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Results 401 - 450 of 1970
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Mun Byeong-Mu BM Department of Rehabilitation Science, Graduate School, Daegu University, Republic of - - 2014
[Purpose] This study sought to identify the gait aspects according to the FES stimulation position in stroke patients during gait training. [Subjects and Methods] To perform gait analysis, ten stroke patients were grouped based on 4 types of gait conditions: gait without FES stimulation (non-FES), gait with FES stimulation on ...
Mainenti Míriam Raquel Meira MR Augusto Motta University Center (UNISUAM): Praça das Nações, 34, 3rd floor, Bonsucesso, Rio de Janeiro, - - 2014
[Purpose] Complaint of pain is common in computer workers, encouraging the investigation of pain-related workplace factors. This study investigated the relationship among work-related characteristics, psychosocial factors, and pain among computer workers from a university center. [Subjects and Methods] Fifteen subjects (median age, 32.0 years; interquartile range, 26.8-34.5 years) were subjected to measurement ...
Nakano Márcia Mariko MM Department of Physical Therapy, Communication Science and Disorders, Occupational Therapy, Faculty of Medicine, University of São Paulo, - - 2014
[Purpose] The aim of this study was to verify the decline in functionality of elderly people. [Subjects and Methods] The study subjects comprised 152 individuals (96 women; 56 men) divided into 3 groups: G1 (60 to 69 years, n=53); G2 (70 to 79 years, n=65); and G3 (80 years or older, n=34). Physical ...
Cheng Chih-Hsiu CH Department of Physical Therapy and Graduate Institute of Rehabilitation Science, College of Medicine, Chang Gung University, Taiwan ; Healthy Aging Research Center, Chang Gung University, - - 2014
[Purpose] Muscle co-contraction is important in stabilizing the spine. The aim of this study was to compare cervical muscle co-contraction in adults with and without chronic neck pain during voluntary movements. [Subjects and Methods] Surface electromyography of three paired cervical muscles was measured in fifteen young healthy subjects and fifteen ...
Melam Ganeswara Rao GR Department of Rehabilitation Sciences, College of Applied Medical Sciences, King Saud University, Saudi - - 2014
[Purpose] The purpose of our study was to investigate the effect of different positions on pulmonary function test (PFT) values such as forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) of asthmatic patients .[Subjects and Methods] Thirty subjects with severe asthma aged between 20-39 years were ...
Yang Jeongok J Division of Physical Education, College of Medical and Life Science, Silla University, Republic of - - 2014
[Purpose] The purpose of this study was to determine the effects of adjusting the scapula into its ideal position through active scapular protraction on the muscle activation and function of the upper extremity. [Subjects] Twenty female college students aged 19-21 without any physical or functional disability were the subjects of ...
Kim Chul C Department of Rehabilitation Medicine, College of Medicine, Sanggye-Paik Hospital, Inje University, Republic of - - 2014
[Purpose] This study investigated the effects of mid, and high exercise intensities on hemodynamic responses and cardiac events during two exercise types of treadmill exercise (TM) and cycle ergometer exercises (CE) in patients with acute coronary syndrome (ACS). [Subjects] Patients who had percutaneous coronary intervention (PCI) for ACS and were ...
Cho Gyeong Hee GH Department of Physical Therapy, College of Rehabilitation Science, Daegu University, Republic of - - 2014
[Purpose] The objective of this study was to determine the effects of virtual reality-based balance training on balance of the elderly. [Methods] The subjects were 32 healthy elderly people aged between 65 and 80, who were divided into a VR (virtual reality) training group (n=17) and a control group (n=15). ...
Park Tae-Jin TJ Department of Design Institute, Inje University: 607 Inje-ro, Gimhae-si, Gyeongsangnam-do 621-749, Republic of - - 2014
[Purpose] The aim of the present study was to examine the influence of wobble board training on static balance, with and without vision, of adolescents with Down syndrome (DS). [Subjects] Ten adolescents with DS were recruited for this study. [Methods] Participants performed quiet standing with their eyes open and closed, ...
Mun Byeong-Mu BM Department of Rehabilitation Science, Graduate School, Daegu University, Republic of - - 2014
[Purpose] This study sought to determine the usefulness of sit to stand training in self-directed treatment of stroke patients. It examined the effect that sit to stand training has on balance and functional movement depending on the form of support surfaces. [Subjects and Methods] Thirty stroke patients were randomly sampled ...
