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Evlakhov V I VI Department of Physiology of Visceral Systems, Research Institute of Experimental Medicine, Northwestern Division of the Russian Academy of Medical Sciences, St. Petersburg, - - 2014
The responses of cardiovascular parameters to left-ventricular myocardial ischemia induced under control conditions and after administration of nitroglycerin or acetylcholine were examined in rabbits. In nitroglycerine-treated rabbits, experimental myocardial ischemia produced less pronounced depressor BP shifts in the pulmonary artery than those produced by ischemia in controls (prior to pharmacological ...
McMahon Colin J CJ Department of Pediatric Cardiology, Our Lady's Children's Hospital, Crumlin, Dublin, Ireland. Electronic address: - - 2014
A newborn baby girl was diagnosed with tricuspid atresia, ventricular septal defect, normally related great vessels, and hypoplastic right ventricle with no pulmonary stenosis. There was extensive left ventricular noncompaction cardiomyopathy. The left ventricular ejection fraction was 58%. She underwent placement of a pulmonary arterial band at 4 weeks of ...
Piotrowicz Ewa E Telecardiology Center, Institute of Cardiology, Warsaw, Poland. Electronic address: - - 2014
Percutaneous pulmonary valve implantation (PPVI) is an alternative to open-heart surgery in patients with congenital heart defect. The purpose of the study is to evaluate right ventricle (RV) electrocardiographic characteristics in relation with hemodynamic changes after PPVI. In 30 patients (16 males, aged 24±7years), ECG RV characteristics changes (R amplitude ...
Güvenç Tolga Sinan TS Department of Cardiology, School of Medicine, Kafkas University, Kars, - - 2014
Degree of increase in pulmonary artery pressure (PAP) and adaptive responses in right ventricular morphology and mechanics play an important role in the prognosis of chronic obstructive pulmonary disease (COPD) patients. Three dimensional echocardiography and deformation imaging are recent advancements in echocardiography that allow more through assessment of right ventricle. ...
Durmus E E Faculty of Medicine, Department of Cardiology, Marmara University, Fevzi Cakmak Mahallesi, Mimar Sinan Caddesi, No: 41 Ustkaynarca, Pendik, Istanbul, - - 2014
Systemic sclerosis (SSc) is a systemic connective tissue disease and cardiac involvement is one of the most important causes of death. Right ventricular (RV) systolic dysfunction is a poor prognostic finding in SSc patients. Assessment of RV function has some difficulties because of its crescent shape and extensive trabeculations. Two-dimensional ...
Liu Christopher F CF Division of Cardiology, Weill Cornell Medical College, New York, NY - - 2014
-Idiopathic ventricular arrhythmias of left bundle branch block, inferior axis morphology are usually localized to the right ventricular outflow tract (RVOT), presumably below the pulmonic valve (PV). However, the PV location is usually not confirmed by direct visualization. -Intracardiac echocardiography (ICE) was used to visualize and tag the PV annulus, ...
Thum Thomas T Institute of Molecular and Translational Therapeutic Strategies (IMTTS) and Integrated Research and Treatment Center Transplantation (IFB-Tx), Hannover Medical School, Hannover, Germany ; Excellence Cluster REBIRTH, Hannover Medical School, Hannover, Germany; and National Heart and Lung Institute, Imperial College London, London, United - - 2014
MicroRNAs (miRNAs) are molecules increasingly investigated for both diagnostic and therapeutic strategies. Whereas information about their role in the left ventricle has been studied for many years, there is scarce information about the right ventricle. We thus here review known details about the expression, regulation, and function of miRNAs in ...
Buckberg Gerald G Department of Cardiothoracic Surgery, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, Calif. Electronic address: - - 2014
The right ventricle (RV) is composed of a free wall containing a wrap-around circumferential muscle at its base and a septum composed of helical fibers that are oblique and cross each other at 60° angles. This structure is defined by the helical ventricular myocardial band and defines RV function because ...
Chik William W B WW Cardiology Department, Westmead Public and Private Hospitals, Sydney, Australia; Sydney Medical School, University of Sydney, Sydney, - - 2014
Organized atrial tachycardias (OATs) after pulmonary vein isolation (PVI) procedure are common. Arrhythmia mechanisms include mitral annular, ring gap, or roof-dependent gap-related flutters. In this series, we describe a mechanism of arrhythmia utilizing the ridge between left pulmonary vein (PV) and left atrial appendage (LAA) in the Ligament of Marshall ...
