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Lumens Joost - - 2012
AIMS: In chronic pulmonary hypertension (PH), right ventricular (RV) failure is associated with shortening of the RV free wall (RVFW) beyond pulmonary valve closure temporarily paralleled by pronounced lengthening of the left ventricular free wall (LVFW). We hypothesized that this early-diastolic LVFW lengthening is caused by altered RVFW myofibre function ...
Guazzi Marco - - 2012
In heart failure (HF) syndrome, the development of pulmonary hypertension (PH), right ventricular (RV) dysfunction and failure are ominous prognostic signs. Pathophysiology, clinical interest and targeted therapeutic approaches for left-sided PH and its consequences on RV function have been traditionally confined to advanced HF stages. Community- and population-based studies have ...
Ch'ng Stephanie - - 2012
Most cases of blunt cardiac rupture (BCR) are associated with mortality at the scene of the injury. For the fortunate 13% to 17% of patients who survive the journey to the hospital, the treatment is definitive surgical repair. In the setting of previous sternotomy, the pericardial adhesions may limit the ...
Rich Jonathan D - - 2012
BACKGROUND: In rodent models of pulmonary hypertension (PH) and right ventricular hypertrophy (RVH), the QTc interval is prolonged, reflecting downregulation of repolarizing Kv channels in RV myocytes. The significance of QTc prolongation in human PH is unknown. We hypothesized that QTc prolongation occurs in human PH, is associated with RVH ...
Gladwin Mark T MT Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh, 3459 Fifth Avenue, Montefiore Hospital, Pittsburgh, PA 15213, USA. - - 2012
Sickle cell disease is characterized by recurrent episodes of ischemia-reperfusion injury to multiple vital organ systems and a chronic hemolytic anemia, both contributing to progressive organ dysfunction. The introduction of treatments that induce protective fetal hemoglobin and reduce infectious complications has greatly prolonged survival. However, with increased longevity, cardiovascular complications ...
Rosenberg Mark - - 2012
Eur J Clin Invest 2012 ABSTRACT: Background  Osteopontin (OPN) was found upregulated in several heart failure models and appears to play an important role in myocardial remodelling. As we have previously demonstrated that OPN predicts mortality in patients with pulmonary hypertension (PH), we now evaluated whether OPN also predicts adverse ...
Sato Takahiro - - 2012
The accuracy of echocardiographic parameters of right ventricular (RV) function has not been sufficiently validated in patients with pulmonary hypertension (PH). The aim of this study was to evaluate whether echocardiographic measurements reliably reflect RV systolic function in PH using cardiac magnetic resonance imaging (CMRI)-derived RV ejection fraction (RVEF) as ...
Anselmino Matteo - - 2012
Transcatheter atrial fibrillation ablation has undergone an impetuous advance over the past decades, reaching satisfactory results concerning safety and medium-term efficacy. Several experimental studies have paved the way both to new ablative procedures and technologies development. The present work reviews the history of transcatheter atrial fibrillation ablation, offering a wide ...
Rottlaender Dennis - - 2012
Pulmonary hypertension (PH) is associated with progressive impairment of right ventricular function, reduced exercise capacity and a poor prognosis. Little is known about the prevalence, clinical manifestation and impact of atrial fibrillation (AF) on cardiac function in PH. In a four year single-centre retrospective analysis 225 patients with confirmed PH ...
Leary Peter J PJ University of Washington, Division of Pulmonary and Critical Care, Seattle, Washington, - - 2012
Right ventricular (RV) failure is a key determinant of morbidity and mortality in pulmonary hypertension (PH). The present study aims to add to existing descriptions of RV structural and functional changes in PH through a comprehensive three-dimensional (3D) shape analysis. We performed 3D echocardiography on 53 subjects with PH and ...
Komarov Denis A - - 2012
A new low-field electron paramagnetic resonance approach for noninvasive measurements of myocardial oxygen tension and tissue acidity was developed. The approach was applied to monitor myocardial pO(2) and pH in a model of global no-flow ischemia (30 min) and reperfusion in isolated perfused rat hearts. The myocardial oxygen measurements were ...
Zègre Hemsey Jessica K - - 2011
INTRODUCTION: The American Heart Association and other scientific guidelines recommend emergency medical services acquire prehospital (PH) electrocardiography (ECG) in all patients with symptoms of acute coronary syndrome. The purpose of this article is to critically review the scientific literature about PH ECG. METHODS: Using multiple search terms, we searched the ...
