Search Results
Results 351 - 400 of 2001
< 3 4 5 6 7 8 9 10 11 12 13 >
Pollitt Laura C LC Center for Infectious Disease Dynamics, Department of Biology, Pennsylvania State University, University Park, Pennsylvania, United States of America; Centre for Immunology, Infection and Evolution, The University of Edinburgh, Edinburgh, United - - 2014
The evolution of drug resistance, a key challenge for our ability to treat and control infections, depends on two processes: de-novo resistance mutations, and the selection for and spread of resistant mutants within a population. Understanding the factors influencing the rates of these two processes is essential for maximizing the ...
Song Yuping Y Department of Endocrinology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, - - 2014
SIRT3 is an important regulator in cell metabolism, and recent studies have shown that it may be involved in the pharmacological effects of metformin. However, the molecular mechanisms underlying this process are unclear. The effects of SIRT3 on the regulation of oxidative stress and insulin resistance in skeletal muscle were ...
Prager Sean M SM Department of Entomology, Texas A&M AgriLife Research and Extension Center, 1102 E FM 1294, Lubbock, TX 79403, - - 2014
The ecological theory on host plant choice by herbivores suggests that mothers should choose plants that will maximize their offspring's success. In annual host plants, physiology (and therefore host suitability) is sometimes influenced by maturity and growth stage, which may influence female choice. Potato plants were grown under greenhouse conditions ...
Demirel I I Department of Anesthesiology and Reanimation, Firat University, Faculty of Medicine, Elazig, Turkey. - - 2014
Just as hip prosthesis, most of the patients undergoing orthopedic lower extremity surgery (OLES) belong to the advanced age group. Sciatic nerve block combined with psoas compartment block is used as a technique alternative to central neuraxial block and GA. In geriatric patients that will undergo partial hip prosthesis, the ...
Howie Lajeana D - - 2014
Data from the National Health Interview Survey, 2011-2012 Seven and one-half percent of children aged 6-17 years used prescribed medication during the past 6 months for emotional or behavioral difficulties. A higher percentage of children insured by Medicaid or the Children's Health Insurance Program used prescribed medication for emotional or ...
Feldstain A A School of Psychology, University of Ottawa, Ottawa, ON. ; Division of Palliative Medicine, Élisabeth-Bruyère Hospital, Ottawa, - - 2014
Distress has been declared the 6th vital sign in Canadian cancer care. Accordingly, health care professionals in Canada are expected to screen for distress in patients with cancer, for which a toolkit has been developed. Identifying patients who may be in need of further resources has the potential to improve ...
Lu Cheng-Chang - - 2014
Intramedullary titanium elastic nails have been reported to fix displaced midclavicular fractures with excellent functional outcomes and minor complications. This study reports and analyzes the complications and technical pitfalls associated with titanium elastic nail fixation of displaced midclavicular fractures and describes how to prevent these problems. The authors operated on ...
Chang Yun C YC Molecular Microbiology Section, Laboratory of Clinical Infectious Diseases, NIAID, NIH Bethesda, Maryland, United States of - - 2014
Cryptococcus neoformans encounters a low oxygen environment when it enters the human host. Here, we show that the conserved Ras1 (a small GTPase) and Cdc24 (the guanine nucleotide exchange factor for Cdc42) play an essential role in cryptococcal growth in hypoxia. Suppressor studies indicate that PTP3 functions epistatically downstream of ...
Benoit Joshua B JB Department of Epidemiology of Microbial Diseases, Yale School of Public Health, Yale University, New Haven, Connecticut, United States of - - 2014
Tsetse flies undergo drastic fluctuations in their water content throughout their adult life history due to events such as blood feeding, dehydration and lactation, an essential feature of the viviparous reproductive biology of tsetse. Aquaporins (AQPs) are transmembrane proteins that allow water and other solutes to permeate through cellular membranes. ...
Sha Sha - - 2014
In this study, we used GM2/GD2 synthase knockout (GM2/GD2−/−) mice to examine the influence of deficiency in ganglioside “a-pathway” and “b-pathway” on cognitive performances and hippocampal synaptic plasticity. Eight-week-old GM2/GD2−/− male mice showed a longer escape-latency in Morris water maze test and a shorter latency in step-down inhibitory avoidance task ...
