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Kloch-Badelek Malgorzata M aThe First Department of Cardiology, Interventional Electrocardiology and Hypertension, Jagiellonian University Medical College, Krakow, Poland bResearch Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium cHypertension Division, Department of Internal Medicine, University Clinical Centre Ljubljana, Ljubljana, Slovenia dThe Department of Medicine, University of Padova, Padova, Italy eHypertension Unit, Department of Hypertension and Diabetology, Medical University of Gdansk, Gdansk, Poland fThe Institute of Internal Medicine, Novosibirsk, Russian Federation. *Both authors contributed equally to this - - 2014
Understanding to what extent genetic factors influence diastolic Doppler indexes is an important issue in view of the relation of left ventricular diastolic dysfunction with outcome. We, therefore, investigated the heritability of left ventricular diastolic traits and the composite diastolic score in nuclear families recruited from the general population. In ...
Stöllberger Claudia C Hospital Rudolf Foundation, Vienna, - - 2014
"Himalayan P waves," are reported in congenital heart disease and cardiomyopathies. We report a family with hypertrophic cardiomyopathy, Himalayan P waves, extensive focal right atrial wall thickening and left ventricular hypertrabeculation/noncompaction (LVHT). The father received a pacemaker and underwent heart transplantation because of hypertrophic cardiomyopathy. His daughters showed Himalayan P ...
Yuan Li L Department of Ultrasonography, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Hubei Provincial Key Laboratory of Molecular Imaging, Wuhan 430022, People's Republic of - - 2014
Hypertrophic cardiomyopathy (HCM) and left ventricular noncompaction (LVNC) are both genetically determined and familial diseases that possess variable but overlapping genetic defects. Previous literature has mostly reported their occurrences as either separate disorders in different members of a family or coexisting entities in sporadic cases rather than familial cases. This ...
Bangash Fatima A FA Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6 BQ, - - 2014
A novel LDL-receptor gene variant was found responsible for previously undetected familial hypercholesterolaemia and acute myocardial infarction in a young man.
Henry Jason T JT Minneapolis Heart Institute Foundation at Abbott Northwestern Hospital, Minneapolis MN and University of North Dakota Medical School, Grand - - 2014
Background-Transfer for primary percutaneous coronary intervention (PCI) is superior to fibrinolysis if performed in a timely manner but frequently requires dislocation of patients and their families from their local community. Although patient satisfaction is increasingly viewed as an important quality indicator, there are no data on how emergent transfer for ...
Al-Rasadi Khalid K Department of Clinical Biochemistry, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Sultanate of Oman; Department of Clinical Physiology, Sultan Qaboos University Hospital, Muscat, Sultanate of - - 2014
Subjects with Familial hypercholesterolemia are at increased risk for cardiac events such as premature myocardial infarction and early death from coronary heart disease, especially in patients with severe forms of the disease if left unattended. Therefore, there is an ardent need for the early diagnosis followed by aggressive therapeutic intervention ...
Magida Jason A JA Department of Molecular, Cellular and Developmental Biology, BioFrontiers Institute University of Colorado at Boulder, Boulder, CO, - - 2014
Familial hypertrophic cardiomyopathy (HCM) is largely caused by dominant mutations in genes encoding cardiac sarcomeric proteins, and it is etiologically distinct from secondary cardiomyopathies resulting from pressure/volume overload and neurohormonal or inflammatory stimuli. Here, we demonstrate that decreased left ventricular contractile function in male, but not female, HCM mice is ...
Petryka Joanna J 1Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, United Kingdom; NIHR Cardiovascular Biomedical Research Unit, Royal Brompton Hospital and Imperial College, London, United Kingdom; Institute of Cardiology, Warsaw, - - 2014
-Crypts or clefts in the left ventricular inferobasal myocardium have been detected by cardiovascular magnetic resonance (CMR), but the extent to which they represent pre-phenotypic markers of hypertrophic cardiomyopathy (HCM) or incidental structural variants remains controversial. -We examined retrospectively the routine vertical long axis cines in 686 consecutive patients (48±20 ...
