardiovascular ...
Cassar Andrew - - 2009
Despite a nonobstructive coronary angiogram, many patients may still have an abnormal coronary vasomotor response to provocation and to myocardial demand during stress. The ability of noninvasive stress tests to predict coronary vasomotor dysfunction in patients with nonobstructive coronary artery disease is unknown. All patients with nonobstructive coronary artery disease ...
Pierre-Louis Bredy - - 2009
Dual-energy x-ray absorptiometric scans of the spine and left hip were performed before stress testing for myocardial ischemia in 629 women and 136 men (mean age 63 years) with chest pain and no previous coronary artery disease. Of the 765 patients, 254 (33%) had osteoporosis, 260 (34%) had osteopenia, and ...
Scalise Filippo - - 2009
BACKGROUND: In patients with left bundle branch block (LBBB), ischemia-induced repolarization changes associated with QTc-interval shortening may be recorded during coronary angioplasty. We aimed to assess whether these repolarization changes may be predictive of severe coronary artery disease in patients with LBBB. METHODS: Fifty noninfarcted LBBB patients underwent dipyridamole stress ...
McLean Dalton S - - 2009
In the assessment of chronic myocardial infarction, echocardiography plays a vital role through the recognition of hibernating yet potentially viable myocardium that could benefit from revascularization. Echocardiography provides information through basic evaluation of cardiac structure and through evaluation of the functional response to dobutamine stress. In addition, a number of ...
Yoshitani Hidetoshi - - 2009
BACKGROUND: Although real-time three-dimensional echocardiography (RT3DE) is useful for delineating the extent and severity of stress-induced wall motion abnormalities during dobutamine stress echocardiography (DSE), it also provides simultaneous multiple two-dimensional cut planes, which may potentially improve the detection of stress-induced wall motion abnormalities. The aim of this study was to ...
Abdel-Salam Zainab - - 2009
OBJECTIVE: Pharmacological stress echocardiography is widely accepted for identifying potential contractile recovery after revascularization. We sought to compare the prognostic power of three pharmacological stress protocols for predicting contractile recovery of myocardial segments at varying degrees of dyssynergy. METHODS: We enrolled 100 consecutive patients with significant coronary stenosis amenable for ...
Bucerius Jan - - 2009
The aim of the present study was to evaluate the prognostic value of hemodynamic variables during ergometric stress testing for (99m)Tc-sestamibi myocardial perfusion scintigraphy (MPS) as compared to several patient-related variables and MPS results with regard to referral to early coronary angiography (<3 months after MPS; CA) as well as ...
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