Search Results
Results 451 - 500 of 1421
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Beller George A - - 2007
Coronary artery disease (CAD) accounts for 65% to 80% of deaths in diabetic patients. The merits of screening asymptomatic type 2 diabetic patients for either (A) the presence of coronary atherosclerosis by imaging of coronary calcification using cardiac computed tomography or (B) silent ischemia by stress myocardial perfusion imaging (MPI) ...
Ardehali Reza - - 2007
Accurate risk assessment may be helpful in decreasing cardiovascular events through more appropriate targeting of preventive measures. Traditional risk assessment may be refined with the selective use of coronary artery calcium score (CACS) or other methods of subclinical atherosclerosis measurement. This article reviews information pertaining to the clinical use of ...
Yetkin Ertan - - 2007
Coronary artery ectasia (CAE) is defined as a localized or diffuse non-obstructive lesion of the epicardial coronary arteries with a luminal dilation exceeding 1.5-fold the diameter of the normal adjacent arterial segment. The incidence of CAE has been reported to range between 2% and 4%, which might be an overestimation ...
Khorsand Aliasghar - - 2007
OBJECTIVE: This study compared the diagnostic accuracy of different approaches of case-based reasoning (CBR) for the assessment of coronary artery disease (CAD) using thallium-201 myocardial perfusion scintigraphy in comparison with coronary angiography. METHODS AND MATERIAL: For each scintigraphic image set, regional myocardial tracer uptake was obtained by polar map analysis. ...
Nemes Attila - - 2007
AIMS: The aim of the present study was to assess the relative prognostic value of coronary flow reserve (CFR) and diabetes mellitus (DM) in patients with suspected coronary artery disease (CAD). METHODS: We prospectively studied 347 inhospital patients with chest pain. Coronary angiography was performed in 281 patients (81%). All ...
Gullu Ahmet Umit - - 2007
Both genetic and environmental factors are involved in the development of coronary artery disease (CAD). The degree of contribution of each individual risk factor on CAD is unknown. The extent to which the familial occurrence of coronary heart disease is due to genetic mechanisms can be assessed in twins. In ...
Palmeri Sebastian T - - 2007
We identified 46 patients with angiographically normal coronary arteries and 16 patients with minor irregularities (luminal narrowing < or =30%) who had repeat coronary angiograms obtained at our institution during the subsequent 15-year period. On follow-up angiograms, 19 of 46 (41%) in the normal coronary group and 13 of 16 ...
Jeong Jin-Won - - 2007
BACKGROUND: The association between epicardial fat and coronary artery disease has not been evaluated. The objective of the present study was to evaluate the relationship of echocardiographic epicardial fat to the presence and severity of coronary artery disease in a clinical setting. METHODS AND RESULTS: Two hundred and three consecutive ...
Fabbian F - - 2007
BACKGROUND: Data relating carotid ultrasound (CU) to atherosclerotic damage evaluated by coronary angiography in hemodialysis patients are scarce. METHODS: We carried out a cross-sectional study in 33 uremic subjects (age 55 +/- 12 years, 22 male, 7 diabetic), who have been on dialysis for 41 +/- 48 months (range 2-192). ...
Bielak Lawrence F LF Department of Epidemiology, University of Michigan, Ann Arbor, MI 48104-3028, USA. - - 2008
Comparison of atherosclerosis and its risk factors among diverse populations may provide insights into the pathogenesis of the disease. We investigated differences in traditional coronary artery disease (CAD) risk factors and presence and quantity of coronary artery calcification (CAC), a marker of subclinical coronary atherosclerosis, between two diverse non-Hispanic white ...
Alfakih K - - 2007
OBJECTIVES: To assess the association of the angiotensin II type 2 (AT2) receptor (-1332 G/A) gene polymorphism with premature coronary artery disease (CAD) and investigate for a further role in both myocardial infarction and predominantly stenotic atherosclerosis requiring revascularisation. METHODS AND RESULTS: We investigated 885 families, which consisted of at ...
Venkatesh Prasanna Kumar - - 2007
BACKGROUND: Previous research has shown an association between higher body mass index (BMI) and lower mortality in patients with heart failure (HF). METHODS: We compared the prevalence of angiographic coronary artery disease (CAD) and risk factors in obese versus non-obese patients with HF. Eighty-four consecutive patients with systolic HF who ...