Zègre Hemsey Jessica K JK School of Nursing, University of California, San Francisco, CA, USA. - - 2012
We studied 620 patients who activated "911" for chest pain symptoms to determine the sensitivity and specificity of 12-lead electrocardiogram (ECG) ST-segment monitoring in the prehospital period (PH ECG) for diagnosing acute coronary syndrome (ACS) and to assess whether the addition of PH ECG signs of ischemia/injury to the initial ...
Schotola Hanna - - 2011
The postoperative course after major surgical procedures such as cardiothoracic operations is often accompanied by acute metabolic abnormalities due to large volume and temperature shifts. In general, those intervention-induced trauma might cause the use of catecholamines to stabilize hemodynamics. Within the cardiac community, there are still controversial discussions about standardized ...
Davarpanah Amir H - - 2011
The purpose of this study was to investigate the utility of bolus-triggering data from pulmonary CT angiography for predicting the diagnosis of pulmonary hypertension (PH) and right ventricular dysfunction (RVD) and to test its performance against previously established CT signs of PH. Automated bolus-triggering data from pulmonary CT angiograms of ...
Vogel-Claussen Jens - - 2011
: To prospectively evaluate the cardiac magnetic resonance (MR) imaging-derived measurement of right ventricular (RV) septomarginal trabeculation (SMT) mass as a noninvasive marker for pulmonary hypertension (PH), compared with the ventricular mass index (VMI = RV mass/left ventricular mass) and RV mass. : A total of 49 patients (60 ± ...
Cua Clifford L - - 2011
Cardiac resynchronization therapy is increasingly being used in the paediatric population as a tool for managing patients with heart failure. Various non-invasive parameters have been used to optimize the settings on the biventricular pacemaker. We describe implantation of a biventricular pacemaker in a nineteen-month-old child because of intractable heart failure. ...
Nollo Giandomenico - - 2011
The effect on acid-base balance efficacy of intermittent warm and cold blood cardioplegia (IWBC, ICBC) was assessed in 44 patients who underwent cardiac surgery with prolonged aortic cross clamping. With this purpose a customized multi sensor probe was inserted in the coronary sinus, and pH, PO(2), PCO(2) and temperature were ...
Fukuda Yuko - - 2011
BACKGROUND: The objectives of this study were to test the utility of right ventricular (RV) speckle-tracking strain as an assessment tool for RV function in patients with pulmonary hypertension (PH) compared with conventional echocardiographic parameters and to investigate the relationship of the findings obtained with RV speckle-tracking strain with the ...
Cikirikcioglu M - - 2011
Primary cardiac lymphomas (PCL) are extremely rare, and diffuse large B-cell lymphoma is a highly aggressive subtype. We report a case that was initially diagnosed as chronic right heart dysfunction. Detailed investigations revealed a large lobulated tumour occluding the right atrium, infiltrating the inter-atrial septum, the roof of the left ...
Nascimento Bruno Ramos - - 2011
Noncompaction of ventricular myocardium (NVM) is a rare cardiomyopathy, most probably caused by disturbances in embryonic morphogenesis of the myocytes, resulting in prominent trabeculations in the ventricular myocardium . Several diagnostic criteria have been proposed by echocardiography, and its association with other heart diseases is common. Its mortality is closely ...
Kenny Damien - - 2011
With advancement in transcatheter technology, numerous non-congenital structural heart lesions previously untreated, or treated with surgery are now amenable to transcatheter therapy. These therapies have centered on transcatheter valve replacement, however, other lesions are increasingly treated via the percutaneous approach. These procedures include patent foramen ovale closure, left atrial appendage ...
Pott Christian - - 2011
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited arrhythmogenic disease that can cause sudden cardiac death due to ventricular fibrillation (VF). While pharmacological therapy with beta-blockers and/or Ca(2)(+) antagonists is often unreliable, a recent study has demonstrated that flecainide can effectively suppress arrhythmia in a murine model of CPVT as ...
Ambrose Marietta S - - 2011
Advancements in computed tomography (CT) technology have revolutionized clinical practice, particularly regarding the noninvasive assessment of coronary artery disease (CAD). The versatility of cardiac CT has rendered multiple applications including assessment of cardiac structure and function, myocardial viability, and coronary anatomy. The merits of cardiac computed tomography angiography (CTA) have ...
Gul Enes E - - 2011
The electrocardiogram (ECG) has being used for decades as a reliable and inexpensive tool to diagnose acute myocardial infarction (AMI). ECG diagnosis of an occluded coronary artery is of the utmost importance. We present the case of a 46 year-old man admitted to our hospital for inferior AMI. The ECG ...
