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Results 651 - 700 of 2001
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Unterman Avraham - - 2014
Physicians are often insufficiently trained in bedside teaching and mentoring skills. To develop, implement and assess a simulation-based training program designed to improve clinical teaching among physicians. We developed a one-day tutor training program based on six simulated scenarios with video-based debriefing. The program's efficacy was assessed using questionnaires completed ...
Bouten Carlijn Vc CV Department of Biomedical Engineering and Institute for Complex Molecular Systems, Eindhoven University of Technology, PO Box 513, 5600 MB Eindhoven, The - - 2014
  Serpooshan V, Zhao M, Metzler SA et al. The effect of bioengineered acellular collagen patch on cardiac remodeling and ventricular function postmyocardial infarction. Biomaterials 34, 9048-9055 (2013). The decline of cardiac function in the post-myocardial infarcted (MI) heart is due to two essential problems: massive loss of contractile cardiomyocytes, ...
Moon Jun-Gyu - - 2014
Minimally invasive plate osteosynthesis (MIPO) has been used for humeral shaft fractures, but concerns exist about soft tissue injuries. The purpose of this study was to report the surgical technique and clinical outcomes of MIPO using a helical plate for metadiaphyseal complex humeral shaft fractures. Twelve patients with acute displacement ...
Salerno C C Department of Translational Medicine, University of Eastern Piedmont "Amedeo Avogadro, Novara, - - 2014
We performed a geographic analysis study on mortality in the town of Vercelli, in order to respond to the concerns of the population and some local administrators. Main reason to carry out a detailed and sophisticated study for a city of medium-small size was represented by the presence of various ...
Minandri Fabrizia F Department of Sciences, University "Roma Tre", Viale Guglielmo Marconi 446, 00146 Rome, - - 2014
Gallium has a long history as a diagnostic and chemotherapeutic agent. The pharmacological properties of Ga(III) rely on chemical mimicry; when Ga(III) is exogenously supplied to living cells it can replace Fe(III) within target molecules, thereby perturbing bacterial metabolism. Ga(III)-induced metabolic distresses are dramatic in fast-growing cells, like bacterial cells. ...
Kumar Anıl N AN Kidwai Memorial Institute of Oncology, Department of Medical Oncology, Karnataka, - - 2014
Eosinophilia associated with FIP1L1-PDGFRA rearrangement represents a subset of chronic eosinophilic leukemia and affected patients are sensitive to imatinib treatment. This study was undertaken to learn the prevalence and associated clinicopathologic and genetic features of FIP1L1-PDGFRA rearrangement in a cohort of 26 adult patients presenting with profound eosinophilia (>1.5x10(9)/L). Reverse-transcriptase ...
Duan Hao-Qing HQ College of Laboratorial Medicine and College of Life Sciences, Wenzhou Medical University, Wenzhou 325035, Zhejiang Province, China; Department of Clinical Laboratorial Examination, Chinese PLA General Hospital, Bejing 100853, - - 2014
This study was purposed to investigate the antitumor effect of oridonin on human multiple myeloma cell line U266 and its possible mechanism. The CCK-8 test was used to determine the inhibitory effect of oridonin on proliferation of U266 cells. The morphological changes of U266 cells were observed under optical microscope. ...
Xiong Jingshu J Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing 210042, - - 2014
To improve the clinicopathological understanding of blastic plasmacytoid dendritic cell neoplasm (BPDCN). A total of 7 BPDCN patients were recruited from 2009 to 2013. And their clinicopathological and immunohistological features, treatment and prognosis were retrospectively analyzed. There were 6 males and 1 female. The median age range was 60 (6-72) ...
Rojas-Martínez Augusto A Facultad de Medicina and Centro de Investigación y Desarrollo en Ciencias de la Salud, Universidad Autónoma de Nuevo León, Monterrey, Mexico - - 2014
Latin America and the Caribbean region make up one of the largest areas of the world, and this region is characterized by a complex mixture of ethnic groups sharing Iberian languages. The area is comprised of nations and regions with different levels of social development. This region has experienced historical ...
Zhou Ping P Department of Hematology, Pediatrics Hospital Affiliated to Suzhou University, Suzhou 215003, Jiangsu Province, - - 2014
This study was purposed to explore the effectiveness of mixed transplantation of HLA mismatched bone marrow hematopoietic stem cells(HSC), peripheral blood HSC and umbilical cord blood HSC for treatment of pediatric blood diseases. From August 2012 to December 2012, five children with refractory hematological diseases in our hospital received allogeneic ...
Thibault Pascale - - 2014
A study was carried out in 2010-2011 to assess the effectiveness of "conscious touch" in preventing the pain caused by the removal of the Redon drain in patients having undergone a hip replacement. The results show that the pain rating is significantly lower in patients having received this touch. This ...
Gelao Lucia L Division of Early Drug Development for Innovative Therapies, Istituto Europeo di Oncologia, Via Ripamonti 435, 20141 Milan, - - 2014
Recent evidence suggests that the immune system is involved in the carcinogenesis process and the antitumor immune responses impact the clinical outcome, thus emphasizing the concept of cancer immune surveillance. In this context, dendritic cells (DCs) seem to play a crucial role, as they are the most potent antigen-presenting cells ...