Erdal Muhammed M Department of Cardiology and Aviation Medicine Center, Etimesgut Military Hospital, Ankara-Turkey. - - 2014
Coronary artery disease (CAD) is one of the most incapacitating causes at military or civilian aviation. Aircrew population is crowding in number in our country. We aimed to identify the clinical features that could predict CAD in aircrew. We retrospectively analyzed medical recordings of 26 aircrew (age 43.57±5.2) whose CAD ...
James Stephanie S Department of Cardiology, St Vincent's University Hospital, Dublin, - - 2014
This case is of a 29-year-old man with progressive familial intrahepatic cholestasis type 1 also known as Byler's disease. At the age of 21, our patient developed non-ischaemic dilated cardiomyopathy. Cardiac MRI demonstrated global wall thinning, with significant areas of myocardial fibrosis in the mid and epicardial walls from base ...
Amano Yasuo Y From the Departments of *Radiology, and †Cardiology, Nippon Medical School, Tokyo, - - 2013
This study aimed to determine the relationship between delayed enhancement magnetic resonance imaging (DE MRI) and ventricular tachyarrhythmia in patients with hypertrophic cardiomyopathy (HCM) with basal septal hypertrophy and preserved ejection fraction (EF). One hundred seven patients with HCM with basal septal hypertrophy and EF greater than 50% underwent cine ...
Erdmann Jeanette J 1] Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, 23562 Lübeck, Germany [2] German Centre for Cardiovascular Research (DZHK), partner site Hamburg/Lübeck/Kiel, 23562 Lübeck, Germany - - 2013
Myocardial infarction, a leading cause of death in the Western world, usually occurs when the fibrous cap overlying an atherosclerotic plaque in a coronary artery ruptures. The resulting exposure of blood to the atherosclerotic material then triggers thrombus formation, which occludes the artery. The importance of genetic predisposition to coronary ...
Magnussen Costan G - - 2013
In a prospective cohort of 181 individuals followed up since childhood - when aged 9, 12 and 15 years - patients with a family history of premature coronary heart disease (n=18) had higher left ventricular mass index in adulthood - at mean age of 31 years - compared with those ...
Tong L J - - 2013
Cardiovascular disease is increasingly recognized as an important cause of morbidity and mortality in captive chimpanzees (Pan troglodytes). This report records 2 cases of sudden cardiac death in closely related subadult captive chimpanzees with marked replacement fibrosis and adipocyte infiltration of the myocardium, which resemble specific atypical forms of the ...
Gokalp Selman - - 2013
Myocardial bridging is usually seen in the setting of hypertrophic cardiomyopathy or left ventricular hypertrophy. It is rarely reported in an asymptomatic patient with an otherwise structurally normal heart. Familial subaortic stenosis is also a rare entity, and its mode of inheritance is still unknown. Here, we described the case ...
James Cynthia A - - 2013
OPINION STATEMENT: Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is an inherited cardiomyopathy characterized by life-threatening ventricular arrhythmias and slowly progressive ventricular dysfunction. Treatment for families with ARVD/C is directed toward prevention of sudden cardiac death, prevention or delay of disease progression, and adjustment to life with a lifelong chronic genetic disease. ...
Sherling Kelley Willis - - 2013
Isolated Left Ventricular Non Compaction Cardiomyopathy (LVNCC) is a rare genetic cardiomyopathy characterized by a thickened left ventricle with two distinct layers - an inner noncompacted (spongy) layer and an outer compact (dense) layer. The spongy layer is composed of deep intertrabecular recesses. Familial and sporadic forms are known to ...
Sharkey Scott W - - 2013
The investigators describe the occurrence of an episode of acute tako-tsubo cardiomyopathy in a 51-year-old woman, which was followed, only days later, by an episode of acute tako-tsubo cardiomyopathy in her 74-year-old mother. The mother and daughter had distinctly different left ventricular contraction patterns, yet the left anterior descending coronary ...