Ventetuolo Corey E CE Rhode Island Hospital, Pulmonary and Critical Care Medicine, Providence, Rhode Island, United States ; - - 2014
Right ventricular failure occurs when the right ventricle fails to maintain enough blood flow through the pulmonary circulation to achieve adequate left ventricular filling. This can occur suddenly in a previously healthy heart due to massive pulmonary embolism or right sided myocardial infarction, but many cases encountered in the intensive ...
Konecny Tomas T Departments of Cardiovascular Diseases and Pulmonary and Critical Care, Mayo Clinic, Rochester, Minnesota; Department of Cardiology and Internal Medicine, International Clinical Research Center-St Anne's Hospital, Brno, Czech - - 2014
Chronic obstructive pulmonary disease (COPD) is associated with increased cardiovascular morbidity and mortality, yet the exact pathophysiological links remain unclear. Whether the presence and severity of COPD are associated with atrial or ventricular arrhythmias recorded on continuous electrocardiographic monitoring is unknown. We identified consecutive adult patients who underwent clinically indicated ...
Chatterjee Neal A NA Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, - - 2014
This study examined the prognostic significance of pre- and post-capillary components of pulmonary hypertension (PH) in patients receiving cardiac resynchronization therapy (CRT). PH is common in patients with left ventricular systolic dysfunction (LVSD) receiving CRT. The impact of PH subtype on clinical outcome in CRT is unknown. The study population ...
Fontoura Dulce D Department of Physiology and Cardiothoracic Surgery, Faculty of Medicine, University of Porto, Porto, - - 2014
Endothelin-1 antagonists are increasingly used in the treatment of pulmonary hypertension despite the lack of knowledge of their myocardial and systemic effects. We assessed the right ventricular myocardial and systemic effects of endothelin-1 antagonists in monocrotaline-induced pulmonary hypertension. Male Wistar rats (180-200 g, n=57) randomly received 60 mg/kg monocrotaline or ...
Li Shu-Juan SJ Division of Paediatric Cardiology, Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, The University of Hong Kong, 102, Pokfulam Road, Hong Kong, - - 2014
This study sought to explore right (RV) and left ventricular (LV) mechanics and ventricular-ventricular interaction in adolescents and young adults late after percutaneous balloon pulmonary valvoplasty (PBPV) for valvar pulmonary stenosis (PS). Potential late effects of PS despite PBPV on cardiac mechanics have not been well defined. Thirty-one patients aged ...
Zhan Zhong-Qun ZQ Department of Cardiology, Shiyan Taihe Hospital, Hubei University of Medicine, Shiyan City, Hubei Province, - - 2014
We have previously described new electrocardiogram (ECG) findings for massive pulmonary embolism, namely ST-segment elevation in lead aVR with ST-segment depression in leads I and V4 -V6 . However, the ECG patterns of patients with acute pulmonary embolism during hemodynamic instability are not fully described. We compared the differences between ...
Ozyilmaz Isa I Department of Pediatric Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Center and Research Hospital, Istanbul, Turkey. Electronic address: - - 2014
Patients who have pulmonary atresia with intact ventricular septum have been shown to have a number of various myocardium anomalies like ischemia, fibrosis, infarction, rupture, disarray, spongious myocardium and ventricular endocardial fibroelastosis. Multiple connections have been found between right ventricular myocardial sinusoids and small branches of intramural coronary arteries. Noncompation ...
Lundgren Jakob J The Haemodynamics Lab, Clinic for Heart Failure and Valvular Disease, Skåne University Hospital, Lund, Sweden; Department of Cardiology, Clinical Sciences, Lund University, Lund, - - 2014
Pulmonary hypertension (PH) due to left heart failure is becoming increasingly prevalent, and is associated with poor outcome. The precise pathophysiological mechanisms behind PH due to left heart failure are, however, still unclear. In its early course, PH is caused by elevated left ventricular filling pressures, without pulmonary vessel abnormalities. ...
Hamdan Righab R Cardiology Department, Beirut Cardiac Institute, Beirut, - - 2014
Right ventricular (RV) function immediately after left ventricular assist device (LVAD) implantation is a crucial prognostic factor. RV failure is linked to increased mortality and worse outcome. A phosphodiesterase 5 inhibitor, sildenafil, was shown to decrease pulmonary vascular resistance and pulmonary artery pressure post-LVAD. We report on a series of ...