Charytan David - - 2007
BACKGROUND: Long-term dialysis patients have a high incidence of myocardial infarction and cardiovascular death, but the incidence of coronary artery disease (CAD) in asymptomatic patients, distribution of coronary obstruction, and relationship between lesion location and mortality are unknown. METHODS: We studied 67 asymptomatic hemodialysis patients who volunteered for coronary angiography. ...
Speidl Walter Stefan - - 2007
Inflammatory processes play a role in the onset of acute cardiovascular events associated with activation of the coagulation system whereas the fibrinolytic system may prevent local thrombus formation. We compared 25 patients with premature coronary artery disease (CAD) (first ST-elevation myocardial infarction, < 55 years old) with 25 sex-matched patients ...
Dorbala Sharmila - - 2007
Our aim was to determine the value of vasodilator left ventricular ejection fraction (LVEF) reserve (stress ejection fraction - rest ejection fraction) in evaluating the magnitude of myocardium at risk and the anatomic extent of underlying severe coronary artery disease (CAD). METHODS: We studied 510 consecutive patients with suspected CAD ...
Butler Javed - - 2007
BACKGROUND: The extent and nature of overall coronary artery disease (CAD), defined as the cumulative stenotic and nonstenotic, calcified and noncalcified atherosclerosis burden, are underestimated by invasive coronary angiography (ICA) and more accurately quantified with intravascular ultrasound. Multidetector row computed tomography (MDCT) is inferior to intravascular ultrasound but may constitute ...
Guzik Przemysław - - 2007
BACKGROUND: Typical chest pain and ECG changes suggest the presence of myocardial ischaemia in cardiac syndrome X (SX) patients and resemble the symptoms observed in subjects with atherosclerotic coronary artery disease (CAD). AIM: To compare the results of exercise treadmill tests (ETT), 24-hour ECG recordings and echocardiography in SX and ...
Stone Peter H - - 2007
AIM: We performed serial intracoronary studies of patients with stable coronary artery disease (CAD) to investigate the relationships among baseline endothelial shear stress (ESS), CAD progression, and vascular remodelling. Local haemodynamic factors are critical determinants of plaque progression, vascular remodelling, and clinical CAD manifestations. METHODS AND RESULTS: The 3-D anatomy ...
Mieres Jennifer H - - 2007
The aim of this study is to prospectively evaluate the clinical value of electrocardiographically gated single-photon emission computed tomographic myocardial perfusion scintigraphy (MPS) imaging in a cohort of postmenopausal women with symptoms suggestive of ischemic heart disease. Forty-six postmenopausal women with no history of coronary artery disease (CAD), but with ...
Shishehbor Mehdi H - - 2007
We examined the safety and efficacy of nonculprit multivessel compared with culprit-only stenting in patients with multivessel disease presenting with unstable angina or non-ST-segment elevation myocardial infarction (non-ST-segment elevation acute coronary syndromes [NSTE-ACS]). In patients presenting with NSTE-ACS, multivessel coronary artery disease (CAD) is associated with adverse outcome. Patients with ...
Wang Hai-Ya - - 2007
We sought to investigate whether numbers and activity of circulating endothelial progenitor cells (EPCs) correlate with severity of coronary stenosis as well as cardiovascular risk factors in patients with stable coronary artery disease (CAD). Number of circulating EPCs was analyzed in 104 consecutive patients with proven or clinically suspected CAD. ...
Onishi Toshinari - - 2007
BACKGROUND: A positive myocardial velocity during isovolumic relaxation phase (V(IR)) detected by spectral tissue Doppler imaging has been shown to indicate ischemic myocardium. We sought to examine the diagnostic value of positive V(IR) for detecting coronary artery disease (CAD) in patients with chest pain and apparently normal left ventricular contraction. ...
Bots Michiel L - - 2007
AIMS: Measurement of change in carotid intima-media thickness (CIMT) has been proposed as an alternative for the occurrence of cardiovascular (CV) events in the assessment of therapeutic interventions. Nevertheless, criticism has been voiced based on observations indicating a weak relation between CIMT and coronary atherosclerosis as well as on the ...
Futamatsu H - - 2007
Cardiac magnetic resonance imaging (cMRI) is a promising non-invasive technique to assess the presence of coronary artery disease (CAD), which is free of ionizing radiation and iodine contrast. cMRI can detect CAD by angiographic methods or indirectly by perfusion stress techniques. While coronary angiography by cMRI remains limited to research ...
De Winter O - - 2008
AIM: The aim of this study was to investigate the prognostic value of myocardial perfusion and function SPECT imaging in patients with coronary artery disease (CAD) and poor left ventricular (LV) function. METHODS: We studied 261 patients (231 men, age 66+/-10 years) with CAD and a resting LV ejection fraction ...
