Search Results
Results 301 - 350 of 2001
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Ebrahimzadeh M A MA Pharmaceutical Sciences Research Center, School of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran. - - 2014
Many pharmacological activities have been reported in Vicia (V.) genus. The aim of present study was to investigate antidepressant and antihemolytic activities of aerial parts of V. sojakii. Antidepressant activity of methanolic extract was evaluated by forced swimming test (FST) and tail suspension tests (TST) in male Swiss albino mice. ...
Mei-Dan Omer - - 2014
Femoral derotational osteotomy is an acceptable treatment for excessive femoral torsion. The described procedure is a minimally invasive single-incision technique based on an intramedullary saw that enables an inside-out osteotomy, preserving the periosteum and biological activity in the local bone and soft tissue. After the osteotomy is complete and correction ...
Frappier Vincent V Department of Biochemistry, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, - - 2014
Normal mode analysis (NMA) methods are widely used to study dynamic aspects of protein structures. Two critical components of NMA methods are coarse-graining in the level of simplification used to represent protein structures and the choice of potential energy functional form. There is a trade-off between speed and accuracy in ...
Possik Elite E Goodman Cancer Research Center, McGill University, Montréal, Québec, Canada; Department of Biochemistry, McGill University, Montréal, Québec, - - 2014
Dysregulation of AMPK signaling has been implicated in many human diseases, which emphasizes the importance of characterizing AMPK regulators. The tumor suppressor FLCN, responsible for the Birt-Hogg Dubé renal neoplasia syndrome (BHD), is an AMPK-binding partner but the genetic and functional links between FLCN and AMPK have not been established. ...
Li Zheng Z Department of Ophthalmology, 1st People's Hospital affiliated to Chenzhou City, Nanhua University, Chenzhou, Hunan 423000, - - 2014
Neovascular glaucoma is a refractory disease, and difficult to manage. The aim of this study was to evaluate the clinical outcomes of Ahmed glaucoma valve implantation (AGVI) in neovascular glaucoma (NVG) and non-NVG patients. This prospective, non-randomized study included 55 eyes of 55 patients with refractory glaucoma; 27 had NVG ...
Xu Jianjiang J Department of Ophthalmology, Eye, Ear, Nose, and Throat Hospital, School of Shanghai Medicine, Fudan University, Shanghai 200031, China. Email: - - 2014
This review aims to summarize the progress of current clinical studies in ocular angiogenesis treated with anti-vascular endothelial growth factor (VEGF) therapy and to discuss the benefits and challenges of the treatment. Pubmed, Embase and the Cochrane Library were searched with no limitations of language and year of publication. Clinical ...
Li Chao C Key laboratory of Entomology and Pest Control Engineering, College of Plant Protection, Southwest University, Chongqing 400716, - - 2014
Colorado potato beetle, Leptinotarsa decemlineata (Say), is the most destructive pest of potato in many countries of the world. It first invaded China from Kazakhstan in 1990s and now is a major pest of potato in many areas of Xinjiang Uygur Autonomous Region (Xinjiang). The objective of this study was ...
Schneider Francisco Santos FS Departamento de Bioquímica e Imunologia, Instituto Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, - - 2014
The snake Bothrops atrox is responsible for the majority of envenomings in the northern region of South America. Severe local effects, including hemorrhage, which are mainly caused by snake venom metalloproteinases (SVMPs), are not fully neutralized by conventional serum therapy. Little is known about the immunochemistry of the P-I SVMPs ...
Zheng Xiangzi X Department of Biochemistry, Centre for Plant Molecular Biology, Eberhard Karls University, Tübingen, - - 2014
Genome sequences of several economically important phytopathogenic oomycetes have revealed the presence of large families of so-called RXLR effectors. Functional screens have identified RXLR effector repertoires that either compromise or induce plant defense responses. However, limited information is available about the molecular mechanisms underlying the modes of action of these ...
Zhang Chi - - 2014
In vitro drug release evaluation is a very important step toward the quality control of nano- or micro-particular drug delivery systems. However, most quantitative techniques such as high-performance liquid chromatography requires a dialysis membrane to separate the released free drug from these delivery systems, thus are not capable of direct ...
