Avian Pathol.: Squamous cell carcinoma with presence of poxvirus-like inclusions in the foot of a pink-backed pelican (Pelecanus rufescens).
Article Type: Brief article
Subject: Squamous cell carcinoma (Causes of)
Squamous cell carcinoma (Research)
Pelicans (Health aspects)
Pelicans (Research)
DNA viruses (Health aspects)
DNA viruses (Research)
Authors: Pesaro, S.
Biancani, B.
Fabbrizi, G.
Rossi, G.
Pub Date: 09/01/2009
Publication: Name: Journal of Avian Medicine and Surgery Publisher: Association of Avian Veterinarians Audience: Academic Format: Magazine/Journal Subject: Health Copyright: COPYRIGHT 2009 Association of Avian Veterinarians ISSN: 1082-6742
Issue: Date: Sept, 2009 Source Volume: 23 Source Issue: 3
Topic: Event Code: 310 Science & research
Geographic: Geographic Scope: United States Geographic Code: 1USA United States
Accession Number: 252006995
Full Text: Squamous cell carcinoma (SCC) or avian keratoacanthoma is a neoplastic skin lesion of unknown etiology that has been well described in birds. Some studies have reported that poxviruses may contribute to the onset of SCC. Here we describe a case of SCC on the underside of a pelican's foot. Histologically, the tumor consisted of irregular cords of pleomorphic epithelial cells that invaded the adjacent tissues. Additionally, keratinized epithelial cells and moderate numbers of keratin pearls were observed. Intracytoplasmic inclusions, a characteristic of this virus, were observed in some of these cells, and viral particles were characterized by electron microscopy. Although the etiology of the carcinoma in this case may have been secondary to chronic focal trauma, the possibility of a latent or chronic form of fowlpox should be considered in the pathogenesis of the lesion

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