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Hayano Shinji - - 2012
It is well known that chronic kidney disease is a risk factor for atherosclerosis. The present study was conducted to identify any relation between the estimated glomerular filtration rate (eGFR) and coronary plaque characteristics using integrated backscatter intravascular ultrasound (IB-IVUS), which can detect coronary plaque composition. We performed IB-IVUS for ...
Luijkx Tim - - 2012
BackgroundPhysiological cardiac adaptation in athletes is influenced by body surface area, gender, age, training intensity and sport type. This study assesses the influence of sport category and provides a physiological reference for sport category and gender.MethodsThree hundred and eighty-one subjects (mean age 25±5 years, range 18 to 39 years; 61% ...
Chiu Cheng-An - - 2012
We demonstrated that visfatin expressed in monocytes and neutrophils and increased their reactivity in male acute ST-segment elevation myocardial infarction patients. Furthermore, visfatin was strongly appeared in lipid rich coronary rupture plaques and macrophages. These results suggest another explanation about leukocytes mediated visfatin that may play a pathogenesis role in ...
Gorman Richard - - 2012
Cardiac tamponade is a life-threatening and time-critical emergency that requires early recognition and prompt management often alongside other resuscitation considerations. The use of ultrasound in the primary survey greatly assists in the early diagnosis allowing preparations for early definitive management to be made. An unusual case of right ventricular rupture ...
Gottam Nithin - - 2012
Left main coronary artery (LMCA) thrombus is a clinically rare event and is thought to be secondary to plaque rupture with subsequent thrombus formation, persistent hypercoagulable state, cocaine use, or vasospasm. (Klein et al., 2008) here we present a case of LMCA thrombus that presented as an ST elevation myocardial ...
Puhlman Mark - - 2012
Left ventricular assist devices (LVADs) have become accepted as treatment for heart failure as a result of improvements in diagnosing and treating left ventricular failure and limited donor availability. In the Pivotal Study of the HeartMate II in the bridge to transplantation population, the incidence of right ventricular failure without ...
Dubey Laxman - - 2012
Left ventricular (LV) pseudoaneurysm is a rare but potentially lethal complication of acute myocardial infarction (MI). We report a very rare case of a 60 year-old woman with a ruptured myocardial wall, and a non-ruptured LV pseudoaneurysm. The patient presented with acutely worsening shortness of breath and exertional dyspnea of ...
Roa-Castro Víctor Hugo - - 2012
Pseudoaneurysm of the left ventricle is rare and may occur as a result of transmural myocardial infarction. The course of rupture after acute myocardial infarction varies from a catastrophic event, with an acute tear leading to immediate death (acute rupture), or slow and incomplete tear leading to a late rupture ...
Kociol Robb D - - 2012
The following are highlights from Circulation: Heart Failure Topic Review. This series will summarize the most important manuscripts, as selected by the editors, that have been published in the Circulation portfolio. The objective of this series is to provide our readership with a timely comprehensive selection of important papers that ...
Aykan A C - - 2012
Ventricular septal rupture and ventricular pseudoaneurysm formation are rare complications of acute myocardial infarction. Immediate intervention is mandatory in these circumstances. Our case is a unique presentation of an anterior myocardial infarction in an 85-year-old male, complicated by ventricular septal rupture and ventricular pseudoaneurysm formation.
Daoulah Amin - - 2012
Spontaneous coronary artery dissection (SCAD) is a rare condition that can result in unstable angina, acute myocardial infarction, and sudden death. This condition may occur particularly in women during late pregnancy and in the postpartum period. We present the case of a 33-year-old African American woman, who had spontaneous left ...
Shiyovich Arthur A Internal Medicine E, Soroka University Medical Center, P.O. Box 151, 84101 Beer Sheva, - - 2012
Rupture of the free wall of the left ventricle occurs in approximately 4% of patients with infarcts and accounts for approximately 20% of the total mortality of patients with myocardial infractions. Relatively few cases are diagnosed before death. Several distinct clinical forms of ventricular free wall rupture have been identified. ...
Harries Rl R Nevill Hall Hospital, Abergavenny, - - 2012
Thrombolysis is the gold standard of treatment for acute myocardial infarction (MI), however can be associated with haemorrhagic complications. To date, splenic rupture following thrombolysis has only been reported in those with an associated history of major trauma or splenomegaly. We report a case of a 47-year old female who ...
