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Kara Hasan - - 2014
Chest pain after thoracic trauma may be a symptom of cardiac injury or myocardial infarction. A 63-year-old healthy man had chest pain after blunt chest trauma in a motor vehicle accident. Chest computed tomography scan showed a displaced sternal fracture, lung contusion in the left upper lobe, atelectasis and consolidation ...
Coupez Elisabeth E Department of Cardiology, Clermont-Ferrand University Hospital, Clermont-Ferrand, France; UMR 6284 CNRS-ISIT, Auvergne University, Clermont-Ferrand, - - 2014
Takotsubo cardiomyopathy (TTC) continues to be under-diagnosed, due to its varying presentation, with potentially serious consequences if treatment is delayed. To demonstrate the consistent involvement of catecholaminergic stress in TTC, regardless of the trigger. Between 01 July 2009 and 31 August 2013, patients managed in our centre for thoracic pain ...
Colombo Federico F Division of Cardiology, S. Biagio Hospital, Domodossola, - - 2014
Coronary artery injury after blunt chest trauma is rare, but can be life-threatening, resulting in severe myocardial ischaemia and acute myocardial infarction. We report a case of a 56-year-old male who presented a few days after a blunt chest trauma with crescendo unstable angina. Coronary angiography demonstrated left main coronary ...
Maehara Akiko A Columbia University Medical Center, New York, NY, USA, - - 2014
We assessed whether intravascular ultrasound (IVUS) can detect evidence of coronary perforation that is not visible by coronary angiography. Approximately 15,000 consecutive percutaneous coronary interventions (PCI) performed with IVUS guidance were reviewed retrospectively, pre- and post-PCI IVUS images were compared, and IVUS findings were compared with coronary angiography and in-hospital ...
Hugar Basappa S BS Department of Forensic Medicine, MS Ramaiah Medical College, MSRIT Post, MSR Nagar, Bangalore, 560054, - - 2014
There have been numerous reports of sudden cardiac death following blunt trauma to the chest, but there is lack of such references in forensic literature. It is the court of law which makes decision about trauma precipitating natural events. The forensic pathologist is scientifically trained in the medical field and ...
Audette Jean-Sébastien JS Laval University, Department of Emergency Medicine, 750 Calixa-Lavallée Ave, Unit 7, Quebec, QC G1S 3G6. - - 2014
To describe the use of initial electrocardiogram (ECG), follow-up ECG or equivalent monitoring, and troponin I in patients presenting with sternal fracture who are assessed in emergency departments or by front-line physicians. Multicentre descriptive retrospective study. Two traumatology teaching centres in Quebec city, Que. Fifty-four trauma patients presenting with sternal ...
Radojevic Nemanja N Department of Forensic Medicine, Clinical Centre of Montenegro, Faculty of Medicine, University of Montenegro, Ljubljanska 1, 20000 Podgorica, Montenegro. Electronic address: - - 2014
Myocardial infarctions caused by coronary artery injury after blunt chest trauma is a fatal, but rare occurrence. In the case reported on here, a fatally injured 69-year-old male driver sustained such trauma in a frontal car collision. The autopsy found a laceration of the left anterior descending artery as well ...
Treuth Gregory M GM Delmarva Heart Association, Salisbury, Maryland, - - 2014
A 65-year-old man presented to the emergency department following an anterior chest trauma. He had significant chest pain and chest X-ray was significant for revealed multiple rib fractures and negative. CT scan of the chest ruled out pulmonary embolism or aortic dissection. However, few hours later he developed hypotension requiring ...
Solhpour Amirreza A Division of Cardiology, The University of Texas-Health Science Center, Houston, TX, - - 2014
In the victims of motor vehicle accidents, unrecognized myocardial injuries may pose diagnostic and therapeutic challenges. Herein, we present a case of a 17-year-old man who developed multiple ventricular premature complexes and nonsustained ventricular tachycardia in the setting of blunt chest trauma from a motor vehicle accident. We discuss significance of ...
Bao Weiguo - - 2013
Minimally invasive perventricular closure is emerging as an alternative to conventional open surgery in treating traumatic ventricular septal defects (VSDs). We report a case of successful perventricular closure of a post-traumatic muscular VSD in a patient who sustained blunt chest trauma in a motor vehicle accident. A larger Amplatzer muscular ...
Masuoka Ayumu A Department of Pediatric Cardiac Surgery, Saitama Medical University International Medical Center, Saitama, Japan - - 2013
Few reports have described traumatic heart injury in children. We describe a case of acute mitral regurgitation associated with papillary muscle rupture, traumatic ventricular septal defect, and impending left ventricular free wall rupture due to blunt trauma in a 2-year-old girl. The papillary muscle was sutured to the left ventricular ...
