Green tea is effective in treating genetic disorder and types of tumors, study suggests.
Subject: Tumors (Research)
Genetic disorders (Research)
Genetic research
Medical research
Medicine, Experimental
Green tea
Pub Date: 09/22/2011
Publication: Name: Annals of the American Psychotherapy Association Publisher: American Psychotherapy Association Audience: Academic; Professional Format: Magazine/Journal Subject: Psychology and mental health Copyright: COPYRIGHT 2011 American Psychotherapy Association ISSN: 1535-4075
Issue: Date: Fall-Winter, 2011 Source Volume: 14 Source Issue: 3
Topic: Event Code: 310 Science & research Canadian Subject Form: Tumours
Product: Product Code: 8000200 Medical Research; 9105220 Health Research Programs; 8000240 Epilepsy & Muscle Disease R&D NAICS Code: 54171 Research and Development in the Physical, Engineering, and Life Sciences; 92312 Administration of Public Health Programs
Persons: Named Person: Smith, Thomas
Accession Number: 277270188
Full Text: A compound found in green tea shows great promise for the development of drugs to treat two types of tumors and a deadly congenital disease. The discovery is the result of research led by principal investigator, Dr. Thomas Smith at The Donald Danforth Plant Science Center and his colleagues at The Children's Hospital of Philadelphia.

Using atomic structures to understand the differences between animals and plants, Dr. Smith and his colleagues discovered that two compounds found naturally in green tea are able to compensate for this genetic disorder by turning off GDH in isolation and when the green tea compounds were administered orally. The Smith lab also used X-ray crystallography to determine the atomic structure of these green tea compounds bound to the enzyme. With this atomic information, they hope to be able to modify these natural compounds to design and develop better drugs. Their findings were recently published in The Journal of Biological Chemistry.

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Donald Danforth Plant Science Center (2011, Aug 15). Green tea is effective in treating genetic disorder and types of tumors, study suggests. ScienceDaily. Retrieved from http://www.sciencedaily.com/releases/2011/08/1108151136071
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