Menopause transition data.
|Article Type:||Brief article|
Cardiovascular diseases (Risk factors)
Women (Health aspects)
|Publication:||Name: South African Journal of Obstetrics and Gynaecology Publisher: South African Medical Association Audience: Academic Format: Magazine/Journal Subject: Health Copyright: COPYRIGHT 2010 South African Medical Association ISSN: 0038-2329|
|Issue:||Date: April, 2010 Source Volume: 16 Source Issue: 2|
The Study of Women's Health Across the Nation (SWAN) is an
American initiative that documents women through their menopause
transition. Over 1 000 women are being monitored from about the age of
47 years for the next 10 years of their lives.
Sutton-Tyrell et al. (J Am Coll Cardiol 2009; 54: 2366-2375) report that deleterious lipid changes coincide with the cessation of menstruation. More precisely, in the year before and after her final menstrual period a woman is likely to experience substantial increases in total cholesterol levels. Also raised are low-density lipoproteins and apolipoprotein B, which are associated with raised cardiovascular risk. The changes are independent of age and ethnicity. Quite how these changes can be influenced by exogenous hormones or lifestyle remains to be seen.
|Gale Copyright:||Copyright 2010 Gale, Cengage Learning. All rights reserved.|