Shen Yinchen Y Department of Ophthalmology, Shanghai First People's Hospital affiliated to Shanghai Jiao Tong University, Shanghai 200080, China; Shanghai Jiao Tong University School of Medicine, Shanghai 200025, - - 2014
Diabetic macular edema (DME) is one of the major causes of visual impairment in patients with diabetes mellitus. DME shows a variety of clinical characteristics with unpredictable results to treatment. The purpose of this study was to investigate the characteristics of fundus autofluorescence (FAF) in DME, which is a rapid, ...
Li Na N Department of Ophthalmology, Navy General Hospital of Chinese People's Liberation Army, Beijing 100048, - - 2014
The aim of this review is to comprehensively and unbiasedly summarize the improvements in the techniques for classical corneal collagen cross-linking (CXL) by covering the reasons for this improvement, measure, and effect to approach the future direction of the CXL. All articles used in this review were mainly retrieved from ...
Fuentes-Contreras Eduardo E Departamento de Producción Agrícola, Facultad de Ciencias Agrarias, Universidad de Talca, Casilla 747, Talca, - - 2014
The genetic structure of adult codling moth, Cydia pomonella (L.), populations was characterized both inside a managed apple, Malus domestica Borkdhausen, orchard and in surrounding unmanaged hosts and nonhost trees in central Chile during 2006-2007. Adult males were collected using an array of sex pheromone-baited traps. Five microsatellite genetic markers ...
Sundqvist Emilie E Neuroimmunology Unit, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, - - 2014
JC polyomavirus (JCV) carriers with a compromised immune system, such as in HIV, or subjects on immune-modulating therapies, such as anti VLA-4 therapy may develop progressive multifocal leukoencephalopathy (PML) which is a lytic infection of oligodendrocytes in the brain. Serum antibodies to JCV mark infection occur only in 50-60% of ...
Lu Yi Y Department of Ophthalmology, First People's Hospital of Shanghai, Shanghai Jiao Tong University, Shanghai 200080, - - 2014
The common pathological characteristics of corneal injury include inflammatory factors activation, vascular endothelial cells or inflammatory cells infiltration into lesions, corneal edema, corneal neovascularization (CNV), and scar formation. PEDF-34 is the functional fragment of pigment epithelium-derived factor (PEDF) that has anti-angiogenic and anti-inflammatory properties and contains an N-terminal 34-amino acid ...
Sun X-Z XZ Department of Pediatrics, Huai'an First People's Hospital, Nanjing Medical University, Huai'an, P. R. China. - - 2014
The aim of this study was to investigate the effects of Rho kinase inhibitor-Fasudil on hypoxic pulmonary hypertension (HPH) and pulmonary vascular remodeling in rats. A total of 24 Sprague Dawley rats were evenly randomized into control, model and Fasudil intervention groups. Light and transmission electron microscopy were utilized to ...
Benoit Joshua B JB Division of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, Connecticut, United States of - - 2014
In tsetse flies, nutrients for intrauterine larval development are synthesized by the modified accessory gland (milk gland) and provided in mother's milk during lactation. Interference with at least two milk proteins has been shown to extend larval development and reduce fecundity. The goal of this study was to perform a ...
de Blank P P Department of Pediatrics, Division of Pediatric Hematology and Oncology, Rainbow Babies and Children's Hospital, Cleveland, OH, - - 2014
Patients with neurofibromatosis type 1 (nf1) are at increased risk for both benign and malignant tumours, and distinguishing the malignant potential of an individual tumour is a common clinical problem in these patients. Here, we review two cases of uncommon malignancies (Hodgkin lymphoma and mediastinal germ-cell tumour) in patients with ...
Kuntz Steven G SG QB3 Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, California, United States of America; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California, United States of - - 2014
Temperature affects both the timing and outcome of animal development, but the detailed effects of temperature on the progress of early development have been poorly characterized. To determine the impact of temperature on the order and timing of events during Drosophila melanogaster embryogenesis, we used time-lapse imaging to track the ...
