Search Results
Results 351 - 400 of 5149
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Erdogan Dogan - - 2012
BACKGROUND: Uric acid (UA) is an independent marker of mortality and associated with increased oxidative stress in patients with congestive heart failure (CHF). The present study aimed to investigate the effect of allopurinol on left ventricular (LV) function and coronary microvascular integrity in patients with idiopathic dilated cardiomyopathy (IDC). METHODS: ...
Abate Elena - - 2012
Identification of patients with reversible left ventricular (LV) dysfunction has important prognostic implications after acute myocardial infarction (AMI). This study aimed to determine the value of LV segmental and global longitudinal strains assessed with 3-dimensional (3D) speckle-tracking analysis in predicting improvement of LV function after AMI. One hundred fifty-three patients ...
Olson Jens - - 2012
OBJECTIVES: To investigate the value of tissue Doppler imaging (TDI) measurements of right ventricular (RV) systolic and diastolic function as a predictor of long term cardiovascular outcomes in patients with left ventricular (LV) systolic heart failure. BACKGROUND: In patients with LV systolic heart failure, RV function has been shown to ...
Lee Seung-Pyo - - 2012
AIMS: Apical hypertrophic cardiomyopathy (ApHCM) is a subtype of hypertrophic cardiomyopathy, which is clinically suspected by a characteristic giant negative T (GNT) wave on electrocardiogram (ECG) and diagnosed by demonstrating apical hypertrophy on ECG. However, GNT may not always be specific for ApHCM as in this report of apically displaced ...
Inami Takumi - - 2012
AIMS: Many patients with idiopathic dilated cardiomyopathy (DCM) have been diagnosed on the basis of the exclusion of significant coronary stenosis and the presence of left ventricular (LV) dysfunction. In the present study, we investigated the possibility that coronary multispasm is one of the mechanisms leading to diffuse idiopathic DCM-like ...
Kawasaki Tatsuya - - 2012
Objectives: Limited data are available regarding Holter monitoring for cardiovascular events except for ventricular tachycardia as a risk marker for sudden death in hypertrophic cardiomyopathy (HCM). We aimed to examine Holter findings in relation to the long-term prognosis in patients with HCM. Methods: Ambulatory Holter monitoring was performed in 106 ...
Subherwal Sumeet - - 2012
The impact of polyvascular disease (peripheral arterial disease [PAD] and cerebrovascular disease [CVD]) on long-term cardiovascular outcomes among older patients with acute myocardial infarction has not been well studied. Patients with non-ST-segment-elevation myocardial infarction aged ≥65 years from the CRUSADE (Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse ...
Talatinian Alidz - - 2012
Despite numerous pharmacologic and nonpharmacologic treatment strategies, heart failure remains a complex, progressive disorder with significant morbidity and mortality. Angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), and β-blockers have been used as routine treatment options for heart failure for the majority of patients with left ventricular systolic dysfunction ...
Nozue Tsuyoshi - - 2012
SUMMARY AT A GLANCE: This study examined the impact of kidney dysfunction on coronary atherosclerosis by evaluating coronary atherosclerosis using the intrasvascular ultrasound (IVUS) with virtual histology before and after statin. The authors showed that decreased GFR is associated with expanded remodeling and a greater atheroma volume, particularly the fibro-fatty ...
Imasaka Ken-Ichi - - 2012
OBJECTIVE: The optimal timing of mitral valve surgery for severe mitral regurgitation is controversial. We aimed to evaluate the changes in left ventricular performance using ventricular energetics and left ventricular mass regression after the surgery to determine the appropriate surgical timing in asymptomatic patients with severe mitral regurgitation. METHODS: Fifty ...
Lee Richard - - 2012
OBJECTIVE: Early readmission in patients hospitalized for medical congestive heart failure is common, expensive, and associated with a worse late survival. Our objective was to compare late survival in patients' readmission for congestive heart failure with readmission for other causes in patients undergoing cardiac surgery. METHODS: Of 3654 consecutive patients ...
La Meir Mark - - 2012
OBJECTIVE: The present study was aimed at demonstrating the beneficial effect of minimally invasive radiofrequency surgical ablation on left atrial remodeling using 2-dimensional speckle-tracking echocardiography. METHODS: The study population consisted of 33 patients (mean age, 64.6 ± 6.9 years; 84.8% men) with paroxysmal lone atrial fibrillation undergoing minimally invasive radiofrequency ...
Nai Fovino Luca - - 2012
PURPOSE: The aim of the study was to assess the role of myocardial perfusion scintigraphy (MPS) in the prediction of future cardiac events in elderly hypertensive patients and to investigate if its prognostic value is maintained during a 10-year follow-up period. METHODS: A total of 229 consecutive patients ≥ 65 ...
