Search Results
Results 251 - 300 of 2001
< 1 2 3 4 5 6 7 8 9 10 11 >
Giovagnoli Stefano - - 2014
The purpose of this study was to address the effect of feedstock properties and process variables on the characteristics of antitubercular drug–palladium (Pd) containing poly(lactic) acid (PLA) microparticles (MP) obtained by spray-drying of noncolloidal particle dispersions in fast drying regime. Two different systems were compared: capreomycin–Pd (C–Pd) and ofloxacin–Pd (Ofx–Pd) ...
Cantwell Anthony L - - 2014
To assess the clinical effect of the 'prostatic urethral lift' (PUL) on lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH) through a crossover design study. Men aged ≥ 50 years with an International Prostate Symptom Score of ≥ 13, a maximum urinary flow rate (Qmax) of ≤ ...
He Zhisong Z Department of Urology, Peking University First Hospital; Institute of Urology, Peking University; National Urological Cancer Center, Beijing 100034, - - 2014
The advent of targeted therapy has proved a milestone in the history of metastatic renal cell carcinoma treatment, and several guidelines now recommend sunitinib as first- or second-line treatment. But little is known about its efficacy in Asian patients. The aim of this article was to evaluate the efficacy of ...
Lindeque Bennie - - 2014
EDUCATIONAL OBJECTIVES As a result of reading this article, physicians should be able to: 1. Understand contemporary postoperative infection rates for primary total hip arthroplasty (THA). 2. Understand the epidemiology of bacterial species responsible for postoperative primary THA infections. 3. Review current interventions to decrease the primary THA infection rate. ...
McKenna Gerald J GJ McKenna Recovery Center, Ke Ala Pono - Kaua'i, Lihue, - - 2014
Medical marijuana is currently a controversial issue in medicine. There are strong pro and con opinions but relatively little scientific data on which to base medical decisions. The unfortunate scheduling of marijuana in class I has limited research and only serves to fuel the controversy. This article will review the ...
Melam Ganeswara Rao GR Department of Rehabilitation Sciences, College of Applied Medical Sciences, King Saud University, Saudi - - 2014
[Purpose] The purpose of our study was to investigate the effect of different positions on pulmonary function test (PFT) values such as forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) of asthmatic patients .[Subjects and Methods] Thirty subjects with severe asthma aged between 20-39 years were ...
Feist Adam M AM Department of Bioengineering, University of California San Diego, La Jolla, California, United States of - - 2014
Geobacter species are of great interest for environmental and biotechnology applications as they can carry out direct electron transfer to insoluble metals or other microorganisms and have the ability to assimilate inorganic carbon. Here, we report on the capability and key enabling metabolic machinery of Geobacter metallireducens GS-15 to carry ...
Zinovyeva Anna Y AY Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of - - 2014
microRNAs function in diverse developmental and physiological processes by regulating target gene expression at the post-transcriptional level. ALG-1 is one of two Caenorhabditis elegans Argonautes (ALG-1 and ALG-2) that together are essential for microRNA biogenesis and function. Here, we report the identification of novel antimorphic (anti) alleles of ALG-1 as ...
Yang Jeongok J Division of Physical Education, College of Medical and Life Science, Silla University, Republic of - - 2014
[Purpose] The purpose of this study was to determine the effects of adjusting the scapula into its ideal position through active scapular protraction on the muscle activation and function of the upper extremity. [Subjects] Twenty female college students aged 19-21 without any physical or functional disability were the subjects of ...
Bhatia R - - 2014
Clonidine is used with local anaesthetics to improve analgesia. However, the improvement conferred when clonidine is used together with ropivacaine is controversial. Thus, the present study aimed to evaluate the improvement in analgesia when clonidine is used together with ropivacaine for supraclavicular brachial plexus block. This was a prospective, randomised, ...
Téot Luc L MD, PhD Head of Wound Healing Unit, Montpellier University - - 2014
New developments in wound management may either come from remarkable progress in science and enhanced understanding of the intimate pathophysiology of wounds, or from improvements in organisation of health care.