Na Sang Su SS Department of Rehabilitation Science, Graduate School, Daegu University, Republic of - - 2014
[Purpose] To investigate the correlation between the effect treadmill exercise and change in serum proteins in rats with osteoarthritis, a study of proteins was carried out using a mass spectrometer. [Subjects and Methods] Rats were randomly divided into five groups. After 4 weeks of treadmill training, serum from each rat ...
Lee Sang-Heon SH Department of Occupational Therapy, College of Medical Science, Soonchunhyang University, Republic of - - 2014
[Purpose] The objective of this study was to determine users' satisfaction with assistive devices, and their serviceability and effectiveness. [Methods] A random sample of 138 users participated in this study. The Korean-Quebec User Evaluation of Satisfaction with Assistive Technology 2.0 and an additional questionnaire were used for data collection. Data ...
Kim Jung-Hyun JH Department of Physical Therapy, The Graduate School, Sahmyook University, Republic of - - 2014
[Purpose] The aim of this study was to investigate the influence of an unstable surface on trunk and lower extremity muscle activities during various types of bridging exercises. [Subjects] Thirty healthy female adults voluntarily participated in this study. [Methods] All subjects were asked to perform 3 different bridging exercises (bridging ...
Shim Jung-Myo JM Department of Skin and Health Care, Suseong College, Republic of - - 2014
[Purpose] The purpose of this preliminary study was to investigate the effect of manual lymph drainage (MLD) of the neck on frontal electroencephalogram (EEG) asymmetry in subjects with psychological stress. [Subjects] Thirteen subjects with psychological stress participated in the study. [Methods] Subjects received MLD of the neck for 15 min. [Results] ...
Park Jun Hyuk JH Department of Physical Therapy, Graduate School, Silla University, Republic of - - 2014
[Purpose] The purpose of this study was to identify the effects of visual field condition on electromyography of the lower extremities during arm reaching in healthy adults, and to compare differences in electromyography of the lower extremities between young and old adults according to visual fields condition. [Subjects and Methods] ...
Guirro Rinaldo Roberto de Jesus RR Laboratory of Physiotherapeutic Resources, Department of Biomechanics, Medicine and Rehabilitation of the Locomotor System, Laboratory of Physiotherapeutic Resources, Ribeirão Preto Medical School of University of the São Paulo, Brazil ; Post-Graduation Program in Rehabilitation and Functional Performance, Ribeirão Preto Medical School of the University of São Paulo, - - 2014
Although shortwave diathermy has been widely used by physiotherapists, there are a few studies assessing the performance of the equipment in use. The aim of the present study was to evaluate the procedures adopted by physiotherapists as users of shortwave diathermy continuous (CSWD), as well as to measure the power ...
Lim Kyoung Il KI Department of Physical Therapy, Kyungbuk-College, Republic of - - 2014
[Purpose] This research was designed to find out how the so-called "dynamic balance" is affected by doing different types of warm up exercises. In particular, the research is focused on the difference in the effect on dynamic Balance of warming up in water versus on the ground. [Subjects and Methods] ...
Kim Seongho S Department of Physical Therapy, Shingu College, Republic of - - 2014
[Purpose] The aim of this study was to evaluate the efficacy of using spinal stabilizing exercise to reduce atrophy of the multifidus and psoas major muscles, reduce the levels of pain and disability, and increase paraspinal muscle strength in patients with degenerative disc disease (DDD). [Subjects and Methods] In 33 ...
Lee Jeonhyeong J Department of Physical Therapy, Daegu Health College, Republic of - - 2014
[Purpose] The purpose of this study was to compare cervical repositioning errors according to smartphone addiction grades of adults in their 20s. [Subjects and Methods] A survey of smartphone addiction was conducted of 200 adults. Based on the survey results, 30 subjects were chosen to participate in this study, and ...
Kim Jin-Hee JH Department of Physical Therapy, College of Health Sciences, Catholic University of Pusan, Republic of - - 2014
[Purpose] The purpose of this study is to verify whether precise contraction of the pelvic floor muscle (PFM) using visual feedback actually affects the thickness of abdominal muscles. [Subjects] The subjects were 29 healthy adults in their 20s who consented to participate in this study. [Methods] This study provided visual ...
