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Results 401 - 450 of 1697
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Thiele Holger - - 2007
Cardiogenic shock (CS) remains the most common cause of death in patients with acute myocardial infarction (AMI). In addition to percutaneous coronary intervention, inotropes, and fluids, intraaortic balloon pumping (IABP) is most widely used for initial haemodynamic stabilization. However, the main limitation of IABP is the lack of active circulatory ...
Rosamel P - - 2007
BACKGROUND AND OBJECTIVES: The death of patients treated by ventricular assist device is usually related to multiorgan failure for which a disorder of splanchnic circulation is blamed. Gastric tonometry (measurement of gastric intra-mucosal pressure of CO(2)) has already been studied in many fields and especially in cardiac surgery. The aim ...
Selzman Craig H - - 2007
Several strategies for circulatory support have been successfully utilized as bridges to recovery or transplantation after acute myocardial infarction and cardiogenic shock. We report the novel use of a continuous flow left ventricular assist device (LVAD) for successful recovery and bridging to transplantation in a patient who had massive anterior ...
Drakos Stavros G - - 2007
A significant proportion of patients placed on long-term mechanical circulatory support for end-stage heart failure can be weaned from mechanical assistance after functional recovery of their native heart ("bridge to recovery"). The pathophysiological mechanisms implicated in reverse remodeling that cause a sustained functional myocardial recovery have recently become the subject ...
Slaughter Mark S - - 2007
BACKGROUND: As outcomes for destination therapy continue to improve, many patients are requiring left ventricular assist device (LVAD) exchange due to end-of-life of their LVAD. Current techniques to identify and diagnose device end-of-life issues usually require invasive testing or off-site filter dust analysis. In this study we assess a non-invasive ...
Slaughter Mark S - - 2007
OBJECTIVE: The Thoratec Implantable Ventricular Assist Device (Thoratec Corporation, Pleasanton, Calif) can be used for univentricular or biventricular support in patients with a body surface area as low as 1.3 m(2). Results of the multicenter clinical trial are reviewed. METHODS: Between October 2001 and June 2004, a total of 39 ...
Lee W Anthony - - 2007
Endovascular repair of abdominal aortic aneurysms has become part of the standard of care for those patients with appropriate anatomy. Since its initial reporting in 1991, numerous devices have been manufactured and undergone various stages of clinical trials and subsequent postmarket use. Currently, there are four commercially available devices. Without ...
Delgado Diego H - - 2007
Left ventricular assist devices (LVADs) are an important adjunct to the management of end-stage heart failure patients. Uncertainty remains regarding whether to remove an LVAD in a clinically stable, asymptomatic patient who displays signs of ventricular recovery. To evaluate, from a patient's perspective, the quality-adjusted life expectancy of an LVAD ...
Maybaum Simon - - 2007
BACKGROUND: Myocardial recovery after left ventricular assist device (LVAD) support has been reported. The LVAD Working Group Recovery Study was a prospective multicenter trial to assess the incidence of myocardial recovery in patients bridged to cardiac transplantation. METHODS AND RESULTS: After LVAD implantation, patients were evaluated with the use of ...
Chandra Divay - - 2007
The TandemHeart percutaneous left ventricular assist device is a left atrial-to-femoral artery bypass system that can be implanted percutaneously within 30 minutes and provides active circulatory support. The TandemHeart has been used mainly for temporary hemodynamic assistance during high-risk coronary interventions and postcardiotomy heart failure. This report describes initial experience ...
Garatti Andrea - - 2007
Cardiogenic shock (CS) occurs in 7% to 10% of cases after acute myocardial infarction and remains the most common cause of death in these patients. Despite aggressive treatment regimens such as fibrinolysis and percutaneous transluminal coronary angioplasty, mortality rates from CS remain extremely high. It has been shown that intra-aortic ...
Tuzun Egemen - - 2007
We evaluated the effects of the Levitronix UltraMag pediatric ventricular assist system on healthy animals during 29- to 90-day periods by assessing hemocompatibility and hepatic and renal functions while operating the device in a flow range suitable for pediatric patients. Nine lambs (weight, 15 to 24 kg) received the Levitronix ...