Schietinger Brian J BJ Department of Medicine, Cardiovascular Division, University of Virginia Health System, Lee Street, Box 800170, Charlottesville, VA 22908, - - 2007
New left ventricular systolic dysfunction affects 500,000 Americans and coronary artery disease (CAD) is responsible for two-thirds of cases. Identifying CAD has both prognostic and therapeutic implications. We evaluated the ability of late gadolinium enhancement (LGE) by cardiovascular magnetic resonance imaging (CMR) to detect CAD as the etiology of recent ...
Moir, William Stuart
Contrast echocardiography has an established role for enhancement of the right heart&#13;Doppler signals, the detection of intra-cardiac shunts, and most recently for left&#13;ventricular cavity opacification (LVO). Over the past decade, because of the&#13;simultaneous evolution of micro-bubble engineering and contrast specific imaging&#13;modalities, the use of intravenously administered micro-bubbles to traverse the&#13;myocardial ...
Slomka Piotr J - - 2007
BACKGROUND: We sought to determine the diagnostic performance of a recently developed combined supine-prone quantification algorithm for myocardial perfusion single photon emission computed tomography (MPS) for the detection of coronary artery disease (CAD) in women. METHODS AND RESULTS: Consecutive MPS scans of women without known CAD and coronary angiography within ...
Makaryus Amgad N - - 2007
Stress myocardial perfusion imaging (MPI) plays an important role in the diagnostic and prognostic assessment of coronary artery disease (CAD) in patients of all age groups who are undergoing assessment prior to non-cardiac surgery. MPI may utilise exercise treadmill or pharmacological stress testing. While MPI has been evaluated in a ...
Miura Shin-ichiro - - 2007
Coronary artery disease (CAD) is the most important cause of death in the industrialized world. After experimental myocardial infarction, numerous dilated vessels appear in the border zone between the infarct and noninfarct areas. Angiogenic therapy has been widely regarded as an attractive approach for both treating CAD and enhancing arterioprotective ...
Geluk C A - - 2007
The use of invasive procedures has mostly been studied in retrospective (multi)- national registries. Limited evidence exists on the association between microalbuminuria and coronary artery disease (CAD). The incidence of major adverse cardiac events (MACE) and invasive cardiac procedures was registered between 1997 and 2003 in 8139 subjects, without prior ...
Ishikawa Nobuki - - 2007
: The authors examined parameters of cardiovascular function using Starfish and deep pericardial sutures (DPS) in a beating heart porcine model and to clarify toleration of right ventricular function with Starfish in lateral wall displacement. : Eight healthy pigs were used. In addition to normal pressure monitor catheters, a Swan-Ganz ...
Schuijf J D - - 2007
BACKGROUND: Plaque composition rather than degree of luminal narrowing may be predictive of acute coronary syndromes (ACS). The purpose of the study was to compare plaque composition and distribution with multi-slice computed tomography (MSCT) between patients presenting with either stable coronary artery disease (CAD) or ACS. METHODS: MSCT was performed ...
Wang Tracy Y - - 2007
Anemia is common among patients with coronary artery disease (CAD) and portends a higher risk of short- and long-term mortality, major adverse cardiac events, and bleeding complications. Blood transfusion has long been the cornerstone of therapy for anemia; however, its benefit in patients with CAD is controversial and the appropriate ...
Konstantino Yuval - - 2007
BACKGROUND: Biomarkers of atherosclerosis are emerging as a potential tool for assessment of coronary artery disease (CAD) patients. As acute coronary syndrome (ACS), and stable CAD are distinguished in their pathophysiology it is conceivable that they are also characterized by different biomarkers of atherosclerosis. METHODS: We systematically reviewed the literature ...
Rossi Gian Paolo - - 2007
Experimental and observational studies support a role of plasma homocysteine levels (tHcy) in coronary artery disease (CAD). In the GENICA (Genetic and Environmental factors In Coronary Atherosclerosis) study, we found that high tHcy predicted cardiovascular mortality in hypertensive, but not in normotensive, patients independently of CAD and history of myocardial ...
Foroutan Seyed Kazem - - 2007
INTRODUCTION: We evaluated erectile function of men with coronary artery disease (CAD) and the relation between the degree of erectile dysfunction (ED) and the extent of coronary artery stenosis on cardiac angiography. MATERIALS AND METHODS: Nondiabetic men with CAD documented by angiography were evaluated for ED. Erectile function was assessed ...