Khan L L University of Toronto, Toronto, - - 2014
Predictive factors of recurrence were examined in 448 non-melanoma skin cancers (72% basal cell carcinoma, 28% squamous cell carcinoma) treated with radiotherapy. The overall recurrence rate was 15.8% at a median follow-up of 18.4 months. In multivariate analysis, significant factors for recurrence were age (p = 0.0197), tumour size 2 ...
Lee Changyoung C College of Humanitas, Kyung Hee University, Republic of - - 2014
[Purpose] Little data exist on systemic training programs to improve skating abilities in ice hockey players. The purpose of this study was to evaluate the effectiveness of a complex training program on skating abilities in ice hockey players. [Methods] Ten male ice hockey players (training group) that engaged in 12 ...
Jia Xiaowei X Key Laboratory of Chemical Safety and Health, National Institute for Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing 100050, - - 2014
Chronic exposure to n-hexane can lead to peripheral neuropathy that no effective treatment regimen could be applied presently. This study investigated whether myelin protein zero (P0) protein and its antibody could be used to distinguish n-hexane intoxication and protect workers from peripheral neuropathy. We compared P0 protein and its antibody ...
Lightle D M DM Entomology Program, Oregon State University, 4017 Ag and Life Sciences Bldg., Corvallis, OR 97331, - - 2014
Amphorophora agathonica (Hottes) is the primary vector of aphid-transmitted viruses in red raspberry in the Pacific Northwest region of the United States. To better understand the biology of the aphid, we estimated the lower developmental threshold and studied the seasonal activity of A. agathonica in commercial fields in northern Washington ...
Rahmani N N Department of Surgery, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran. - - 2014
Aloe vera is a medicinal plant that promotes wound healing in burn injuries. A prospective clinical trial was conducted to evaluate the effects of a topical cream containing 0.5% Aloe vera juice powder in the treatment of chronic anal fissures. The aloe cream was applied by the patients to the ...
Wong P P Radiation Medicine Program, Princess Margaret Cancer Centre, and Department of Radiation Oncology, University of Toronto, Toronto, ON. ; Département de radio-oncologie, Centre hospitalier de l'Université de Montréal, Hôpital Notre- Dame, Montreal, - - 2014
Li-Fraumeni syndrome is an autosomal dominant disorder characterized by germline TP53 mutation and increased susceptibility to cancer. Despite certain in vitro findings and a theoretical rationale for patients with TP53 mutation to be more radiosensitive and more prone to developing radiotherapy (rt)-induced secondary malignancies, corresponding clinical data remain elusive. Here, ...
Banerjee Chaitali C Immunobiology Laboratory, Department of Zoology, University of Delhi, Delhi, - - 2014
The role of calcium (Ca2+) and its dependent protease calpain in Aeromonas hydrophila-induced head kidney macrophage (HKM) apoptosis has been reported. Here, we report the pro-apoptotic involvement of calmodulin (CaM) and calmodulin kinase II gamma (CaMKIIg) in the process. We observed significant increase in CaM levels in A. hydrophila-infected HKM ...
Zhou Liya L Department of Gastroenterology, Third Hospital of Peking University, Beijing 100191, - - 2014
Helicobacter pylori (Hp) is a common and potentially curable cause of gastric mucosa lesion. This study investigated the relationship of Hp infection with histological changes in gastric mucosa and gastric cancer in Hp-positive patients compared with Hp-eradication patients followed up for ten years. From an initial group of 1 006 ...
Flanigan David C - - 2014
The purpose of this study was to determine the sensitivity and positive predictive value of magnetic resonance imaging (MRI) in the identification of full-thickness articular cartilage defects in the porcine knee. Seventy-two full-thickness chondral defects (small or large; circular, oval, or triangular) were created in 12 porcine knees. The authors ...
Webb Charles W CW Keauhou Urgent Care Center, 78-6831 Alii Dr., Suite 418, Kailua Kona, HI - - 2014
Clinical research regarding the therapeutic benefits of cannabis ("marijuana") has been almost non-existent in the United States since cannabis was given Schedule I status in the Controlled Substances Act of 1970. In order to discover the benefits and adverse effects perceived by medical cannabis patients, especially with regards to chronic ...
