Search Results
Results 301 - 350 of 1827
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Kim Ki-Hyun - - 2007
Leucine-rich Repeat Containing protein 10 (LRRC10) has recently been identified as a cardiac-specific factor in mice. However, the function of this factor remains to be elucidated. In this study, we investigated the developmental roles of Lrrc10 using zebrafish as an animal model. Knockdown of Lrrc10 in zebrafish embryos (morphants) using ...
Massoure Pierre-Laurent - - 2007
Systemic venous abnormalities are common and in some cases may be associated with congenital heart defects. We report here a case of a 67-year-old woman with bilateral superior vena cava with interruption of the inferior vena cava with hemiazygous continuation in the context of left atrial isomerism. These abnormalities were ...
Sani Mahmoud U - - 2007
Echocardiography is a major mode of cardiovascular imaging with versatile applications. Modern two-dimensional echocordiographic techniques provide a comprehensive means for evaluating virtually all forms of congenital heart disease (CHD) found in both adults and children. CHD is an abnormality in cardiocirculatory structure or function that is present at birth, even ...
Yildirim Selman Vefa - - 2007
INTRODUCTION: The first step in diagnosing congenital cardiac malformations is to assess the arrangement of the atrial appendages. In patients with abnormal lateralization of the organs of the body, the arrangement of atrial appendages is neither normal, nor a mirror image of normal. There are 2 categories of abnormal arrangement ...
Bradley Kimberly R - - 2007
Atrial septal defects are a frequent finding in young persons with strokes. New research now suggests migraines with aura may also be associated with these types of cardiac defects and that surgical treatment may result in a decrease or resolution of migraines. This case emphasizes the importance of a thorough ...
Yap Sing-Chien - - 2008
Discussion exists whether discrete subaortic stenosis (DSS) is a congenital or acquired cardiac defect. Currently, it is regarded an "acquired" cardiac defect presumably secondary to altered flow patterns due to morphological abnormalities in the left ventricular outflow tract, as have been shown by some studies in the pediatric population. In ...
Costache Victor S - - 2007
The management of postinfarction ventricular septal defects represents a challenge to both cardiologists and surgeons due to the high morbidity and mortality rate. We report the case of a 79-year-old patient who developed an apical rupture of the ventricular septum, nine days after an anterior myocardial infarction. As the patient ...
Cantinotti Massimiliano - - 2007
Criss-cross heart is a rare congenital heart defect. The unusual arrangement of the atrio-ventricular connection, and associated abnormalities make it a challenging condition to image. We describe 3 cases of criss-cross heart who underwent cardiac MRI in order to comprehensively evaluate the anatomy and plan surgical management.
Bose Alok K - - 2007
The mouse has become a powerful genetic tool for studying genes involved in cardiac development and congenital heart disease. Many of the most severe congenital heart defects are ductal-dependent, resulting in neonatal lethality. Recent advances in ultrasound technology provide an opportunity for the use of high-frequency transducers to characterize the ...
Wurst Keele E - - 2007
BACKGROUND: As part of an effort to validate the General Practice Research Database (GPRD) for future studies of medication use in pregnancy, this study examined whether the rates of all, and specific types of, congenital heart defects obtained from the GPRD are similar to those obtained from UK national systems. ...
Meadows Jeffery - - 2007
OBJECTIVE: Creation or enlargement of a ventricular septal defect is indicated in rare clinical situations. In the setting of double-outlet right ventricle requiring single-ventricle palliation, left ventricular outflow tract obstruction caused by progressive restriction at the ventricular septal defect poses an uncommon but recognized dilemma. In this situation surgical ventricular ...
Eng Marvin H - - 2007
A 60-year-old woman with increasing dyspnea was found to have a para-prosthetic aorto-right ventricular fistula during post-operative evaluation. Due to her multiple sternotomies, she was considered to be high risk for open surgical repair and referred for percutaneous intervention. A 6/4 mm Amplatzer occluder device (AGA Medical, Golden Valley, MN) ...
