Search Results
Results 201 - 250 of 1513
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Lu Zhibing - - 2009
Previous studies showed that autonomic activation by high-frequency electrical stimulation (HFS) during myocardial refractoriness evokes rapid firing from pulmonary vein (PV) and atria, both in vitro and in vivo. This study sought to investigate the autonomic mechanism underlying the rapid firings at various sites by systematic ablation of multiple ganglionated ...
Saczynski Jane S - - 2009
Atrial fibrillation (AF) is a common complication of acute myocardial infarction (AMI) and this arrhythmia is associated with increased morbidity and mortality in patients with AMI. Limited information is available, however, about changing, and contemporary, trends in the incidence and death rates associated with AF complicating AMI. We examined the ...
Barra Silvia - - 2009
Atrial fibrillation (AF) is the most common sustained arrhythmia. While antiarrhythmic agents and electrical cardioversion are highly effective in restoring sinus rhythm, the results obtained in prevention of recurrences are disappointing. Recently, angiotensin II has been recognized as a key factor in atrial structural and electrical remodeling associated with AF. ...
Burashnikov Alexander A Research Scientist Masonic Medical Research Laboratory, 2150 Bleecker Street, Utica, NY 13501, - - 2009
The pharmacological approach to therapy of atrial fibrillation (AF) is often associated with adverse effects resulting in the development of ventricular arrhythmias. As a consequence, much of the focus in recent years has been on development of atrial-selective agents. Atrial-selective sodium channel blockers have recently been shown to exist and ...
Tong Haiyan - - 2009
Engineered carbon nanotubes are being developed for a wide range of industrial and medical applications. Because of their unique properties, nanotubes can impose potentially toxic effects, particularly if they have been modified to express functionally reactive chemical groups on their surface. The present study was designed to evaluate whether acid ...
Gillis Anne M - - 2009
AIMS: Selective atrial pacing algorithms have been developed for prevention of atrial tachycardia/atrial fibrillation (AT/AF). Although short-term studies have shown modest to minimal incremental benefit of these algorithms compared with conventional dual-chamber (DDD/R) pacing for prevention of AT/AF, the long-term effects of these algorithms are unknown. Accordingly, we compared atrial ...
Wasywich C A - - 2010
Heart failure (HF) and atrial fibrillation (AF) are common, associated with significant morbidity and mortality, and frequently coexist. It is uncertain from published data if the presence of AF in patients with HF is associated with an incremental adverse outcome. The aim of this study was to combine the results ...
Nieuwlaat Robby - - 2009
OBJECTIVES: Our aim was to identify shortcomings in the management of patients with both atrial fibrillation (AF) and heart failure (HF). BACKGROUND: AF and HF often coincide in cardiology practice, and they are known to worsen each other's prognosis, but little is known about the quality of care of this ...
Postma Alex V - - 2009
Atrial fibrillation (AF) is the most common cardiac arrhythmia encountered in clinical practice. The abnormal rhythm is associated not only with a variety of symptoms, such as palpitations, dizziness, or shortness of breath, but also with increased risk of stroke, heart failure, and mortality. A genetic predisposition is suggested by ...
Crandall Mark A - - 2009
BACKGROUND: Inflammation has been shown to have a direct role in the initiation, maintenance, and recurrence of atrial fibrillation (AF) although the underlying mechanisms are unknown. Similarly, it is unclear if inflammatory markers are elevated due to the AF alone or the coexisting cardiovascular diseases that increase the risk of ...
Berton G - - 2009
AIMS: Atrial fibrillation/flutter (AF/FL) is a common complication of acute myocardial infarction (AMI). Indeed, the determinants of AF/FL in AMI-patients and the association of AF/FL with mortality are not well-known. The purpose of the present study was to investigate the relationship between presence of AF/FL and mortality in patients with ...
Chang Jae Hong JH Departments of Neurology College of Medicine, Korea University, Seoul, - - 2009
Generalized chorea caused by unilateral cerebral infarction has rarely been reported. A 58-year-old woman presented involuntary movement in her all extremities after acute cerebral infarction on her right anterior cerebral artery territory. The involuntary movements were diagnosed as generalized chorea. We didn't find any cause of generalized chorea except the ...
Niu Guodong - - 2009
BACKGROUND: The objective of this study was to develop an acute experimental model showing both focal and macroreentrant sustained atrial fibrillation (AF). METHODS AND RESULTS: In 31 anesthetized dogs, bilateral thoracotomies allowed the attachment of electrode catheters at the right and left superior pulmonary veins, atrial free walls, and atrial ...