Park Jun Hyuk JH Department of Physical Therapy, Graduate School, Silla University, Republic of - - 2014
[Purpose] The purpose of this study was to identify the effects of visual field condition on electromyography of the lower extremities during arm reaching in healthy adults, and to compare differences in electromyography of the lower extremities between young and old adults according to visual fields condition. [Subjects and Methods] ...
Chen Yanyun Y Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University; Beijing Ophthalmology & Visual Science Key Laboratory, Beijing 100730, - - 2014
With the increasing popularity of cosmetic facial filler injections in recent years, more and more associated complications have been reported. However, the causative surgical procedures and preventative measures have not been studied well up to now. The aim of this stady was to investigate the clinical characteristics and visual prognosis ...
Byun S J SJ Department of Surgery, Wonkwang University School of Medicine, Iksan, Republic of Korea. - - 2014
AMP-activated protein kinase (AMPK) is suggested to exert cytoprotective and anti-inflammatory effects in endothelial cells, but the precise mechanisms are not fully understood. It has been reported that pharmacological activation of AMPK induces endothelial heme oxygenase-1 (HO-1) expression. β-Lapachone (BL), a well-known substrate of quinone oxidoreductase (NQO1), stimulates AMPK activation ...
Attardo Geoffrey M GM Yale School of Public Health, Department of Epidemiology of Microbial Diseases, New Haven, Connecticut, United States of - - 2014
Regulation of tissue and development specific gene expression patterns underlies the functional specialization of organs in multi-cellular organisms. In the viviparous tsetse fly (Glossina), the female accessory gland is specialized to generate nutrients in the form of a milk-like secretion to support growth of intrauterine larva. Multiple milk protein genes ...
Shah Neil A NA Clarus Dermatology, Saint Anthony, - - 2014
Mondor's disease, a superficial thrombophlebitis, is a common complication of thoracoabdominal wall surgeries. While most patients experience disease resolution with expectant management, occasionally the disease may persist. The authors present a case of a 49-year-old woman who had persistent, symptomatic Mondor's disease 15 months status post-breast augmentation. The patient responded ...
Tanaka Toshio T Authors' Affiliations: Laboratory of Immune Regulation, World Premier International Immunology Frontier Research Center, Osaka University, Osaka, - - 2014
Cytokines are soluble mediators, which aid cell-to-cell communication in immune responses, and interleukin-6 (IL-6) is a prototypical cytokine featuring redundant and pleiotropic activity. The complete elucidation of the IL-6-mediated signal transduction system has provided a molecular basis for the characteristic features of cytokines. When tissue damage or inflammation due to ...
Hryniuk W W CAREpath Inc., Toronto, - - 2014
Our aim was to determine the extent to which comprehensive navigation augments the provincial health system for meeting the needs of newly-diagnosed cancer patients (clients). We also assessed reactions of attending physicians to comprehensive navigation. Clients who completed navigation as an employee benefit or through membership in an insurance organization ...
Teixeira Clarissa C Vector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America; Centro de Pesquisas Gonçalo Moniz, Fiocruz, Bahia, - - 2014
Mice exposed to sand fly saliva are protected against vector-transmitted Leishmania major. Although protection has been related to IFN- γ producing T cells, the early inflammatory response orchestrating this outcome has not been defined. Mice exposed to uninfected P. duboscqi bites and naïve mice were challenged with L. major-infected flies ...
Lee Chae-Woo CW Department of Rehabilitation Science, Graduate School, Daegu University, Republic of - - 2014
[Purpose] The purpose of this study was to examine the influence of mat Pilates and apparatus Pilates on pain and static balance of businesswomen with chronic back pain. [Subjects and Methods] Participants were randomly allocated to Pilates mat exercises (PME) or Pilates apparatus exercise (PAE), and performed the appropriate Pilates ...
Kim Chul C Department of Rehabilitation Medicine, College of Medicine, Sanggye-Paik Hospital, Inje University, Republic of - - 2014
[Purpose] This study investigated the effects of mid, and high exercise intensities on hemodynamic responses and cardiac events during two exercise types of treadmill exercise (TM) and cycle ergometer exercises (CE) in patients with acute coronary syndrome (ACS). [Subjects] Patients who had percutaneous coronary intervention (PCI) for ACS and were ...
