Search Results
Results 201 - 250 of 1419
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Karfis E A - - 2008
AIM: Patients with depressed left ventricular function are more susceptible to develop postoperative complications after cardiac surgery. The aim of the present study was to examine the effect of severe left ventricular dysfunction on the activation of systemic inflammatory reaction during and after coronary artery bypass grafting (CABG). METHODS: Clinical ...
Yuan Xin - - 2008
BACKGROUND: This research was aimed at validating a new risk model for in-hospital mortality in Chinese patients undergoing coronary artery bypass graft (CABG) surgery. This model (NYS), which was developed for isolated CABG surgery from data of New York's cardiac surgery reporting system in 2002, was proved effective, but its ...
Mukamal Kenneth J - - 2009
Although inflammatory markers and anemia have both been associated with prognosis in patients with cardiovascular disease, their relation with atherosclerotic progression in patients with previous coronary artery bypass grafting (CABG) is unknown. A total of 1,273 patients enrolled in the Post CABG Trial who had undergone CABG 1 to 11 ...
Pegg Tammy J - - 2008
BACKGROUND: Beating heart coronary artery bypass grafting (CABG) improves early postoperative cardiac function in patients with normal ventricular function, but its effect in patients with impaired function is uncertain. We compared a novel hybrid technique of on-pump beating heart CABG (ONBEAT) with conventional on-pump CABG (ONSTOP) in patients with impaired ...
Levine Stewart - - 2008
Perioperative graft failure remains a significant problem and carries a very high morbidity and mortality in patients undergoing coronary artery bypass grafting (CABG). Different therapeutic options are available for the clinician to manage this complication. These include direct reoperation, balloon angioplasty, angioplasty along with stenting, intra-aortic balloon pumping, and conservative ...
Rossi Daniel - - 2008
Coronary artery bypass graft (CABG) surgery is performed 350,000 times annually in the United States, making it one of the most commonly performed major operations. A 1-2% stroke rate, which includes spinal artery infarct, is associated with CABG primarily in the elderly population (1). Spinal cord infarction is infrequent, but ...
El Diasty Mohammad - - 2009
OBJECTIVES: The aim of this study is to review the outcome of OP-CABG using bilateral internal thoracic artery (BITA) grafts in these patients in terms of morbidity and mortality. Patients and method: Retrospective data from consecutive 64 octogenarian patients who underwent this surgery in the period between April 1998 and ...
Becker Richard C - - 2009
Coronary arterial bypass grafting (CABG)-the most common heart surgery performed worldwide-is an effective procedure for treating patients with advanced, obstructive atherothrombotic coronary artery disease, prolonging survival in selected high-risk patients. However, CABG is also associated with hemorrhagic complications, which can impact outcome measures such as perioperative morbidity, mortality, length of ...
Koonce Jay - - 2009
To investigate incidental extra-cardiac findings (ECF) at cardiac CT based on indication and impact on patient management. We retrospectively reviewed the reports of 1,764 patients who underwent a cardiac CT study between January 1, 2004 and December 31, 2006, including 463 calcium scorings (CS), 737 coronary CT angiograms (CTA), 341 ...
Loponen Pertti - - 2009
OBJECTIVE: Patients who undergo successful revascularisation either with coronary artery bypass grafting (CABG) or with percutaneous coronary intervention (PCI) may subsequently require repeat invasive procedures. METHODS: A cohort of 662 coronary artery diseased (CAD) patients was retrospectively reviewed. Follow-up was 36 months. RESULTS: Thirty-day mortality was 1.0% in the CABG ...
Kulik Alexander - - 2008
BACKGROUND: The benefits of statins have been demonstrated for patients with a remote history of coronary artery bypass grafting (CABG); however, no investigation to date has evaluated whether initiation of statin therapy in the early months after surgery improves clinical outcomes. METHODS AND RESULTS: A retrospective cohort of 7503 Medicare ...
de la Cruz Kim I - - 2008
In patients with coronary artery disease, the need for more accurately defined treatment recommendations based on the distribution of atherosclerotic disease has given rise to multiple trials designed to evaluate the efficacy of medical therapy versus percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG). To clarify these treatment ...
Benedetto Umberto - - 2008
BACKGROUND: Angiotensin-converting enzyme (ACE) inhibitors confer renal protection in different clinical settings. No final conclusions are available on the renal benefits of ACE inhibitors after coronary artery bypass grafting (CABG). Because ACE inhibitors decrease glomerular perfusion pressure, they may exacerbate kidney injury during cardiopulmonary bypass (CPB)-related hypoperfusion. We evaluated the ...