Borghi Claudio - - 2012
BACKGROUND: Angiotensin-converting enzyme inhibitors (ACEIs) are largely employed for treating patients with left ventricular dysfunction (LVD), but their efficacy may be negatively affected by concomitant administration of acetylsalicylic acid (ASA), with some difference among the different compounds. HYPOTHESIS: The interaction between ASA and the two ACEIs zofenopril and ramipril may ...
Shah Rachit M - - 2012
BACKGROUND: The role of vasodilator therapy in asymptomatic patients with chronic moderate to severe aortic regurgitation (AR) and normal left ventricular (LV) function is uncertain. We assessed the effects of vasodilator therapy (hydralazine, calcium channel blockers, and angiotensin-converting enzyme inhibitors) in this subgroup of patient population. HYPOTHESIS: Vasodilators have favorable ...
Sang Song Pil - - 2012
BACKGROUND: We examined the impact of non-ST-segment elevation acute coronary syndrome (NSTE-ACS) on clinical outcomes in patients with bifurcation lesions treated with drug-eluting stents. HYPOTHESIS: We hypothesized that NSTE-ACS would be attributable to the increased risk of major adverse cardiac events (MACE) in bifurcation percutaneous coronary intervention. METHODS: We enrolled ...
Silva Margarida - - 2012
INTRODUCTION: Viral myocarditis can lead to heart failure that is refractory to medication. In these cases, a ventricular assist device is a good therapeutic option that can be used as a bridge to transplantation or recovery. We describe the first case in Portugal of recovery with ventricular assistance after severe ...
Aljaroudi Wael - - 2012
PURPOSE: LV mechanical dyssynchrony (LVMD) is a risk marker in narrow QRS cardiomyopathy, but its association with treatment outcome is not well defined. We determined the incremental prognostic value of LVMD in ischemic cardiomyopathy, and assessed its interaction with scar, myocardium in jeopardy and subsequent revascularization. METHODS: Stress and rest ...
Andersen Mads J - - 2012
BACKGROUND: -Left Ventricular (LV) diastolic dysfunction is common after myocardial infarction (MI) despite preservation of LV ejection fraction (LVEF), yet it remains unclear how or whether diastolic dysfunction affects cardiac hemodynamics with stress. METHODS AND RESULTS: -Invasive hemodynamic exercise testing was performed in 46 patients with a recent MI and ...
Kreuz Jens - - 2012
BACKGROUND: A growing number of patients with advanced heart failure fulfill a primary-prevention indication for an implantable cardioverter-defibrillator (ICD). This study seeks to identify new predictors of overall mortality in a Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT)-like collective to enhance risk stratification. HYPOTHESIS: An impaired renal function and ...
Fang Fang - - 2012
BACKGROUND: Coronary blood flow (CBF) is improved by cardiac resynchronization therapy (CRT) and impaired by right ventricular apical (RVA) pacing in patients with heart failure. However, the underlying mechanism remains unclear. METHODS: Twenty-nine non-ischemic heart failure patients who responded to CRT underwent transthoracic echocardiography examination including both left anterior descending ...
Stähli Barbara E - - 2012
INTRODUCTION: Left ventricular non-compaction cardiomyopathy (LVNC) is a rare cardiomyopathy, originally described as an isolated disease without other structural cardiac abnormalities. The aim of this study was to explore the prevalence of LVNC among adults with different types of congenital heart disease. METHODS: From our databases we identified adults with ...
Bordier Philippe - - 2012
Cardiac pacing is ineffective in obstructive sleep apnea (SA), but it can alleviate central SA/Cheyne-Stokes respiration (CSA) in patients with heart failure (HF). We examined whether overnight overdrive ventricular pacing (OVP) has an effect on SA in pacemaker recipients with permanent atrial fibrillation (AF). An apnea-hypopnea index (AHI) ≥ 15 ...
Fan Jinqi - - 2012
BACKGROUND: Whether ZES can further improve angiographic and clinical outcomes compared to SES still remains uncertain. OBJECTIVES: The aim of this study was to assess the efficacy and safety of zotarolimus-eluting stents (ZES) compared with sirolimus-eluting stents (SES) in patients undergoing percutaneous coronary interventions (PCI). METHODS: Major electronic information sources ...
Schreiber Donald H - - 2012
OBJECTIVES: We evaluated a third-generation high sensitivity "guidelines acceptable" troponin I assay (hs-cTnI) against a contemporary "clinically usable" troponin assay (cTnI). DESIGN AND METHODS: Remnant samples of undifferentiated Emergency Department (ED) patients with suspected acute coronary syndrome were enrolled. Baseline and 90-minute samples were analyzed for cTnI and hs-cTnI. Sensitivity, ...
