Investigation of the effect of ginger on the lipid levels. A double blind controlled clinical trial.
Subject: Medical research
Medicine, Experimental
Clinical trials
Pub Date: 12/01/2008
Publication: Name: Alternative Medicine Review Publisher: Thorne Research Inc. Audience: Academic; Professional Format: Magazine/Journal Subject: Health Copyright: COPYRIGHT 2008 Thorne Research Inc. ISSN: 1089-5159
Issue: Date: Dec, 2008 Source Volume: 13 Source Issue: 4
Topic: Event Code: 331 Product development
Product: Product Code: 8000200 Medical Research; 9105220 Health Research Programs; 8000240 Epilepsy & Muscle Disease R&D NAICS Code: 54171 Research and Development in the Physical, Engineering, and Life Sciences; 92312 Administration of Public Health Programs SIC Code: 8730 Research and Testing Services
Accession Number: 192485120
Full Text: Alizadeh-Navaei R, Roozbeh F, Saravi M, et al. Saudi Med J 2008;29:1280-1284.

OBJECTIVE: To study the effect of fine powder of ginger on lipid level in volunteer patients. METHODS: This is a double blind controlled clinical trial study in 2 cardiac clinics Cardiac Disease Clinic, Babol, north of Iran, between April to May 2004. We randomly divided the patients with hyperlipidemia into 2 groups, treatment group (receiving ginger capsules 3 g/day in 3 divided doses) and placebo group (lactose capsule 3 g/day in 3 divided doses) for 45 days. All subjects with diabetes mellitus, hypothyroidism, nephrotic syndrome, and alcohol drinking, pregnancy and peptic ulcer were excluded. Lipid concentrations profile before and after treatment was measured by enzymatic assay. RESULTS: Forty-five patients in the treatment group and 40 patients in placebo group participated in this study. There was a significant reduce in triglyceride, cholesterol, low density lipoprotein (LDL), very low density lipoprotein (VLDL), levels of before and after study separately in each group (p<0.05). Mean changes in triglyceride and cholesterol levels of ginger group were significantly higher than placebo group (p<0.05). Mean reduction in LDL level and increase in high density lipoprotein level of ginger group were higher than the placebo group, but in VLDL level of placebo was higher than ginger (p > 0.05). CONCLUSION: The results show that ginger has a significant lipid lowering effect compared to placebo.
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