Harris Matthew A - - 2007
OBJECTIVES: To determine whether delayed-enhancement magnetic resonance imaging can identify fibrous tissue associated with patch reconstructions in postoperative patients with congenital heart disease. Additionally, to determine whether fibrous structures not directly related to the surgical reconstruction exhibited delayed enhancement. METHODS: Seventy-three patients underwent magnetic resonance imaging. Studies were retrospectively reviewed ...
Masoumi Homeyra - - 2007
We report a 9-year-old, previously healthy girl who died suddenly and unexpectedly and was found at postmortem examination to have a cardiac rhabdomyoma, megalencephaly, and an involuting adrenal ganglioneuroma. Her death was possibly caused by a fatal cardiac arrhythmia resulting from interference of the ventricular septal rhabdomyoma with the cardiac ...
Hörer J - - 2007
BACKGROUND: Little is known about prognostic markers for late cardiac-related death after surgical atrial septal defect (ASD) closure in adults. METHODS: Long-term follow-up data of 281 patients who underwent surgical secundum ASD closure when they were older than 30 years, were retrospectively examined. RESULTS: Mean age at surgery was 43.8 ...
van den Akker Nynke M S - - 2007
The importance of vascular endothelial growth factor-A (VEGF) and subsequent Notch signaling in cardiac outflow tract development is generally recognized. Although genetic heterogeneity and mutations of these genes in both humans and mouse models relate to a high susceptibility to develop outflow tract malformations such as tetralogy of Fallot and ...
Ozay B - - 2007
We describe a late complication after ventricular septal defect surgical repair. Proximally, the fistula spread into the right atrium, resulting in an aorta-right atrium fistula. This is a previously unreported iatrogenic complication after a cardiac operation. An aorta-to-right atrial fistula developed within 14 years after closure of an atrial and ...
Diab Karim A - - 2007
Ventricular septal defect is the most common congenital heart malformation. Surgical closure, when indicated, has been practiced for over 50 years with good results; however, surgical closure is still associated with significant morbidity and mortality. Over the past decade, several occluding devices have been developed that made catheter device closure ...
Chou An-Kou - - 2007
Unilateral lung agenesis is a rare congenital defect and could be associated with multiple abnormalities. The patients usually have poor long-term outcomes especially in those with right lung agenesis. We reviewed the 10-year experience in our hospital to describe special clinical features and try to delineate the causes of poor ...
He Guo-Wei - - 2007
Reconstruction of the right ventricular outflow tract (RVOT) is a key procedure in repair of Tetralogy of Fallot (TOF). The procedure creates pulmonary insufficiency (PI) that may compromise the right ventricular (RV) function, particularly during late follow-up. A simple way to reduce PI is to create a monocusp patch from ...
Allan Lindsey - - 2007
Prenatal diagnosis of congenital heart defects has been possible now for over 25 years. This ability has extended from a few specialists to being within the scope of any sonographer engaged in routine obstetric evaluation of the low-risk patient. However, the detection rate is widely varied. The recognition of major ...
de Vos Jacques P - - 2007
Most of the relevant and severe congenital cardiac malfunctions can be recognized in the neonatal period of a child's life. Misclassification of a congenital heart defect may have serious consequences on the long-term outcome of the affected child. Experienced cardiologists can usually evaluate heart murmurs with secure confidence, whereas nonspecialists, ...
Fujimoto Kazuro L - - 2007
Several synthetic materials have been used for cardiac reconstruction in patients with complex congenital heart defects. These materials are not viable, do not grow with children, and may necessitate reoperation. We report here on the cardiac implantation of a recently developed, degradable porous material designed to facilitate cellular ingrowth during ...
Castano Roberto - - 2007
BACKGROUND: In clinical practice a perforation of the nasal septum secondary to an occupational exposure to corrosive chemicals is not considered a sequel of rhinitis. METHODS: Relevant articles published in the last 26 years were searched and retrieved from PubMed. RESULTS: Patients with nasal septal perforations of occupational origin show ...
Nam Sung Chang - - 2007
In budding yeast, G2/M transition is tightly correlated with bud morphogenesis regulated by Swe1 and septin that plays as a scaffold to recruits protein components. BNI5 isolated as a suppressor for septin defect is implicated in septin organization and cytokinesis. The mechanism by which Bni5 regulates normal septin function is ...