Vosseller J Turner - - 2014
Injury to the tibiofibular syndesmosis can occur with ankle sprain or fracture. The incidence of syndesmotic injury has not been specifically studied at a population level. Data on syndesmotic injury were obtained from the Healthcare Cost and Utilization Project (HCUP), a federal-state-private partnership. It is administered by the Agency for ...
Xi Chao-Yun CY Department of Blood Transfusion, Chinese PLA General Hospital, Beijing - - 2014
This study was aimed to develop a new generation of ideal hemostatic powder which can be safely, effectively and easily used mainly to first aid anterior to hospital by the synergistic effect of physical and chemical hemostatic mechanisms. The tranexamic acid(TA)-loaded porous starch(PS) (TAPS) was prepared by using PS as ...
Poirot Catherine - - 2014
The survival rate after cancer is increasing and the side effects of the treatments on fertility can be anticipated. Various techniques exist for men, women as well as for children.
Iacoviello Licia L Unit of Molecular & Nutritional Epidemiology, Department of Epidemiology & Prevention, IRCCS Istituto Neurologico Mediterraneo Neuromed, Pozzilli, - - 2014
  Biobanks for medical research are organized collections of biological samples associated with personal data and information on their donors, to be stored for an indefinite period of time. The storage of biological samples has varied considerably over time, ranging from the informal storage of tissue specimens in a researcher's ...
Sun Lai-Qing - - 2014
The purpose of this study was to investigate whether pre- to postoperative changes of increased signal intensity (ISI) of the spinal cord as seen on T2-weighted magnetic resonance imaging (MRI) reflect the surgical outcome in patients with cervical spinal cord injury without radiologic evidence of trauma (SCIWORET). In this study, ...
Li Hong H Department of Cell Biology, Institute of Basic Medical Sciences, Academy of Military Medical Sciences,Beijing 100850, - - 2014
Mesenchymal stem cells (MSC) have the capacities of low immunogeneity, multiple differentiation, hemotopoitic supporting and immunoregulation. And due to their relative ease of availability and ex vivo expansion, the applications of MSC in the prevention and treatment of clinical disease have been rapidly expanded in the recent years. However, increasing ...
Han Yoo Min YM Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, - - 2014
Splenic artery pseudoaneurysms can be caused by pancreatitis, trauma, or operation. Traditionally, the condition has been managed through surgery; however, nowadays, transcatheter arterial embolization is performed safely and effectively. Nevertheless, several complications of pseudoaneurysm embolization have been reported, including coil migration. Herein, we report a case of migration of the ...
Ye Qi-Xiang QX Department of Pediatrics, SUN Yat-Sen Memorial Hospital, SUN Yat-Sen University, Guangzhou 510120, Guangdong Province, China. - - 2014
The aim of this study was to investigate the effects of CD4(+)CD25(+) regulatory T cells (Treg) on allogeneic hematopoietic stem cell transplantation (HSCT) in sensitized mice so as to provide experimental evidence for clinical treatment of allogeneic HSCT rejection in sensitized recipients. The BALB/c mice were divided into 5 groups: ...
Fouchard Anne - - 2014
Cancer leads to financial and social insecurity for those suffering from the disease. Cancer plans include this public health issue, developing support programmes to help patients preserve their social life despite the disease. A project led by a hospital's social services department helps patients in their return to work.
Smorgick Yossi - - 2014
This study was a retrospective radiographic study involving analysis of computed tomography scans obtained for patients with degenerative spondylolisthesis of the L4-L5 segment and a control group. The purpose of the study was to identify radiological predisposing factors for degenerative spondylolisthesis of the L4-L5 segment. The authors reviewed all computed ...
Oliveira Vanessa - - 2014
Salt marsh sediments are sinks for various anthropogenic contaminants, giving rise to significant environmental concern. The process of salt marsh plant survival in such environment is very intriguing and at the same time poorly understood. The plant–microbe interactions may play a key role in the process of environment and in ...
Rudert M J - - 2014
Various techniques exist for quantifying articular contact stress distributions, an important class of measurements in the field of orthopaedic biomechanics. In situations where the need for dynamic recording has been paramount, the approach of preference has involved thin-sheet multiplexed grid-array transducers. To date, these sensors have been used to study ...
Kim Byung Chul BC Department of Internal Medicine, Chungbuk National University College of Medicine, Cheongju, - - 2014
Most infants with repaired gastroschisis develop normally and remain in good health. About 10% of patients with gastroschisis have other malformations. We report a case of choledocholithiasis and intestinal malrotation in an adolescent with repaired gastroschisis. A 17-year-old girl presented with fever, jaundice, and abdominal pain. She had undergone an ...
