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Adherence to HIV treatment in pregnancy and
post-partum: USA.
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| Article Type: | Brief article |
| Subject: |
Pregnant women
(Care and treatment) HIV infection (Care and treatment) Disease transmission (Prevention) |
| Pub Date: | 11/01/2009 |
| Publication: | Name: Reproductive Health Matters Publisher: Reproductive Health Matters Audience: General Format: Magazine/Journal Subject: Family and marriage; Health; Women's issues/gender studies Copyright: COPYRIGHT 2009 Reproductive Health Matters ISSN: 0968-8080 |
| Issue: | Date: Nov, 2009 Source Volume: 17 Source Issue: 34 |
| Geographic: | Geographic Scope: United States Geographic Code: 1USA United States |
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| Accession Number: | 225074408 |
| Full Text: |
For women with HIV, pregnancy is a time when maintenance of
maternal health and reduction of vertical HIV transmission are primary
concerns. This study examined self-reported antiretroviral adherence in
HIV-positive pregnant and post-partum women participating in the US
Women and Infants Transmission Study, based on interviews during the
third trimester of pregnancy and six months post-partum. During the
third trimester visit, 77% of 399 women completed the adherence report
and 61% of these (188/309) reported complete adherence. Factors
associated with non-adherence were advanced HIV disease status, higher
viral load and more health-related symptoms. At six months postpartum,
55% completed the measure and 44% of these reported complete adherence.
Factors associated with non-adherence were ethnicity, more
health-related symptoms and clinical site. Multivariate analyses across
the two visits revealed that more health-related symptoms, higher viral
load, increased alcohol use and clinical site were independently
associated with non-adherence. Medication adherence was more likely
during pregnancy than post-partum, perhaps due to motivation to reduce
vertical transmission and/or intensive antenatal attention. Women need
more support to adhere to HIV treatment and health care during and after
the post-partum period. (1) (1.) Mellins CA, Chu C, Malee K, et al. Adherence to antiretroviral treatment among pregnant and postpartum HIV-infected women. AIDS Cate 2008 ;20(8) :958-68. |
| Gale Copyright: | Copyright 2009 Gale, Cengage Learning. All rights reserved. |
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