Following either chronic exposure to 6 degrees C, or outdoor winter exposure, or chronic treatment with tyramine rats were exposed to -40 degrees C and their oxygen consumption and colonic temperature monitored. Fall in body temperature with time of exposure followed a sigmoid curve which had an inflection point around ...

The results of biomedical investigations carried out in flights of the Salyut and Skylab orbital stations give evidence that during prolonged weightlessness cosmonauts and astronauts remain in a good physical and mental condition. They fill specialists with optimism in regards to a further increase of the duration of manned space ...

The effects of 5-(4'-chlorobutyl)-picolinic acid (FD-008), a new dopamine beta-hydroxylase inhibitor of fusaric acid derivatives, on the central nervous system in mice and rats were investigated. FD-008 and fusaric acid did not show marked effects on spontaneous movement, convulsion, sleeping time, tremor and conditioned avoidance response but lowered the body ...

Puromycin fails to alter minimal oxygen consumption of rats treated with thyroxine, provided the rectal temperatures of these rats are maintained at 37.8 degrees to 38.1 degrees C. The previously reported puromycin-induced decline in basal metabolic rate of thyroxine-treated rats may have been due to the hypothermia produced by this ...

1. An intravenous injection into rats of 1 mg/kg (-)-Delta(9)-tetrahydrocannabinol Delta(9)-THC) had no effect on rectal temperature and produced in the subcellular fractions of the brain a shift of 5-hydroxytryptamine (5-HT) from the particulate or ;bound' 5-HT to the supernatant or ;free' fraction, whereas the noradrenaline (NA) decreased in both ...

1. Intraperitoneal injection of graded doses of ketamine produced a dose-dependent fall in body temperature of rats. Similarly, intracerebral injection of much smaller doses produced hypothermia.2. Pretreatment of the rats with p-chlorophenylalanine (PCPA) greatly attenuated the hypothermic response to ketamine whereas the intraperitoneal injection of 5-hydroxytryptophan in PCPA-treated rats restored ...

The breathing frequency, tidal volume and partial pressure of CO2 in arterial blood (PaCO2) were measured continuously in urethan anaesthetized rats at different body temperatures. In urethan anaesthesia the colonic temperature of our rats averaged 33.5 plus or minus 1.29 degree Celsius, when the ambient temperature was 22-24 degree Celsius. ...

1. Intraperitoneal administration of graded doses of tetrahydronaphthylamine (THN) to rats caused a dose dependent decrease in body temperature.2. Intracisternal injection of graded doses of THN induced hypothermia, and implantation of crystalline THN rostral to the medial preoptic area and caudal to the striatum, caused hyperthermia.3. Pretreatment of the rats ...

1. Rats which had been pretreated with intraventricular injections of 6-hydroxydopamine (6-OHDA) to cause a selective depletion of brain noradrenaline (NA) to 20.7% of control brain NA and brain dopamine (DA) to 34.6% of control brain DA retained an unimpaired ability to regulate their body temperatures on exposure to heat ...

Decreases of 40 percent in cardiac and respiratory rates occur during the first 12 to 16 hours after 2-week-old rat pups are separated from their mothers. These rates decrease without significant alteration in activity level and despite maintenance of body temperature, of nutrition by intubation, of an intact litter, and ...

Thesis (M. Sc.)--University of Hong Kong, 1968.

1. Intraperitoneal administration of graded doses of tetrahydronaphthylamine (THN) to rats caused a dose dependent decrease in body temperature.

Evidence is presented that infectious catarrh of the rat is caused by Gram-negative coccobacilliform bodies which resemble the agents of fowl coryza and mouse catarrh. These bodies were demonstrable microscopically in at least 90 per cent of the exudates from the nasal passages and middle ears. The characteristic syndrome was ...

We have determined the age dependence of the characteristics of the cytoplasmic phase separation of lenses from normal and galactosemic young rats. In the normal lens, the temperature at which the phase separation occurs decreases monotonically with age. In the lenses of rats fed with a high galactose diet, the ...

A tracking procedure was used to investigate the ability of rats to regulate their ambient temperature. Rats were placed in a chamber with two levers; depressions of one lever controlled a cold-water flow (11 degrees C) and the other controlled the flow of hot water (57 +/- 1 degrees C). ...

1. In unanaesthetized rats, a dose of 50 mug of hemicholinium-3 injected into the cerebral ventricles produced a prolonged hypothermia which was unaffected by the simultaneous administration of choline. This suggests that it was not due to inhibition of acetylcholine synthesis.2. An intraperitoneal injection of 50 mug of hemicholinium-3 also ...

Radar cross section measurements of an Apollo Command Module mock-up were obtained at RAT SCAT. Measurements were taken at frequencies of 2200 and 5690 megahertz with both vertical and horizontal antenna polarizations. In addition, circular polarization and cross polarization measurements were obtained at 5690 megahertz. Target orientations measured were 0 ...

Rats exposed to heat learn to take showers and thus defend themselves against hyperthermia; thereafter the rate of showering is a direct function of ambient temperature. The showering effectively replaces spreading of saliva as the major defense against heat in desalivate rats, and appears to be highly preferred to the ...

A cytoplasmic structure exhibiting a peculiar configuration of agranular reticulum has been found in the rat pinealocyte, and has been designated a canaliculate lamellar body. It consists of a number of fenestrated, flat cisternae which are closely spaced. They bear some distant resemblance to the annulate lamellae previously reported in ...

The development of the mid-body has been studied in mitotic erythroblasts of the rat bone marrow by means of thin sections examined with the electron microscope. A differentiated region on the continuous spindle fibers, consisting of a localized increase in density, is observed at the equatorial plane. The mid-body seems ...

The antithyroid drug, propylthiouracil (PTU), administered to male rats for 4 wk, did not reduce spontaneous running activity in air at 25 C. When room temperature was lowered to 8 C. for 4 days, PTU-treated rats increased their activity level during the first day of exposure but decreased it thereafter. ...

Thyroidectomy (propylthiouracil treatment) and adrenalectomy increased rate of cooling of rats restrained and subjected to air at 5 C. At the same colonic temperature during cooling, both thyroidectomized and adrenalectomized rats maintained higher skin temperatures than did control rats. Heat production (measured by oxygen consumption) was determined for thyroidectomized and ...

Kidney cortex slices incubated in vitro at 0 degrees C. accumulate radiosulfate from the incubation medium. This process differs from the previously described uptake of radiosulfate by renal tissue incubated at 38 degrees C., for instance, in the lesser sensitivity of the uptake at 0 degrees C. to differential effects ...

Experimentally naive albino rats begin to press a lever for short bursts of radiant heat earlier in a 16-hour session at 2 degrees C than rats that have been living at this temperature for about a month. This difference reflects the different rates at which body temperature in the cold ...

Evidence is presented that infectious catarrh of the rat is caused by Gram-negative coccobacilliform bodies which resemble the agents of fowl coryza and mouse catarrh. These bodies were demonstrable microscopically in at least 90 per cent of the exudates from the nasal passages and middle ears. The characteristic syndrome was ...

The work of previous investigators was confirmed in that the microorganism of rat-bite fever was found to have flagella which are clearly visible by dark-field illumination and which can be stained. The best staining is obtained with alkalinized Akashi solution, which is a modification of Giemsa's solution; the vapor of ...