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Kalra Ankur A Minneapolis Heart Institute at Abbott Northwestern Hospital, Minneapolis, MN, USA, - - 2014
Spontaneous coronary artery dissection (SCAD) is a rare, life-threatening condition that usually manifests as an acute myocardial infarction. Diagnosing SCAD with conventional coronary angiogram can be challenging, particularly if the true lumen is severely narrowed. Our case highlights the challenges in performing successful percutaneous coronary intervention (PCI) in patients with ...
Avegliano Gustavo G Cardiovascular Institute of Buenos Aires, Buenos Aires, - - 2014
Lateral left ventricular wall rupture (LVWR) is a rare complication following acute myocardial infarction (AMI) less than 1%. After cardiogenic shock, LVWR constitutes the most common cause of in-hospital death in AMI patients. Around 40% of all LVWR occurred during the first 24 hours and 85% within the first week. In ...
Newby Andrew C AC University of Bristol and Bristol Heart Institute, Bristol, - - 2014
To review progress over the past 5 years in relating extracellular proteinases to plaque rupture, the cause of most myocardial infarctions, and consider the most promising prospects for developing related treatments. Cysteinyl cathepsins have been implicated in multiple macrophage functions that could promote plaque rupture. Cathepsin K is an attractive ...
Lundblad Runar R Department of Thoracic and Cardiovascular Surgery, Oslo University Hospital, Rikshospitalet, Oslo, Norway. Electronic address: - - 2014
David infarct exclusion and Daggett direct septal closure are alternative techniques to repair postinfarction ventricular septal rupture. The aim of the present study was to compare the 2 methods with regard to postoperative morbidity, 30-day mortality, and long-term survival. From May 1981 to December 2010, 110 patients underwent surgery for ...
Nunes Rafael A B RA Department of Cardiology, Hospital São Camilo Santana, São Paulo, Brazil; Heart Institute (InCor), University of São Paulo Medical School, Brazil. Electronic address: - - 2014
Coronary pseudoaneurysms are an unusual finding during coronary angiography and there are very little data on their prognosis in the literature. We report the case of a 62-year-old man admitted with an anterior myocardial infarction who developed a pseudoaneurysm in the mid left anterior descending artery some days after a ...
Takahashi Hiroaki H Department of Cardiac Surgery, University Hospital Heidelberg, Heidelberg, - - 2014
Postinfarction ventricular septal rupture is a serious complication associated with high hospital mortality rates. The present study aimed to identify predictors of early and late outcome in patients with postinfarction ventricular septal defect over a period of 30 years. We retrospectively analysed clinical and operative data, predictors of early mortality ...
Jones Brandon M BM Department of Cardiovascular Medicine, Cleveland Clinic Foundation, 9500 Euclid Ave, Desk J2-3, Cleveland, OH 44195, - - 2014
Ventricular septal rupture (VSR) after acute myocardial infarction is increasingly rare in the percutaneous coronary intervention era but mortality remains high. Prompt diagnosis is key and definitive surgery, though challenging and associated with high mortality, remains the treatment of choice. Alternatively, delaying surgery in stable patients may provide better results. ...
Nasir Abdul A Lancashire Cardiac Centre, Blackpool Victoria Hospital, Blackpool, UK - - 2014
A best evidence topic was written according to a structured protocol. The question addressed was whether conservative or surgical management would result in better outcomes in patients presenting with left ventricular free wall rupture (LVFWR) following acute myocardial infarction. Surgical techniques involved were infarctectomy + patch repair, suturing of an ...
Ahmed Mustafa I MI Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, Birmingham, - - 2014
We describe the incremental value of live/real time three-dimensional (3D) echocardiography over the 2D technique in the assessment of ruptured right sinus of Valsalva into the right ventricle associated with an adjacent perimembranous ventricular septal defect in an elderly patient.
Vazquez Alejandro A Department of Cardiac Surgery, Hospital Universitari i Politècnic La Fe, Valencia, Spain - - 2014
Left ventricular free wall rupture and acute ischaemic mitral regurgitation are nowadays rare, but still potentially lethal mechanical complications after acute myocardial infarction. We report a case of a sequential left ventricular free wall rupture, anterolateral papillary muscle disruption, secondary severe mitral regurgitation and subsequent posteromedial papillary muscle head rupture ...