Winslow M R - - 2014
Salvia divinorum is a psychoactive botanical plant that is increasingly used for the 'legal' highs that it can produce. It is readily available for purchase on the Internet, and most abusers are unaware of the toxicity and abuse potential associated with its use. As the use of novel compounds among ...
Jimmy Juang Jyh-Ming JJ Cardiovascular Center and Division of Cardiology, Department of Internal Medicine, Taiwan University Hospital and Taiwan University College of Medicine, Taipei, Taiwan, - - 2014
Congenital long QT syndrome (LQTS) is an ion channelopathy associated with genetic mutations. It is well known that most LQTS patients (91%) have a single mutation. The purpose of this study was to investigate the clinical characteristics of congenital LQTS patients with bigenic mutations in Taiwan, China. Congenital LQTS patients ...
Gill K A KA Department of Entomology, Iowa State University, Ames, IA 50011, - - 2014
Native plants attractive to beneficial insects may improve the value of buffer strips by increasing biodiversity and enhancing the delivery of insect-derived ecosystem services. In a 2-yr field experiment, we measured the response of insect communities across nine buffers that varied in plant diversity. We constructed buffers with plants commonly ...
Bonutti Peter M - - 2014
The current study was conducted to examine the clinical and radiographic outcomes of cementless bipolar arthroplasty in patients who had type C bone at the time of the procedure. A total of 87 patients (105 hips) who had type C femora and had undergone cementless bipolar hemiarthroplasty with a proximally ...
Neri Franco M FM Department of Plant Sciences, University of Cambridge, Cambridge, United - - 2014
Outbreaks of infectious diseases require a rapid response from policy makers. The choice of an adequate level of response relies upon available knowledge of the spatial and temporal parameters governing pathogen spread, affecting, amongst others, the predicted severity of the epidemic. Yet, when a new pathogen is introduced into an ...
Barnes Kerri T - - 2014
To determine whether ureteric stent extraction strings affect stent-related quality of life (QoL) or increase complications after ureteroscopy (URS) for stone disease. In all, 68 patients undergoing URS (October 2011 to May 2013) for stone disease were randomised to receive a ureteric stent with or without an extraction string. Patients ...
Cheng Xiaoguang X Department of Radiology, Beijing Jishuitan Hospital, Beijing 100035, - - 2014
The performance of computed tomography X-ray absorptiometry (CTXA) against the dual energy X-ray absorptiometry (DXA) as standard has not been studied in Chinese population. The aim of this study was to evaluate the precision of this measurement and validate the value of quantitative computed tomography (QCT) by comparing CTXA results ...
Cheng Chih-Hsiu CH Department of Physical Therapy and Graduate Institute of Rehabilitation Science, College of Medicine, Chang Gung University, Taiwan ; Healthy Aging Research Center, Chang Gung University, - - 2014
[Purpose] Muscle co-contraction is important in stabilizing the spine. The aim of this study was to compare cervical muscle co-contraction in adults with and without chronic neck pain during voluntary movements. [Subjects and Methods] Surface electromyography of three paired cervical muscles was measured in fifteen young healthy subjects and fifteen ...
Rodrigues Vasco V CNRS FR3636, Université Paris Descartes, Paris, France; Parasite Disease Group, Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, - - 2014
Leishmania infantum causes a chronic infectious disease named visceral leishmaniasis (VL). We employed a non-human primate model to monitor immune parameters over time and gain new insights into the disease. Rhesus macaques were infected with L. infantum and the T helper and B cell immunological profiles characterized during acute and ...
Makarawate P - - 2014
Brugada syndrome (BrS) is a common genetic cause of sudden cardiac arrest (SCA) due to polymorphic ventricular tachycardia and ventricular fibrillation. The current recommended therapy for high-risk BrS patients is the use of an implantable cardioverter defibrillator (ICD). The present study aimed to report the clinical characteristics and treatment outcomes ...
Yu Daping D Department of Medical Oncology, Beijing Chest Hospital, Capital Medical University, Beijing 101149, - - 2014
Personalized medicine becomes essential in lung cancer treatment, however lung-cancer-related gene expression profiles in Chinese patients remain unknown. In this study, the correlation of gene expression profiles and clinical characteristics in non-small-cell lung cancer (NSCLC) was investigated. Seventy-six Chinese patients with NSCLC were enrolled in the study to investigate mRNA ...