Obiero George F O GF Molecular Biology and Bioinformatics Unit, International Center of Insect Physiology and Ecology (icipe), Nairobi, Kenya; South African Bioinformatics Institute (SANBI), South African MRC Bioinformatics Unit, University of the Western Cape, Bellville, South - - 2014
Tsetse flies use olfactory and gustatory responses, through odorant and gustatory receptors (ORs and GRs), to interact with their environment. Glossina morsitans morsitans genome ORs and GRs were annotated using homologs of these genes in Drosophila melanogaster and an ab initio approach based on OR and GR specific motifs in ...
Lee Jeonhyeong J Department of Physical Therapy, Daegu Health College, Republic of - - 2014
[Purpose] The purpose of this study was to compare cervical repositioning errors according to smartphone addiction grades of adults in their 20s. [Subjects and Methods] A survey of smartphone addiction was conducted of 200 adults. Based on the survey results, 30 subjects were chosen to participate in this study, and ...
Ebert Stefan S Institute for Virology and Research Center for Immunology (FZI), University Medical Center of the Johannes Gutenberg University, Mainz, - - 2014
The lungs are a noted predilection site of acute, latent, and reactivated cytomegalovirus (CMV) infections. Interstitial pneumonia is the most dreaded manifestation of CMV disease in the immunocompromised host, whereas in the immunocompetent host lung-infiltrating CD8 T cells confine the infection in nodular inflammatory foci and prevent viral pathology. By ...
Perrier Marie Josee MJ School of Kinesiology and Health Studies, Queen's University, Kingston, Ontario, - - 2014
Individuals with acquired physical disabilities report lower levels of athletic identity. The objective of this study was to further explore why athletic identity may be lost or (re)developed after acquiring a physical disability. Seven women and four men (range = 28-60 years) participated in approximately 1-hour-long semistructured interviews; data were ...
Liu Gang G Department of General Surgery, Tianjin Medical University General Hospital, Tianjin 300052, - - 2014
The incidence of chronic ulcerative colitis (CUC) in China is remarkably increasing, while little information on surgical treatment has been reported. This study aimed to completely describe and analyze the clinical outcome of restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) for CUC in China. Ninety-five consecutive patients, who suffered CUC ...
Cheng Y Y Department of Urinary Surgery, Affiliated Hospital of Luzhou Medical College in Sichuan Province, Luzhou, China. - - 2014
The purpose of this study was to identify differentially expressed genes and analysis biological processes related to renal cell carcinoma. A meta-analysis was performed using the Rank Product package of Gene Expression Omnibus datasets of renal cell carcinoma. Then Gene Ontology enrichment analyses and pathway analysis were performed based on ...
Alam Abdulkader - - 2014
The authors report two unusual cases of Bickerstaff encephalitis that presented with encephalopathy and severe agitation. Management with neuroleptics typically used for management of delirium was not effective and worsened agitation. Valproic acid was effective in treatment of agitation and well tolerated.
Chen L L University of British Columbia, Vancouver, - - 2014
Cancer survivors (css) are frequently exposed to polypharmacy, which might increase their risk of drug interactions. Our study aimed to determine the relative prevalence of potential drug interactions (pdis) among css compared with non-cancer respondents (ncrs). Self-reported prescription data from 4975 patients were extracted from the U.S. National Health and ...
Tang Ke K Department of Bioengineering, University of Illinois at Chicago, Chicago, Illinois, United States of - - 2014
Loops in proteins are flexible regions connecting regular secondary structures. They are often involved in protein functions through interacting with other molecules. The irregularity and flexibility of loops make their structures difficult to determine experimentally and challenging to model computationally. Conformation sampling and energy evaluation are the two key components ...
Alam Mohammad Murshid MM Centre for Vaccine Sciences, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, - - 2014
Multiple infections with diverse enterotoxigenic E. coli (ETEC) strains lead to broad spectrum protection against ETEC diarrhea. However, the precise mechanism of protection against ETEC infection is still unknown. Therefore, memory B cell responses and affinity maturation of antibodies to the specific ETEC antigens might be important to understand the ...