Khoriati Al-Achraf - - 2014
The incidence of vascular injuries associated with total hip arthroplasty (THA) is low. However, several vascular structures are at risk of injury within the pelvis. These include the external iliac, femoral, and obturator vessels. Both reaming of the acetabulum and drilling of the acetabular screw holes may place these structures ...
Mitra Sreyoshi S Molecular Mycology Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur, Bangalore, - - 2014
Specification of the centromere location in most eukaryotes is not solely dependent on the DNA sequence. However, the non-genetic determinants of centromere identity are not clearly defined. While multiple mechanisms, individually or in concert, may specify centromeres epigenetically, most studies in this area are focused on a universal factor, a ...
Lim Kyoung Il KI Department of Physical Therapy, Kyungbuk-College, Republic of - - 2014
[Purpose] This research was designed to find out how the so-called "dynamic balance" is affected by doing different types of warm up exercises. In particular, the research is focused on the difference in the effect on dynamic Balance of warming up in water versus on the ground. [Subjects and Methods] ...
Chew C P CP Department of Orthopaedic Surgery, Singapore General Hospital, Outram Road, Singapore 169609. - - 2014
The fabella, a sesamoid bone sometimes found in the lateral head of the gastrocnemius muscle, often articulates directly with the lateral femoral condyle. This study aimed to determine the incidence of fabellae in an Asian population and to characterise the radiological features of the fabella. Electronic radiographs and magnetic resonance ...
Chiocca E Antonio EA Authors' Affiliations: Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston - - 2014
Oncolytic viruses (OV) selectively replicate and kill cancer cells and spread within the tumor, while not harming normal tissue. In addition to this direct oncolytic activity, OVs are also very effective at inducing immune responses to themselves and to the infected tumor cells. OVs encompass a broad diversity of DNA ...
Nowrangi Milap A - - 2014
Executive functioning (EF) is an important cognitive domain that is negatively affected in a number of neuropsychiatric conditions. Neuroimaging methods have led to insights into the anatomical and functional nature of EF. The authors conducted a systematic review of the recent cognitive and neuroimaging literature to investigate how the neuroimaging ...
Taniyama T K TK Department of Breast Oncology and Medical Oncology, National Cancer Center Hospital, Tokyo, - - 2014
Prediction of prognosis is important for patients so that they can make the most of the rest of their lives. Oncologists could predict survival, but the accuracy of such predictions is unclear. In this observational prospective cohort study, 14 oncologists treating 9 major adult solid malignancies were asked to complete ...
Machado Daniel D The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Horsholm, - - 2014
Constraint-based models of metabolism are a widely used framework for predicting flux distributions in genome-scale biochemical networks. The number of published methods for integration of transcriptomic data into constraint-based models has been rapidly increasing. So far the predictive capability of these methods has not been critically evaluated and compared. This ...
Mun Byeong-Mu BM Department of Rehabilitation Science, Graduate School, Daegu University, Republic of - - 2014
[Purpose] This study sought to determine the usefulness of sit to stand training in self-directed treatment of stroke patients. It examined the effect that sit to stand training has on balance and functional movement depending on the form of support surfaces. [Subjects and Methods] Thirty stroke patients were randomly sampled ...
Heo Hyo-Jin HJ Department of Rehabilitation Science, Graduate School, Inje University, Republic of - - 2014
[Purpose] The purpose of this study was to identify the effects of an inclined ankle on the activation of the abductor hallucis muscle during short foot exercises. [Subjects] We recruited 14 healthy volunteers who were free of pain, and did not suffer from arthritis or osteomuscular problems related to the ...
Ansary A A Department of Neonatology, Royal Hospital for Sick Children (Yorkhill), Dalnair Street, Glasgow G3 8SJ, United Kingdom. - - 2014
Venlafaxine, a serotonin and norepinephrine reuptake inhibitor, is increasingly used in pregnant women with pre-existing depression who require continued treatment. However, its in uteroeffects on the developing fetus are not clear. Herein, we report the unusual presentation of venlafaxine withdrawal in a female preterm baby of 29 weeks gestation, who ...