Javaheri Shahrokh S Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA. - - 2012
Excess sudden death due to ventricular tachyarrhythmias remains a major mode of mortality in patients with systolic heart failure. The aim of this study was to determine the association of nocturnal ventricular arrhythmias in patients with low ejection fraction heart failure. We incorporated a large number of known pathophysiologic triggers ...
Fragasso Gabriele - - 2011
OBJECTIVE: To relate therapeutic issues, comorbidities and functional parameters to mortality/morbidity of mild/moderate heart failure patients. METHODS: From our heart failure clinic, 372 heart failure patients (269 men, aged 66 ± 11 years), with stable heart failure and ejection fraction 45% or less were recruited. Survival curves were estimated according to the ...
Forslund Ann-Sofie - - 2011
Aims: To describe trends in incidence, outcome, and background characteristics among people who suffered an out-of-hospital cardiac arrest with validated myocardial infarction aetiology (OHCA-V). Methods and results: People from the northern Sweden MONICA myocardial registry (1989-2007) with OHCA-V (n = 2977) were divided in two age groups (25-64 and 65-74 ...
Ceyhan Koksal - - 2011
Objectives: To determine both ventricular functions and tissue Doppler echocardiography (TDE)-derived myocardial performance index (MPI) in patients with coronary artery ectasia (CAE). Subjects and Methods: Twenty-five patients with CAE (13 men; mean age 57 ± 9 years) and 25 age- and sex-matched controls without CAE (8 men; mean age 54 ...
Kaya Mehmet G - - 2011
Elevated uric acid (UA) levels have been associated with cardiovascular disease in epidemiologic studies. The relation between UA levels and long-term outcomes in patients with ST-segment elevation myocardial infarction who undergo primary percutaneous coronary intervention is not known. Data from 2,249 consecutive patients with ST-segment elevation myocardial infarction who underwent ...
Thelle Dag Steinar - - 2011
There has been a cardiovascular revolution since the 1970s in many industrialized countries with rapidly declining mortality rates especially for coronary heart disease (CHD). This has been most striking for men. A slower decline in out-of hospital mortality for women below 55 has been demonstrated in Finland. This, and indications ...
Luepker Russell V - - 2011
Population rates of acute myocardial infarction (AMI) are changing. Consistent case definitions to evaluate these trends and make comparisons are essential. The World Health Organization (WHO) AMI diagnostic algorithm and clinical judgments were the standards for classification. However, in recent years, five new algorithms, to include diagnostic advances, are advocated ...
Ogah O S - - 2011
We sought to determine the prevalence of echocardiographically determined left ventricular systolic dysfunction in asymptomatic hypertensive subjects seen in Abeokuta, Nigeria. Echocardiography was performed in 832 consecutive hypertensive subjects referred for cardiac evaluation over a three-year period. Data were obtained in 832 subjects (50.1% women) aged 56.0 ± 12.7 years ...
Philips Binu - - 2012
We report a case of idiopathic ventricular fibrillation treated by catheter ablation of the monomorphic initiating premature beat. The initiating focus was identified using intacardiac defibrillator electrograms (EGMs).
Eitel Ingo - - 2011
BACKGROUND: -There is conflicting evidence regarding sex-based differences in myocardial salvage and clinical outcome in patients after ST-elevation myocardial infarction (STEMI). The aim of this study was to investigate whether there are gender-associated differences in infarct characteristics (myocardial salvage, infarct size, microvascular obstruction) and clinical outcome in STEMI patients reperfused ...
Ernst Michael E ME Department of Pharmacy Practice and Science, College of Pharmacy, University of Iowa, Iowa City, IA, USA. - - 2011
Chlorthalidone (CTD) reduces 24-hour blood pressure more effectively than hydrochlorothiazide (HCTZ), but whether this influences electrocardiographic left ventricular hypertrophy is uncertain. One source of comparative data is the Multiple Risk Factor Intervention Trial, which randomly assigned 8012 hypertensive men to special intervention (SI) or usual care. SI participants could use ...
Paiva Vagner Clayton de - - 2011
Several methods have been used to assess cardiac vagal modulation, but there are gaps regarding the association and accuracy of these methods. To investigate the association between three valid, reproducible and commonly methods used to assess cardiac vagal modulation and compare their accuracies. Thirty healthy men (23 ± 4 years) ...