Ahmadi Seyed Hossein - - 2013
Although coronary artery disease (CAD) is not common among individuals younger than 40-45 years of age, a small percentage of this age group needs to undergo surgical revascularization because of CAD. Why some people are at higher risk of developing premature CAD is not clearly known. Increased number of traditional ...
Bezgin T - - 2013
Acute myocardial infarction (AMI) is a rare but often catastrophic event during pregnancy, delivery or puerperium, leading to a high mortality rate. It has different pathogenic mechanisms, such as atherosclerosis, vasospasm, thrombosis and coronary dissection. Although MI has been reported in pregnant women at all stages of pregnancy and postpartum, ...
Quarta Candida Cristina - - 2012
Abstract Amyloidotic cardiomyopathy is still a widely underdiagnosed condition that usually requires endomyocardial biopsy (EMB) for a definite diagnosis. (99m)Tc-3,3-diphosphono-1,2-propanodicarboxylic acid ((99m)Tc-DPD) has proven highly sensitive for detecting amyloidotic cardiomyopathy due to transthyretin-related amyloid deposition. Herein we report the first description of the (99m)Tc-DPD scintigraphy profile in a patient with ...
Cho Hyun Jun - - 2012
A 53-year-old man complained of orthostatic, non-rotating dizziness, and chronic watery diarrhea of several years duration. His nerve-conduction velocity test revealed peripheral sensory-motor polyneuropathy and he showed an autonomic function abnormality. Echocardiographic examination showed ventricular and atrial wall thickening with a granular "sparkling" appearance. Left ventricular systolic function was preserved ...
Ekberg Sara - - 2012
The chance of surviving an acute myocardial infarction (MI) has increased greatly but many persons still die as a consequence of MI. We assessed the familiality of suffering fatal MI using Swedish registry data. All 4,239 sib-pairs (n = 8,478) where both siblings had suffered an MI and who were born 1932 ...
Yasukawa Hideo H Division of Cardiovascular Medicine; Department of Internal Medicine; Kurume University School of Medicine; Kurume, Japan ; Cardiovascular Research Institute; Kurume University School of Medicine; Kurume, - - 2012
The suppressors of cytokine signaling (SOCS) family of proteins are cytokine-inducible inhibitors of Janus kinase (JAK)-signal transducer and activator of the transcription (STAT) signaling pathways. Among the family, SOCS1 and SOCS3 potently suppress cytokine actions by inhibiting JAK kinase activities. The generation of mice lacking individual SOCS genes has been ...
Chen Hong-Hui - - 2012
The healthiness of the heart is import to human for leading a healthy life. Some of the abnormal conditions of heart could be detected by the heart sound. For example, heart murmur is one of the conditions possibly resulting from the illness of heart valves. In this work, we propose ...
Biffi Mauro - - 2012
BACKGROUND: -Phrenic Nerve Stimulation (PNS) is a common complication of cardiac resynchronization therapy (CRT) when left ventricular (LV) pacing occurs via a coronary vein. The purpose of this study was to evaluate effects of bipolar electrode spacing on PNS and LV pacing threshold. METHODS AND RESULTS: -Electrophysiology (EP) catheters with ...
Al Montasir Ahmed - - 2012
Familial hypercholesterolemia is a single gene disorder. It has autosomal dominant pattern of inheritance. We report a 28-year-old man who presented with acute myocardial infarction. He had xanthomas and an elevated serum low density lipoprotein cholesterol (LDL-C). His only sibling, 32-year-old brother have similar cutaneous lesions and lipid profile. His ...
Salminen-Tuomaala Mari - - 2012
Background. Patients recovering from a myocardial infarction (MI) are faced with a number of serious challenges. Aim. To create a substantive theory on myocardial infarction patients' coping as a continuum. Methods. Grounded theory method was used. Data were collected by using individual interviews. The informants were 28 MI patients. Results. ...