Bogod Nicholas M - - 2014
Deep brain stimulation (DBS) of the subgenual cingulate gyrus (SCG) is a promising investigational intervention for treatment-resistant depression (TRD), but long-term outcome data are limited. Serial neuropsychological evaluations, using a comprehensive battery, were conducted on four subjects with TRD prior to surgery, and up to 42 months post-operatively. Reliable change ...
Agboola A O J AO Olabisi Onabanjo University, Department of Morbid Anatomy and Histopathology, Sagamu. - - 2014
Advances in breast cancer (BC) research have demonstrated differences between black and white women with regarding tumour behaviour, patient outcome and response to treatment which can be explained by underlying genetic changes. The tumour suppressor gene p53 has been speculated to be involved in tumour biology of triple negative and/or ...
You Young Youl YY Bronco Memorial Hospital, Republic of - - 2014
[Purpose] This study investigated the effects of stretching and joint stabilization exercises applied to spastic shoulder joints on improving shoulder dysfunction in hemiplegic patients. [Subjects and Methods] Hemiplegic patients were classified into three groups: one group received 30 min of traditional exercise therapy for the spastic shoulder joint; one group received ...
Park Tae-Jin TJ Department of Design Institute, Inje University: 607 Inje-ro, Gimhae-si, Gyeongsangnam-do 621-749, Republic of - - 2014
[Purpose] The aim of the present study was to examine the influence of wobble board training on static balance, with and without vision, of adolescents with Down syndrome (DS). [Subjects] Ten adolescents with DS were recruited for this study. [Methods] Participants performed quiet standing with their eyes open and closed, ...
Chan C Y CY Department of Infectious Diseases, Singapore General Hospital, Outram Road, Singapore 169608. - - 2014
An infective aetiology, including fungal infection, should be considered in the differential diagnosis of immunocompromised patients presenting with skin lesions. Dematiaceous fungi are recognised as pathogens in organ transplant recipients. Herein, we describe a rare case of a chronic necrotising granulomatous skin lesion caused by Pyrenochaeta romeroiin a renal transplant ...
Ma Linlin L Department of Urology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China. Email: - - 2014
Advances in transplantation immunology show that the balance between dendritic cells (DCs) and their subsets can maintain stable immune status in the induction of tolerance after transplantation. The aim of this study was to investigate if DCs and DC subpopulations in recipient peripheral blood are effective diagnostic indicators of acute ...
Yilmaz A A Clinic of Neurosurgery Bayburt, Bayburt State Hospital, II, Bayburt, Turkey. - - 2014
The concern about mobile phone effects is increasing as the number of users increasing too. Different studies have different results, so this topic is still open to discussion. Aim of this report was to investigate the effects of the mobile phones on the Bcl-2 gene and p53 proteins in rat ...
Niazi M T MT Segal Cancer Centre, Department of Oncology, Division of Radiation Oncology, Jewish General Hospital, McGill University, Montreal, - - 2014
Repair of radiation-induced dna double-strand breaks is a key mechanism in cancer cell radio-resistance. The synthesized compound NU7026 specifically inhibits dna-dependent protein kinase (dna-pk) within the non-homologous end-joining repair mechanism. Earlier studies demonstrated increased radiosensitivity in dna-pk deficient cells compared with wild-type cells. In chronic leukemia cells, NU7026 appears to ...
Xia Liheng - - 2014
Controversy exists regarding the clinical outcomes of reamed vs unreamed intramedullary nailing in the treatment of closed tibial fractures. This study assessed the effects of reamed vs unreamed intramedullary nailing for closed tibial fractures. The authors searched PubMed, EMBASE, BIOSIS, and the Cochrane Controlled Trials Register for randomized and quasi-randomized ...
Liu Xiang X Division of Infectious Diseases, University Medicine Cluster, National University Health System, - - 2014
Melioidosis is a problem in the developing tropical regions of Southeast Asia and Northern Australia where the the Gram negative saprophytic bacillus Burkholderia pseudomallei is endemic with the risk of fulminant septicaemia. While diabetes mellitus is a well-established risk factor for melioidiosis, little is known if specific hypoglycemic agents may ...
