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Results 451 - 500 of 1824
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Johnson Nils P - - 2011
BACKGROUND: The initial electrocardiogram (ECG) in Takotsubo cardiomyopathy (TC) can mimic an acute, anterior ST-segment elevation myocardial infarction (STEMI). Given the profound and immediate treatment differences between TC and STEMI, it would be clinically valuable to distinguish them using ECG criteria. METHODS: Presenting ECGs for proven cases of TC and ...
Harris Ben - - 2011
STUDY OBJECTIVE: Multiple studies have linked emergency department (ED) crowding to delays in patient care, such as treatment with antibiotics and analgesics. Multiple studies have also demonstrated the benefit of timely percutaneous coronary intervention for patients with acute ST-segment elevation myocardial infarction (STEMI). We therefore study whether increased occupancy rates ...
Bogaard Margot D - - 2011
AIMS: The maximum rate of left ventricular (LV) pressure rise (dP/dt(max)) has been used to assess the acute haemodynamic effect of cardiac resynchronization therapy (CRT). We tested the hypothesis that LV dP/dt(max) predicts long-term clinical outcome after initiation of CRT. METHODS AND RESULTS: This was a retrospective observational multicentre study ...
Sato Yuichiro Z YZ Department of Pediatrics and Medicine, Rady Children's Hospital, University of California San Diego, School of Medicine, La Jolla, CA, United - - 2013
Endomycocardial biopsies have demonstrated that subclinical myocarditis is a universal feature of acute Kawasaki disease (KD). We investigated biochemical evidence of myocardial strain, oxidative stress, and cardiomyocyte injury in 55 acute KD subjects (30 with paired convalescent samples), 54 febrile control (FC), and 50 healthy control (HC) children by measuring ...
Hochholzer Willibald - - 2011
BACKGROUND: High-sensitivity cardiac troponin assays have better analytical precision and sensitivity than earlier-generation assays when measuring cardiac troponin at low concentrations. We evaluated whether use of a high-sensitivity assay could further improve risk stratification compared with a standard cardiac troponin assay. METHODS: We enrolled consecutive patients presenting with acute chest ...
Friehling Mati - - 2011
There are ongoing efforts to optimize patient selection criteria for cardiac resynchronization therapy (CRT). In this regard, the relationship between acute change in left ventricular synchrony (LV) after CRT and patient outcome remains undefined. A novel protocol was designed to evaluate acute change in left LV synchrony after CRT using ...
Atzema Clare L - - 2011
Coronary artery disease is the most common cause of death in the Western world, and being married decreases the risk of death from cardiovascular causes. We aimed to determine whether marital status was a predictor of the duration of chest pain endured by patients with acute myocardial infarction before they ...
Hachinohe Daisuke - - 2011
The aim of this study was to compare clinical outcomes among early invasive (EI), deferred invasive (DI), and conservative strategies in patients with acute non-ST-segment elevation myocardial infarction (NSTEMI) and chronic kidney disease (CKD). High-risk patients with NSTEMI are believed to fare better with an EI strategy, but the optimal ...
Y-Hassan Shams - - 2011
Bromocriptine-induced coronary spasm (BICS) causing myocardial infarction has been reported. Association between BICS and Takotsubo syndrome (TS) has not been described. We report on a 37-year-old woman presenting with a clinical picture of acute coronary syndrome 1 day after initiation of treatment with bromocriptine for ablactation 3 weeks after a ...
Fu Yi - - 2011
Background and Purpose: Vascular endothelial growth factor (VEGF) plays a key role in the development of cerebral infarction as a major mediator of angiogenesis. The aim of this study was to investigate whether the VEGF gene polymorphisms were associated with the risks of acute cerebral infarction. Methods: We examined the ...
Zhang Tong - - 2011
BACKGROUND: Post-stroke depression (PSD) is a common consequence of stroke that negatively interferes with the rehabilitation outcome in patients. It remains unclear what relationship exists between the site and size of brain infarcts and the development of PSD and the risk factors for PSD. We conducted a MRI-based cohort study ...
Ng Ramford - - 2011
Cardiogenic shock is often a devastating consequence of acute myocardial infarction (MI) and portends to significant mortality and morbidity. Despite improvements in expediting the time to treatment and enhancements in available medical therapy and reperfusion techniques, cardiogenic shock remains the most common cause of mortality following MI. Post-MI cardiogenic shock ...
