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Results 301 - 350 of 4737
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Mahn F F Division of Neurological Pain Research and Therapy, Department of Neurology, Christian-Albrechts-Universität Kiel, - - 2014
Human experimental pain models play an important role in studying neuropathic pain mechanisms. The objective of the present study was to test the reproducibility of the topical menthol model over a 1-week period. We performed an open, two-period study in 10 healthy volunteers with 40 menthol applications. The side of ...
Schild Michael H MH Department of Radiation Oncology, Mayo Clinic Arizona, Scottsdale, - - 2014
Primary pulmonary Hodgkin lymphoma (PPHL) is a rare entity. Most reported cases occurred before the availability of PET scan for accurate staging of the disease. We report a case of PPHL for which PET/CT scan was used and surgery was performed to confirm the diagnosis. A review of cases of ...
Mohsin-Shaikh Soomal S The Centre for Medication Safety and Service Quality, Imperial College Healthcare NHS Trust, Charing Cross Hospital, Fulham Palace Road, London, W6 8RF, - - 2014
Background Medication errors are common in hospital inpatients. While many interventions have been proposed to address these problems, few have been shown to have significant benefits. A complementary approach is to facilitate greater involvement of patients with their inpatient medication. However, there is relatively little research in this area and ...
Bindon Keren A - - 2014
Cabernet Sauvignon and Shiraz grapes were sourced from different regions within Australia, and microvinified with a skin contact period of 6 days. Grape samples were extracted using two protocols: a 15% v/v ethanol, 10 g/L tartaric acid extract of gently-crushed berries (wine-like, WL) and a 50% v/v ethanol, pH 2 ...
Kilsdonk Iris D ID Department of Radiology, VU University Medical Center, De Boelelaan 1118, 1081 HZ, Amsterdam, The Netherlands, - - 2014
Recently, a new MRI technique was developed at 3 Tesla (T), called fluid attenuated inversion recovery* (FLAIR*). In this study, we implemented FLAIR* in an existing MS cohort at 7 T, to investigate whether we could corroborate results of previous 7 T studies that introduced specific MS lesion characteristics. Furthermore, we aimed to ...
Wu Minfei M Bioengineering Laboratory, Department of Orthopaedic Surgery, Harvard Medical School/Massachusetts General Hospital, Boston, MA, - - 2014
Many studies have reported on the segmental motion range of the lumbar spine using various in vitro and in vivo experimental designs. However, the in vivo weightbearing dynamic motion characteristics of the L4-5 and L5-S1 motion segments are still not clearly described in literature. This study investigated in vivo motion ...
Kaur Jasmit J Department of Botanical and Environmental Sciences, Guru Nanak Dev University, Amritsar, 143005, Punjab, - - 2014
Harike is a wetland of international importance under the Ramsar Convention. The present study entails the investigation of mutagenic, genotoxic and cytotoxic effect of surface water samples collected from five different areas of the Harike wetland by using the histidine reversion point mutation assay in Salmonella typhimurium (TA98 and TA100) ...
Djawe Kpandja K a Division of HIV/AIDS Prevention , Centers for Disease Control and Prevention , Atlanta , GA , - - 2014
In Florida, the HIV case rate among black men is five times that of white men; tailored HIV prevention interventions are lacking. Historical concerns regarding trust with public health venues and sharing sensitive information make face-to-face data collection with some rural, southern black men challenging. We evaluated the feasibility and ...
Stragier E E 1] Faculté de Médecine Pierre et Marie Curie, Center of Psychiatry and Neurosciences, INSERM UMR 894-CPN, Site Pitié-Salpêtrière, Paris, France [2] Université Paris Descartes, Paris, France [3] UPMC, Université Paris 6, UMR S894, Paris, - - 2014
High ethanol intake is well known to induce both anxiolytic and anxiogenic effects, in correlation with chromatin remodeling in the amygdaloid brain region and deficits in cell proliferation and survival in the hippocampus of rodents. Whether only moderate but chronic ethanol intake in C57BL/6J mice could also have an impact ...
Sendi Khalil K Otolaryngology Head and Neck Surgery Department, King Abdulaziz University Hospital, Jeddah, Saudi Arabia, - - 2014
The aim of this study was to evaluate the post-operative complications of using balloon-expandable metallic stents in treatment of benign, major subglottic and tracheal stenosis in adult patients whom conventional therapy has failed and to demonstrate how to deal with these complications in the long run. A retrospective review of ...