Barnason Susan - - 2007
The preoperative status of coronary artery bypass graft (CABG) surgical patients is often evaluated as a means to assess operative risk for mortality and morbidity and to inform how preoperative status influences or predicts outcomes following CABG surgery. The purpose of this study was to examine the influence of coronary ...
Martini D Bortolo - - 2007
Whether to a greater or lesser extent, genetics often plays an important role in the development of cardiovascular diseases. Here we report a newly identified family with familial coronary artery disease (CAD) and left ventricular non-compaction (LVNC). A 52-year-old male with acute coronary syndrome, in whom LVNC had been found ...
Hida Satoshi - - 2007
BACKGROUND: Although transient left ventricular (LV) dilation is a well-known marker for extensive coronary artery disease (CAD), few studies have performed quantitative analysis of LV function after stress and at rest to detect extensive CAD. METHODS AND RESULTS: Poststress and resting gated single photon emission computed tomography (SPECT) was performed ...
Granér Marit - - 2007
BACKGROUND: Insulin resistance (IR) is frequently observed in patients with coronary artery disease (CAD). Aim. To examine the association between IR and severity and extent of CAD. METHODS: Quantitative coronary angiography (QCA) was used to assess coronary atherosclerosis in 107 patients with clinically suspected CAD. QCA-derived indexes reflecting CAD severity, ...
Vizzardi E - - 2007
AIM OF THE STUDY: Previous studies have suggested that total plasma homocysteine (HCY) is an important cardiovascular risk factor because of its interaction with vascular smooth muscle cells, endothelium function, plasma lipoprotein, coagulation factors and platelets. The aim of this study was to evaluate a possible relationship between HCY levels ...
Peels J O J - - 2007
For patients suffering from complex coronary artery disease (CAD) with or without concomitant valve disease, no evidence is available in the current guidelines to propose a predefined treatment regimen. We sought to assess the clinical impact of an unconventional or extended definition of the hybrid approach that combines percutaneous coronary ...
Oliveira Joselina L M - - 2007
Exercise echocardiography (EE) is an established method to diagnose coronary artery disease (CAD). Chronotropic incompetence (CI) during the EE may be a marker of myocardial ischemia. The purpose of this investigation was to evaluate the additive value of CI during EE in CAD diagnosis. Between 2000 and 2006, 4042 patients ...
Rubinshtein Ronen - - 2007
We examined the extent of coronary artery disease (CAD) on 64-slice contrast-enhanced multidetector computed tomography in patients who underwent investigation of a chest pain syndrome who had a zero or low coronary calcium score (CS). In 668 consecutive patients with chest pain syndromes (39% with acute presentation, 61% with long-term ...
Pundziute Gabija - - 2007
OBJECTIVES: This study sought to determine the prognostic value of multislice computed tomography (MSCT) coronary angiography in patients with known or suspected coronary artery disease (CAD). BACKGROUND: It is expected that MSCT will be used increasingly as an alternative imaging modality in the diagnosis of patients with suspected CAD. Data ...
Schmid Jean-Paul - - 2007
Whole-body water immersion leads to a significant shift of blood from the periphery to the intrathoracic circulation, followed by an increase in central venous pressure and heart volume. In patients with severely reduced left ventricular function, this hydrostatically induced volume shift might overstrain the cardiovascular adaptive mechanisms and lead to ...
Otsubo Hitoshi - - 2006
BACKGROUND: In a retrospective study portable-type signal-averaged electrocardiography (SAECG) with dipyridamole stress was found to identify patients with coronary artery disease (CAD) at their bedside with high sensitivity and specificity, so the utility of this method was prospectively investigated in the present study. METHODS AND RESULTS: Standard 12-lead QRS wave ...
Brener Sorin J - - 2006
BACKGROUND: In patients with coronary artery disease (CAD), therapies designed to prevent clinical events are not always associated with significant reduction in coronary obstruction, as measured by quantitative coronary angiography. We set out to explore the relationship between quantitative coronary angiography parameters, baseline characteristics, and clinical events in a large ...
Schuijf Joanne D - - 2006
OBJECTIVES: The aim of this study was to perform a head-to-head comparison between multi-slice computed tomography (MSCT) and myocardial perfusion imaging (MPI) in patients with an intermediate likelihood of coronary artery disease (CAD) and to compare non-invasive findings to invasive coronary angiography. BACKGROUND: Multi-slice computed tomography detects atherosclerosis, whereas MPI ...
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