Dorfman Todd A - - 2011
The interventricular septum constitutes approximately one-third of the mass of the left ventricle, and the bulk of the anterior septum is supplied by septal branches of the left anterior descending coronary artery. Ischemia of the interventricular septum results in angina, infarction, biventricular failure and ventricular arrhythmias. While the majority of ...
Kuthe Sachin A - - 2011
We report a case of an elderly man who suffered an acute myocardial infarction (MI) with the complication of a post-MI ventricular septal defect (VSD). Situs inversus with dextrocardia was diagnosed during the course of hospitalization. Total myocardial revascularization was achieved using saphenous vein conduits. The VSD was approached through ...
Adamu G U - - 2010
Systemic hypertension is a common cause of left ventricular diastolic dysfunction. However, its prevalence in Nigerians with untreated systemic hypertension is unknown. To determine the prevalence of left ventricular diastolic dysfunction in newly diagnosed Nigerians with systemic hypertension using Doppler transmitral inflow and pulmonary venous flow velocities. Two-dimensional echocardiography including ...
Ho Kay Woon - - 2010
INTRODUCTION: A retrospective case series of acute anterior myocardial infarction (MI) patients complicated by complete atrioventricular block (AVB) treated with acute percutaneous transluminal coronary angioplasty (PTCA). CLINICAL PICTURE: Eight patients with anterior MI and complete AVB underwent acute PTCA between 2000 and 2005. Mean onset of complete AVB was 16.6 ...
Makkuni Premraj - - 2010
Left ventricular outpouchings are increasingly detected on cardiovascular imaging. Herein, we describe the case of a 45-year-old man who underwent noncardiac preoperative imaging and was found to have an asymptomatic left ventricular outpouching. The patient underwent successful surgical repair of the structure. When left ventricular outpouchings are detected, the main ...
Le Bao H - - 2010
For the treatment of refractory left atrial tachyarrhythmias, including atrial fibrillation, transseptal catheterization is often performed in order to achieve pulmonary vein isolation and left atrial substrate ablation. Herein, we report an unexpected ST-segment elevation in a 71-year-old man during a Brockenbrough transseptal catheterization procedure for atrial fibrillation ablation. The ...
Kaestner Sabine - - 2010
BACKGROUND: The most widely studied variation at the cholesteryl ester transfer protein (CETP) gene locus is a silent base change called the Thermobius aquaticus IB (TaqIB) polymorphism. TaqIB has been shown to affect levels/activity of CETP, plasma levels of high-density lipoprotein cholesterol (HDL-C), and to contribute to the risk of ...
Fard-Esfahani Armaghan A Research Institute for Nuclear Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, - - 2009
We studied the value of myocardial perfusion imaging (MPI) for the evaluation of improvement in myocardial perfusion in patients with successful percutaneous transluminal coronary angioplasty (PTCA). Sixty patients (10 women, 50 men) aged 54.18 +/- 11.71 years were analyzed. MPI was performed before PTCA, 6-10 days (16 cases), 1-3 months ...
Aydinlar Ali - - 2009
The aim of the study was to analyse parameters reflecting the sympathovagal control of ventricular depolarisation and repolarisation [heart rate variability (HRV) and QT interval dispersion (QTd)] in patients undergoing elective percutaneous transluminal coronary angioplasty (PTCA), and determine whether HRV correlates with QT dispersion parameters. The study consisted of 26 ...
Trikalinos Thomas A TA Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, - - 2009
Over the past 20 years, percutaneous transluminal balloon coronary angioplasty (PTCA), bare-metal stents (BMS), and drug-eluting stents (DES) succeeded each other as catheter-based treatments for coronary artery disease. We undertook a systematic overview of randomised trials comparing these interventions with each other and with medical therapy in patients with non-acute ...
Klug Gert - - 2009
PURPOSE: To assess with cardiac magnetic resonance imaging (CMR) the relationship between treatment delay and improvement of regional left ventricular function after primary percutaneous transluminal coronary angioplasty (p-PTCA) for acute myocardial infarction (AMI). MATERIALS AND METHODS: We performed cine- and late-enhancement (LE) CMR in 40 patients with first AMI after ...
Correa Raul - - 2009
In the present work, we have studied dynamic changes of QRS loop in the Vectocardiogram (VCG) of 80 patients that underwent Percutaneous Transluminal Coronary Angioplasty (PTCA). The VCG was obtained for each patient using the XYZ orthogonal leads of their electrocardiographic (ECG) records acquired before, during and after PTCA procedure. ...