Ryu Dae Woong DW Department of Thoracic and Cardiovascular Surgery, College of Medicine, Wonkwang University, Iksan, Jeonbuk, Republic of - - 2013
Cardiac rupture after blunt trauma is rare and associated with high mortality. The anatomic pattern of blunt cardiac rupture has been demonstrated with the right cardiac chambers more frequently affected than the left. Furthermore, left atrial injury is usually restricted to the atrial appendage and the pulmonary vein-atrial junction. Herein, ...
Pillai Rajesh Sadanandan - - 2013
Ventricular septal rupture occurring as a result of blunt trauma is a very rare clinical condition. Compression of the heart between the sternum and the vertebral column during late diastole or isovolumetric contraction resulting in sudden increase in the intracardiac pressure is a prerequisite for its occurrence. Sudden relief of ...
Theodoropoulos Ioannis - - 2013
BACKGROUND: Cardiac valve injury after blunt chest trauma is extremely rare, and the tricuspid valve is most commonly affected because of the anterior location of the right ventricle. Tricuspid valve insufficiency can range from a subclinical presentation to acute cardiac failure. OBJECTIVE: Diagnosis is difficult in trauma patients because hypotension ...
Patil Rahul R - - 2013
A young male following road traffic accident (RTA) with head injury and parietal bleed was diagnosed with STEMI based on ECG findings which is rare occurrence. Coronary angiography showed thrombotic ostial occlusion of LAD. Successful primary angioplasty using thrombo-aspiration was done, in difficult clinical scenario. The case was challenging in ...
Krpata David M - - 2013
We present a case of a 15 year old girl who developed transient left ventricular apical ballooning syndrome, Tako-tsubo cardiomyopathy, after a significant motor vehicle accident. On post-trauma day three she developed heart failure with mid-to-apical left ventricular wall dysfunction with an EF of 10%-15%. The patient eventually regained full ...
Alhaji Mohammad - - 2013
Intermittent left bundle branch block (LBBB) has been reported in the literature following certain conditions such as cardiac blunt trauma, myocardial infarction (MI) or exercise induced LBBB. In the majority of cases, the patients usually have underlying coronary arteries disease. LBBB often prevents the electrocardiographic diagnosis of acute MI; therefore, ...
Molardi Alberto - - 2013
Cardiac injuries from blunt chest trauma are usually the result of motor vehicle accidents; cardiac injuries result in 20% of such accidents, but they are also associate to mild-to-moderate sports injuries.The severity of external injuries does not necessary reflect the severity of cardiac trauma. Blunt chest trauma can cause a ...
Ozdoğan Oner - - 2013
Coronary artery dissection is a rare complication after blunt chest trauma. Patients usually present with sudden death and the diagnosis is frequently missed. In this report, we present a case of a 46-year-old with a hyperacute anterior wall myocardial infarction after blunt chest trauma. Diagnostic coronary angiography showed total occlusion ...
Arora Sonali S Department of Internal Medicine, Baystate Medical Center/Tufts University School of Medicine, Springfield, MA, - - 2013
A cardio-embolic stroke as a sequela of remote blunt chest trauma is a rare clinical presentation. Blunt chest trauma can cause various acute cardiac complications like arrhythmias, cardiac contusion etc. However, delayed consequences such as left ventricular thrombus resulting in thromboembolic phenomena are reported infrequently. A 30-year-old healthy man presented ...
Felten Marie-Louise ML Department of Anesthesiology, Foch Hospital, Suresnes, - - 2013
Pneumopericardium is rare and has been reported secondary to chest trauma. We report a case of tension pneumopericardium occurring during double-lung transplantation, where intraoperative transoesophageal echocardiography first showed a hypokinetic left ventricle and a few minutes later a compression of its anterolateral portion due to pneumopericardium. Although the pericardium was ...
Vishwas Mellekate Shadaksharappa - - 2013
Typical causes of internuclear ophthalmoplegia (INO) include arterial infarcts, demyelinating conditions, inflammation and trauma. We here report the unique case of a 33-year-old man with INO of the right eye caused by infarction of the right midbrain, confirmed by diffusion-weighted MRI. At presentation he displayed impaired adduction of the right ...
Yoann Launey L Anesthesiology, Critical Care and Emergencies, Rennes University Hospital, 35000 Rennes, France ; Anesthesiology, Critical Care, Emergencies, and SAMU (Service d'Aide Médicale Urgente), Rennes 1 University, Inserm U991, Centre Hospitalier Universitaire (CHU) Pontchaillou, 35000 Rennes, - - 2013
This report presents a case of severe blunt chest trauma secondary to a horse riding accident with resultant free-wall rupture of the left ventricle in association with severe lung contusion. We describe the initial surgical and medical management of the cardiac rupture which was associated with a massive haemoptysis due ...