Peter Wilfred W Department of Orthopaedics, Leiden University Medical Center (LUMC) , Leiden , the Netherlands - - 2014
Abstract Purpose: To determine the effectiveness of an interactive educational intervention on a physiotherapy guideline for hip and knee osteoarthritis. Method: Physiotherapists were randomly allocated to a 3-h interactive educational course with the collaboration of three patient partners or no intervention. Assessments comprised questionnaires on adherence (score range 0-24), knowledge ...
Pengel Kenneth E KE Department of Radiology, The Netherlands Cancer Institute, PO Box 90203, 1006 BE, Amsterdam, The - - 2014
To explore the potential complementary value of PET/CT and dynamic contrast-enhanced MRI in predicting pathological response to neoadjuvant chemotherapy (NAC) of breast cancer and the dependency on breast cancer subtype. We performed (18)F-FDG PET/CT and MRI examinations before and during NAC. The imaging features evaluated on both examinations included baseline ...
de Hauteclocque A A CIC 802, - - 2014
Several reports have suggested a relationship between male sex and albuminuria in Type 2 diabetes, but impact on renal function decline has not been established. Our aim was to describe the influence of sex on renal function decline in Type 2 diabetes. SURDIAGENE, an inception cohort, consisted in 1470 people with Type 2 ...
Nwawka O Kenechi OK Department of Radiology and Imaging, Hospital for Special Surgery, 535 East 70th Street, 3rd Floor, New York, NY, 10021, USA, - - 2014
Membranous lipodystrophy, also known as Nasu-Hakola disease, is a rare hereditary condition with manifestations in the nervous and skeletal systems. The radiographic appearance of skeletal lesions has been well described in the literature. However, CT and MRI findings of lesions in the bone have not been documented to date. This ...
Wilson Stephen J SJ Department of Psychology, Pennsylvania State University, University Park, PA, USA, - - 2014
As a group, cigarette smokers exhibit blunted subjective, behavioral, and neurobiological responses to nondrug incentives and rewards, relative to nonsmokers. Findings from recent studies suggest, however, that there are large individual differences in the devaluation of nondrug rewards among smokers. Moreover, this variability appears to have significant clinical implications, since ...
Zhang Liwen L Key Laboratory for Zoonosis Research, Ministry of Education, The First Hospital, Jilin University, 130032, Changchun, - - 2014
The aim of this study was to assess the long term impact of ETV on T, B and NK cell immunity in patients with suboptimal responses to adefovir (SRA) chronic hepatitis B (CHB). Thirty SAR CHB patients and 20 age-/gender-matched healthy controls (HC) completed at least six months of ETV ...
Wang Jun J Institute of Animal Nutrition, Sichuan Agricultural University, Ya'an, - - 2014
We examined the effects of sodium butyrate and flavors on feed intake of lactating sows and growth performance of piglets. A total of 52 primiparous sows (Large White) were randomly divided into four treatments (n = 13) and received 6 g/kg sodium butyrate (SB), fruit-milk (FM) flavor and fruit-milk-anise (FMA) flavor with pair ...
Kamarudin Nor Hafizah Ahmad NH Enzyme and Microbial Technology Research Centre, Universiti Putra Malaysia, 43400, Serdang, Selangor, - - 2014
The gene encoding a cold-adapted, organic solvent stable lipase from a local soil-isolate, mesophilic Staphylococcus epidermidis AT2 was expressed in a prokaryotic system. A two-step purification of AT2 lipase was achieved using butyl sepharose and DEAE sepharose column chromatography. The final recovery and purification fold were 47.09 % and 3.45, respectively. ...
Iguchi Hiroaki H Department of Chemistry, Graduate School of Science, Tohoku University, 6-3 Aramaki-Aza-Aoba, Aoba-ku, Sendai, 980-8578, Japan. h-iguchi@m.tohoku.ac.jp - - 2014
(129)I Mössbauer spectroscopy was applied to water-vapor-responsive MMX-type quasi-one-dimensional iodide-bridged Pt complexes (MMX chains) in order to investigate their electronic state quantitatively. Two sets of octuplets observed in K2(H3NC3H6NH3)[Pt2(pop)4I]·4H2O () and one octuplet observed in K2(cis-H3NCH2CH[double bond, length as m-dash]CHCH2NH3)[Pt2(pop)4I]·4H2O () and dehydrated complexes ( and ) indicate a unique ...
Kul Seref S Department of Cardiology, Faculty of Medicine, Bezmialem Vakif University, Adnan Menderes Bulvarı (Vatan cad.), Fatih, 34093, Istanbul, Turkey, - - 2014
Cardiac involvement in sarcoidosis has been associated with poor prognosis. We evaluated myocardial contractility quantitatively in a cohort of pulmonary sarcoidosis (PS) patients with and without cardiac involvement. We also studied markers of fibrosis (tenascin-C [Tn-C] and galectin-3 [Gl-3]) as diagnostic tools for PS and cardiac sarcoidosis (CS). Forty ambulatory ...