Yamada Takumi - - 2010
A 60-year-old woman was referred for catheter ablation of atrial fibrillation (AF). Atrial flutter and atrial tachycardia (AT) also had been clinically documented. During the electrophysiological study, the clinical AT was induced by burst atrial pacing during isoproterenol infusion and exhibited negative P waves in the inferior leads, positive P ...
Choi Jin-Oh - - 2009
We investigated whether the echocardiographic parameters of the left atrium (LA) can predict the development of nonvalvular atrial fibrillation (AF). Among 14,062 patients (>20 years old) who underwent an echocardiographic examination were evaluated, 2,606 patients who underwent follow-up ECG with an interval of >6 months were investigated. Newly developed AF ...
Friedman Paul A - - 2009
BACKGROUND: Pharmacologic therapies to prevent stroke in atrial fibrillation (AF) have numerous limitations, prompting the development of device-based therapies. We investigated whether an electrogram-based approach using a novel hollow suture can safely capture and ligate the left atrial appendage (LAA). METHODS AND RESULTS: A novel system for closure of the ...
Bourke T - - 2009
Atrial fibrillation (AF) and congestive heart failure (CHF) are commonly encountered together, either condition predisposing to the other. The presence of each condition increases the morbidity and mortality associated with the other and their coexistence complicates patient management. Common risk factors include age, hypertension, diabetes mellitus and coronary artery disease. ...
Mulder D J - - 2009
BACKGROUND.: ST-elevation myocardial infarction (STEMI) is associated with increased inflammation and oxidative stress, enhancing the formation of advanced glycation endproducts (AGEs). These encompass a characteristic fluorescence pattern, which can be non-invasively measured as skin autofluorescence (AF). In this study we investigate whether skin AF is elevated in STEMI, its association ...
Tsai Wei-Chung - - 2009
Inducible atrioventricular nodal reentrant tachycardia was demonstrated by electrophysiological studies in a 55-year-old female who suffered from intermittent palpitation, in which paroxysmal atrial fibrillation (AF) was consistently documented by electrocardiogram recordings. After ablation of the slow pathway, the atrioventricular nodal reentrant tachycardia and AF were not inducible. During 2 years ...
Roberts-Thomson Kurt C - - 2009
BACKGROUND: Information regarding left atrial (LA) substrate in conditions predisposing to atrial fibrillation (AF) is limited. OBJECTIVE: This study sought to characterize the left atrial remodeling that results from chronic atrial stretch caused by atrial septal defect (ASD). METHODS: Eleven patients with hemodynamically significant ASDs and 12 control subjects were ...
Turgut Okan - - 2010
P wave dispersion (PWD) is defined as the difference between maximum P wave duration (Pmax) and minimum P wave duration recorded from multiple surface electrocardiogram (ECG) leads. An increase in PWD indicates heterogeneous intraatrial and interatrial conduction and discontinuous anisotropic propagation of sinus impulses, providing a substrate that favors reentry ...
Weerasooriya Rukshen - - 2009
Atrial tachycardias represent the second front of atrial fibrillation (AF) ablation. They are frequently encountered during the index ablation for patients with persistent AF and are common following ablation of persistent AF, occurring in half of all patients who have had AF successfully terminated. An atrial tachycardia is rightly seen ...
Liu Tong - - 2010
Atrial fibrillation (AF) represents the most common sustained arrhythmia in clinical practice. Recent studies have demonstrated the possible implication of inflammation and oxidative stress in the pathogenesis of AF. Probucol, a lipid-lowering drug that has a potent antioxidant effect, may have favorably benefits on atrial remodeling in AF. Although succinobucol, ...
Krummen David E - - 2009
Understanding of the mechanisms underlying atrial fibrillation (AF) remain limited. However, both persistent and paroxysmal AF likely initiate via the interaction of triggers such as premature atrial beats with 'substrate', that includes static components such as fibrosis and scar, as well as dynamic alterations that may include the rate-response of ...
Lin Tung-Chao - - 2009
Coronary embolism with acute myocardial infarction (MI) following direct-current (DC) cardioversion of atrial fibrillation (AF) has rarely been reported. We present the case of a 34-year-old female with severe aortic regurgitation and highly symptomatic paroxysmal AF. Acute embolic MI occurred 4 days after DC cardioversion of AF, although there was ...