Na Sang Su SS Department of Rehabilitation Science, Graduate School, Daegu University, Republic of - - 2014
[Purpose] To investigate the correlation between the effect treadmill exercise and change in serum proteins in rats with osteoarthritis, a study of proteins was carried out using a mass spectrometer. [Subjects and Methods] Rats were randomly divided into five groups. After 4 weeks of treadmill training, serum from each rat ...
Murakami Kenichi K Tohoku Bunka Gakuen University, - - 2014
[Purpose] The aim of this study was to clarify the relationship between the muscle fiber conduction velocity (MFCV) obtained during muscle twitches from evoked potentials and the dynamic characteristics of muscular tension (muscle dynamic characteristics) by manipulating deep temperature. [Subjects] Subjects were 10 healthy adult men. Their mean age was ...
Castillo R L RL Section of Dermatology, Department of Medicine, University of the Philippines-Philippine General Hospital, Taft Avenue, Manila, Philippines. - - 2014
Knowledge of both the common and atypical presentations of human immunodeficiency virus (HIV)-associated dermatoses may be helpful in arousing suspicion of HIV, especially in patients with no reported risk factors. Herein, we report the case of an otherwise healthy, nonpromiscuous 29-year-old man who presented to our institution with an eight-week ...
Leo Jennifer J University of Alberta, Edmonton, Alberta, - - 2014
Disability simulations have been used as a pedagogical tool to simulate the functional and cultural experiences of disability. Despite their widespread application, disagreement about their ethical use, value, and efficacy persists. The purpose of this study was to understand how postsecondary kinesiology students experienced participation in disability simulations. An interpretative ...
Chu Shuilian S Beijing Chao Yang Hospital, Capital Medical University, Beijing 100020, China; World Health Organization Collaborating Centre for Tobacco and Health, Beijing Institute of Respiratory Medicine, Beijing 100020, China; Department of Respiratory Medicine, Capital Medical University, Beijing 100069, - - 2014
Nicotine is primarily rsponsible for the highly addictive properties of cigarettes. Similar to other substances, nicotine dependence is related to many important brain regions, particular in mesolimbic reward circuit. This study was to further reveal the alteration of brain function activity during resting state in chronic smokers by fractional amplitude ...
Aller R R Institute of Endocrinology and Nutrition, Medicine School and Deparment of Endocrinology and Nutrition, Hospital Clinico Universitario, University of Valladolid, Valladolid, Spain. - - 2014
Hyperaminotransferasemia is an important problem in obese patients. We decide to examine the changes in hyperaminotransferasemia after weight reduction in obese patients with and without NAFLD secondary to a high monounsaturated fat vs. a high polyunsaturated fat hypocaloric diets. A population of 306 obese patients was randomly allocated to two ...
Kalogeraki A A University of Crete, Medical Faculty, Department of Pathology-Cytology, PO Box1393, Heraklion, 71110 Crete, Greece. - - 2014
Myoepithelial carcinomas exhibit a wide spectrum of cytomorphologic features and diverse clinical outcomes. As a result of their morphologic heterogeneity, they can be confused easily with many tumours. Herein we report the morphological features of myoepithelial carcinoma in a 74-year-old female clinically presenting with a parotid mass. FNAB revealed hypercellular, ...
Fine S S Peel Regional Cancer Centre, Credit Valley Hospital, Mississauga, - - 2014
Data on real-life utilization of granulocyte colony-stimulating factors (g-csfs) in Canada are limited. The objective of the present study was to describe the reasons for, and the patterns of, g-csf use in selected outpatient oncology clinics in Ontario and Quebec. In a retrospective longitudinal cohort study, a review of medical ...
Chinzei Nobuaki - - 2014
This study investigated the efficacy of tibial tubercle osteotomy (TTO) with screw fixation as part of the surgical treatment of primary complicated total knee arthroplasty (TKA) and revision TKA. From January 2000 to April 2011, 15 patients (15 knees) underwent revision TKA and 20 patients (21 knees) underwent primary TKA. ...