Singh Neha - - 2011
Chemokines regulates the trafficking of leukocytes to the site of inflammation hence may be implicated in cardiac events. Currently no consistent effects have been revealed their role in acute myocardial infarction (MI). The aim of current study was to investigate the impact of human chemokine receptor genetic variants, CCR5-Δ32 insertion/deletion, ...
Bang Oh Young - - 2011
BACKGROUND AND PURPOSE: Collaterals sustain the ischemic penumbra to limit growth of the infarct core before revascularization, yet the impact of baseline collateral flow on hemorrhagic transformation (HT) after endovascular therapy remains unknown. METHODS: A collaborative study from 2 stroke centers in distinct geographic regions included 222 consecutive patients who ...
Ball Timothy - - 2011
Achieving a door-to-balloon time <90 min may be challenging in patients with ST-segment elevation acute myocardial infarction with difficult to wire coronary lesions. We report use of the Venture wire control catheter to facilitate wiring in four patients with significant tortuosity proximal to a thrombotic coronary occlusion, after conventional wiring ...
Falluji Nezar - - 2011
Stroke remains a major cause of morbidity and mortality worldwide. Despite preventive measures, effective management strategies are needed to reduce the morbidity and mortality associated with this devastating condition. While the management of hemorrhagic stroke is mostly limited to supportive care, reperfusion strategies in ischemic stroke have been developed and ...
Biswas Sinjini - - 2011
The practice of adjunctive balloon post-dilatation is not consistent among interventionalists, particularly in the setting of acute myocardial infarction (AMI). There have been some concerns about the risks of adjunctive balloon post-dilatation, particularly in the setting of acute coronary syndrome (ACS). This review will examine the data on the angiographic ...
White Christopher J - - 2011
The majority (>80%) of the three-quarters of a million strokes that will occur in the United States this year are ischemic in nature. The treatment of acute ischemic stroke is very similar to acute myocardial infarction, which requires timely reperfusion therapy for optimal results. The majority of patients with acute ...
Corrales-Medina Vicente F - - 2011
Despite the availability of excellent antibiotics, the mortality from community-acquired pneumonia (CAP) remains substantial. Most deaths occur during the first week of hospitalization. Because antibiotics rapidly eradicate bacteria from pulmonary secretions, an ongoing inflammatory response may be responsible for the poor outcome, and treatment with immunomodulatory drugs might be beneficial ...
Mise Naobumi - - 2011
We report the case of a 53-year-old hemodialysis patient with severe aortic stenosis, who developed acute systemic hypoperfusion after arteriovenous fistula (AVF) construction. He presented with hypotension and repeated syncope soon after distal radiocephalic AVF construction, and finally developed a respiratory arrest. His blood pressure and hemodynamics recovered promptly by ...
Freixa Xavier - - 2011
INTRODUCTION: Endothelin-1 (ET-1), circulating endothelial cells (CEC) and endothelial progenitor cells (EPC) are well-known modulators of endothelial function with important cardiac effects after an acute myocardial infarction. However, the relationship between them has never been assessed. The objective of the present study was to establish the relationship between ET-1, CEC, ...
Brinks Henriette - - 2011
Morbidity and mortality of myocardial infarction remains significant with resulting left ventricular function presenting as a major determinant of clinical outcome. Protecting the myocardium against ischemia reperfusion injury has become a major therapeutic goal and the identification of key signaling pathways has paved the way for various interventions, but until ...
Jose John - - 2011
Despite diagnostic and therapeutic advances, mortality and morbidity associated with infective endocarditis (IE) remains high. Congestive heart failure and complications such as septic embolization and aortic root abscess are the main causes. Although aortic root abscess is a common complication of IE involving the aortic valve, acute myocardial infarction (AMI) ...
Gadaleta Francisco - - 2011
Over many decades, the corrected QT (QTc) has become an established clinical tool for the prediction of sudden cardiac death and life-threatening ventricular arrhythmias and for monitoring adverse effects of pharmacological agents capable of triggering serious ventricular arrhythmias mainly associated with QTc prolongation. Recent evidence also suggests that QTc prolongation ...