Salooja Manpreet S - - 2013
Blunt traumatic cardiac rupture is associated with a high mortality rate. Motor vehicle accidents account for most cardiac ruptures, but crush injury is relatively rare. We describe a case of a 72-year-old man who had the left atrial appendage ruptured through blunt trauma due to a fall from scooter. Simple ...
Steed Maura - - 2012
Traumatic ventricular septal defect is an uncommon complication of blunt chest trauma. We report a case of ventricular septal avulsion, associated with traumatic ventricular septal defect and the associated management concerns.
De'Ath Henry D I - - 2012
A young adult pedestrian was admitted to hospital after being hit by a car. On arrival to the Accident and Emergency Department, the patient was tachycardic, hypotensive, hypoxic, and acidotic with a Glasgow Coma Scale of 3. Despite initial interventions, the patient remained persistently hypotensive. An echocardiogram demonstrated a traumatic ...
Bourantas Christos V - - 2012
Bioresorbable scaffolds (BRS) represent a novel approach in coronary stent technology. In contrast to the metallic stents, they provide transient scaffolding, thereby safeguarding early vessel patency and acute gain. Subsequently a process of "decomposition" occurs, that results in the complete absorption of the scaffold. This reduces the risk of late ...
Bock Jeremy S - - 2012
Blunt chest trauma represents a spectrum of injuries to the heart and aorta that vary markedly in character and severity. The setting, signs, and symptoms of chest trauma are often nonspecific, which represents a challenge to emergency providers. Individuals with suspected blunt chest trauma who have only mild or no ...
Karimi-Ashtiani Shahryar - - 2012
Changes in myocardial wall motion and thickening during myocardial perfusion SPECT are typically assessed separately from gated studies for the presence of stress-induced functional abnormalities. We sought to develop and validate a novel approach for automatic quantification of rest-stress myocardial motion and thickening changes (MTCs). Endocardial surfaces at the end-diastolic ...
Ciaccio Edward J - - 2012
Spectral Profiles of CFAE. Background: Spectral analysis of complex fractionated atrial electrograms (CFAE) may be useful for gaining insight into mechanisms underlying paroxysmal and longstanding atrial fibrillation (AF). The commonly used dominant frequency (DF) measurement has limitations. Method: CFAE recordings were acquired from outside the 4 pulmonary vein ostia and ...
Motwani Manish - - 2012
BACKGROUND: -Although accelerated high-spatial-resolution perfusion-CMR has been shown to be clinically feasible, there has not yet been a direct comparison with standard-resolution methods. We hypothesised that higher spatial resolution detects more subendocardial ischemia and leads to greater diagnostic accuracy for the detection CAD. This study compared the diagnostic accuracy of ...
Regueiro Ander - - 2012
Chest trauma is a major health problem with a high mortality. Myocardial infarction secondary to coronary dissection following blunt chest trauma is a rare entity. We describe the case of an inferior MI following blunt chest trauma. A 61-year-old male without any relevant medical history was transported to a hospital ...
Yu Fei F Biomedical Engineering and Cardiovascular Medicine, University of Southern California, Los Angeles, CA, - - 2012
The zebrafish (Danio rerio) is an emerging genetic model for regenerative medicine. In humans, myocardial infarction results in the irreversible loss of cardiomyocytes. However, zebrafish hearts fully regenerate after a 20% ventricular resection, without either scarring or arrhythmias. To study this cardiac regeneration, we developed implantable flexible multi-microelectrode membrane arrays ...
Ptaszek Leon M - - 2012
Development of regenerative therapeutic strategies to reverse the progression of advanced heart failure is one of the most urgent clinical needs of this century. Insights gained from clinical trials of adult stem cells, together with fundamental scientific advances in cardiac stem cell and regenerative biology, are beginning to yield potential ...
Srinivas Sunil Kumar - - 2012
A 78-year-old man admitted with complaints of breathlessness of 1 year and typical chest pain of 2 months duration. He had a blunt chest trauma 7 years back. Transthoracic echocardiography revealed severe tricuspid regurgitation due to a flail anterior leaflet of the tricuspid valve. It also revealed global left ventricular dysfunction. Flail tricuspid ...
Gottam Nithin - - 2012
Blunt chest trauma can lead to a variety of cardiac injuries, one of which is nonatherosclerotic myocardial infarction caused by intimal laceration and thrombotic process activation. Here we present a case of anterior myocardial infarction secondary to blunt trauma involving a kick to the chest.
Nagel Bert - - 2012
Left ventricular hypertrabeculation/noncompaction (LVHT) is a cardiac abnormality of unknown etiology which has been described in children as well as in adults with and without chromosomal aberrations. LVHT has been reported in association with various cardiac and extracardiac abnormalities like epilepsy and facial dysmorphism. A unique combination of LVHT, atrial ...