Haft Jonathan W - - 2007
Predicting end-of-life for left ventricular assist devices is important to determine timing of device removal. A retrospective analysis was performed on 46 patients undergoing implantation of the latest HeartMate XVE from July 1, 2003, through March 31, 2006. Devices were assessed by analysis of motor current waveforms and quantification of ...
Farrar David J - - 2007
A long-term left ventricular assist system for permanent use in advanced heart failure is being developed on the basis of a compact centrifugal pump with a magnetically levitated rotor and single-fault-tolerant electronics. Key features include its "bearingless" (magnetic levitation) design, textured surfaces similar to the HeartMate XVE left ventricular assist ...
Drakos Stavros G - - 2007
The role of ventricular-assist devices in the management of end-stage heart failure is growing. Initially developed as a 'bridge to transplantation', they are now implanted permanently in patients who need cardiac replacement but are not candidates for cardiac transplantation ('destination therapy'). Furthermore, observations from expert centers indicate that a significant ...
Mortensen Kai - - 2007
With increasing advances in technology, cardiac pacemakers have become highly sophisticated devices that allow diagnostic and therapeutic functions beyond conventional antibradycardic therapy. This review discusses the most promising developments in antibradycardic device therapy, such as novel diagnostic functions, telemonitoring, autoadjustment of programmed parameters, algorithms for support of intrinsic atrioventricular conduction, ...
Klotz Stefan - - 2007
Mechanical support is often the only therapeutic option in low cardiac output (LCO) following cardiac operation using extracorporeal circulation (ECC). However, the question whether primary ventricular assist device (VAD) or primary extracorporeal membrane oxygenation (ECMO) followed by secondary VAD implantation is superior remains unclear. We analyzed the outcome of 183 ...
Sclafani Anthony P - - 2007
Periorbital rejuvenation can enhance a patient's appearance, with changes of only a few millimeters making a significant impact. Many patients undergoing blepharoplasty often have mild brow or midfacial changes for which they are unwilling to undergo additional concurrent forehead or midface procedures, however, because these procedures may be associated with ...
Lauten Alexander - - 2007
We report a case of a patient suffering from massive myocardial infarction after traumatic dissection of the left coronary system. The dissection involved the left coronary artery including peripheral segments of the coronary circulation. The patient was revascularized; however, she could not be weaned from cardiopulmonary bypass thereafter. An Impella ...
Mellinger John D - - 2007
BACKGROUND: Current developments in intraluminal and transluminal natural orifice surgery are limited by issues of access, tissue manipulation, and secure tissue approximation/closure. This report describes an initial laboratory experience with a novel tissue approximation and suturing device. The device is deployed via a previously described platform and is 6 mm ...
Catena E - - 2007
Mechanical circulatory support is, nowadays, a well established treatment modality for end stage heart failure. Patients candidate for cardiac transplantation who decompensate while awaiting graft can be supported by long-term left ventricular assist devices (long-term LVAD). These devices are intracorporeal pumps, expensive and complicated to install, but offer the advantages ...
Whitson Bryan A - - 2007
A patient with multisystem organ failure and refractory cardiopulmonary shock stemming from Aspergillus pneumonia was treated with 2 Levitronix ventricular assist devices as a bridge-to-recovery. After ventricular assist device placement, the patient recovered myocardial function. The ventricular assist devices were removed on post-implant Day 7, and the patient made a ...
Bhargava Kartikeya - - 2007
Lead dislodgement and migration is a known complication after implantation of cardiac rhythm devices. We present a case of dislodgement of atrial lead of the CRT-D system and its migration into the device pocket. The device itself had rotated by 90 degrees but the right and left ventricular leads were ...
Ibrahim Moheb - - 2007
BACKGROUND: Early graft failure is associated with high mortality and is the main cause of death within the first 30 days after transplantation. The purpose of the present study was to examine the investigators' experience of severe perioperative acute graft failure and to review the literature. METHODS: Nine of 385 ...
SzymaƄski Piotr - - 2007
A case of an echocardiographic diagnosis of biventricular assist device inflow cannula obstruction, associated with low cardiac output in a 29-years old male with dilated cardiomyopathy and severe congestive heart failure is presented. The reasons for low cardiac output in patients supported with ventricular assist devices and the role of ...