Ravi Krishna C KC University of California and Veterans Affairs Medical Center, San Diego, California 92161, - - 2009
Differences in atrial fibrillation (AF) cycle length (CL) between the left (LA) and right (RA) atrium and coronary sinus (CS) may help separate paroxysmal from persistent AF and identify patients most likely to respond to pulmonary vein isolation, but has not been measured noninvasively. We developed methods to estimate regional ...
Benchimol-Barbosa P R - - 2009
Atrial fibrillation (AF) affects subjects with Chagas' disease and is an indicator of poor prognosis. We investigated clinical, echocardiographic and electrocardiographic variables of Chagas' disease in a long-term longitudinal study as predictors of a new-onset AF episode lasting >24 h, nonfatal embolic stroke and cardiac death. Fifty adult outpatients (34 ...
Kumar Kapil - - 2009
INTRODUCTION: In vitro studies and ambulatory ECG recordings from the MERLIN TIMI-36 clinical trial suggest that the novel antianginal agent ranolazine may have the potential to suppress atrial arrhythmias. However, there are no reports of effects of ranolazine on atrial electrophysiologic properties in large intact animals. METHODS AND RESULTS: In ...
Aldhoon B - - 2010
Although atrial fibrillation (AF) is the most common cardiac arrhythmia in clinical practice, precise mechanisms that lead to the onset and persistence of AF have not completely been elucidated. Over the last decade, outstanding progress has been made in understanding the complex pathophysiology of AF. The key role of ectopic ...
Rossman Eric I - - 2009
Gap junction uncoupling can alter conduction pathways and promote cardiac re-entry mechanisms that potentiate many supraventricular arrhythmias, such as atrial fibrillation (AF) and atrial flutter (AFL). Our objective was to determine whether GAP-134 [(2S,4R)-1-(2-aminoacetyl)-4-benzamido-pyrrolidine-2-carboxylic acid], a small dipeptide gap junction modifier, can improve conduction and ultimately prevent AF/AFL. In rat ...
Smelley Matthew P - - 2009
The incidence of persistent and permanent AF will likely continue to increase as the population ages and as patients with structural heart disease live longer. Many catheter-based ablation techniques have been developed to treat AF. This paper will review which of these approaches have been demonstrated to be effective for ...
Friedlander Arthur H - - 2009
BACKGROUND: Atrial fibrillation (AF) is a cardiac rhythm disturbance arising from disorganized electrical activity in the atria, and it is accompanied by an irregular and often rapid ventricular response. It is the most common clinically significant dysrhythmia in the general and older population. TYPES OF STUDIES REVIEWED: The authors conducted ...
Kalahasty Gautham - - 2009
This article reviews the wide range of implantable device-based therapies (mainly pacemakers) that are being used in the management of atrial fibrillation (AF), atrial flutter, and atrial tachycardia. The role of pacemakers in the management of patients with AF and in the prevention of AF has been extensively studied. Based ...
Saltman Adam E - - 2009
For cardiac surgery patients presenting with atrial fibrillation (AF), surgeons offer an operation that corrects the structural heart disease and the AF. With this approach, it is estimated that surgeons will perform more than 10,000 ablation procedures in 2008. Surgeons are developing minimally invasive techniques for stand-alone, epicardial ablation of ...
Boyle Noel G NG UCLA Cardiac Arrhythmia Center, Division of Cardiology, Department of Medicine, BH 407 CHS, David Geffen School of Medicine at UCLA, 10833 Le Conte Avenue, Los Angeles, CA 90095-1679, USA. - - 2009
Atrial fibrillation (AF) and congestive heart failure are common conditions and each predisposes to the development of the other. Basic research using animal models of the two conditions continues to yield insights that may improve therapies. The role of medical therapies aimed at the underlying structural changes in AF continues ...
Aidonidis Isaac - - 2009
OBJECTIVES: Progressive electrical alternans followed by conduction block and fibrillatory conduction have been suggested to precede disorganization of atrial flutter (Afl) to atrial fibrillation (AF). The purpose of the present study was to investigate patterns of local repolarization in the high and low right atrium to determine the site with ...
Sakhuja Rahul - - 2009
Atrial fibrillation (AF) is common in patients who have implantable defibrillators and presents some unique challenges and opportunities. AF burden can be assessed more accurately, allowing for evaluation of therapy efficacy (drugs or ablation). It remains to be shown whether home monitoring of defibrillators to detect and treat AF more ...