Heo Hyo-Jin HJ Department of Rehabilitation Science, Graduate School, Inje University, Republic of - - 2014
[Purpose] The purpose of this study was to identify the effects of an inclined ankle on the activation of the abductor hallucis muscle during short foot exercises. [Subjects] We recruited 14 healthy volunteers who were free of pain, and did not suffer from arthritis or osteomuscular problems related to the ...
Murakami Kenichi K Tohoku Bunka Gakuen University, - - 2014
[Purpose] The aim of this study was to clarify the relationship between the muscle fiber conduction velocity (MFCV) obtained during muscle twitches from evoked potentials and the dynamic characteristics of muscular tension (muscle dynamic characteristics) by manipulating deep temperature. [Subjects] Subjects were 10 healthy adult men. Their mean age was ...
Pagliai Fernando A FA Microbiology and Cell Science Department, Genetics Institute, Institute of Food and Agricultural Science, University of Florida, Gainesville, Florida, United States of - - 2014
The causal agent of Huanglongbing disease, 'Candidatus Liberibacter asiaticus', is a non-culturable, gram negative, phloem-limited α-proteobacterium. Current methods to control the spread of this disease are still limited to the removal and destruction of infected trees. In this study, we identified and characterized a regulon from 'Ca. L. asiaticus' involved ...
Sundqvist Emilie E Neuroimmunology Unit, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, - - 2014
JC polyomavirus (JCV) carriers with a compromised immune system, such as in HIV, or subjects on immune-modulating therapies, such as anti VLA-4 therapy may develop progressive multifocal leukoencephalopathy (PML) which is a lytic infection of oligodendrocytes in the brain. Serum antibodies to JCV mark infection occur only in 50-60% of ...
Frappier Vincent V Department of Biochemistry, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, - - 2014
Normal mode analysis (NMA) methods are widely used to study dynamic aspects of protein structures. Two critical components of NMA methods are coarse-graining in the level of simplification used to represent protein structures and the choice of potential energy functional form. There is a trade-off between speed and accuracy in ...
Walenda Thomas T Helmholtz Institute for Biomedical Engineering, RWTH Aachen University Medical School, Aachen, - - 2014
Myelodysplastic syndromes (MDS) are triggered by an aberrant hematopoietic stem cell (HSC). It is, however, unclear how this clone interferes with physiologic blood formation. In this study, we followed the hypothesis that the MDS clone impinges on feedback signals for self-renewal and differentiation and thereby suppresses normal hematopoiesis. Based on ...
Feist Adam M AM Department of Bioengineering, University of California San Diego, La Jolla, California, United States of - - 2014
Geobacter species are of great interest for environmental and biotechnology applications as they can carry out direct electron transfer to insoluble metals or other microorganisms and have the ability to assimilate inorganic carbon. Here, we report on the capability and key enabling metabolic machinery of Geobacter metallireducens GS-15 to carry ...
Machado Daniel D The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Horsholm, - - 2014
Constraint-based models of metabolism are a widely used framework for predicting flux distributions in genome-scale biochemical networks. The number of published methods for integration of transcriptomic data into constraint-based models has been rapidly increasing. So far the predictive capability of these methods has not been critically evaluated and compared. This ...
Bai Hao H Department of Computer Science, University of Sheffield, Sheffield, United - - 2014
In the presence of oxygen (O2) the model bacterium Escherichia coli is able to conserve energy by aerobic respiration. Two major terminal oxidases are involved in this process - Cyo has a relatively low affinity for O2 but is able to pump protons and hence is energetically efficient; Cyd has ...
Possik Elite E Goodman Cancer Research Center, McGill University, Montréal, Québec, Canada; Department of Biochemistry, McGill University, Montréal, Québec, - - 2014
Dysregulation of AMPK signaling has been implicated in many human diseases, which emphasizes the importance of characterizing AMPK regulators. The tumor suppressor FLCN, responsible for the Birt-Hogg Dubé renal neoplasia syndrome (BHD), is an AMPK-binding partner but the genetic and functional links between FLCN and AMPK have not been established. ...