Moreira Luiz Felipe P - - 2007
This study was performed to assess the safety and feasibility of the implantation of ventricular assist devices (VADs) as a bridge to heart transplantation in patients with advanced biventricular failure due to Chagas' disease. Six patients were submitted to paracorporeal left VAD implantation, while right ventricular dysfunction was managed clinically. ...
Matthews Jennifer Cowger - - 2007
An increasing number of patients have a coexisting implantable cardioverter defibrillator (ICD) and left ventricular assist device (LVAD) to treat ventricular arrhythmias and refractory heart failure, respectively. To date, there have been no published reports of negative interactions between these devices that have impacted appropriate ICD or LVAD function. In ...
Tozzi Piergiorgio - - 2007
The off-pump trans left ventricular approach provides an alternative option for insertion of stented aortic valves of any size for endovascular replacement. One of the key steps in this procedure is the repair of the ventricle after catheter withdrawal. This study evaluates the reliability of a new device for sutureless ...
Small Roy S - - 2007
Heart failure is a difficult and costly disease to manage in part because the symptoms may be protean, the physical findings obscure, and the laboratory assessments unreliable. New implanted physiologic monitors may simplify the care of patients with heart failure, if they can be incorporated into routine clinical practice. Cardiac ...
Klotz Stefan - - 2007
OBJECTIVES: We hypothesized that angiotensin-converting enzyme inhibition (ACE-I) during left ventricular assist device (LVAD) support in patients with end-stage heart failure prevents potentially deleterious effects on the extracellular matrix. BACKGROUND: Left ventricular assist device-induced mechanical unloading increases myocardial collagen and stiffness and may contribute to the low rate of recovery. ...
Bedi Maninder - - 2007
Left ventricular assist devices (LVADs) have been used effectively as a "bridge" to cardiac transplantation and as destination therapy in patients with advanced heart failure. Ventricular arrhythmias (VAs) have been reported to occur in LVAD-supported patients, although their incidence, risk factors, and clinical significance have not been characterized. In this ...
Mather Paul J - - 2007
Heart failure is the only cardiovascular disease diagnosis increasing in prevalence in the United States. A number of drugs have been shown to reduce morbidity and mortality in patients with chronic heart failure. Despite these advances, the frequency of hospitalization for heart failure has continued to increase, and clinical trial ...
Ji Bingyang - - 2007
Although heart-lung machines and cardiac assist devices have been used successfully for acute and chronic cardiac support for decades, controversies still remain concerning the benefits of pulsatile and non-pulsatile perfusion. The core of the debate is whether enough energy is generated by the artificial pulse to keep capillary beds open ...
Cournoyer Kenneth - - 2007
Heart disease kills as many people as nearly all other causes of death combined. Chronic, progressive, end-stage heart failure results in substantial health care costs and immeasurable suffering for both individuals in particular and society in general. Ventricular assist devices are having an increasing role in supporting patients with severe ...
Masuoka Ayumu - - 2007
In Japan, no mechanical circulatory support is available for children. We report a case of terminal stage cardiac failure in a 16-kg girl who was implanted with an adult-sized Toyobo-NCVC left ventricular assist device (Toyobo-National Cardiovascular Center, Osaka, Japan) in our unit. She successfully underwent heart transplantation in the United ...
Zimpfer Daniel - - 2007
OBJECTIVE: Fixed pulmonary hypertension is a contraindication for cardiac transplantation because of the increased risk of donor heart failure. We sought to determine whether left ventricular assist devices improve fixed pulmonary hypertension in cardiac transplant candidates to enable safe cardiac transplantation. METHODS: Thirty-five consecutive cardiac transplant candidates (age 56 +/- ...
Chu Michael W A - - 2007
We report the implantation of a Berlin Heart ventricular assist device (VAD) in a 4-year-old boy with hypoplastic left heart syndrome previously palliated with Norwood and Glenn operations, who presented with progressive ventricular failure and hypoxemia. Insertion of a 30-mL pneumatic pediatric pump with cannulation of the systemic right ventricle ...
Ramcharitar Steve - - 2007
The TandemHeart left ventricular assist device was used to support the haemodynamics in a case of high risk percutaneous coronary intervention where surgery was not considered to be the first line therapeutic option. The patient had poor left ventricular function with a Logistic Euroscore of 11.4%. Highlighted in this report ...