D'Andrea Antonello - - 2009
BACKGROUND: Several reports suggest that noninvasive measurements of coronary flow reserve (CFR) by use of echocardiography may support decision making in intermediate stenosis of the left anterior descending coronary artery (LAD). The aim of the present study was therefore to analyze the clinical outcome in patients with intermediate stenosis of ...
Faulkner K - - 2008
There have been significant advances in interventional cardiology in recent years that have resulted in an increase in the frequency of both diagnostic and therapeutic X-ray-guided procedures. The number of coronary angiograms, percutaneous transluminal coronary angioplasties (PTCAs) and coronary stent procedures, as well as pacemaker insertions, has increased across Europe. ...
Basu Jayasree - - 2008
The authors examine trends over 1997-2001 in racial or ethnic disparities in the utilization of three costly, referral-sensitive procedures among the elderly-coronary artery bypass grafting (CABG), percutaneous transluminal coronary angioplasty (PTCA), and hip/joint replacement. Using a multivariate framework, they undertake a simultaneous examination of the relationships between patient, local area ...
Stewart Bruce G - - 2008
OBJECTIVE: The objective of our study was to describe the imaging features and success rate of percutaneously treated infected hepatic infarctions. MATERIALS AND METHODS: Three hundred ninety-two patients had percutaneous liver abscess aspiration and drainage or aspiration and intraoperative débridement at our institution between 1990 and 2003. One hundred fifty-one ...
Lippi Bruni Matteo - - 2008
We analyse referral patterns for patients undergoing percutaneous transluminal coronary angioplasty (PTCA) in the Emilia Romagna region of Italy, a procedure for which the assumption of a negative association between volume and adverse outcomes is used to justify its territorial concentration. Nevertheless, recent clinical evidence shows PTCA superiority for immediate ...
Pueyo Esther - - 2008
In this study, the upward I(US) and downward I(DS) slopes of the QRS complex are proposed as indices for quantifying ischemia-induced electrocardiogram (ECG) changes. Using ECG recordings acquired before and during percutaneous transluminal coronary angioplasty (PTCA), it is found that the QRS slopes are considerably less steep during artery occlusion, ...
Noguchi Haruko - - 2008
In Japan, the use of percutaneous transluminal coronary angioplasty (PTCA) for the treatment of acute myocardial infarction (AMI) is extraordinarily frequent, resulting in large medical expenditure. Using chart-based data and exploiting regional variations, we explore what factors explain the frequent use of PTCA, employing propensity score matching to estimate the ...
Mesbahi Asghar - - 2008
Interventional cardiac procedures produce a large amount of X-ray exposures to the patients in comparison with other conventional X-ray imaging procedures. In the current study, the exposure parameters of 580 patients referred to a cardiac angiography department were recorded. The mean values of total kerma-area product (KAP) were 18.6 Gy ...
Kaya Mehmet G - - 2007
OBJECTIVES: Optimal myocardial reperfusion is of great importance for survival of patients with AMI undergoing PTCA. According to the Thrombolysis In Myocardial Infarction (TIMI) 3 score, restoration of epicardial flow is achieved in the majority of patients. However, the myocardial blush grade (MBG) may offer additional information for survival. Therefore, ...
De Rosa Salvatore - - 2007
OBJECTIVES: Aim of the present study was to compare the immediate and long-term effects of AngioJet rheolytic thrombectomy performed in the setting of a percutaneous coronary angioplasty (PTCA) with those of conventional PTCA in patients with acute myocardial infarction (AMI) and angiographic evidence of high intracoronary thrombus burden. BACKGROUND: Plaque ...
Boztosun Bilal - - 2008
Acute myocardial infarction (AMI) in pregnancy is rare and has a high mortality rate of 37-50%. The most important risk factors are advanced maternal age, hypertension and diabetes mellitus. Although thrombolytic therapy, percutaneous transluminal coronary angioplasty (PTCA) and coronary artery by-pass grafting can be performed, primary PTCA and antiplatelet agents ...
Rahman F - - 2007
In this ongoing prospective study conducted in University Cardiac Center, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, from July 2004 to January 2006. Fifty (50) patients (mean age 56+/-7.2 years) underwent stentangioplasty were evaluated. The study group of 50 patients consisted of 42 (84%) men and 08 (16%) women. The ...
Deiner Carolin - - 2007
BACKGROUND: The short-term results for the prevention of coronary restenosis after intravascular brachytherapy (IVBT) and use of drug-eluting stents (DESs) are excellent. The long-term results either lack or present with late complications (e.g., late thrombosis and late catch-up phenomenon leading to late restenosis even years after the initial procedure). Both ...
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