Liang B B Department of Cardiology, The Second Hospital of Shanxi Medical University, Taiyuan, China. - - 2014
ATP-binding cassette transporter A1 (ABCA1) plays a crucial role in reverse cholesterol transport and anti-atherosclerosis. Cyclic AMP (cAMP) could increase the ABCA1 expression. Angiotensin (Ang)-(1-7) can protect endothelial cells, inhibit smooth muscle cell growth, ameliorate inflammation and exert anti-atherosclerotic effects. In this study, we attempted to clarify the effect of ...
Peixoto R D RD BC Cancer Agency, Vancouver, - - 2014
In 2006, perioperative epirubicin, cisplatin, and 5-fluorouracil (ecf), compared with surgery alone, demonstrated a significant survival benefit in resectable gastroesophageal cancers. We report the results of our experience with that protocol. The BC Cancer Agency (bcca) is a multicentre institution that treats most oncology patients for the province. Characteristics of ...
Nogi Masayuki M Department of Medicine, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI - - 2014
A case of the mid-ventricular variant of takotsubo cardiomyopathy is reported, occurring in a patient with Cannabinoid Hyperemesis Syndrome (CHS), and presented with a review of the relevant literature. The patient is a 32-year-old woman who presented with epigastric pain, nausea and vomiting. Her EKG showed dynamic T-wave changes associated ...
Cha Yuri Y Department of Physical Therapy, The Graduate School, Sahmyook University, Republic of - - 2014
[Purpose] The aim of this study was to investigate the effects of tempo changes in rhythmic auditory stimulation (RAS) on gait in stroke patients. [Subjects] Forty-one chronic stroke patients who had had a stroke with more than 6 months previously were recruited for this study. [Methods] All participants were asked ...
Cho Gyeong Hee GH Department of Physical Therapy, College of Rehabilitation Science, Daegu University, Republic of - - 2014
[Purpose] The objective of this study was to determine the effects of virtual reality-based balance training on balance of the elderly. [Methods] The subjects were 32 healthy elderly people aged between 65 and 80, who were divided into a VR (virtual reality) training group (n=17) and a control group (n=15). ...
Abdullah S - - 2014
Melorheostosis is a rare, progressive bone disease accompanied by hyperostosis and soft tissue fibrosis. While affected adults present with contracture and pain, children present with limb length discrepancy and deformity. We report the case of a 20-year-old woman with melorheostosis since childhood who presented with right hand deformity and numbness. ...
Li Mingzhu M Department of Obstetrics and Gynecology, Peking University People's Hospital, Beijing 100044, - - 2014
Endometrial carcinoma is one of the most common gynecological cancers and the incidence has been increasing. This study was to identify the relationship of estrogen receptor (ER), progestrone receptor (PR), P53 protein, Ki-67 and phosphatase and tensin homolog deleted on chromosome ten (PTEN) with endometrial carcinoma, the assessment of these ...
Ozenc S S Department of Family Medicine, Department of Cardiology, and Department of Surgery, Diyarbakir Military Hospital, Yenisehir, Diyarbakir, Turkey. - - 2014
The optimal approach is controversial in asymptomatic patients who are coincidentally found to have evidence of an accessory pathway (AP) on an ECG. The risk of sudden cardiac death (SCD) is low, and the risk of developing symptoms also appears to be low, although a wide range of incidences have ...
Narod S A SA Women's College Research Institute, University of Toronto, Toronto, - - 2014
The risk of breast cancer in carriers of BRCA1 and BRCA2 mutations is influenced by factors other than the genetic mutation itself. Modifying factors include a woman's reproductive history and family history of cancer. Risk factors are more likely to be present in women with breast cancer than in women ...
Cunningham Brian - - 2014
Posterior wall acetabular fractures that involve 10% to 40% of the posterior wall may or may not require an open reduction and internal fixation. Dynamic stress examination of the acetabular fracture under fluoroscopy has been used as an intraoperative method to assess joint stability. The aim of this study was ...
< 3 4 5 6 7 8 9 10 11 12 13 >