Seaweed extract for joint health.
Article Type: Report
Subject: Osteoarthritis (Care and treatment)
Osteoarthritis (Research)
Marine algae as food (Health aspects)
Marine algae as food (Research)
Marine algae as food (Nutritional aspects)
Author: Finney-Brown, Tessa
Pub Date: 03/22/2010
Publication: Name: Australian Journal of Medical Herbalism Publisher: National Herbalists Association of Australia Audience: Academic Format: Magazine/Journal Subject: Health Copyright: COPYRIGHT 2010 National Herbalists Association of Australia ISSN: 1033-8330
Issue: Date: Spring, 2010 Source Volume: 22 Source Issue: 1
Topic: Event Code: 310 Science & research
Accession Number: 223823996
Full Text: Myers SP et al. 2010. A combined phase I and II open label study on the effects of a seaweed extract nutrient complex on osteoarthritis. Biologics: Targets & Therapy 4;33-44.

This small study tested a Maritech[R] extract formulation containing a blend of extracts from three different species of brown algae, plus nutrients in an open label combined phase I and II pilot scale study to determine both acute safety and efficacy in osteoarthritis of the knee. The formulation contained Maritech[R] seaweed extract Fucus vesiculosis (85% w/w), Macrocystis pyrifera (10% w/w) and Laminaria japonica (5% w/w) plus vitamin B6, zinc and manganese.

Twelve participants (5 female and 7 male with an average age of 62), with osteoarthritis of the knee took either 100 mg or 1000 mg per day for 12 weeks. Researchers used the internationally validated COAT (Comprehensive Osteoarthritis Test) assessment protocol which has 4 sub scales: pain, stiffness, difficulty with physical activity and overall symptom severity measured weekly. Results showed a dose dependent response with the lower dose associated with an 18% reduction in symptoms, while the higher dose was associated with a 52% reduction in symptoms.

In addition to the apparent efficacy to reduce the symptoms of osteoarthritis in a dose dependent manner, the researchers noted that the ingredient was well tolerated. The authors conclude that the efficacy of the preparation now needs to be demonstrated in a phase III randomised controlled trial. The study co author and Marinova's senior scientist Dr Helen Fitton considered that the the particularly exciting finding from this trial was that both groups of patients who took the Maritech[R] seaweed extract felt a significant reduction in pain after just one week of treatment.

Tessa Finney-Brown MNHAA
Gale Copyright: Copyright 2010 Gale, Cengage Learning. All rights reserved.

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