Kaya Zeynettin Z Department of Cardiology, Konya Numune State Hospital, Konya, - - 2014
Negative pressure pulmonary edema (NPPE) is defined as fluid transudation into the pulmonary interstitium which occurs as a result of elevated negative intrathoracic pressure caused by the upper respiratory tract obstruction and strong inspiratory effort. NPPE is usually seen during emergence from general anesthesia in the early post-operative period especially ...
Spethmann Sebastian - - 2014
Subclinical myocardial involvement is common in systemic sclerosis (SSc) and associated with poor prognosis. Early detection, particularly during follow-up, is important. Two-dimensional speckle tracking echocardiography (STE) has already been shown to detect early left ventricular systolic impairment in SSc patients with advanced disease. The aim of this study was to ...
Yang Tao T From the State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of - - 2014
It is known that patients with pulmonary hypertension (PH) can have elevated F-FDG uptake in the right ventricle (RV) on PET imaging. This study was designed to assess possible relationship between FDG uptake of ventricles and the function/hemodynamics of the RV in patients with PH. Thirty-eight patients with PH underwent ...
Felkai Alena A Petersham, New South Wales, - - 2014
Cardiomyopathies have been reported in many primates. They may result from an inflammatory response to an infectious agent, nutritional deficiency, familial-genetic inheritance or toxic agents, but in many cases they are idiopathic. A De Brazza's monkey (Cercopithecus neglectus) presented with weight loss and inappetence. Physical examination, blood collection and diagnostic ...
Rath Werner H WH Faculty of Medicine, Gynecology and Obstetrics, University Hospital RWTH Aachen, Department of Anesthesiology, University of Heidelberg, Institute of Forensic Medicine, LMU - - 2014
Amniotic fluid embolism (AFE) is a life-threatening obstetric complication that arises in 2 to 8 of every 100 000 deliveries. With a mortality of 11% to 44%, it is among the leading direct causes of maternal death. This entity is an interdisciplinary challenge because of its presentation with sudden cardiac ...
Dengate A A North Shore Veterinary Specialist Centre, Crows Nest, NSW, 2065, - - 2014
A 13-year-old neutered male Maltese was referred for paroxysms of coughing and cyanosis, with radiographic evidence of bronchial disease and cardiomegaly. Investigation with echocardiography, bronchoscopy, fluoroscopy and bronchoalveolar lavage led to a diagnosis of myxomatous mitral valve degeneration with insufficiency, ISACHC class II heart failure and bronchomalacia with severe left ...
Haeck Marlieke L A ML Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The - - 2014
Pulmonary hypertension has been associated with right ventricular (RV) dyssynchrony which may induce left ventricular (LV) dysfunction and dyssynchrony through ventricular interdependence. The present study evaluated the influence of RV dyssynchrony on LV performance in patients with pulmonary hypertension. One hundred and seven patients with pulmonary hypertension (age 63 ± 14 years, systolic ...
Jenab Yaser - - 2014
Patients with acute pulmonary thromboembolism (PTE) and right ventricular (RV) dysfunction may benefit from thrombolytic therapy. We sought to determine the usefulness of RV strain imaging in the demonstration of improvement in RV function in response to thrombolytic therapy. This study prospectively enrolled 32 consecutive patients who received thrombolytic therapy ...
Seitz Julien J From the Hôpital Saint Joseph, 26 Bd de Louvain, 13008 Marseille, France. Electronic address: - - 2014
The role of pulmonary veins (PVs) in persistent atrial fibrillation (AF) perpetuation appears less important than in paroxysmal AF. Electrogram-based Substrate ablation is not widely performed as a stand-alone strategy OBJECTIVE: We sought to evaluate PV activity in AF perpetuation and efficacy of our patient-tailored ablation strategy (Electrogram-based Substrate ablation ...
Mahadavan Gnanadevan G The Queen Elizabeth Hospital, Department of Cardiology, Basil Hetzel Institute, The University of Adelaide, - - 2014
To evaluate new development in the utility of brain natriuretic peptide and N-Terminal brain natriuretic peptide (BNP/NT-Pro-BNP) in the management of various cardiovascular diseases. The determination of plasma BNP levels has an established role in the discrimination of pulmonary oedema from other causes of acute dyspnoea, and there is increasing ...