Diller Gerhard-Paul - - 2008
OBJECTIVE: Coronary artery bypass graft (CABG) surgery may induce myocardial stunning and thereby affect cardiac function. We aimed to assess whether myocardial function is affected by CABG in patients with preserved preoperative systolic function. METHODS: Myocardial tissue peak velocities were recorded at the lateral and septal angle of the mitral ...
Bulcao Christian F - - 2008
BACKGROUND: Cardiopulmonary bypass (CPB) and cardioplegic arrest during cardiac surgery leads to desensitization of myocardial beta-adrenergic receptors (beta-ARs). Impaired signaling through this pathway can have a detrimental effect on ventricular function and increased need for inotropic support. The mechanism of myocardial beta-AR desensitization during cardiac surgery has not been defined. ...
Kapoor John R - - 2008
This study sought to systematically compare the effectiveness of percutaneous coronary intervention and coronary artery bypass surgery in patients with single-vessel disease of the proximal left anterior descending (LAD) coronary artery. It is uncertain whether percutaneous coronary interventions (PCI) or coronary artery bypass grafting (CABG) surgery provides better clinical outcomes ...
Poston Robert S - - 2008
Minimally invasive coronary artery bypass grafting (miniCABG) decreases in-hospital morbidity versus traditional sternotomy CABG. We performed a prospective cohort study (NCT00481806) to assess the impact of miniCABG on costs and metrics that influence quality of life after hospital discharge. One hundred consecutive miniCABG cases performed using internal mammary artery (IMA) ...
Li Zhongmin - - 2008
BACKGROUND: The impact of off-pump coronary artery bypass graft surgery (OPCAB) on operative mortality compared to conventional coronary artery bypass graft surgery (CABG) with cardiopulmonary bypass (CCB) has not been clarified. METHOD: Patient clinical characteristics were compared between OPCAB and CCB for isolated CABG surgeries in 2003 to 2005 using ...
Kimura Takeshi - - 2008
BACKGROUND: Observational registries comparing coronary artery bypass graft (CABG) surgery and percutaneous coronary intervention (PCI) have reported long-term survival results that are discordant with those of randomized trials. METHODS AND RESULTS: We conducted a multicenter study in Japan enrolling consecutive patients undergoing first CABG or PCI between January 2000 and ...
van Boven Wim-Jan P - - 2008
OBJECTIVE: Oxidative stress as a result of reperfusion injury is a known causative factor of cardiac muscle injury. In the peripheral blood as well in the coronary sinus, oxidative stress parameters and cardiac biomarkers were measured to investigate the different levels of oxidative stress during three different CABG techniques; MCABG ...
Kim John Hyung-Jun - - 2008
BACKGROUND: Short-term use of clopidogrel plus aspirin among patients with acute coronary syndrome reduces ischemic events, but concerns about coronary artery bypass graft (CABG) surgery-related bleeding limit its early use. METHODS: Using data from 4,794 consecutive CABG procedures in the Duke Databank for Cardiovascular Disease (January 1999 to December 2003), ...
Kofidis Theo - - 2009
In the present study we identify parameters which influence the incidence of myocardial infarction (MI), need for percutaneous coronary intervention (PCI), coronary artery bypass grafting (CABG) and cardiac mortality after minimal invasive coronary artery bypass grafting (MIDCABG). With a mean follow-up of 30+/-11.2 months, 390 patients were assessed with Wald ...
Leegaard Marit - - 2008
For patients 40 years and over, ischemic coronary heart diseases are the most common reasons for admittance in European and North American hospitals. Coronary artery bypass grafting (CABG) has proved to be the most effective treatment for ischemic coronary heart diseases when other treatments are ineffective. The aim of this ...
McCarthy Patrick M - - 2008
Occasionally, high-risk patients in the post-myocardial infarction (MI) period require surgical intervention for stabilization and/or revascularization. In a meta-analysis involving 3,088 patients with ischemic heart disease, revascularization was associated with nearly an 80% reduction in the risk of death. Coronary artery bypass graft (CABG) surgery is commonly performed in post-MI ...
Zheng Zhe - - 2009
OBJECTIVE: The European System for Cardiac Operative Risk Evaluation (EuroSCORE) model is a widely used risk prediction algorithm for cardiac surgery in China due to lack of a local model, although its validation has never been tested. The aim of this study was to assess the performance of the logistic ...