Kuijpers Marijke J E MJ From the Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands (M.J.E.K., P.E.J.v.d.M., M.A.H.F., N.J.A.M., J.G.-R., J.W.M.H., J.M.E.M.C.); CSL Behring GmbH, Marburg, Germany (F.M.); Department of Experimental Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (J.C.M.M.); Department of Plasma Proteins, Sanquin, Amsterdam, The Netherlands (J.C.M.M.); Clinical Chemistry, Department of Molecular Medicine and Surgery, Karolinska Institutet and University Hospital, Stockholm, Sweden (T.R.); and Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Hamburg-Eppendorf, Hamburg, Germany - - 2014
Atherothrombosis is the main cause of myocardial infarction and ischemic stroke. Although the extrinsic (tissue factor-factor VIIa [FVIIa]) pathway is considered as a major trigger of coagulation in atherothrombosis, the role of the intrinsic coagulation pathway via coagulation FXII herein is unknown. Here, we studied the roles of the extrinsic ...
di Summa Michele M Department of Cardiothoracic and Vascular Surgery, Kenyatta National Hospital and University of Nairobi, Nairobi, - - 2014
A pseudoaneurysm of the ventricle is formed when there is rupture of the myocardial wall with the discontinuity being roofed over by the pericardium and mural thrombus or fibrous tissue without myocardial elements. Cardiac pseudoaneurysm is a rare and a potentially life-threatening event. Early prophylactic surgical aneurysmectomy has been the ...
Shah Nadim N Department of Cardiology, Wellington Hospital, Wellington, New Zealand. Electronic address: - - 2014
Spontaneous coronary artery dissection (SCAD) is a rare but a serious cause of myocardial ischaemia and infarction that occurs most frequently in younger female patients. The management of this rare condition remains controversial. In this case series we describe the spectrum of outcomes observed following conservative management.
Mahesh Balakrishnan B Department of Cardiothoracic Surgery, Papworth Hospital, Cambridge, - - 2014
Left ventricular free wall rupture secondary to myocardial infarction is an uncommon but catastrophic event requiring emergency surgery. We describe a unique presentation of left ventricular free wall rupture as delayed tamponade caused by a gradually expanding pseudoaneurysm compressing the left atrium, leading to pulmonary congestion that required increasing respiratory ...
Vervaeke Hannes - - 2014
We report the case of a 62-year-old woman presenting with symptoms and findings of myocardial infarction and a left ventricular free wall rupture. Coronary angiography revealed a critical stenosis in the middle right coronary artery. A contrast left ventriculogram revealed extravasation of contrast through the inferolateral wall of the left ...
Lee Myles E ME Department of Cardiothoracic Surgery (Drs. A. Lee and M. Lee), St. Francis Medical Center, Lynwood, California 90262; and pre-medical student (Ms Tamboli), Washington University, St. Louis, Missouri - - 2014
One difficulty with external repair of left ventricular rupture after mitral valve replacement is collateral bleeding in friable myocardium adjacent to the rupture. The bleeding is caused by tension on the closing sutures, whether or not pledgets have been used. We report the case of a 69-year-old woman who underwent ...
Vaishnava Prashant P From the Department of Medicine, Samuel and Jean A. Frankel Cardiovascular Center, University of Michigan Health System and Medical School, Ann - - 2014
The past four decades have seen remarkable progress in establishing best perioperative practices.(1) One of the challenges in improving perioperative care, however, is rooted in the interplay of the myriad interdependent, often opposing, mechanisms that contribute to perioperative myocardial infarction - excess bleeding, dramatic fluid shifts, unrelenting tachycardia, myocardial stress ...
Ozaki Yuichi Y Department of Cardiovascular Medicine, Wakayama Medical University, 811-1, Kimiidera, Wakayama 641-8510, - - 2014
Although monocytes appear to be actively involved in the onset of acute coronary syndrome (ACS), they are heterogenous in human peripheral blood. How up-regulation of monocyte subsets leads to coronary plaque rupture followed by thrombus formation remains unclear. Recent studies have shown that P-selectin glycoprotein ligand-1 (PSGL-1) is involved in ...
