New pre-eclampsia and diet link.
Article Type: Brief article
Subject: Preeclampsia (Diagnosis)
Preeclampsia (Causes of)
Preeclampsia (Complications and side effects)
Milk (Chemical properties)
Milk (Health aspects)
Biological markers (Research)
Author: Thompson, June
Pub Date: 10/01/2009
Publication: Name: Community Practitioner Publisher: Ten Alps Publishing Audience: Academic Format: Magazine/Journal Subject: Health; Health care industry Copyright: COPYRIGHT 2009 Ten Alps Publishing ISSN: 1462-2815
Issue: Date: Oct, 2009 Source Volume: 82 Source Issue: 10
Topic: Event Code: 310 Science & research
Product: Product Code: 2026000 Fluid Milk & Cream; 2026200 Packaged Milk & Cream NAICS Code: 311511 Fluid Milk Manufacturing SIC Code: 2023 Dry, condensed, evaporated products; 2026 Fluid milk
Geographic: Geographic Scope: United Kingdom Geographic Code: 4EUUK United Kingdom
Accession Number: 209163262
Full Text: Ergothioneine, found in unpasteurised dairy products, has been detected in unusually high levels in the red blood cells of pregnant women with pre-eclampsia (PE). Almost 10% of pregnancies after 20 weeks are affected by PE and it is a major cause of maternal and fetal morbidity and mortality. Using H-nuclear magnetic resonance spectroscopy and statistical models, researchers sought to identify 'biomarkers' present in erythrocytes to distinguish between women with normal pregnancy and those with PE. Blood samples were taken from 37 pregnant women, and erythrocytes from those with PE and with no symptoms were compared. Significantly higher concentrations of the ergothioneine were found in erythrocytes from women with PE. The authors suggest that ergothioneine may be an indicator of PE and could help in understanding its cause.

Turner E, Brewster J, Simpson N, Walker J, Fisher J. Imidazole-based erythrocyte markers of oxidative stress in pre-eclampsia: an NMR investigation. Reproductive Sciences, 2009; doi: 10.1177/1933719109340928 (5 August 2009).
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