Kiani Abdolrazagh - - 2012
Load independent methods should be used for the assessment of ventricular function. Debate still exists regarding whether tissue Doppler imaging (TDI) indices are influenced by preload. Here, we evaluated the effect of positive end expiratory pressure (PEEP) related preload reduction on both conventional pulsed Doppler (PD) and TDI myocardial performance ...
Schulmeyer M C C - - 2012
BACKGROUND: The index E/e' derived from tissue Doppler imaging and pulsed Doppler is the ratio of the early transmitral flow velocity and the early mitral annular velocity and it correlates with left ventricular filling pressure. The purpose of this study was to investigate the relationship between intraoperative E/e' and postoperative ...
Hanna Elias B - - 2012
The characteristics, therapies, and outcomes of patients presenting with non-ST-segment elevation myocardial infarction, found to have significant coronary artery disease on coronary angiography, and managed without revascularization ("nonrevascularized patients") have not been evaluated previously in a large-scale registry. We examined data on 13,872 non-ST-segment elevation myocardial infarction nonrevascularized patients who ...
Stavrakis Stavros - - 2012
AIMS: Atrioventricular junction (AVJ) ablation with permanent pacing improves symptoms in selected patients with atrial fibrillation (AF). The optimal pacing modality after AVJ ablation remains unclear. We performed a meta-analysis of randomized controlled trials to examine whether cardiac resynchronization therapy (CRT) is superior to right ventricular (RV) pacing in this ...
Hall S G - - 2012
Cardiac power output has been shown to quantify cardiac reserve. Cardiac reserve is defined as the difference between basal and maximal cardiac performance. We compared cardiac power index to other commonly used hemodynamic parameters to validate its usefulness to stage heart failure patients and determine the optimal time for implantation ...
Nozue Tsuyoshi - - 2012
Background: Patients with diabetes mellitus (DM) have a markedly increased incidence of adverse cardiovascular events, but the mechanisms have not been well-characterized. Methods and Results: The TRUTH study evaluated the effects of 8-month statin therapy on coronary artery plaque composition using virtual histology intravascular ultrasound (IVUS). Analyzable IVUS data were obtained from ...
Thuny Franck - - 2012
This study aimed to determine whether post-conditioning at the time of percutaneous coronary intervention could reduce reperfusion-induced myocardial edema in patients with acute ST-segment elevation myocardial infarction (STEMI). Myocardial edema is a reperfusion injury with potentially severe consequences. Post-conditioning is a cardioprotective therapy that reduces infarct size after reperfusion, but ...
Ito Toshiaki - - 2012
OBJECTIVES: Surgical results for post-infarction ventricular septal rupture (VSR) remain poor, even today. The aim of this study was the establishment and clinical evaluation of a simple, standardized septal patch technique for this disease. METHODS: From 1999 to 2011, 16 consecutive patients with a mean age of 73.1 ± 10.1 (range 55-89) ...
Lipska Kasia J - - 2012
BACKGROUND: <0.0001). Greater GV was associated with higher mortality for all metrics (eg, mortality was 3.8%, 5.5%, 7.1%, and 11.3% for increasing quartiles of range, P<0.0001); however, the association between GV and mortality for each metric was no longer significant after multivariable adjustment. In contrast, mean BG remained an important ...
Lønborg Jacob Thomsen - - 2012
AIMS: The left atrium (LA) transfers blood to the left ventricle in a complex manner. LA function is characterized by passive emptying (LA passive fraction), active emptying (LA ejection fraction), and total emptying (LA fractional change). Despite this complexity, the clinical relevance of the LA is based almost exclusively on ...
Loos Caroline M J CM Department of Neurology, Maastricht University Medical Centre and Cardiovascular Research Institute Maastricht, University Maastricht, The Netherlands. - - 2012
Studies in patients with lacunar stroke often assess the number of lacunes. However, data on how many symptomatic lacunar infarcts cavitate into a lacune are limited. We assessed the evolution of symptomatic lacunar infarcts over 2-year follow-up. In 82 patients with first-ever lacunar stroke with a lacunar infarct in the ...
Eggermont Laura H P - - 2012
Cognitive impairment in cardiac patients may interfere with disease management. This review describes studies examining specific cognitive impairments in cardiac patients and studies that investigate the link between echocardiographic and cognitive measures. Executive function impairments were frequently reported in different patient groups. Also, lower cardiac output and worse left ventricular ...