Prucz Roni B - - 2008
BACKGROUND: Coronary artery bypass grafting (CABG) is an effective treatment for ischemic cardiomyopathy. However, patients with ventricular enlargement are known to have inferior outcomes. We assessed whether surgical ventricular restoration (SVR) with CABG (SVR + CABG) leads to improved outcomes versus CABG alone for patients with ischemic cardiomyopathy and ventricular ...
Prucz Roni B - - 2008
BACKGROUND: Surgical management of functional mitral regurgitation (MR) in ischemic cardiomyopathy is controversial. Surgical ventricular restoration (SVR) decreases left ventricular volume and may improve MR severity. We assessed the impact of SVR on the degree of MR. METHODS: We retrospectively reviewed patients with ejection fractions (EF) < 0.35 who underwent ...
Lattouf Omar M - - 2008
BACKGROUND: Off-pump coronary artery bypass graft surgery (OPCABG) may be associated with reduced morbidity and in-hospital mortality. In this study, we report the influence of surgery type, number of grafts, and the Index of Completeness of Revascularization (ICOR), namely, the number of grafts/number diseased vessel systems, on long-term survival. METHODS: ...
von Kiedrowski Helge - - 2009
BACKGROUND: Contrast enhanced multi-slice computed tomography (MSCT) is the leading modality in non-invasive coronary angiography (CTA) today. We investigated MSCT based assessment of coronary artery bypass grafts (CABG) by analyzing assets and drawbacks of CTA in order to define demands on latest technology. METHODS: In a clinical setting 39 CABG ...
Klein Patrick - - 2008
A systematic review of the literature was performed to determine early and late mortality associated with left ventricular (LV) reconstruction surgery and to assess the influence of different surgical techniques, concomitant surgical procedures, clinical and hemodynamic parameters on mortality. The MEDLINE database (January 1980-January 2005) was searched and from the ...
Daemen Joost - - 2008
BACKGROUND: Randomized trials that studied clinical outcomes after percutaneous coronary intervention (PCI) with bare metal stenting versus coronary artery bypass grafting (CABG) are underpowered to properly assess safety end points like death, stroke, and myocardial infarction. Pooling data from randomized controlled trials increases the statistical power and allows better assessment ...
Zhang Wen-feng - - 2008
BACKGROUND: Acute renal failure following coronary artery bypass grafting (CABG) surgery is associated with high morbidity and mortality. Approximately half of all patients who develop acute kidney injury (AKI) subsequently develop acute renal failure (ARF). The purpose of the study was to compare early transient changes in renal function within ...
Ang Keng-Leong - - 2008
BACKGROUND: Studies of the transplantation of autologous bone marrow cells (BMCs) in patients with chronic ischemic heart disease have assessed effects on viable, peri-infarct tissue. We conducted a single-blinded, randomized, controlled study to investigate whether intramuscular or intracoronary administration of BMCs into nonviable scarred myocardium during CABG improves contractile function ...
Sun Xiumei - - 2008
OBJECTIVE: Postoperative vasoplegic syndrome (PVS) is a potentially lethal condition with increased mortality and other postoperative morbidities. Many previous studies have examined the outcomes associated with on-pump coronary artery bypass grafting (CABG) surgery, little is known about the incidence of PVS after off-pump CABG. METHODS: From November 21, 2005 to ...
Wee Christina C - - 2008
OBJECTIVES: This study examines whether obesity accelerates atherogenic progression or adverse outcomes after coronary artery bypass graft (CABG) surgery. BACKGROUND: Obesity is a major risk factor for developing coronary heart disease. Whether obesity accelerates disease progression after CABG is unclear. METHODS: We examined how body mass index (BMI) related to ...
Davoodi Saeed - - 2008
BACKGROUND: Survival benefit with intra-aortic balloon pump (IABP) insertion for coronary artery bypass grafting (CABG) patients with left ventricular dysfunction is controversial. The aim of this study was to assess the early results of CABG that predict 30-day mortality and prolonged length of hospital stay (LOS) after isolated CABG and ...
Mujanović Emir - - 2008
This study investigated outcomes in patients undergoing coronary artery bypass grafting (CABG) without cardiopulmonary bypass (CPB), who needed conversion to CPB. Between September, 1998 and September, 2003, 1000 CABG procedures were performed in a Cardiovascular Clinic, University Clinical Centre Tuzla. Multivessel CABG were selected arbitrarily for CABG without CPB (OPCAB) ...