Nie Xin X Department of Respiratory Medicine, Shanxi Medical University Affiliated People's Hospital of Shanxi Province, Taiyuan, Shanxi 030012, - - 2014
Phosphatase and tensin homologue on chromosome ten (PTEN) acts as a convergent nodal signalling point for cardiomyocyte hypertrophy, growth and survival. However, the role of PTEN in cardiac conditions such as right ventricular hypertrophy caused by chronic hypoxic pulmonary, hypertension remains unclear. This study preliminarily discussed the role of PTEN ...
Bugan B B Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH, USA. - - 2014
Pulmonary hypertension (PH) is a chronic, progressive debilitating disease and associated with poor prognosis despite the novel numerous treatment options. Beta-blockers constitute a cornerstone in left heart failure treatment; however, we still don't know the role of beta-blokers on PH and they are considered relatively contraindicated in patients with PH ...
Aronson Doron D Department of Cardiology, Rambam Medical Center, Haifa, - - 2014
Sleep disordered breathing (SDB), characterized by nightly intermittent hypoxia, is associated with multiple pathophysiologic alterations that may adversely affect patients with acute myocardial infarction (AMI). This prospective study investigated whether the metabolic perturbations associated with SDB are present when these patients develop AMI and if they affect clinical outcomes. We ...
Weber Cristina K CK Instituto de Cardiologia, Fundação Universitária de Cardiologia do Rio Grande do Sul, Porto Alegre, RS, - - 2014
Proper assessment of dyspnea is important in patients with heart failure. Our aim was to evaluate the use of the 5-point Likert scale for dyspnea to assess the degree of pulmonary congestion and to determine the prognostic value of this scale for predicting adverse events in heart failure outpatients. We ...
Chalikias George - - 2014
Pulmonary embolism (PE) is a common and potentially life threatening disease if left untreated. This is due to a natural tendency towards early recurrence of pulmonary emboli which may lead to right ventricular failure. Thus, anticoagulant treatment should be administered to all patients upon high or intermediate clinical probability of ...
Waleed Mohammad M Department of Cardiology, Castle Hill Hospital, East Yorkshire, - - 2014
A 67-year-old woman presented to the accident and emergency department with central chest pain for the past 4 months. She described the pain as severe, retrosternal, intermittent, indigestion/burning type, with radiations to the left arm. She had used antacids with no relief. Her medical history included hypertension, chronic obstructive pulmonary disease, ...
Jain Sachin Kumar Amruthlal SK Department of Cardiology, Providence Hospital and Medical Center, 16001 W Nine Mile Road, Southfield, MI 48075, - - 2014
Acute pulmonary embolism (PE) can be devastating. It is classified into three categories based on clinical scenario, elevated biomarkers, radiographic or echocardiographic features of right ventricular strain, and hemodynamic instability. Submassive PE is diagnosed when a patient has elevated biomarkers, CT-scan, or echocardiogram showing right ventricular strain and no signs ...
Si Ming-Sing - - 2013
Hypoplastic left heart syndrome, the most common complex congenital heart malformation, is characterized by underdeveloped left-sided heart structures. The Norwood procedure followed by two-staged operations has permitted the extended survival of many of these patients. Survival, however, remains suboptimal with most of the morbidity and mortality occurring during the Norwood ...
Neilan Tomas G - - 2013
We tested whether myocardial extracellular volume (ECV) is increased in patients with hypertension and atrial fibrillation (AF) undergoing pulmonary vein isolation and whether there is an association between ECV and post-procedural recurrence of AF. Hypertension is associated with myocardial fibrosis, an increase in ECV, and AF. Data linking these findings ...
Zhong-Qun Zhan - - 2013
Acute pulmonary embolism (APE) is often misdiagnosed as acute coronary syndrome because of the similarity of the presenting symptoms and of the electrocardiogram (ECG) manifestations. In APE, ST-segment elevation (STE) in leads V1 to V3 /V4 , mimicking anteroseptal myocardial infarction, is not a rare phenomenon. Negative T waves (NTW) ...
Pardos-Gea José - - 2013
Non-valvular cardiac disease in the antiphospholipid syndrome (APS) has been scanty studied. We wanted to assess the prevalence and evolution of left myocardial disease, pulmonary hypertension and intracardiac thrombi in a cohort of APS patients. A total of 53 patients with APS, either primary (n = 34, 64%) or associated ...
