Midlife overweight and dementia risk.
Article Type: Brief article
Subject: Dementia (Risk factors)
Middle age (Health aspects)
Obesity (Complications and side effects)
Obesity (Demographic aspects)
Author: Thompson, June
Pub Date: 10/01/2009
Publication: Name: Community Practitioner Publisher: Ten Alps Publishing Audience: Academic Format: Magazine/Journal Subject: Health; Health care industry Copyright: COPYRIGHT 2009 Ten Alps Publishing ISSN: 1462-2815
Issue: Date: Oct, 2009 Source Volume: 82 Source Issue: 10
Geographic: Geographic Scope: United Kingdom Geographic Code: 4EUUK United Kingdom
Accession Number: 209163263
Full Text: Being overweight in midlife increases the risk of dementia later on, according to a study. Long-term effects of overweight on physical health and survival are well known, and people often lose weight before diagnosis and early on in dementia. To examine whether midlife overweight increases dementia risk later in life, researchers followed up 1152 participants of the Swedish Twin Registry whose body mass index was assessed at the age of 45 to 65 years in 1963. They were later screened for dementia in a prospective study with up to 40 years' follow up and 312 were diagnosed. Midlife overweight significantly increased the risk of dementia in old age, even after controlling for known factors related to vascular risk. The risk was increased for both Alzheimer's disease and vascular dementia, and followed the same pattern for men and women. This gives further support to the notion that overweight in midlife increases later risk of dementia, conclude the researchers.

Hassing L, Dahl A, Thorvaldsson V, Berg S, Gatz M, Pedersen N, Johansson B. Overweight in midlife and risk of dementia: a 40-year follow-up study. Int J Obesity, 2009; 33(8): 893-8.
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