Kim Jung-Hyun JH Department of Physical Therapy, The Graduate School, Sahmyook University, Republic of - - 2014
[Purpose] The aim of this study was to investigate the influence of an unstable surface on trunk and lower extremity muscle activities during various types of bridging exercises. [Subjects] Thirty healthy female adults voluntarily participated in this study. [Methods] All subjects were asked to perform 3 different bridging exercises (bridging ...
Saifuddin Mustafa M University of Texas at Austin, Integrative Biology, 401 Biological Laboratories, Austin, TX 78712, - - 2014
Given that many pollinators have exhibited dramatic declines related to habitat destruction, an improved understanding of pollinator resource collection across human-altered landscapes is essential to conservation efforts. Despite the importance of bumble bees (Bombus spp.) as global pollinators, little is known regarding how pollen collection patterns vary between individuals, colonies, ...
Iizaka S S RN, PHN, PhD, Department of Gerontological Nursing/Wound Care Management, University of Tokyo, Tokyo, - - 2014
Objective: Granulation tissue colour may be an indicator for nutritional assessment in pressure ulcer (PU) care. This study evaluated the relationship between nutritional status, anaemia and diabetes, and granulation tissue colour of PUs by colour analysis of digital photographs in the clinical setting. Method: The cross-sectional study included 42 older ...
Mridha A R AR All India Institute of Medical Sciences, Department of Pathology, Ansari Nagar, New Delhi-110029, India. - - 2014
Epithelioid hemangioma (EH) is a rare benign vascular lesion of soft tissue and bone, characterized by endothelial cells with epithelioid or histiocytoid appearance. Though tubular bones, flat bones, vertebra and short bones are common sites for this lesion, the epiphyseal involvement is extremely rare. We present an unusual case of ...
Couban S S Department of Medicine, Dalhousie University, Halifax, - - 2014
Adult Philadelphia chromosome-positive (Ph+) or BCR-ABL-positive (BCR-ABL+) acute lymphoblastic leukemia (all) is an acute leukemia previously associated with a high relapse rate, short disease-free survival, and poor overall survival. In adults, allogeneic hematopoietic cell transplant in first remission remains the only proven curative strategy for transplant-eligible patients. The introduction of ...
Shim Jung-Myo JM Department of Skin and Health Care, Suseong College, Republic of - - 2014
[Purpose] The purpose of this preliminary study was to investigate the effect of manual lymph drainage (MLD) of the neck on frontal electroencephalogram (EEG) asymmetry in subjects with psychological stress. [Subjects] Thirteen subjects with psychological stress participated in the study. [Methods] Subjects received MLD of the neck for 15 min. [Results] ...
Wallach J B JB Department of Radiation Oncology, Montefiore Medical Center and the Albert Einstein College of Medicine, Bronx, NY, - - 2014
Because of common risk factors, synchronous squamous cell carcinomas of the esophagus and head and neck are common, and their concurrent presence can significantly complicate disease eradication and survival. Here, we report the case of a patient with a history of extensive tobacco and alcohol use who was diagnosed with ...
Meijer Karim A - - 2014
Synthetic cannabinoids have become a worldwide epidemic because they provide a sometimes legal, easily accessible, and presumably safe alternative to marijuana. Recently published reports have linked acute psychosis, myocardial infarctions, convulsions, self-harm, and even terrorist organizations to these designer substances. This case report outlines the first reported case of Black ...
Cotton Laura A LA Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, - - 2014
HLA-restricted immune escape mutations that persist following HIV transmission could gradually spread through the viral population, thereby compromising host antiviral immunity as the epidemic progresses. To assess the extent and phenotypic impact of this phenomenon in an immunogenetically diverse population, we genotypically and functionally compared linked HLA and HIV (Gag/Nef) ...
Kim Seong-Sik SS Graduate School of Physical Therapy, Sahmyook University, Republic of - - 2014
[Purpose] The purpose of this research was to determine the effects of a virtual reality-based yoga program on middle-aged female low back pain patients. [Subjects and Methods] Thirty middle-aged female patients who suffered from low back pain were assigned to either a physical therapy program or a virtual reality-based yoga ...
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