Parikh Puja B - - 2011
BACKGROUND: The appropriateness use criteria (AUC) for the performance of transthoracic echocardiography were recently revised. The aims of this study were to evaluate the 2011 AUC for echocardiography for their ability to categorize indications not addressed by the older AUC and to identify trends in ordering unclassified and inappropriate studies ...
Martinez Joseph P - - 2012
Cardiac arrest remains a common problem throughout the world. This article explores several factors that aid in determining prognosis after cardiac arrest. It is broadly divided into prearrest factors, intra-arrest factors, and postarrest factors. Prearrest factors predominantly concern the presence or absence of a shockable rhythm. Intra-arrest factors look at ...
Dumas F - - 2012
Optimal care for out-of hospital cardiac arrest (OHCA) patients may depend on the underlying aetiology of OHCA. Specifically chest compression only bystander CPR may provide greater benefit among those with cardiac aetiology and chest compressions plus rescue breathing may provide greater benefit among those with non-cardiac aetiology. The aim of ...
Barbier Charlotte Ebeling - - 2011
The purpose of this study was to investigate the prevalence of unrecognized myocardial infarction (UMI) detected with magnetic resonance imaging (MRI) and whether it is related to cerebral ischemic lesions on MRI in an elderly population-based cohort. There is a correlation between stroke and recognized myocardial infarction (RMI) and between ...
Jespersen Lasse L Department of Cardiology, Bispebjerg University Hospital, Bispebjerg Bakke 23, 2400 Copenhagen, Denmark. - - 2012
Patients with chest pain and no obstructive coronary artery disease (CAD) are considered at low risk for cardiovascular events but evidence supporting this is scarce. We investigated the prognostic implications of stable angina pectoris in relation to the presence and degree of CAD with no obstructive CAD in focus. We ...
Perk Gila - - 2011
Atrial fibrillation is a common, clinically significant arrhythmic disorder that results in increased risk of morbidity and mortality in affected patients. Atrial fibrillation is more prevalent among men compared with women and the risk for developing atrial fibrillation increases with advancing age. Ischaemic stroke is the most common clinical manifestation ...
Hu Xiaorong - - 2011
Endogenous testosterone has been shown to provide a protective role in the development of cardiovascular diseases in men. This study investigated the changes of testosterone level and its relationship to the severity of coronary artery stenosis in middle-aged men with coronary artery disease (CAD). Serum testosterone concentration was measured in ...
Galdas Paul M - - 2011
Objective. To describe how culture underlies Canadian Punjabi Sikh men's experiences of adopting lifestyle changes following myocardial infarction (MI). Design. Qualitative, interpretive design. In-depth, individual interviews were conducted with 27 Canadian Punjabi Sikh men post-MI. Data were analysed using constant comparative methods. Results. Cultural influences were identified in Punjabi Sikh ...
Colossimo Ana P - - 2011
BACKGROUND: Several factors are known to interfere with electrocardiogram (ECG) sensitivity when diagnosing Left Ventricular Hypertrophy (LVH), with gender and cardiac mass being two of the most important ones OBJECTIVE: To evaluate the influence of gender on the sensitivity of some of the criteria used to detect LVH, according to ...
Francis Gary S - - 2011
For nearly three decades, starting in the early 1970s, the cardiology research laboratories at the University of Minnesota served as the focal point for the discovery and implementation of much of the information we now apply to the management of heart failure. Director Jay Cohn, building on his expertise in ...
Kothawade Kamlesh - - 2011
Women exhibit a greater symptom burden, more functional disability, and a higher prevalence of no obstructive coronary artery disease compared to men when evaluated for signs and symptoms of myocardial ischemia. Microvascular coronary dysfunction (MCD), defined as limited coronary flow reserve and/or coronary endothelial dysfunction, is the predominant etiologic mechanism ...
Shah Amil M - - 2011
OBJECTIVES: Our objective was to define the relationship between renal dysfunction - both albuminuria and reduced estimated glomerular filtration rate (eGFR) - and cardiac structure and diastolic dysfunction among patients with chronic hypertension. METHODS: Both albuminuria and eGFR were measured in 540 asymptomatic patients with hypertension and diastolic dysfunction assessed ...
Haraki Tatsuo - - 2011
A 68-year-old man with acute ST elevation myocardial infarction (STEMI) underwent emergent coronary angiography which showed total occlusion in the proximal right coronary artery (RCA). Gray-scale intravascular ultrasound (IVUS) revealed the culprit lesion was expansively remodeled and contained ruptured and echolucent plaques with spotty calcification, whereas thin-capped fibroatheroma and a ...