Lee Jeonhyeng J Department of Physical Therapy, Daegu Health University, Republic of - - 2014
[Purpose] The purpose of this study was to evaluate the effects of stair walking training on balance ability of chronic stroke patients. [Subjects and Methods] Forty stroke patients were allocated equally and randomly to an experimental group and a control group. The experimental group undertook 30 minutes of training therapy ...
Pina Maria Fátima - - 2014
In this study, we examine the relationship between the physical structure and dissolution behavior of olanzapine (OLZ) prepared via hot-melt extrusion in three polymers [polyvinylpyrrolidone (PVP) K30, polyvinylpyrrolidone-co-vinyl acetate (PVPVA) 6:4, and Soluplus® (SLP)]. In particular, we examine whether full amorphicity is necessary to achieve a favorable dissolution profile. Drug–polymer ...
El-Ageery S M SM Medical Microbiology and Immunology Department, Faculty  of Medicine, Mansoura University, Egypt; Medical Laboratories Technology Department, Faculty of Applied Medical Sciences, Taibah University, Saudi Arabia. - - 2014
Acinetobacter resistant to carbapenems, is one of the most frequently isolated pathogens in the hospital settings and presents a challenge to the clinician. to detect metallo-β-lactamase in A. baumannii by E-test and VIM-1 genes by PCR. A four-month prospective study was done on Forty eight carbapenem resistant A. baumannii strains that ...
Niikura Takahiro - - 2014
The authors describe a tactile surgical navigation system using custom 3-dimensional (3D) models of the bony pelvis for complex acetabular fracture surgery. The bone area of interest was extracted from the Digital Imaging and Communications in Medicine (DICOM) data of computed tomography scans. A standard triangulated language file was used ...
Maciejewski Wes W Department of Mathematics, The University of British Columbia, Vancouver, British Columbia, - - 2014
Evolutionary graph theory is a well established framework for modelling the evolution of social behaviours in structured populations. An emerging consensus in this field is that graphs that exhibit heterogeneity in the number of connections between individuals are more conducive to the spread of cooperative behaviours. In this article we ...
Metsu Sofie S Department of Medical Genetics, University of Antwerp, Antwerp, - - 2014
Folate-sensitive fragile sites (FSFS) are a rare cytogenetically visible subset of dynamic mutations. Of the eight molecularly characterized FSFS, four are associated with intellectual disability (ID). Cytogenetic expression results from CGG tri-nucleotide-repeat expansion mutation associated with local CpG hypermethylation and transcriptional silencing. The best studied is the FRAXA site in ...
Swezey Sean L SL Center for Agroecology and Sustainable Food Systems, University of California, 1156 High St., Santa Cruz, CA 95064, - - 2014
Alfalfa trap crops are currently used to manage Lygus spp. in organic strawberry fields on the California Central Coast. The retention of Lygus spp. in alfalfa creates aggregated distributions that provide improved opportunities for biological control by the introduced parasitoid Peristenus relictus (Ruthe). The abundance and distribution of P. relictus ...
L Goodman B B MPH, Louis Stokes Cleveland Department of Veterans Affairs Medical Center (LSCDVAMC), Cleveland, Ohio, US. Department of Epidemiology & Biostatistics, Case Western Reserve University, Cleveland, Ohio, - - 2014
Objective: Repeated hospital admissions (RHA) for ongoing pressure ulcer (PU) care remains a significant challenge in the clinical management of the spinal cord injury/disorders (SCI/D) population. The current study investigated the significance of risk factors for PU treatment and RHA. Method: A retrospective chart review of veterans admitted to the ...
Kamaluddin M R MR Universiti Sains Malaysia, School of Health Sciences, Forensic Sciences Programme, 16150 Kubang Kerian, Kelantan, Malaysia. - - 2014
Murder is the most notorious crime that violates religious, social and cultural norms. Examining the types and number of different killing methods that used are pivotal in a murder case. However, the psychological traits underlying specific and multiple killing methods are still understudied. The present study attempts to fill this ...