Aoyagi Shigeaki S Department of Cardiovascular Surgery, Cardiovascular Center, Munakata Suikokai General Hospital, Fukuoka, - - 2014
We report three cases of left ventricular free wall rupture (LVFWR) after acute myocardial infarction, which were repaired using a sutureless technique without cardiopulmonary bypass. At operation, a sheet of fibrin tissue-adhesive collagen fleece (TachoComb) was secured to the hematoma surrounding the tear and the infarcted area under compression by ...
Doi Toshio T First Department of Surgery, University of Toyama, Toyama, Toyama, - - 2014
Papillary muscle rupture is a lethal complication of after acute myocardial infarction. We report the successful surgical management of complete anterolateral papillary muscle rupture associated with cardiogenic shock in an 80-year-old woman. The patient was admitted with the sudden onset of chest pain and dyspnea. After hemodynamics deteriorated rapidly, she ...
Nagai Toshiyuki T Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan (T.N., S.H., Y.S., Y.A., K.K., M.I., S.Y., H.O., - - 2014
Dendritic cells (DC) play pivotal roles in regulating the immune system and inflammatory response. We previously reported DC infiltration in the infarcted heart and its immunoprotective roles in the post-infarction healing process after experimental myocardial infarction (MI). However, its clinical significance has not been determined. The degree of DC infiltration ...
Joshi Nikhil V NV Centre for Cardiovascular Science, Clinical Research Imaging Centre, and Division of Pathology, University of Edinburgh, Edinburgh, UK. Electronic address: - - 2014
The use of non-invasive imaging to identify ruptured or high-risk coronary atherosclerotic plaques would represent a major clinical advance for prevention and treatment of coronary artery disease. We used combined PET and CT to identify ruptured and high-risk atherosclerotic plaques using the radioactive tracers (18)F-sodium fluoride ((18)F-NaF) and (18)F-fluorodeoxyglucose ((18)F-FDG). ...
Nalliah Chrishan J - - 2013
Ventricular tachycardia (VT) induction at electrophysiological (EP) study early after ST elevation myocardial infarction (STEMI) has been a predictor of spontaneous ventricular arrhythmia. Reperfusion therapy for STEMI may have resulted in altered VT character. We attempted to determine differences in VT cycle length (CL) and VT recurrence rates, in patients ...
Alpert Joseph S JS Sarver Heart Center, University of Arizona College of Medicine, Tucson. Electronic address: - - 2014
The Task Force for the Universal Definition of Myocardial Infarction recently published updated guidelines for the clinical and research diagnosis of myocardial infarction under a variety of circumstances and in a variety of categories. A type 1 myocardial infarction (MI) is usually the result of atherosclerotic coronary artery disease with ...
Marella Punnaiah P Department of Internal Medicine, Banner Estrella Medical Center, Phoenix, AZ, - - 2013
Cardiac rupture is a very important but under-recognized complication of acute myocardial infarction and usually happens within a week of the event. Sometimes it can be subacute and may not be typical of an acute blow out rupture. Hence careful evaluation is needed as a missed or delayed diagnosis can ...
Legutko Jacek - - 2013
Using radiofrequency-intravascular ultrasound (VH-IVUS), we have previously demonstrated that in 50% of patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention with optimal angiographic result, the stent does not fully cover the whole VH-IVUS-derived thin-cap fibroatheroma (VH-TCFA) related to the culprit lesion. Presently, we set out to ...
Morokuma Hiroyuki H Department of Thoracic and Cardiovascular Surgery, Fukuoka Tokushukai Hospital, Kasuga, Fukuoka, Japan - - 2013
A 66-year-old man was referred in cardiogenic shock due to acute myocardial infarction. Echocardiography revealed severe mitral regurgitation with prolapse of the posterior mitral leaflet due to papillary muscle rupture. Emergency coronary angiography showed subtotal occlusion of the left circumflex coronary artery. A percutaneous coronary intervention was performed immediately. After ...