Bruintjes Gerrit - - 2011
Smoking ordinances have been associated with reduced acute myocardial infarction rates, but nearly all studies lack patient-level data. We determined whether a smoking ordinance was associated with a reduction in hospitalizations for acute myocardial infarction, irrespective of smoking status and infarct presentation (ST elevation vs. non-ST elevation). Detailed chart abstraction ...
Nakbi Amel - - 2011
Background: Cardiovascular disease is the consequence of appearance and development of atherosclerosis lesions of associated with a inflammatory complication. Aim: To elucidate a possible association between several inflammation and oxidative stress markers according to the severity of coronary artery disease. Methods: This study was carried on 93 coronary subjects with: ...
Lo Rito Mauro - - 2011
Infective endocarditis in patients with ventricular septal defects can prove life threatening due to acute heart failure or septic embolization. Persistent postoperative risk is bacterial colonization of prosthetic material. We designed the Antibiotic Sandwich Patch to reduce this risk, using a double layer of autologous pericardium containing antibiotic powder. Five ...
Choi Daniel C - - 2011
The Impella 5.0 microaxial pump is a miniaturized left ventricular assist device commonly used for circulatory support in acute cardiogenic shock. The catheter-based pump is designed to be inserted either into a peripheral artery or directly into the ascending aorta. We report the first case in which the Impella 5.0 ...
Flaherty Michael P - - 2011
This report describes a case of an acute anterior myocardial infarction secondary to subacute stent thrombosis of a drug-eluting stent within the proximal segment of the left anterior descending artery (LAD) 5 days after percutaneous transluminal coronary angioplasty and stenting (PCI). The patient was initially managed with conventional dual-antiplatelet therapy ...
Upadhyay Shailendra - - 2011
Proximal right coronary artery occlusion caused transient loss of sensing and capture of the atrial lead of a permanent dual-chamber pacemaker. Forty-five days after percutaneous revascularization, the atrial lead was discovered to be functioning normally. We hypothesize that ischemia of the right atrium caused stunning of the atrial myocardium at ...
Smedema Jan-Peter - - 2011
This report describes the findings and management of a young male who presented with an acute ST-segment elevation myocardial infarction due to compression of the circumflex coronary artery by a large aneurysm of left sinus of Valsalva.
Pant Sadip - - 2011
Ischemic mitral regurgitation is a frequent complication of acute coronary syndrome. It primarily occurs in patients with a prior myocardial infarction but also may be seen with acute ischemia, a setting in which the MR typically resolves after the ischemia resolves. The vast majority of patients have "functional" ischemic MR. ...
Barreto Andrew D - - 2011
For many decades, intravenous (IV) thrombolytics have been delivered to treat acute thrombosis. Although these medications were originally effective for coronary thrombosis, their mechanisms have proven beneficial for many other disease processes, including ischemic stroke. Treatment paradigms for acute ischemic stroke have largely followed those of cardiology. Specifically, the aim ...
Shah Nikunj R - - 2011
We report the case of an acute proximal occlusion of the left anterior descending (LAD) coronary artery, possibly due to exercise-induced dissection, in a previously well 43-year-old man with persistently normal electrocardiograms (ECG) and cardiac enzymes throughout his hospitalisation. In LAD lesions, ECG repolarisation abnormalities usually reflect the underlying acute ...
Ziakas Antonios G - - 2011
Levels of inflammatory markers increase in patients with acute coronary syndromes (ACS) and the magnitude of the inflammatory response has been related to clinical outcomes. The release patterns and, thereby, the time point of maximal increase for multiple inflammatory markers following an ACS are not fully defined. Our purpose was ...
Ivanes Fabrice - - 2011
Background Recent studies have demonstrated that aldosterone levels measured in patients with heart failure or acute myocardial infarction (MI) are associated with long-term mortality, but the association with aldosterone levels in patients with coronary artery disease (CAD) outside these specific settings remains unknown. In addition, no clear mechanism has been ...
Linfante Italo - - 2011
BACKGROUND AND PURPOSE: Vessel recanalization is a strong predictor of good outcome in acute ischemic strokes (AIS) secondary to large vessel occlusions. We report our single-center experience with self-expandable stents in the treatment of AIS. METHODS: The stroke database of Baptist Cardiac and Vascular Institute in Miami was retrospectively reviewed ...