Cognet Thomas T Department of Cardiology, University Hospital of Rangueil, 1 Avenue Jean Poulhès, 31059 Toulouse Cedex 9, France ; Cardiac Imaging Center, University Hospital of Toulouse, Toulouse, - - 2012
Myocarditis can lead to acute heart failure, cardiogenic shock, or sudden death and later, dilated cardiomyopathy (DCM) with chronic heart failure. We report the cases of two DCM induced by acute and past myocarditis in the same family and expressed by its two main complications within few weeks: an hemodynamic ...
Bulakci Mesut - - 2011
Mediastinal lipomatosis (ML) is a benign condition characterized by the accumulation of mature adipose tissue within the mediastinum. ML is usually associated with Cushing syndrome and obesity. Most patients are asymptomatic, but some have thoracic pain, dyspnea, cough, dysphonia, dysphagia, and supraventricular tachycardia. We report a case of ML compressing ...
Brink Eva - - 2011
Brink, E., Alsén, P. & Cliffordson, C. (2011). Validation of the Revised Illness Perception Questionnaire (IPQ-R) in a sample of persons recovering from myocardial infarction - the Swedish version. Scandinavian Journal of Psychology. When people's health is threatened, they generally develop illness perceptions to make sense of their illness. The ...
Barnett Phil - - 2011
Cardiovascular diseases are the leading cause of mortality, morbidity, hospitalization and impaired quality of life. In most, if not all, pathologic cardiac ischemia ensues triggering a succession of events leading to massive death of cardiomyocytes, fibroblast and extracellular matrix accumulation, cardiomyocyte hypertrophy which culminates in heart failure and eventually death. ...
Navarro-Manchón Josep J Departamento de Cardiología, Hospital La Fe, Valencia, - - 2011
Left dominant arrhythmogenic cardiomyopathy (LDAC) exhibits characteristic phenotypic and genetic features which were found in the five Spanish family members described in this study. Triggered by a cold, a young man presented with a ventricular tachycardia of left ventricular origin and left ventricular late gadolinium enhancement. His resting ECG showed ...
Bell Robert M - - 2011
In the late 19th century, a number of investigators were working on perfecting isolated heart model, but it was Oscar Langendorff who, in 1895, pioneered the isolated perfused mammalian heart. Since that time, the Langendorff preparation has evolved and provided a wealth of data underpinning our understanding of the fundamental ...
Woods D R - - 2011
Palpitations at high altitude have been experienced, but seldom recorded, for centuries. The hypoxia, sympathetic activation and alkalosis of altitude predispose to cardiac ischaemia and arrhythmia. Indeed, sudden cardiac death is responsible for 30% of all deaths during mountain sports at altitude. This article reviews the literature to date on ...
Singh N K - - 2011
Infective endocarditis affecting the tricupid valve due to rupture of non-coronary sinus of Valsalva is distinctly rare. We are reporting such a rare case, presenting with recurrent ill sustained ventricular tachycardia.
Moondra Vaibhav - - 2011
Atrioventricular nodal reentrant tachycardia (AVNRT) is usually associated with a good prognosis. This is a case of a 57-year woman who presented with supraventricular tachycardia that spontaneously deteriorated to polymorphic ventricular tachycardia (PVT). The PVT terminated without treatment after 16 seconds. Extensive cardiac evaluation including echocardiography, stress testing, coronary angiography, ...
Shaaraoui Mustaphasahim - - 2011
Suppression of Ventricular Tachycardia With Dronedarone. Introduction: Dronedarone is a multichannel blocker with similar electrophysiological properties to amiodarone. Dronedarone has not been studied in humans as an agent to suppress ventricular arrhythmias. Methods: This case report describes the dramatic antiarrhythmic effects of dronedarone in a patient with nonischemic cardiomyopathy and recurrent ...
Arimoto Takanori - - 2010
We report the case of a patient who suffered from early morning nonsustained ventricular tachycardia. Clinical ventricular tachycardia without coronary spasm was reproducibly induced only by injection of acetylcholine in the right coronary artery. A good pace mapping site with 30 ms early ventricular activity was present in the right ...