Zinovyeva Anna Y AY Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of - - 2014
microRNAs function in diverse developmental and physiological processes by regulating target gene expression at the post-transcriptional level. ALG-1 is one of two Caenorhabditis elegans Argonautes (ALG-1 and ALG-2) that together are essential for microRNA biogenesis and function. Here, we report the identification of novel antimorphic (anti) alleles of ALG-1 as ...
Banerjee Chaitali C Immunobiology Laboratory, Department of Zoology, University of Delhi, Delhi, - - 2014
The role of calcium (Ca2+) and its dependent protease calpain in Aeromonas hydrophila-induced head kidney macrophage (HKM) apoptosis has been reported. Here, we report the pro-apoptotic involvement of calmodulin (CaM) and calmodulin kinase II gamma (CaMKIIg) in the process. We observed significant increase in CaM levels in A. hydrophila-infected HKM ...
Gangel Heike H Department of Physics, University of Cologne, Cologne, - - 2014
Competence for transformation is widespread among bacterial species. In the case of Gram-negative systems, a key step to transformation is the import of DNA across the outer membrane. Although multiple factors are known to affect DNA transport, little is known about the dynamics of DNA import. Here, we characterized the ...
Tang Grace W GW Department of Bioengineering, Stanford University, Stanford, California, United States of - - 2014
Target-based drug discovery must assess many drug-like compounds for potential activity. Focusing on low-molecular-weight compounds (fragments) can dramatically reduce the chemical search space. However, approaches for determining protein-fragment interactions have limitations. Experimental assays are time-consuming, expensive, and not always applicable. At the same time, computational approaches using physics-based methods have ...
Fatumo Segun A SA H3Africa Bioinformatics Network (H3ABioNet) Node, National Biotechnology Development Agency (NABDA), Federal Ministry of Science and Technology (FMST), Abuja, Nigeria; Human Genetics Department, Wellcome Trust Sanger Institute, Cambridge, United Kingdom; International Health Research Group, Department of Public Health & Primary Care, University of Cambridge, Cambridge, United - - 2014
Over the past few decades, major advances in the field of molecular biology, coupled with advances in genomic technologies, have led to an explosive growth in the biological data generated by the scientific community. The critical need to process and analyze such a deluge of data and turn it into ...
Gollo Leonardo L LL Systems Neuroscience Group, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, - - 2014
Zero-lag synchronization between distant cortical areas has been observed in a diversity of experimental data sets and between many different regions of the brain. Several computational mechanisms have been proposed to account for such isochronous synchronization in the presence of long conduction delays: Of these, the phenomenon of "dynamical relaying" ...
Peng Yanyan Y State Key Lab of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China; Department of Biochemistry and Molecular Biology, School of Life Sciences, Peking University, Beijing, - - 2014
RIG-I like receptors (RLRs) recognize cytosolic viral RNA and initiate innate immunity; they increase the production of type I interferon (IFN) and the transcription of a series of antiviral genes to protect the host organism. Accurate regulation of the RLR pathway is important for avoiding tissue injury induced by excessive ...
Limoli Dominique H DH Department of Microbial Infection and Immunity, The Ohio State University, Columbus, Ohio, United States of - - 2014
Acquisition of adaptive mutations is essential for microbial persistence during chronic infections. This is particularly evident during chronic Pseudomonas aeruginosa lung infections in cystic fibrosis (CF) patients. Thus far, mutagenesis has been attributed to the generation of reactive species by polymorphonucleocytes (PMN) and antibiotic treatment. However, our current studies of ...
Metsu Sofie S Department of Medical Genetics, University of Antwerp, Antwerp, - - 2014
Folate-sensitive fragile sites (FSFS) are a rare cytogenetically visible subset of dynamic mutations. Of the eight molecularly characterized FSFS, four are associated with intellectual disability (ID). Cytogenetic expression results from CGG tri-nucleotide-repeat expansion mutation associated with local CpG hypermethylation and transcriptional silencing. The best studied is the FRAXA site in ...
Neri Franco M FM Department of Plant Sciences, University of Cambridge, Cambridge, United - - 2014
Outbreaks of infectious diseases require a rapid response from policy makers. The choice of an adequate level of response relies upon available knowledge of the spatial and temporal parameters governing pathogen spread, affecting, amongst others, the predicted severity of the epidemic. Yet, when a new pathogen is introduced into an ...