Lehto Mika - - 2009
BACKGROUND: Atrial fibrillation (AF) causes electrical, functional, and structural changes in the atria. We examined electrophysiologic remodeling caused by AF and its reversal noninvasively by applying a new atrial signal analysis based on magnetocardiography (MCG). METHODS: In 26 patients with persistent AF, MCG, signal-averaged electrocardiography (SAECG), and echocardiography were performed ...
Cianfrocca Cinzia - - 2010
The association between inflammatory status and thrombosis in patients with atrial fibrillation (AF) is unclear. We studied the correlation between inflammation and the risk of thrombogenesis in patients with AF and the relationship of inflammation with other factors associated with thrombotic risk. We studied 150 consecutive patients (69 men, age ...
Takagi Yasuhiro - - 2009
There is increasing evidence that left atrial (LA) size is an important predictor of adverse cardiovascular outcomes such as atrial fibrillation, stroke, and congestive heart failure. The aim of this study was to determine whether there is a difference in results of quantification of LA volume by the area-length and ...
Udyavar Ameya R - - 2009
INTRODUCTION: The left atrial (LA) substrate plays an important role in the maintenance of atrial fibrillation (AF). However, little is known about the acute effect of circumferential pulmonary vein isolation (CPVI). This study was to investigate the acute change of LA activation, voltage and P wave in surface electrocardiogram (ECG) ...
Ryu Kyungmoo - - 2009
Studies of atrial fibrillation (AF) have demonstrated that a stable rhythm of very short cycle length in the left atrium (LA) can cause fibrillatory conduction in the rest of the atria. We tested the hypothesis that fast Fourier transform (FFT) analysis of atrial electrograms (AEGs) during this AF will rapidly ...
Belluzzi Fabio - - 2009
OBJECTIVES: The aim of the present study was to verify whether angiotensin-II converting enzyme (ACE) inhibition is also effective in preventing relapses of lone atrial fibrillation (LAF), that is, in the absence of hypertension and/or heart disease. BACKGROUND: Several studies have shown that ACE inhibitors are effective in preventing atrial ...
Bielecka-Dabrowa Agata - - 2009
Atrial fibrillation (AF) is a complex condition with several possible contributing factors. The rapid and irregular heartbeat produced by AF increases the risk of blood clot formation inside the heart. These clots may eventually become dislodged, causing embolism, stroke and other disorders. AF occurs in up to 15% of patients ...
Kaireviciute D - - 2009
Atrial fibrillation (AF) following cardiac surgery is a common complication, which increases incidence of other complications, hospital and healthcare costs. The reported rate of the occurrence of postoperative AF varies with different studies, depending on population profile, type of surgery, arrhythmia definition and detection methods, design of study. Nonetheless, the ...
Sciagrà Roberto R Nuclear Medicine Unit, Department of Clinical Physiopathology, University of Florence, Viale Morgagni 85, 50134, Florence, Italy. - - 2009
Atrial fibrillation (AF) and coronary microvascular dysfunction (CMD) are common in hypertrophic cardiomyopathy (HCM), but whether they are associated is unclear. We assessed the relationship between AF and CMD in HCM. Global hyperemic myocardial blood flow (hMBF) was measured in 95 HCM patients (16 with, 79 without paroxysmal or chronic ...
Crossley George H - - 2009
BACKGROUND: Atrial fibrillation (AF) is a major cause of morbidity and mortality, especially in patients with congestive heart failure. OBJECTIVES: The purposes of this international, prospective multicenter study were to evaluate the efficacy of atrial shock therapy in patients with a cardiac resynchronization therapy defibrillator (CRT-D) and to evaluate the ...
Babarro Eva González - - 2009
Cardioembolic stroke accounts for one third of all ischemic strokes, and atrial fibrillation (AF) is the cardiac source of emboli in 50% of them. However, the absolute risk of stroke associated with AF has enormous variability, and several clinical risk stratification schemes have been proposed. One of the most validated ...
Larned Joshua M - - 2009
Atrial fibrillation (AF) is the most common arrhythmia in congestive heart failure (HF) and indicates a worse prognosis. AF increases HF symptoms and increases in prevalence with increasing New York Heart Association class. AF also interferes with the ideal management of HF. Across all HF etiologies, AF may be a ...
Naccarelli Gerald V - - 2009
Atrial fibrillation (AF) is the most common form of cardiac arrhythmia and is associated with an increased risk of cardiovascular morbidity and mortality, especially due to ischemic stroke. The occurrence of AF leads to atrial electrical and structural remodeling. The renin-angiotensin system appears to play a role in the development ...
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