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Results 151 - 164 of 164
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Guttmann R D - - 1977
A hyperimmune antiserum from WfBN F1 hybrid rats primed to hyperacutely reject LBN F1 cardiac allografts has been studied. A large volume of antiserum will cause allograft rejection in less than 1 day. In the in vitro MLI, concentrations of this antiserum as low as 0.05% are markedly suppressive. This ...
Geacintov N E - - 1977
The fluorescence yield (F) of spinach chloroplasts at 100 degrees K measured at 735 nm (photosystem I fluorescence-F 735) and at 685 nm (photosystem II fluorescence-F 685) has been determined with different modes of laser excitation. The modes of excitation included a single picosecond pulse, sequences of picosecond pulses (4, ...
Poole M - - 1976
Attempts were made to induce a prolonged survival of leg allografts in rats by means of immunological enhancement. AS rats injected with AS anti-August antiserum accepted (AS X August)F1 kidney allografts for longer than 50 days, but rejected F1 leg allografts within 12-16 days. However, AS rats bearing established, enhanced ...
Walsh G M - - 1976
The direct Fick procedure for cardiac output determination in rat was validated by simultaneous comparison with electromagnetic flowmeter techniques. Significant coefficients of correlation were obtained between absolute cardiac output values (r = 0.789, P less than 0.001), increases (r = 0.768, P less than 0.001) and decreases (r = 0.672, ...
Steele G G - - 1975
Full-thickness skin grafts from either BN (Ag-B3) or WF (Ag-B2) rats were transplanted to WF recipients of the same sex. Six to seven days after grafting, recipients were challenged with isografts of a chemically induced rat colon carcinoma, NG-W1. In three of four experiments, mean challenge tumor volumes were greater ...
Mangoushi M A - - 1975
Fifty allografts of 17 day rat fetal ovaries were placed in the bottom of the scrotal wall of 25 normal and 25 castrated adult male rats. Of these, 5 did not take and 11 were destroyed by the allograft reaction. The remaining 34, which were reasonably tolerated, showed, whether the ...
Kakita A - - 1975
The immunosuppressive effects of prostaglandin E1 and procarbazine hydrochloride were compared in a vascularized organ xenograft model. Hamster-to-rat cardiac grafts were used. Both procarbazine hydrochloride and prostaglandin E1 prolonged survival of the xenograft. Prostaglandin E1 had the additional feature of coincident suppression of hemagglutination titer to hamster red cells. Prostaglandin ...
Bitter-Suermann H - - 1975
Grafting of the spleen as an organ of full immunological competence in inbred rats was found to be a useful tool for studies of immunological parameters, which would be difficult to evaluate in outbred and larger animals. Early results indicate that the spleen is under certain circumstances less susceptible to ...
Osuntokun B O - - 1974
Chronic cyanide intoxication of dietary origin and riboflavine deficiency are believed to be major aetiological factors in Nigerian tropical ataxic neuropathy. The results are presented of a double-blind controlled therapeutic trial of combinations of large doses of hydroxocobalamin and cystine as cyanide binding agents together with riboflavine or placebos in ...
Balch C M - - 1973
Lewis kidneys were grafted into BN recipients and examined at daily intervals up to 6 days after grafting with immunofluorescent reagents. A horse antiserum specific for T lymphocytes revealed an increasing number of T lymphocytes in the cellular infiltrates of rejecting allografts. These were detectable 1 day after grafting, reached ...
Beck F J - - 1973
1. A local graft versus host reaction in rats permits the evaluation of drug action on (i) donor (parental) animals and (ii) recipient animals (F(1) hybrid) prior to establishing a lymphoid cell graft to detect drugs which might attenuate immunocompetence over a prolonged period (e.g. steroids).2. Treatment of the recipient ...
Lubaroff D M - - 1973
The role of bone marrow-derived cells in the rejection of skin allografts in rats was investigated. Lewis rats, rendered tolerant of BN antigens and bearing healthy grafts, were thymectomized, irradiated with 900 rad, and injected with varying doses of either normal isologous bone marrow, normal lymph node cells, and/or lymph ...
Roberts J B - - 1970
1. Carbon-14 labelled pyridostigmine in single doses was given by intramuscular injection to pregnant rats, and maternal blood, foetal and placental homogenates were examined for total radioactive content, pyridostigmine and its metabolite, 3-hydroxy-N-methyl pyridinium.2. The level of radioactivity in all tissues was highest at 15 min and fell to negligible ...
Szollosi D - - 1965
Electron microscope observations of osmium tetroxide-fixed rat eggs indicate that small nucleoli are extruded from pronuclei in a sharply demarcated time period after sperm penetration. Approximately 4(1/2) hours after sperm penetration, fine fibrous material aggregated in distinct loci along the inner surface of the nuclear envelope and condensed into small, ...
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