Mack Michael J - - 2008
BACKGROUND: Randomized trials have compared coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI). However, results of these trials in select patients may not accurately reflect current clinical practice using drug-eluting stents (DES) and off-pump CABG. We undertook a prospective registry of coronary revascularization by CABG on-pump and off-pump, ...
Darwazah A K - - 2008
AIM: Left ventricular function is an independent predictor of operative mortality. The outcome of myocardial revascularization is greatly affected by the severity of impairment of cardiac function. The present study was undertaken to find the early and midterm mortality and morbidity among patients with different degrees of myocardial function undergoing ...
Myredal Anna - - 2008
INTRODUCTION: Ventricular arrhythmias are uncommon after coronary artery bypass grafting (CABG), but the incidence and mortality are high in certain subsets of patients during the early recovery after surgery. Elevated temporal lability of myocardial repolarization has been associated with sudden cardiac death. The aim of the current study was to ...
Barandon Laurent - - 2008
Left ventricle dysfunction and comorbidities are responsible for a large number of complications after CABG. OPCAB could be an interesting alternative for very high-risk patients. Patients were included if EuroSCORE >9, or with at least two of the following criteria, severe LV dysfunction, recent myocardial infarction (MI), terminal renal failure, ...
Van der Heyden J - - 2008
In the absence of randomized trials, the optimal management of patients who present with concomitant carotid and coronary artery disease remains an enduring controversy, with much of the debate revolving around whether staged or synchronous carotid endarterectomy (CEA) will reduce peri-operative morbidity and mortality after cardiac surgery. Although encouraging results ...
Khoynezhad Ali - - 2008
The pharmacology characteristics of dihydropyridine calcium channel blockers (CCB) make them an attractive antihypertensive medication for use in the perioperative setting of coronary artery bypass graft (CABG) surgery. They lack the negative inotropic, negative chronotropic, and negative bathmotropic effects of phenylalkylamine and benzothiazepine CCB that limit the use in patients ...
Viaro Fernanda - - 2008
BACKGROUND AND AIM: There were strong evidences that nitric oxide has capital importance in the progressive vasodilatation associated with varied circulatory shock forms, including systemic inflammatory response syndrome (SIRS), in patients undergoing cardiac surgeries for cardiopulmonary bypass (CPB). If CPB procedures, per se, are the inciting stimulus for inflammation, plasma ...
Totaro Pasquale - - 2008
Since its introduction into clinical practice, coronary artery bypass graft (CABG) has become the most popular cardiac surgery procedure and, despite the challenge of cardiology interventional revascularization, an average of 1000 procedures per 1 million inhabitants are performed in Western countries annually. In the last decade, due to significant improvements ...
Triggiani M - - 2008
Patients with end-stage ischemic cardiomyopathy (IHD) and left ventricular (LV) dilatation are increasingly treated by means of surgical ventricular restoration (SVR). In some patients, SVR can delay heart transplantation (HTX). We retrospectively analyzed our experience, trying to ascertain whether HTX after a failed SVR (fSVR) carried a greater mortality risk. ...
Rastan Ardawan Julian - - 2008
OBJECTIVES: To characterize the current patient population regarding extent and pattern of coronary artery disease (CAD) in a routine cardiac catheterization practice with special focus on de-novo three-vessel coronary artery and/or left main disease (3-VD/LM) during enrolment in the SYNTAX study (synergy between PCI with Taxus drug-eluting stent and cardiac ...
Timaran Carlos H - - 2008
The management of concurrent carotid and coronary artery disease is controversial. Although single-center observational studies have revealed acceptable outcomes of combined carotid endarterectomy (CEA) and coronary artery bypass grafting (CABG), community-based outcomes have been substantially inferior. Recently, carotid artery stenting (CAS) has been introduced for the management of high-risk patients ...
Lorentzen Anne-Grethe - - 2008
OBJECTIVE: It has been argued that venous oxygen saturation from a central venous catheter (ScvO(2)) could be an inexpensive alternative to mixed venous oxygen saturation (SvO(2)). The aim was to evaluate whether ScvO(2) measurements could replace SvO(2) readings after cardiac surgery and to analyze factors influencing any differences found. DESIGN: ...
O'Connor Gerald T - - 2008
OBJECTIVES: The goal of this study was to assess the concordance between the American College of Cardiology (ACC) and the American Heart Association (AHA) 2004 Guideline Update for Coronary Artery Bypass Graft Surgery and actual clinical practice. BACKGROUND: There is substantial geographic variability in the population-based rates of coronary artery ...
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