Khan Aamir H - - 2010
Entrainment from the right ventricular (RV) apex and the base has been used to distinguish atrioventricular reentrant tachycardia (AVRT) from atrioventricular nodal reentry tachycardia (AVNRT). The difference in the entrainment response from the RV apex in comparison with the RV base has not been tested. Fifty-nine consecutive patients referred for ...
Jat Kana Ram - - 2011
Arrhythmias in children can be classified according to their effect on central pulse: Fast pulse rate - tachyarrhythmia; Slow pulse rate - bradyarrhythmia; and Absent pulse is pulseless arrest (cardiac arrest). Tachyarrythmia may be narrow complex tachycardia (QRS duration ≤0.08 s): sinus tachycardia (ST), supraventricular tachycardia (SVT), atrial flutter or Wide-complex ...
AlMahameed Soufian T - - 2010
Right ventricular pacing (RVP) during supraventricular tachycardia produces progressive QRS fusion before the QRS morphology becomes stable. This transition zone (TZ) may provide useful information for differentiating orthodromic reciprocating tachycardia (ORT) from atrioventricular nodal reentrant tachycardia and atrial tachycardia independent of entrainment success. We studied the effect of properly timed ...
Rosman Jonathan Z - - 2011
The beginning of ventricular overdrive pacing (VOP) during supraventricular tachycardia (SVT) accurately distinguishes orthodromic reentrant tachycardia (ORT) from atrioventricular nodal reentrant tachycardia (AVNRT) even when pacing terminates tachycardia. Tachycardia resetting most often occurs during this transition zone (TZ) of QRS fusion in ORT and after this TZ in AVNRT. The ...
Abu-Omar Yasir - - 2010
Cardiac tumors are rare and have a known association with ventricular dysrhythmias, especially ventricular tachycardia. We report a case of intractable ventricular tachycardia in a middle-aged man developing on a background of known, presumed benign, cardiac neoplasm. The ventricular tachycardia was controlled with long-term medical therapy. Surgical resection of the ...
Alvarez E - - 2010
Results of a comparative analysis between Heart Rate (HR) patterns occurring before the onset of Paroxysmal Ventricular Tachycardia (PVT) and from healthy subjects are shown. Two study groups were made after electrocardiographic dynamical monitoring (Holter) of volunteers. The first group includes 100h from 27 healthy control subjects, and the second ...
Bernier Martin - - 2010
We present a case of a 70-year-old man who received an inappropriate implantable cardioverter-defibrillator shock for sinus tachycardia falling outside of the ventricular tachycardia zone. This occurred after termination of supraventricular tachycardia falling into the ventricular fibrillation zone by antitachycardia pacing. Particularities of the programming algorithms are reviewed.
Gujja Karthik - - 2010
Atropine is commonly a used pre anesthetic medication. A 22-year-old female with history of unexplained recurrent syncope during electrophysiology developed inducible ventricular arrhythmias when 0.5 mg of atropine was injected intravenously to improve this Wenckebach. There is a significant change in the autonomic influence on the heart prior to idiopathic ...
Schreiber Doreen - - 2010
Idiopathic ventricular arrhythmias occur in patients without structural heart disease. They can arise from a variety of specific areas within both ventricles and in the supravalvular regions of the great arteries. Two main groups need to be differentiated: arrhythmias from the outflow tract (OT) region and idiopathic left ventricular, so-called ...
Nair Krishnakumar - - 2010
A narrow QRS tachycardia with eccentric atrial activation is presented with features favoring an orthodromic atrioventricular re-entrant tachycardia including an extranodal paraHisian response, and a short corrected post-pacing interval to tachycardia cycle length difference following right ventricular entrainment. However, during entrainment, the H-H interval was entrained by the pacing train ...
Masihi Kocharian Arman - - 2010
Left ventricle non-compaction (LVNC) or persistence of spongy myocardium is a rare form of congenital cardiomyopathy which presents with cardiac failure, thromboembolic events, arrhythmia and sudden death. We report a family with two deceased children and two alive offspring diagnosed with left ventricular (LV) non-compaction. A 9-year-old boy and a ...
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