Pedro S Gómez-de SG Sensors & Biosensors Group, Departament of Chemistry, Auntonomus University, Edifici Cn., 08193 Bellatera, Catalonia, - - 2014
The present paper describes the use of a microfluidic system to synthesize carbon dots (Cdots) and their use as optical pH sensors. The synthesis is based on the thermal decomposition of ascorbic acid in dimethyl sulfoxide. The proposed microsystem is composed of a fluidic and a thermal platform, which enable ...
Verschuren Jesse Elisabeth JE Department of Rehabilitation Medicine, Center for Rehabilitation, University of Groningen, University Medical Center Groningen , Groningen , the Netherlands - - 2014
Abstract Purpose: Following a lower limb amputation, people may experience limitations in performing sexual activities. However, only little research efforts have been devoted to unravel how people experience their sexuality after such an amputation. Therefore, the purpose of the current study is to describe how people with a lower limb ...
Jin Junjiang J Lab of Low-Dimensional Materials Chemistry, School of Materials Science and Engineering, East China University of Science and Technology, No. 130 Mei-long Road, Shanghai 200237, P.R. China. - - 2014
Mesoporous Beta zeolite has been successfully prepared through hydrothermal synthesis in the presence of cationic ammonium-modified chitosan as the meso-template. Through a subsequent solid-gas reaction between highly dealuminated mesoporous Beta zeolite and SnCl4 steam at an elevated temperature, mesoporous Sn-Beta has been facilely obtained. It was revealed that the addition ...
Dangi Tanushree T Department of Microbiology, King George's Medical University, Lucknow, - - 2014
The pandemic H1N1 strain of Influenza A virus [A(H1N1)pdm09] is now well adapted in human populations. However, it is still causing sporadic outbreaks worldwide with different severity. The present study was planned to understand the genetic diversity (based on the HA1 gene) of influenza A(H1N1)pdm09 strains circulating during the post ...
Scola Gustavo G Department of Psychiatry, University of Toronto, Medical Science Building, Room 4204, 1 king's College Circle, Toronto, ON, M5S 1A8, - - 2014
Mitochondrial complex I dysfunction and alterations in DNA methylation levels are consistently reported in bipolar disorder (BD) and are regulated by lithium. One of the mechanisms by which lithium may exert its effects in BD is by improving mitochondrial complex I function. Therefore, we examined whether complex I dysfunction induces ...
Hosen Mohammad J - - 2014
Pseudoxanthoma elasticum (PXE) is characterized by skin (papular lesions), ocular (subretinal neovascularisation) and cardiovascular manifestations (peripheral artery disease), due to mineralization and fragmentation of elastic fibres in the extracellular matrix (ECM). Caused by mutations in the ABCC6 gene, the mechanisms underlying this disease remain unknown. The knowledge on the molecular ...
Kim Jee Hyun JH The Florey Institute of Neuroscience and Mental Health, Behavioural Neuroscience Division , Parkville, VIC 3052 , - - 2014
Introduction: There are no FDA-approved pharmacotherapies for treating cocaine addiction; thus, developing drugs to treat cocaine dependence is an unmet critical need. Fortunately, there are a number of drugs that are currently in Phase II clinical trial/s. This is due in part to the advances from in vivo imaging in ...
Liu Yang Y Department of Mathematics, University of Pennsylvania, Philadelphia, PA, USA, - - 2014
A commonly used method for evaluating a hospital's performance on an outcome is to compare the hospital's observed outcome rate to the hospital's expected outcome rate given its patient (case) mix and service. The process of calculating the hospital's expected outcome rate given its patient mix and service is called ...
Shao Yebo Y Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, - - 2014
SLIT, a secretory glycoprotein, and its receptor roundabout (ROBO) are expressed in several types of cancer and have been implicated in tumor angiogenesis. The purpose of this study was to determine the prognostic implications of SLIT and ROBO1 expression and their association with clinicopathologic characteristics in gallbladder cancer. A retrospective ...
Zhang Nan N State Key Laboratory of Photocatalysis on Energy and Environment, College of Chemistry, Fuzhou University, Fuzhou 350002, P.R. China. - - 2014
Low cost and easily made bismuth tungstate (Bi2WO6) could be one of the key technologies to make chemicals and fuels from biomass, atmospheric carbon dioxide and water at low cost using solar radiation as an energy source. Its narrow band gap (2.8 eV) enables ideal visible light (λ > 400 ...