Momplaisir Thierry - - 2007
We describe a case of successful percutaneous closure of a moderate-sized paravalvular leak using the Amplatzer septal occluder device in a patient with excessive surgical risk. We were able to successfully close the paravalvular leak without interfering with normal prosthetic valve leaflet function. In patients with severe periprosthetic mitral regurgitation ...
Bonvini Robert F - - 2007
We report the case of a 36-year-old woman admitted for cryptogenic stroke, in whom the Patent Foramen Ovale (PFO) diameter measurement, with a purpose built sizing balloon, performed before the closure procedure, was complicated with the rupture of the inter-atrial septum generating an Atrial Septal Defect (ASD) with a significant ...
Takizawa Hiromitsu - - 2007
Congenital defects of the pericardium are rare. This report describes a young woman with a congenital complete pericardial defect who developed a giant pulmonary cyst. After operation the patient experienced chest pain caused by myocardial ischemia due to cardiac displacement. It is important to note that heart lability in patients ...
Siondalski Piotr - - 2007
We present a 77-year-old female with recent myocardial infarction complicated by antero-apical ventricular septal defect (VSD) and quick development of low cardiac output. Using interrupted horizontal mattress sutures VSD closure was successfully performed on the beating heart. Transthoracic echocardiography at the four-month follow-up did not reveal residual VSD.
Charokopos Nicholas - - 2007
Congenital coronary artery fistulas account for only 0.27%-0.4% of all congenital cardiac defects. We report a case of a right coronary artery (RCA) to a right ventricular(RV) fistula found in 14-year-old girl with clinical signs of heart failure. Echocardiography and cardiac catheterization showed the fistula and a dilated RCA with ...
Manning Peter B - - 2007
Partial atrioventricular (AV) canal represents approximately 25% of all AV septal defects. While often grouped with secundum ASD from the perspective of cardiopulmonary physiology, clinical presentation, and timing of surgical correction, their optimal management truly requires an understanding of their anatomic similarities to other forms of common AVC defects. By ...
Corno Antonio F - - 2007
The anatomic and functional observations made by Francisco Torrent-Guasp, in particular his discovery of the helical ventricular myocardial band (HVMB), have challenged what has been taught to cardiologists and cardiac surgeons over centuries. A literature debate is ongoing, with interdependent articles and comments from supporters and critics. Adequate understanding of ...
Nunn Graham R - - 2007
A single surgeon experience using a modified single patch technique for the repair of 128 patients with complete atrioventricular canal is presented. Thirty-day mortality was 1.6%. Follow-up of these patients has shown no incidence of significant residual ventricular septal defect, a 2.3% incidence of reoperation on the mitral valve, and ...
Koffas H - - 2007
BACKGROUND: Double-chambered right ventricle (DCRV) is a frequently recognized cardiac congenital abnormality in humans. It has been described in dogs and in 1 cat. However systemic description of clinical and echocardiographic features of the disease in cats is currently lacking from the veterinary literature. ANIMALS: Nine cats with DCRV are ...
Butera Gianfranco - - 2007
Ventricular septal defect (VSD) is the most common congenital heart disease. Surgery has been performed for many years and is considered to be the gold standard for the treatment of VSD. However, it is associated with morbidity and mortality. Percutaneous closure of VSDs is performed under general anesthesia and with ...
Pruitt Christopher M - - 2007
We report the case of an adolescent boy who had progressive respiratory distress and cardiovascular compromise after striking his chest against his bicycle handlebars. An echocardiogram in the emergency department revealed a large ventricular septal defect. The boy did well after emergent operative repair and subsequent replacement of a torn ...
WaciƄski Piotr - - 2007
Acute ventricular septal rupture - ventricular septal defect (VSD) following acute myocardial infarction remains a critical condition. We present an 80 year-old patient with an acute VSD following an acute inferior myocardial infarction. Percutaneous VSD closure with an Amplatzer ventricular septal occluder (AVSO) was performed successfully, two days after initial ...
Zannini Lucio - - 2007
During the last 20 years, pediatric cardiac surgery has been characterized by important changes, with reductions in surgical mortality and the achievement of complete repair at an earlier age, thus avoiding multiple procedures and strongly ameliorating the global outcome of these patients. In this review, we describe the actual trends ...