Okonogi Taichi - - 2013
Left ventricular free wall rupture is a rare, but occasionally lethal, complication after acute myocardial infarction (AMI). This case report describes a patient who presented with cardiogenic shock due to oozing-type rupture secondary to AMI and successfully underwent percutaneous intrapericardial fibrin-glue injection therapy. Cardiac magnetic resonance imaging demonstrated the thin ...
Byrne Robert A - - 2013
The dominant cause of ST-segment elevation myocardial infarction (STEMI) is abrupt plaque rupture, erosion, or hemorrhage with secondary intravascular thrombosis, typically leading to coronary arterial occlusion and infarction of the downstream myocardium.(1) Contemporary evidence-based intervention strategies incorporating rapid administration of antiplatelet and antithrombotic medications and prompt revascularization with primary percutaneous ...
Hsieh Yung-Kun - - 2013
Sutureless repair is an effective procedure for acute left ventricular free wall rupture; however, it may be complicated with a left ventricular pseudoaneurysm during the late postoperative period. We present a case of a large ventricular pseudoaneurysm that occurred after the sutureless repair of an inferior myocardial infarction with oozing ...
Juvet Tristan - - 2013
Patients presenting with traumatic cardiac rupture are unlikely to survive lengthy transfers from the trauma scene to a hospital. However, in patients with a previous sternotomy, adhesions may divert cardiac hemorrhage, allowing hemodynamic management to be successful. We present an 83-year-old male with a history of coronary artery bypass grafting ...
Lindefjeld Dante S - - 2013
Coronary pseudoaneurysms are rare complications of coronary perforation or dissection that can progress to rupture and cardiac tamponade. There is no optimal standard treatment, and their management is often guided by individual criteria including the risk of rupture, location in the coronary tree, size and flow in it. All of ...
Eitan A - - 2013
ìAcute coronary syndrome (ACS), a spectrum of clinical scenarios including ST-segment elevation myocardial infarction, non-ST-segment elevation myocardial infarction and unstable angina, is one of the main reasons of hospital admissions and the leading cause of mortality in the developed nations. The underlying pathological substrate in ACS is a rupture of ...
Deprez Fabrice C - - 2013
We report the case of a 61-year-old male patient who suffered a spontaneous (atraumatic) splenic rupture (SSR) following splenic infarction treated by heparin anticoagulation. Splenic rupture precipitated by thrombolytic or anticoagulant therapy has been reported and putatively attributed to unrecognized micro-traumatisms i.e. after resuscitation manoeuvres, leading to massive bleeding upon ...
Libby Peter P Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. - - 2013
The core of an atheromatous plaque contains lipids, macrophages, and cellular debris, typically covered by a fibrous cap that separates the thrombogenic core from the blood. Rupture of the fibrous cap causes most fatal myocardial infarctions. Interstitial collagen confers tensile strength on the cap, as it does in skin and ...
Hamamoto Masaki M Department of Cardiovascular Surgery, Onomichi General Hospital, Hiroshima, - - 2013
We experienced 2 cases of left ventricular pseudoaneurysm located at the posterolateral wall. Case 1 was an 80-year-old woman who developed a left ventricular pseudoaneurysm 4 months after sutureless repair of left ventricular free wall rupture due to acute myocardial infarction. The pseudoaneurysm was repaired through a left thoracotomy. Case ...
Chung Hyemoon - - 2013
Spontaneous coronary artery dissection (SCAD) is a rare and occasionally life-threatening cause of acute coronary syndrome. Patients may present with clinical scenarios ranging from angina pectoris to cardiogenic shock to sudden cardiac death, and it may be a potentially life-threatening condition if not recognized. However, its etiology, pathophysiology and optimal ...
Desai Heena M HM Department of Pathology, T.N. Medical College and B.Y.L. Nair Charitable Hospital, Mumbai Central, Mumbai, India. - - 2013
Rupture of the myocardium due to myocardial infarction is often fatal but when such patients survive, they present with a pseudoaneurysm where the defect is sealed by the pericardium preventing the complete rupture. This is described as a 'contained myocardial rupture'. We describe here a case of left ventricular contained ...