Kambouri Katerina - - 2011
Primary omental infarction (POI) has a low incidence worldwide, with most cases occurring in adults. This condition is rarely considered in the differential diagnosis of acute abdominal pain in childhood. Herein, we present a case of omental infarction in an obese 10-year-old boy who presented with acute abdominal pain in ...
Stegemann Berthold - - 2011
Aims Cardiac resynchronization therapy (CRT) by means of biventricular pacing (BiVP) is well established as a treatment for patients with heart failure (HF). Post-extrasystolic potentiation, (PESP) which involves a transient increase in myocardial contractility following a ventricular extrasystole, can be achieved using extrasystolic stimulation (ESS). On this basis, ESS has ...
Clever Yvonne P - - 2011
Background-Optimal reperfusion strategy in ST-elevation myocardial infarction is controversial. Failure of fibrinolytic therapy is related to limited efficacy, high reocclusion rates, reinfarction, and systemic bleeding complications. Data on the impact of percutaneous coronary intervention (PCI) after fibrinolysis are conflicting. The Southwest German Interventional Study in Acute Myocardial Infarction (SIAM III) ...
Gowala Harsh - - 2011
We hereby report a short case of 71-year-old gentleman who developed ST segment elevation myocardial infarction shortly after starting the infusion of liposomal amphotericin B for disseminated histoplasmosis. We also discuss the novel pathogenesis of specific liposomal component of amphotericin B that contributed to the acute cardiopulmonary compromise in our ...
Peace Aaron - - 2011
An interesting case of acute coronary syndrome occurring shortly after a cardiac catheterization is reported. Different tests and imaging modalities for coronary artery disease have been performed in this patient. The potential for integration of the information available is underscored in order to overcome their inherent limitations.
Speranza Lorenza - - 2011
AIM: Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide (NO) which plays an important role in controlling vascular tone and regulates the contractile properties of cardiac myocytes. The aim of this study was to investigate the effect of pharmacological treatment on symmetric dimethylarginine (SDMA), ADMA and arginine plasma ...
Hoeper Marius M - - 2011
Despite advances in medical therapies, pulmonary arterial hypertension (PAH), continues to cause significant morbidity and mortality. Although the right ventricle can adapt to an increase in afterload, progression of the pulmonary vasculopathy that characterizes PAH causes many patients to develop progressive right ventricular failure. Furthermore acute right ventricular decompensation may ...
Pleister Adam P - - 2011
Nesiritide, a synthetic drug form of human B-type natriuretic peptide, is approved for the early treatment of dyspnea in acute decompensated heart failure. Meta-analyses suggested a risk of worsening renal insufficiency and mortality with its use. Therefore, the Acute Study of Clinical Effectiveness in Decompensated Heart Failure (ASCEND-HF) was designed ...
Riesgo Alba - - 2011
The atypical characteristics of acute coronary syndrome in women lead to differences in management and treatment. We investigated these differences in the urgent management of non-ST-segment acute myocardial infarction (NSTEMI). Data on 39 variables were collected from 539 patients with NSTEMI treated at 97 Spanish emergency departments. After adjustment for ...
Micheli Sara - - 2011
In patients admitted for acute stroke, the clinical burden of acute myocardial infarction (AMI) and acute heart failure (AHF) is unclear. In these patients we evaluated: (1) the prevalence of AMI and AHF; (2) the effect of AMI and/or AHF on mortality at 3 months; (3) the risk factors for AMI ...
Nilssen Camilla - - 2011
We report a case of ventricular perforation by an active-fixation permanent pacemaker lead in a young woman with congenital heart defect and pacemaker because of atrioventricular block. The rarity of the case is based not only upon the late perforation (as opposed to the more common acute perforations) but also ...
Mirzaii-Dizgah Iraj - - 2011
Myocardial infarction (MI) is the main cause of death all over the world. Biomarkers of cardiac necrosis are of great importance in the diagnosis of MI. The aim of this study was to determine probable changes of creatine kinase MB isoform (CK-MB) levels in saliva of patients with acute MI. ...
Yanavitski Marat - - 2011
Heart failure goes beyond mechanical dysfunction and involves an interplay of multiple pathophysiologic mechanisms, including inflammation, tissue remodeling, neurohormonal and endocrine signaling, and interactions with the renal and nervous systems. This article highlights some novel biomarkers that may aid in diagnosis, treatment, and prognosis of acute heart failure, specifically focusing ...
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