Gu Min M College of Light Industry and Food Science, South China University of Technology, Guangzhou, 510641, - - 2014
Frog (Hylarana guentheri) proteins were hydrolyzed by papain and Flavourzyme to obtain antioxidative peptides. The antioxidant activities of the frog protein hydrolysates (FPHs) were measured, including 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity (IC50 = 9.94 ± 0.13 mg/mL), reducing power (0.39 ± 0.01 at 5.0 mg/mL), and oxygen radical absorbance capacity (ORAC) value (789.15 ± 75.10 μmol Trolox equivalents/g). The hydrolysates were purified by ...
Shirazi M M Tehran University of Medical Science, Tehran, - - 2014
The objective structured examination is one of the most valid, reliable, and effective tools for assessing clinical and communication skills, often by use of standard patients (SPs). SPs can also be assessors of those skills. One of the crucial areas when utilizing SP-based assessment is the quality and consistency assurance ...
Wang Chuan - - 2014
The first catalytic, highly C3-selective, stereosepecific ring-opening reaction of 2,3-epoxy alcohols and 2,3-epoxy sulfonamides has been accomplished. This process was efficiently promoted by W-salts and the developed method was applicable to various epoxides with diverse N- and O- nucleophiles affording the products in good to excellent yields (up to 95 ...
Pan Fan F Immunology and Hematopoiesis Division, Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA, - - 2014
Posttranslational modification by ubiquitin tagging is crucial for regulating the stability, activity and cellular localization of many target proteins involved in processes including DNA repair, cell cycle progression, protein quality control, and signal transduction. It has long been appreciated that ubiquitin-mediated events are important for certain signaling pathways leading to ...
Trevor J L JL Division of Pulmonary Allergy and Critical Care Medicine, Department of Medicine, The University of Alabama at Birmingham, Birmingham, AL, - - 2014
Asthma is a common medical condition affecting 300 million people worldwide. Airway inflammation, smooth muscle bronchoconstriction leading to airflow obstruction, and mucous hypersecretion are clinical hallmarks of asthma. The NHLBI Expert Panel Report 3 recommends inhaled corticosteroids (ICS) for patients with moderate to severe persistent asthma. Inhaled corticosteroids (ICS) target ...
New P W PW 0000000256693286 1] Spinal Rehabilitation Unit, Caulfield Hospital, Alfred Health, Melbourne, Victoria, Australia [2] Epworth-Monash Rehabilitation Medicine Unit, Monash University, Melbourne, Victoria, - - 2014
Study design:Prospective open cohort case series.Objectives:To identify opportunities for improvement by recording duration of key processes from acute hospital admission until spinal rehabilitation unit (SRU) admission.Setting:SRU, Victoria, Australia.Methods:Consecutive referrals of patients with recent spinal cord damage had prospective documentation of the key clinical and demographic characteristics and duration (days) of ...
Vincent H K HK Department of Orthopaedics and Rehabilitation, Interdisciplinary Center for Musculoskeletal Training and Research, Divisions of Research, Physical Medicine & Rehabilitation, and Sports Medicine, Gainesville, FL, USA - - - 2014
The purposes of this study were to compare the oxygen cost, metabolic parameters and temporalspatial variables between barefoot and shod running in trained mid-forefoot runners. Experienced runners (N=21; 30.0±10.9 years; 16 men) performed two separate 20 minute treadmill running bouts at ~77% of estimated maximal heart rate. Rate of oxygen ...
Markar Sheraz R SR Department of Thoracic Surgery, Virginia Mason Medical Center, 1100 Ninth Ave, Seattle, WA, 98111, - - 2014
The aim of this study is to determine the effect of the implementation and evolution of a multidisciplinary esophagectomy care pathway on postoperative outcomes over a 20-year experience. All patients undergoing esophagectomy for cancer between 1991 and 2012 were included. Patients were divided into four groups (Gp1 1991-1996, Gp2 1997-2002, ...
Gao Hong H Laboratory of Pediatric Congenital Malformation, Ministry of Public Health, Shengjing Hospital of China Medical University, Shenyang, - - 2014
Hirschsprung's disease (HSCR) is a developmental disorder of the enteric nervous system characterized by aganglionosis in distal gut. In this study, we used two-dimensional gel electrophoresis (2-DE) technology coupled with matrix assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) analysis to identify differentially expressed proteins in the aganglionic (stenotic) and ganglionic ...