Chang Wei-Ting - - 2013
The entrapment of a ruptured catheter balloon during percutaneous coronary intervention (PCI) is rare, but it can lead to life-threatening complications, such as myocardial infarction (MI) and lethal arrhythmias. Ruptured balloon entrapment usually occurs in either tortuous, calcified, or angulated coronary lesions without adequate balloon deflation. The avoidance of drastic ...
Isoda Susumu - - 2013
A left ventricular (LV) free wall rupture is a highly lethal condition. A 78-year-old female, who collapsed while riding a bike, was admitted to our emergency service 7 days after experiencing chest pain. During admission, she had cardiopulmonary arrest. Though cardiopulmonary resuscitation was successful, computed tomography (CT) showed cardiac tamponade. ...
Gregoric Igor D - - 2013
We describe the case of a 54-year-old woman with a postinfarction ventricular septal defect (VSD) and ventricular free wall rupture who was stabilized with a percutaneous ventricular assist device (pVAD) to allow for myocardial infarct stabilization. Following the rupture of the right ventricular free wall and cardiopulmonary arrest on hospital ...
Gassenmaier Tobias - - 2013
A 74-year-old man was admitted to the cardiac catheterization laboratory with acute myocardial infarction. After successful angioplasty and stent implantation into the right coronary artery, he developed cardiogenic shock the following day. Echocardiography showed ventricular septal rupture. Cardiac magnet resonance imaging (MRI) was performed on the critically ill patient and ...
Vatan B - - 2013
Left ventricular free wall rupture due to acute myocardial infarction (MI) is an infrequent but fatal complication that occurs especially during the 1st week of MI. Emergency surgical intervention is essential but conveys significant operative mortality. Most of the patients die before they reach the operating room. We present a ...
Noorani Alia A Department of Cardiothoracic Surgery, Papworth Hospital, Cambridge, - - 2013
Ventricular free wall rupture is a rare, usually fatal complication of acute myocardial infarction. Subacute free wall rupture with pseudoaneurysm formation is even rarer, but may be associated with a chance of survival if surgery is performed expeditiously. Although rupture of the left ventricle is more common, right-sided rupture has ...
Kang Soo-Jin - - 2013
OBJECTIVES: We report optical coherence tomography (OCT) findings in 33 patients who presented with very late stent thrombosis (VLST) after either drug-eluting stent (DES) or bare-metal stent (BMS) implantation. BACKGROUND: VLST is a potentially life-threatening complication, but the underlying mechanisms remain unclear. METHODS: In 33 patients (27 DES- and 6 ...
Silbiger Jeffrey J - - 2013
Left ventricular (LV) false tendons are chordlike structures that traverse the LV cavity. They attach to the septum, to the papillary muscles, or to the free wall of the ventricle but not to the mitral valve. They are found in approximately half of human hearts examined at autopsy. Although it ...
Lee Cheol Whan - - 2013
It remains uncertain whether the histology of culprit coronary plaques differs between ST-segment elevation myocardial infarction (STEMI) and non-STEMI (NSTEMI). We compared intravascular ultrasound (IVUS) and histologic findings in coronary culprit plaques among patients presenting with STEMI and NSTEMI. Atherectomy specimens were obtained from 96 patients, 70 with STEMI and ...
Cho Jae Hyung - - 2013
BACKGROUND: Ventricular septal rupture is a potentially fatal complication of acute myocardial infarction. Its incidence has declined with modern reperfusion therapy. In the era of percutaneous coronary interventions, it occurs a median of 18--24 hours after myocardial infarction and is most commonly associated with anterior myocardial infarction. We present a ...
Hiraoka Toshifumi - - 2013
A 57-year-old man had been followed up for severe left ventricular dysfunction after acute myocardial infarction with a left ventricular thrombus. He had been treated with anticoagulant and antiplatelet therapy and was admitted to our hospital because of abdominal pain and shock. He had no prior episode of trauma. The ...
Narula Jagat J Mount Sinai School of Medicine, New York, New York 10029, USA. - - 2013
The goal of this study was to identify histomorphologic characteristics of atherosclerotic plaques and to determine the amenability of some of these components to be used as markers for invasive and noninvasive imaging. Rupture of the atherosclerotic plaques is responsible for the majority of acute coronary events, and the culprit ...
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