Ebert Stefan S Institute for Virology and Research Center for Immunology (FZI), University Medical Center of the Johannes Gutenberg University, Mainz, - - 2014
The lungs are a noted predilection site of acute, latent, and reactivated cytomegalovirus (CMV) infections. Interstitial pneumonia is the most dreaded manifestation of CMV disease in the immunocompromised host, whereas in the immunocompetent host lung-infiltrating CD8 T cells confine the infection in nodular inflammatory foci and prevent viral pathology. By ...
Yang Wan W Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York, United States of - - 2014
A variety of filtering methods enable the recursive estimation of system state variables and inference of model parameters. These methods have found application in a range of disciplines and settings, including engineering design and forecasting, and, over the last two decades, have been applied to infectious disease epidemiology. For any ...
Heilig Yvonne Y Institute for Biology II - Molecular Plant Physiology, Albert-Ludwigs University Freiburg, Freiburg, - - 2014
Nuclear DBF2p-related (NDR) kinases constitute a functionally conserved protein family of eukaryotic regulators that control cell division and polarity. In fungi, they function as effector kinases of the morphogenesis (MOR) and septation initiation (SIN) networks and are activated by pathway-specific germinal centre (GC) kinases. We characterized a third GC kinase, ...
Tang Ke K Department of Bioengineering, University of Illinois at Chicago, Chicago, Illinois, United States of - - 2014
Loops in proteins are flexible regions connecting regular secondary structures. They are often involved in protein functions through interacting with other molecules. The irregularity and flexibility of loops make their structures difficult to determine experimentally and challenging to model computationally. Conformation sampling and energy evaluation are the two key components ...
Cotton Laura A LA Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, - - 2014
HLA-restricted immune escape mutations that persist following HIV transmission could gradually spread through the viral population, thereby compromising host antiviral immunity as the epidemic progresses. To assess the extent and phenotypic impact of this phenomenon in an immunogenetically diverse population, we genotypically and functionally compared linked HLA and HIV (Gag/Nef) ...
Turner Joseph D JD Centre for Immunology and Infection, Department of Biology, University of York, York, United - - 2014
Circulating monocyte sub-sets have recently emerged as mediators of divergent immune functions during infectious disease but their role in helminth infection has not been investigated. In this study we evaluated whether 'classical' (CD14brightCD16-), 'intermediate' (CD14brightCD16+), and 'non-classical' (CD14dimCD16+) monocyte sub-sets from peripheral blood mononuclear cells varied in both abundance and ...
Liu Xiang X Division of Infectious Diseases, University Medicine Cluster, National University Health System, - - 2014
Melioidosis is a problem in the developing tropical regions of Southeast Asia and Northern Australia where the the Gram negative saprophytic bacillus Burkholderia pseudomallei is endemic with the risk of fulminant septicaemia. While diabetes mellitus is a well-established risk factor for melioidiosis, little is known if specific hypoglycemic agents may ...
Andreoli Arianna A Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, - - 2014
While traditionally surgery has dominated the clinical management of Buruli ulcer (BU), the introduction of the combination chemotherapy with oral rifampicin and intramuscular streptomycin greatly improved treatment and reduced recurrence rates. However management of the often extensive lesions after successful specific therapy has remained a challenge, in particular in rural ...
Brelsfoard Corey C Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, Connecticut, United States of America; Department of Natural Sciences, St. Catharine College, St. Catharine, Kentucky, United States of - - 2014
Tsetse flies (Glossina spp.) are the cyclical vectors of Trypanosoma spp., which are unicellular parasites responsible for multiple diseases, including nagana in livestock and sleeping sickness in humans in Africa. Glossina species, including Glossina morsitans morsitans (Gmm), for which the Whole Genome Sequence (WGS) is now available, have established symbiotic ...
Paradkar Prasad N PN CSIRO Animal, Food and Health Sciences, Australian Animal Health Laboratory, Geelong, Victoria, - - 2014
Despite their importance as vectors of human and livestock diseases, relatively little is known about innate antiviral immune pathways in mosquitoes and other insects. Previous work has shown that Culex Vago (CxVago), which is induced and secreted from West Nile virus (WNV)-infected mosquito cells, acts as a functional homolog of ...
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