Nikkilä Annamari - - 2007
AIM: The aim of this study was to describe the efficiency of routine prenatal ultrasound screening for the detection of cardiac defects in a Swedish region and to study the effect of prenatal diagnosis on the survival and outcome of the child. METHODS: We identified all fetuses and infants with ...
Crawford Fred A - - 2007
Complete atrioventricular septal defects have been repaired at the Medical University of South Carolina for the past 25 years using the "single-patch technique" as first described by the Mayo Clinic group in 1968. In this technique, the single atrioventricular valve is separated into left (mitral) and right (tricuspid) components by ...
Alonso Alvaro - - 2007
This report describes the presentation and evaluation of an elderly man with uncorrected tetralogy of Fallot. The patient had remained fairly asymptomatic for much of his life. He presented to the hospital at age 86 with new-onset atrial fibrillation with rapid ventricular response and a non-ST-segment elevation myocardial infarction. Transthoracic ...
Kovacikova L - - 2007
BACKGROUND: In neonates, left-sided obstructive heart defects are critical diseases requiring early recognition, initial stabilization, and transfer to Cardiac Center. OBJECTIVES: To assess management of these neonates in primary care hospitals. METHODS: Retrospective analysis of medical records of neonates admitted to Cardiac Intensive Care Unit in whom diagnosis of left-sided ...
Kaldararova M - - 2007
AIM OF THE STUDY: Evaluation of the incidence and severity of late arrhythmias in patients with predisposing congenital heart defects--either due to the anatomy of the defect itself or as a result of a particular type of surgical intervention. PATIENTS AND METHODS: In a retrospective long-term study authors analyzed 158 ...
MacKenzie Ross - - 2007
The presence of widened QRS complexes in a life insurance applicant's electrocardiogram may be due to such things as an intraventricular conduction defect, preexcitation syndrome, left ventricular hypertrophy, ventricular pacing, hyperkalemia and a ventricular rhythm. Clinical information and basic electrocardiogram interpretation techniques can usually narrow the differential diagnosis. Risk assessment ...
Park In-Chul - - 2007
A 5-month-old female Korean Sapsaree dog was presented with severe ascites, cyanosis, respiratory difficulty and exercise intolerance. Diagnostic imaging studies revealed a dextropositioned and over-riding aorta, pulmonary valvular stenosis, ventricular and atrial septal defects, and right ventricular hypertrophy. Based on these findings, the dog was diagnosed as a case of ...
Yalonetsky Sergey - - 2007
We evaluate the yield and safety of coronary angiography (CA) in adult patients who underwent cardiac catheterization for percutaneous transcatheter closure of secundum atrial septal defect (ASD) or patent foramen ovale (PFO). Out of 268 patients, 180 were adults; 82 were adults with ASD and 98 were adults with PFO. ...
Chen Huai-Min - - 2007
To clarify the variant complex congenital cardiac defects, Van Praagh introduced a system of segmental sets to classify the majority of congenital heart diseases, but the code system entails some confusion for complete understanding. We attempted to recategorize the variant sets into four subgroups according to the connection of the ...
Jacquet Luc - - 2007
OBJECTIVE: To describe the ICU outcome and the most frequent complications observed in adult patients operated on for a congenital heart disease. DESIGN AND SETTING: Retrospective analysis of prospectively collected data and chart review in an adult cardiovascular ICU of a university hospital. PATIENTS: 156 patients older than 15 years ...
Aboulhosn Jamil - - 2006
The four characteristic findings in tetralogy of Fallot (TOF) include the following: 1) a malaligned ventricular septal defect; 2) right ventricular outflow and/or pulmonary valve/artery stenosis or atresia; 3) a dextraposed overriding aorta; and 4) right ventricular hypertrophy. This article focuses solely on the outcomes and treatment of surgically corrected ...
Dakak M - - 2006
INTRODUCTION: Isolated congenital sternal cleft in an adult is a very rare anomaly and few cases have been reported so far. Here we report on a successful repair of a sternal cleft associated with an anterior pericardial defect in an adult. MATERIAL AND METHOD: A 20-year-old man presented with a ...
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