Torres H J - - 2011
Cardiac allograft vasculopathy (CAV) is a major factor limiting long-term survival after heart transplantation (HT). The purpose of this study was to characterize the coronary artery structure and to determine the prevalence of vasculopathy after HT, comparing the sensitivity of coronary angiography with that of intravascular ultrasound (IVUS) and virtual ...
Cicek Davran D Department of - - 2011
Ventricular septal rupture (VSR) complicating acute myocardial infarction (AMI) is a serious clinical problem with high mortality rate due to cardiogenic shock or prolonged hemodynamic compromise. Despite multiple improvements in medical, interventional and surgical techniques, early and long-term prognosis after AMI related VSR still remain unpromising. We report a patient ...
Genovesi Dario - - 2011
PURPOSE: In clinical myocardial single photon emission computed tomography (SPECT), attenuation artefacts may cause a loss of specificity in the identification of diseased vessels that can be corrected by means of gated SPECT (GSPECT) acquisition or CT attenuation correction (AC). The purpose of this multicentre study was to assess the ...
Watanabe Kenichi - - 2011
Autoimmune responses and inflammation are involved in the pathogenesis of many cardiovascular diseases. There is compelling evidence that inflammatory mechanisms may contribute to progressive heart failure. Thus, myocardial infiltration of lymphocytes and mononuclear cells, increased expression of pro-inflammatory chemokines and cytokines and circulating autoantibodies are frequently observed in myocarditis and ...
Conte Maria Rosa - - 2011
Cardiac magnetic resonance (CMR) imaging with late gadolinium enhancement (LGE) can identify areas of myocardial fibrosis in vivo in patients with hypertrophic cardiomyopathy (HCM). The aim of this study was to examine the association between clinical-morphological variables, risk factor for sudden death, and LGE findings in a consecutive, unselected population ...
Bouzas-Mosquera Alberto - - 2011
Limited data are available on the relation between left atrial size and outcome among patients referred for clinically indicated echocardiograms. Our aim was to assess the association of left atrial size with all-cause mortality and ischemic stroke in a large cohort of patients referred for echocardiography. Left atrial diameter was ...
Bergman Eva - - 2011
The aim of this study was to assess changes in the sense of coherence of patients who had suffered their first myocardial infarction. Out of 100 patients at the start of the study, these changes were evaluated in 66 men and 18 women aged 36-70 years. Generally, the sense of coherence ...
Wijnmaalen Adrianus P - - 2011
A left bundle-branch block (LBBB)-like pattern with a dominant S-wave in V(1) is common in idiopathic ventricular arrhythmias (VA). Discrimination between idiopathic and scar-related LBBB pattern VA has important clinical implications. We hypothesized that the VA QRS morphology is influenced by the presence of ventricular scar, allowing ECG discrimination of ...
Wang Wei-Jian - - 2011
Ventricular assist devices may function as a bridge to recovery or heart transplantation, however, little is known about its mechanisms. This study examined the role of matrix metalloproteinases (MMP)-tissue inhibitors of metalloproteinases (TIMP) axis in the process of recovery after unloading in a rat ischemic-induce heart failure (HF) model. Myocardial ...
Hu Xiaorong - - 2011
High mobility group box 1 protein (HMGB1) plays an important role in myocardial ischemia and reperfusion (I/R) injury. Ethyl pyruvate (EP), a potent reactive oxygen species scavenger, has been reported to inhibit myocardial apoptosis and reduce myocardial I/R injury. The aim of this study was to investigate the mechanism by ...
Hedhli Nadia N Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, - - 2011
Removal of cardiac endothelial cells (EC) has been shown to produce significant detrimental effects on the function of adjacent cardiac myocytes, suggesting that EC play a critical role in autocrine/paracrine regulation of the heart. Despite this important observation, the mediators of the protective function of EC remain obscure. Neuregulin (NRG, ...
Li Xu-Yong - - 2011
Many studies have examined the association between coffee consumption and risk of cardiovascular disease, but the results still remain controversial. Caffeine is one of the main biologically active compounds of coffee. The aim of this study was to investigate the potential role of caffeine on myocardial ischemia/reperfusion (I/R) injury in ...
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