Harb Serge C - - 2012
Although exercise echocardiography (ExE) of asymptomatic patients early (2 years after percutaneous coronary intervention [PCI] or 5 years after coronary bypass graft surgery [CABG]) after revascularization is considered inappropriate, the appropriateness of later testing is indeterminate. Treatment responses to positive test results in either setting have uncertain outcome implications. We ...
Ang Donald S C - - 2012
The role of high sensitivity troponin T (hs-TnT) in the convalescence phase after an acute coronary syndrome (ACS) is unknown. The authors aim to assess the prognostic utility of a single hs-TnT level at 7-week post-ACS. Second, the authors evaluated whether any serial changes in hs-TnT between the index admission ...
Jin Han-Young - - 2012
BACKGROUND: Recent studies have shown that post-clopidogrel high platelet reactivity (HPR), assessed by a point-of-care assay, is associated with a higher risk of adverse events after percutaneous coronary intervention (PCI). We assessed the clinical impact of HPR by the VerifyNow P2Y12 point-of-care assay in 181 patients with ST-segment elevation myocardial ...
Olimulder Marlon A G M - - 2012
Knowledge about potential differences in infarct tissue characteristics between patients with prior life-threatening ventricular arrhythmia versus patients receiving prophylactic implantable cardioverter-defibrillator (ICD) might help to improve the current risk stratification in myocardial infarction (MI) patients who are considered for ICD implantation. In a consecutive series of (ICD) recipients for primary ...
Mohindra Sandeep - - 2012
Symptomatic, paradoxical intracranial tuberculomas is a rare occurrence. A case of tubercular meningitis, developing paradoxical tuberculomas alongside non-functional ventricular catheter is presented. Catheter removal facilitated removal of these paradoxical lesions, with the patient recovering to near-normal state after completing 12 months of anti-tubeculous therapy. Non-functional ventricular catheter may become the ...
Fiabane Elena - - 2012
PURPOSE: Few studies have analyzed the relationship between job satisfaction and return to work (RTW) in cardiac patients. The aim of this paper was to investigate whether job satisfaction predicted early RTW in patients sick listed after cardiac invasive procedures. METHODS: A 6-month prospective study was carried out in a ...
Monto Fermi - - 2012
Down-regulation of β(1)-ARs and increased expression/function of GRK2 have been observed in human heart failure, but changes in the expression of other ARs and GRKs have not yet been established. Another unresolved question is the incidence of these compensatory mechanisms in accordance with heart failure etiology and treatment. To analyze ...
Pulido Juan N JN Department of Anesthesiology, Division of Critical Care Medicine, Mayo Clinic, Rochester, MN 55905, USA. - - 2012
To determine the frequency and spectrum of myocardial dysfunction in patients with severe sepsis and septic shock using transthoracic echocardiography and to evaluate the impact of the myocardial dysfunction types on mortality. A prospective study of 106 patients with severe sepsis or septic shock was conducted from August 1, 2007, ...
Chen Zhen - - 2012
BACKGROUND: The ability of microvolt T-wave alternans (MTWA) for risk stratification of cardiac events in patients with ischemic cardiomyopathy (ICM) has not been well established. METHODS: The authors systematically reviewed current literature and carried out a meta-analysis to determine the ability of MTWA to predict the outcome severity after ICM. ...
Milani Rodrigo Mussi - - 2012
BACKGROUND: In general, surgeries currently tend to be less invasive and cardiac surgery has started to follow this trend. OBJECTIVE:To evaluate the evolution of one hundred patients undergoing minimally-invasive coronary artery bypass grafting. METHODS: Access to the heart was attained through a small; 6-cm thoracotomy, located in the 4th left ...
Renilla Alfredo - - 2012
Aim:  Elderly patients often remain underrepresented in clinical trials. The aim of our study was to analyze the treatment, clinical outcome and risk factors for mortality in patients aged ≥85 years with ST-segment elevation myocardial infarction (STEMI). Methods:  From 2005-2011, 102 patients aged ≥85 years with STEMI admitted to a coronary care ...
Sönmez Osman - - 2012
OBJECTIVE: We aimed to evaluate effect of termination property of left anterior descending (LAD) on tissue Doppler echocardiography (TDE) parameters in patients experiencing their first anterior myocardial infarction (AMI) who had undergone successful primary percutaneous coronary intervention (PCI). METHODS: A prospective, cross-sectional observational study was performed. Eighty-four patients were enrolled ...
Cioffi Giovanni - - 2012
Background and Aims: In patients with chronic pressure overload due to hypertension or aortic valve stenosis (AS), higher left atrial systolic force (LASF) is associated with a high-risk cardiovascular (CV) phenotype. We tested LASF as prognostic marker in patients with AS. Methods: We used baseline and outcome data from 1,566 ...
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