New WHO guidelines on PMTCT and infant feeding.
Subject: Antiviral agents (Dosage and administration)
Perinatal infection (Prevention)
HIV infection (Prevention)
Breast feeding (Safety and security measures)
Pub Date: 05/01/2010
Publication: Name: Reproductive Health Matters Publisher: Reproductive Health Matters Audience: General Format: Magazine/Journal Subject: Family and marriage; Health; Women's issues/gender studies Copyright: COPYRIGHT 2010 Reproductive Health Matters ISSN: 0968-8080
Issue: Date: May, 2010 Source Volume: 18 Source Issue: 35
Topic: Event Code: 260 General services; 350 Product standards, safety, & recalls
Organization: Organization: World Health Organization
Accession Number: 236247769
Full Text: New guidelines on the use of antiretrovirals for prevention of mother to child transmission (PMTCT) recommend lifelong antiretroviral therapy (ART) for all pregnant women with serious or advanced disease or with a CD4 count at or below 3 50 cells/ml regardless of symptoms. This could prevent 75% of all MTCT and is consistent with the new adult ART recommendations. In women who do not need ART for their own health, ART should start earlier in the pregnancy, at 14 weeks or as soon as possible thereafter, and should continue throughout the breastfeeding period. This change reflects clinical trials showing the efficacy of antiretrovirals in preventing transmission of HIV to the infant while breastfeeding. Where mothers receive ART for their own health, infants should receive prophylaxis with nevirapine for six weeks after birth if the mother is breastfeeding, and prophylaxis with either nevirapine or zidovudine for six weeks if the mother is not breastfeeding. Breastfeeding and prophylaxis should continue for one year if the infant is either HIV-negative or of unknown status. Where mother and infant are both HIV-positive, breastfeeding should be encouraged for at least the first two years of life, in line with recommendations for the general population. (1,2)

(1.) World Health Organization. Rapid advice: use of antiretroviral drugs for treating pregnant women and preventing HIV infection in infants. 30 November 2009.

(2.) World Health Organization. Rapid advice: revised WHO principles and recommendations on infant feeding in the context of HIV. 30 November 2009.
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