De Luca Giuseppe - - 2007
BACKGROUND: The benefits of adjunctive mechanical devices to prevent distal embolization in patients with acute myocardial infarction (AMI) are still a matter of debate. The aim of this meta-analysis was to combine data from all randomized trials conducted with adjunctive mechanical devices to prevent distal embolization in AMI. METHODS: The ...
Gojo Satoshi - - 2007
We describe a novel therapy of mononuclear cell transplantation combined with a left ventricular assist device (LVAD) for severe ischemic heart failure. Significant myocardial recovery by the LVAD rarely occurs in the severely failing heart. We undertook successful mononuclear cell transplantation in a patient who sustained an acute myocardial infarction ...
Jorgensen Jesse - - 2007
Percutaneous delivery of left atrial appendage (LAA) occluding devices represents a novel approach for stroke prevention in patients with atrial fibrillation. Transesophageal echocardiography (TEE) has a pivotal role throughout these procedures, facilitating device size selection and ensuring optimal deployment of the device. We report a case of an LAA occluding ...
Jahanyar Jama - - 2007
The formation of pump thrombus after implantation of axial-flow ventricular assist devices has been described previously. We report a case of recurrent pump thrombus formation in a 63-year-old man who was bridged to heart transplantation with a MicroMed DeBakey ventricular assist device. He was treated with a low, dose-adjusted thrombolytic ...
Fynn-Thompson Francis - - 2007
Ventricular assist device therapy is continuing to evolve in the practice of pediatric cardiac surgery. Although ECMO is still the most often applied mechanical support for infants and young children, a broader range of pulsatile, paracorporeal, as well as implantable ventricular assist devices are now available for pediatric application. A ...
Sachweh Jörg S - - 2007
BACKGROUND: To report our experience with extracorporeal membrane oxygenation (ECMO) in a congenital heart surgery program. METHODS: Since 12/1996, 24 patients (8 newborns, 9 infants, 3 children, 4 adolescents/ adults 17-23 years), mean age 4.0+/-7.4 years (2 days-23 years), body weight 2.7-87 kg had ECMO as circulatory support. Indication was ...
Tatsumi Eisuke - - 2007
A series of guidelines for development and assessment of next-generation medical devices has been drafted under an interagency collaborative project by the Ministry of Health, Labor and Welfare and the Ministry of Economy, Trade and Industry. The working group for assessment guidelines of next-generation artificial hearts reviewed the trend in ...
Clegg Andrew J - - 2007
OBJECTIVES: The clinical and cost-effectiveness of left ventricular assist devices as destination therapy for people with end-stage heart failure is assessed through a systematic review and economic evaluation. METHODS: Systematic review was performed of randomized controlled trials, quasiexperimental studies, case series, and case studies identified through searching eighteen electronic databases, ...
Sjauw Krischan D - - 2007
Since its first clinical application in patients with cardiogenic shock (CS) in 1968, the intra aortic balloon pump (IABP) increasingly has been used for several clinical conditions requiring mechanical cardiac assistance. In current practice, IABP therapy is still the most accessible and most frequently used method of mechanical cardiac assistance. ...
George Robert S - - 2007
After Mustard or Senning procedures, transplantation remains the only option for some patients who present at late stage with severe systemic (right) ventricular failure. In some circumstances these patients may require urgent mechanical circulatory support to bridge them to transplantation. The use of mechanical support poses considerable potential and actual ...
Saito Shunsuke - - 2007
We report three consecutive cases of long-term circulatory support using the HeartMate vented electric (VE) left ventricular assist system (LVAS). The HeartMate VE LVAS dramatically improved the functional status and quality of life of these three patients with end-stage heart failure, and all were successfully bridged to transplantation after 659, ...
Lee Chi-Hang - - 2007
BACKGROUND: Clinical studies have evaluated the safety and efficacy of adjunctive X-sizer (EndiCOR Inc, San Clemente, CA) in percutaneous coronary intervention (PCI). However, patient and lesion subsets were highly selected, and extrapolation of the results to daily practice is problematic. METHODS: X-sizer thrombectomy was performed in 200 procedures from August ...
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