Lin J - - 2013
We present the case of a patient who developed new-onset asymptomatic sinus tachycardia after undergoing treatment for a right ventricular myocardial infarction. Even after excluding heart failure, infection and bleeding, the sinus tachycardia persisted. Computed tomography pulmonary angiography showed multiple bilateral pulmonary emboli. The vital sign abnormality resolved after treatment ...
Villafañe Juan - - 2013
Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart defect. We explore "Hot Topics" to highlight areas of emerging science for clinicians and scientists in moving towards a better understanding of long-term management in patients with repaired TOF. From a genetic perspective, the etiology of TOF is multifactorial, ...
Dresden Scott - - 2013
The objective of this study was to determine the diagnostic performance of right ventricular dilatation identified by emergency physicians on bedside echocardiography in patients with a suspected or confirmed pulmonary embolism. The secondary objective included an exploratory analysis of the predictive value of a subgroup of findings associated with advanced ...
Zaragoza-Macias Elisa - - 2013
With surgical repair most children with Tetralogy of Fallot survive into adulthood. The main complications seen after Tetralogy of Fallot repair include arrhythmias, sudden cardiac death, pulmonary regurgitation, and right ventricular dysfunction/heart failure. Pulmonary regurgitation over time may lead to right ventricular dilation and failure. In this article, we will ...
Platz Elke - - 2013
Lung ultrasound (LUS) represents a novel, noninvasive method in the assessment of extravascular lung water. We investigated the utility of LUS in ambulatory subjects with dyspnea or prior heart failure (HF). We studied 81 ambulatory subjects with HF history or dyspnea who underwent transthoracic echocardiography (TTE) with LUS of 8 ...
Hart Stephen A - - 2013
Tetralogy of Fallot (TOF) repair and pulmonary valvotomy for pulmonary stenosis (PS) lead to progressive pulmonary insufficiency (PI), right ventricular enlargement and dysfunction. This study assessed whether pulmonary regurgitant fraction measured by cardiovascular magnetic resonance (CMR) could be reduced with inhaled nitric oxide (iNO). Patients with at least moderate PI ...
Rodrigues Ana Clara Tude - - 2013
To assess prognosis of pulmonary thromboembolism using tissue Doppler echocardiography and brain natriuretic peptide. Patients aged over 18 years were evaluated within 24 hours of confirmed diagnosis (chest tomography/pulmonary scintigraphy) of pulmonary embolism using two-dimensional echocardiography and tissue Doppler for right ventricular systolic (s') velocities, strain, tissue tracking and myocardial ...
Lazović Biljana - - 2013
Rapidly vanishing lung pseudotumor (phantom tumor) refers to the transient well-demarcated accumulation of pleural fluid in the interlobar pulmonary fissures. Most frequently their appearance is associated with congestive heart failure, but also other disorders like hypoalbuminemia, renal insufficiency or pleuritis. Its rapid disappearance in response to the treatment of the ...
Bessa Luiz Gustavo Pignataro - - 2013
Pulmonary arterial hypertension is a severe and progressive disease. Its early diagnosis is the greatest clinical challenge. To evaluate the presence and extension of the delayed myocardial contrast-enhanced cardiovascular magnetic resonance, as well as to verify if the percentage of the myocardial fibrosis mass is a severity predictor. Cross-sectional study ...
Nguyen Tin T Tin Nguyen, Long-Bao Cao, Minh Tran, Assad Movahed, Department of Cardiovascular Sciences, East Carolina University, Brody School of Medicine, East Carolina Heart Institute, Greenville, NC 27834, United - - 2013
Pulsus alternans is characterized by regular rhythm with beat-to-beat alternation of systolic pressures. Left ventricular alternans is usually found in severe left ventricular dysfunction due to cardiomyopathy, coronary artery disease, systemic hypertension, and aortic stenosis. Right ventricular alternans is usually associated with left ventricular alternans, right ventricular dysfunction, pulmonary embolism, ...
Calcutteea Avin - - 2013
Pulmonary hypertension (PH) is known to affect the right ventricular (RV) function. To assess the extent of global and regional RV dysfunction in PH patients. We performed a cross-sectional study on 20 controls (age 62 ± 15 years, 7 males) and 35 patients (age 67 ± 12 years, 13 males) with PH of mixed etiologies and ...
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