Bombard Y Y University of Toronto, Toronto, ON. ; Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, - - 2014
Determining the likely benefit of adjuvant chemotherapy for early-stage breast cancer patients depends on estimating baseline recurrence risk. Gene expression profile (gep) testing of tumours informs risk prediction, but evidence of its clinical utility is limited. We explored patient perceptions of gep testing and the impact of those perceptions on ...
Sugaya Hisashi - - 2014
The goal of this study was to quantify the frequency of advanced spinal epidural lipomatosis (SEL) detected on lumbar magnetic resonance imaging (MRI) scans performed at the authors' hospital and to compare the frequency, cause, and progression of SEL in these cases with that reported in the literature. The total ...
Fatumo Segun A SA H3Africa Bioinformatics Network (H3ABioNet) Node, National Biotechnology Development Agency (NABDA), Federal Ministry of Science and Technology (FMST), Abuja, Nigeria; Human Genetics Department, Wellcome Trust Sanger Institute, Cambridge, United Kingdom; International Health Research Group, Department of Public Health & Primary Care, University of Cambridge, Cambridge, United - - 2014
Over the past few decades, major advances in the field of molecular biology, coupled with advances in genomic technologies, have led to an explosive growth in the biological data generated by the scientific community. The critical need to process and analyze such a deluge of data and turn it into ...
Lee Kyoung Jin KJ Department of Physical Therapy, Sahmyook University, Republic of - - 2014
[Purpose] The aim of the study was to assess the effect of an 8-week balance exercise program for enhancement of gait function on temporal and spatial parameters of school aged children with intellectual disabilities. [Subjects] Forty young people with intellectual disabilities were assigned either to the balance exercise program for ...
He Xinliang X Department of Respiratory and Critical Care Medicine, Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, - - 2014
Allergic asthma is a chronic airway inflammatory disease partly characterised by high concentration of T help 2 (Th2) cytokines in bronchoalveolar lavage fluid (BALF). There is no report on the relation of peripherally circulating blood lymphocytes and asthma. We explored the balance of Th2/Th1 cytokines in asthmatic mice. Exogenous recombinant ...
Xu R R Department of Anesthesiology, Ninth People's Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China. - - 2014
This study aims to evaluate the effect of sevoflurane anesthesia on myocardium in cardiac surgery and provide evidence for clinical anesthesia practice. Literature about the protective effect of sevoflurane anesthesia on myocardium in cardiac surgery published before March, 2012 was retrieved from the database of PubMed and EMBASE. The quality ...
Bredeson C C The Ottawa Hospital Research Institute, and Department of Medicine, University of Ottawa, Ottawa, - - 2014
Is there a benefit associated with the use of extracorporeal photopheresis (ecp) compared with other treatment options for patients who have received allogeneic stem-cell transplantation (sct) and are experiencing graft-versus-host disease (gvhd), if response rate, survival, or improvement in symptoms are the outcomes of interest? After allogeneic sct, gvhd is ...
Fitzgibbons Peter G - - 2014
Historically, the published literature on "terrible triad" injuries has shown a high rate of unacceptable results. The use of systematic treatment protocols may improve functional outcome. The authors performed a retrospective study of all patients aged 18 years or older who underwent surgical treatment for "terrible triad" elbow fracture dislocation ...
Deshong Alison J AJ Department of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, California, United States of - - 2014
Meiotic chromosome segregation relies on homologous chromosomes being linked by at least one crossover, the obligate crossover. Homolog pairing, synapsis and meiosis specific DNA repair mechanisms are required for crossovers but how they are coordinated to promote the obligate crossover is not well understood. PCH-2 is a highly conserved meiotic ...
Nsoesie Elaine O EO Children's Hospital Informatics Program, Boston Children's Hospital, Boston, Massachusetts, United States of America; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, United States of America; Network Dynamics and Simulation Science Laboratory, Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, Virginia, United States of - - 2014
Hantavirus pulmonary syndrome (HPS) is a life threatening disease transmitted by the rodent Oligoryzomys longicaudatus in Chile. Hantavirus outbreaks are typically small and geographically confined. Several studies have estimated risk based on spatial and temporal distribution of cases in relation to climate and environmental variables, but few have considered climatological ...
< 1 2 3 4 5 6 7 8 9 10 11 >