Krejčí E E Institute of Anatomy, First Faculty of Medicine, Charles University, Prague, Czech - - 2012
The left and right ventricle originate from distinct parts of the cardiac tube, and several genes are known to be differentially expressed in these compartments. The aims of this study were to determine developmental differences in gene expression between the left and right ventricle, and to assess the effect of ...
Mohammed Ilyas - - 2011
Atrial Fibrillation (AF) is a common arrhythmia associated with substantial morbidity and mortality, particularly due to thromboembolic strokes, the prevalence of which is expected to rise over the next few decades. This article reviews the complex mechanisms behind thromboembolism, compares the newer risk stratification models for identifying those at risk ...
Feng Yuliang - - 2011
MicroRNAs (miRNAs) are small noncoding RNAs that are emerging as pivotal modulators in virtually all aspects of cardiac biology, from cardiac development to cardiomyocyte survival and hypertrophy. The miRNA profiling, following gain- and loss-of-function studies using in vitro and in vivo models, has identified wide-ranging functions for miRNAs in the ...
Didon Jean-Philippe - - 2011
AIMS: Shortening hands-off intervals can improve benefits from defibrillation. This study presents the performance of a shock advisory system (SAS), which aims to decrease the pre-shock pauses by triggering fast rhythm analysis at minimal delay after end of chest compressions (CC). METHODS: The SAS is evaluated on a database of ...
Gärtner Anna - - 2011
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited cardiomyopathy primarily of the right ventricle characterized through fibrofatty replacement of cardiomyocytes. The genetic etiology in ARVC patients is most commonly caused by dominant inheritance and high genetic heterogeneity. Though histological examinations of ARVC affected human myocardium reveals fibrolipomatous replacement, the molecular ...
Lang Roberto M - - 2011
Significant advances in 3-dimensional echocardiography (3DE) technology have ushered its use into clinical practice. The recent advent of real-time 3DE using matrix array transthoracic and transesophageal transducers has resulted in improved image spatial resolution, and therefore, enhanced visualization of the pathomorphological features of the cardiac valves compared with previously used ...
Lim Shiang Y SY The Hatter Cardiovascular Institute, University College London Hospital and Medical School, London, - - 2011
The pharmacological inhibition or genetic ablation of cyclophilin-D (CypD), a critical regulator of the mitochondrial permeability transition pore (mPTP), confers myocardial resistance to acute ischemia-reperfusion injury, but its role in post-myocardial infarction (MI) heart failure is unknown. The aim of this study was to determine whether mitochondrial CypD is also ...
Li Jing-Sha - - 2011
AIMS: This study aimed to determine whether (a) there was an imbalance between matrix metalloproteinase 9 (MMP-9) and tissue inhibitor of metalloproteinase 1 (TIMP-1) after cardiopulmonary resuscitation (CPR) in a canine model of prolonged ventricular fibrillation (VF); (b) with the duration of VF, the degree of the imbalance would be ...
Lindsey Jason B - - 2011
BACKGROUND: <0.001). Spline analysis using peak CK-MB as a continuous variable suggested a graded, nonlinear relationship with 1-year mortality, with an inflection point at ≈30 ng/mL.Conclusions-Among unselected patients undergoing PCI, there is a graded relationship between CK-MB elevation after PCI and 1-year mortality that is particularly strong for large CK-MB ...
Bodson Laurent - - 2011
Cardiac alterations may be defined as changes that lead to abnormal cardiac function. They include decrease in preload, increase in afterload, and depressed cardiac contractility. Cardiac dysfunction differs from cardiac failure: cardiac performance is altered, but this does not necessarily mean that the cardiovascular system is failing. Several tools are ...
Griffin Julian L JL MRC Human Nutrition Research, Elsie Widdowson Laboratory, Fulbourn Road, Cambridge CB1 9NL, UK. jules.griffin@ - - 2011
Metabolomics represents a paradigm shift in metabolic research, away from approaches that focus on a limited number of enzymatic reactions or single pathways, to approaches that attempt to capture the complexity of metabolic networks. Additionally, the high-throughput nature of metabolomics makes it ideal to perform biomarker screens for diseases or ...
Lin David - - 2011
To date, gene expression studies related to chronic heart failure (CHF) have mainly involved microarray analysis of myocardial tissues. The potential utility of blood to infer the etiology, pathogenesis, and course of CHF remains unclear. Further, the use of proteomic and metabolomic platforms for molecular profiling of CHF is relatively ...
Welinder Annika - - 2011
Cardiac magnetic resonance (CMR) is currently considered the reference standard for in vivo assessment of myocardial infarction (MI). There is, however, no international consensus on how MI quantification from CMR should be performed. The aim of this study was to test how previously published manual quantification of MI using CMR ...
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