Sviland Randi R Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway, - - 2014
This study elaborates on narrative resources emerging in the treatment of longlasting musculoskeletal and psychosomatic disorders in Norwegian psychomotor physiotherapy (NPMP). Patients' experiences produced in focus group interviews were analyzed from a narrative perspective, combining common themes across groups with in depth analysis of selected particular stories. NPMP theory expanded ...
Han Zhijian - - 2014
We aimed to evaluate the feasibility and clinical significance of using a modified liver-mobilization technique to treat renal cell carcinoma (RCC) combined with intrahepatic inferior vena cava (IVC) thrombosis. A total of 11 level III thrombus patients underwent radical nephrectomy with resection of the tumor thrombus from intrahepatic IVC. A ...
Zavattoni Maurizio M Molecular Virology Unit, Microbiology and Virology Department, Fondazione IRCCS Policlinico San Matteo, Pavia, - - 2014
To investigate retrospectively the prognostic significance of maternal, fetal, and neonatal parameters and clinical outcome in 150 HCMV congenital infections during the period 1995-2009. HCMV fetal infection was investigated in amniotic fluid and fetal blood samples. HCMV congenital infection was confirmed in newborn urine and blood samples. Symptomatic infection was ...
Ribeiro J V JV REQUIMTE, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade do Porto, Rua do Campo Alegre s/n, 4169-007, Porto, - - 2014
In this article we propose a method for locating functionally relevant chemical motifs in protein structures. The chemical motifs can be a small group of residues or structure protein fragments with highly conserved properties that have important biological functions. However, the detection of chemical motifs is rather difficult because they ...
Zhang Shuai S Department of Physics, Nanyang Normal University, Nanyang, 473061, - - 2014
The equilibrium geometries, growth patterns, stabilities, and electronic properties of bimetallic Be2Si n (n = 1-11) clusters are systematically investigated at the B3LYP/6-311G(d) level of theory. Harmonic vibrational analysis has been performed to assure that the optimized geometries are stable. The optimized results suggest that the three-dimensional structures are observed for the ...
Ginsberg Jill P JP Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, - - 2014
Infertility is an unfortunate treatment-related consequence for some pediatric malignancies as well as some non-malignant conditions treated with stem cell transplant. Unlike pubertal males, prepubertal males cannot produce semen for cryopreservation. This manuscript reports on the acceptability and safety of a multi-institutional protocol for offering testicular tissue cryopreservation to families ...
Zhang Jian J Department of Chemistry and State Key Laboratory of Synthetic Chemistry, The Chinese University of Hong Kong , Shatin, New Territories, Hong Kong, People's Republic of - - 2014
Conspectus Carboranes are a class of polyhedral boron hydride clusters in which one or more of the BH vertices are replaced by CH units. Their chemistry has been dominated by 12-vertex carboranes for over half a century. In contrast, knowledge regarding supercarboranes (carboranes with more than 12 vertices) had been ...
Beseoglu Kerim K Department of Neurosurgery, Medical Faculty, Heinrich-Heine-Universität Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany, - - 2014
Existing data on perfusion imaging assumes the perihemorrhagic zone (PHZ) in patients with intracerebral hemorrhage (ICH) to be size steady. This study investigates the size of the perihemorrhagic zone (PHZ) in patients with lobar ICH in relation to hematoma volume during the course of treatment using perfusion CT (PCT). The ...
Borschmann Rohan R Institute of Psychiatry, King's College London, London, - - 2014
The prevalence and correlates of self-harm and suicidal behavior in 515 young offenders (mean age 17.3 years, SD = 1.7) serving community-based orders (CBOs; n = 242) or custodial sentences (n = 273) in Victoria, Australia, are described. Results from structured interviews showed that 83 (16.1%) participants reported self-harming in the previous 6 months, and this was more ...
Hegar Badriul B Department of Child Health, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo Hospital, Jakarta, - - 2014
To investigate the efficacy of probiotics added to oral rehydration solution and zinc in the treatment of acute infectious diarrhea in Indonesian children. A prospective randomized double blind placebo-controlled trial was performed to test the efficacy of a probiotic food supplement in 112 children in the Kenari subdistrict, central Jakarta, ...
Turbitt E E Genetics Education and Health Research, Murdoch Childrens Research Institute, Melbourne, VIC, Australia; Department of Paediatrics, The University of Melbourne, Melbourne, VIC, - - 2014
Chromosomal microarray (CMA) testing is now performed frequently in paediatric care. Although CMAs improve diagnostic yields, they increase detection of variants of unknown and uncertain clinical significance (VUS). Understanding parents', paediatricians' and genetic health professionals' (GHPs) views regarding variant disclosure may reduce the potential for communication of unwanted information. A ...
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