Han Zhaolong - - 2014
To investigate air puff induced corneal vibrations and their relationship to the intraocular pressure (IOP), viscoelasticity, mass, and elasticity of the cornea based on theoretical simulations and preliminary clinical observations. To simulate the corneal movement during air puff deformation, a kinematic viscoelastic corneal model was developed involving the factors of ...
Nie Xiang-Min XM HLA Typing Laboratory of China Marrow Donor Program, Blood Center of Shandong Province, Jinan 250014, Shandong Province, - - 2014
This study was aimed to identify a novel HLA-DRB1 allele from a Chinese potential hemopoietic stem cell donor of Northeast China. A rare HLA-DRB1 allele was initially detected by Luminex PCR-SSO typing, then the sample was sequenced by sequence-based typing (SBT) and the alignments of sample's alleles was identified by ...
Dongworth Rachel K RK The Hatter Cardiovascular Institute, University College London, 67 Chenies Mews, London, - - 2014
Mitochondria are critical for sustaining life, not only as the essential powerhouses of cells but as critical mediators of cell survival and death. Mitochondrial dysfunction has been identified as a key perturbation underlying numerous pathologies including myocardial ischemia-reperfusion injury and the subsequent development of impaired left ventricular systolic function and ...
Vaidya Rahul - - 2014
An institutional review board-approved retrospective study was performed at a level 1 trauma center to evaluate the adequacy of current treatment guidelines in the management of humerus fractures following civilian gunshot injuries. Fifty-four patients with a humerus shaft fracture from a low-velocity gunshot wound were included in the study. Twenty-nine ...
Vinciguerra Paolo - - 2014
To evaluate a new curvature gradient topography map to predict postoperative corneal remodeling. In this retrospective study, 32 eyes of 16 patients with myopia underwent excimer ablation surgery with a postoperative high curvature gradient. The new curvature gradient map (acquired immediately postoperatively) shows the difference between the curvatures of two ...
Wang Xiao-Qing XQ Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Province, - - 2014
This study was aimed to investigate a more convenient and efficient method to cultivate the human bone marrow mesenchymal stem cells by means of natural erythrocyte sedimentation principle, based on the whole bone marrow adherent method. The bone marrow was cultured with a six-well plate instead of the flasks.Firsly, the ...
Aît-Kaci Fazya - - 2014
Patients suffering from cancer generally see their sex life deteriorate. Their self-image, the way their body is seen and their relationships with others are profoundly changed. Inviting the patient to evoke their difficulties helps them to regain a fulfilling sex life despite the disease.
Tulloh Robert Mr RM Department of Congenital Heart Disease, Bristol Royal Hospital for Children & Bristol Heart Institute, Bristol, BS2 8BJ, - - 2014
Respiratory syncytial virus (RSV) is a common infection, causing bronchiolitis in over 70% of infants each year and almost all children by the age of 2. It is the leading cause of acute lower respiratory tract infections and admissions to hospital worldwide. Previously healthy infants may have a prolonged cough ...
Kammar Haguy - - 2014
Sural nerve injury is a relatively common complication after surgery on the Achilles tendon. Studies to determine the course of the sural nerve have been performed on cadaveric specimens. The purpose of this cross-sectional study was to use ultrasound to determine the relations of the sural nerve in a healthy ...
Altamia Marvin A - - 2014
Teredinibacter turnerae is a cultivable intracellular endosymbiont of xylotrophic (woodfeeding)bivalves of the Family Teredinidae (shipworms). Although T. turnerae has been isolated from many shipworm taxa collected in many locations, no systematic effort has been made to explore genetic diversity within this symbiont species across the taxonomic and geographical range of ...
Li Chan-Juan CJ Department of Hematology, Tianjin Medical University Cancer Institue and Hospial, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Thearpy, Tianjin 300060, - - 2014
CAL-101 is a selective inhibitor of the phosphatidylinositol-3 kinase (PI3K), it inhibits the survival, proliferation and migration of tumor cells by directly inducing apoptosis and inhibiting micro-environmental interactions. It has been determined that the P110δ isoforms of PI3K expressed primarily in cells of hematopoietic lineage, such as B and T ...
Penchaszadeh Victor B VB Departmento de Ciencias de la Salud, Universidad Nacional de La Matanza, Buenos Aires, Argentina - - 2014
Over the past three decades, there has been an accelerated development of genetic technology, leading to its use in human genetic identification for many purposes. Additionally, it has been made explicit that identity is a fundamental human right. A number of historical circumstances have connected these developments. Personal identity is ...
Wang Yan Y Department of Hematology, The Second Hospital of Hebei Medical University, Hebei Province Key Laboratory of Blood Disease, Shijiazhuang 050000, Hebei Province, - - 2014
In order to enhance the understanding of thrombotic thrombocytopenic purpura (TTP), the clinical features, laboratory characteristics, treatment and outcome of 14 patients with TTP were retrospectively analyzed and investigated. The results showed that 7 out of 14 patients with TTP had predisposing factors, such as pregnancy in 4 cases, infection ...
Goldberg Ilan - - 2014
Erythema nodosum and pyoderma gangrenosum are common skin manifestations in inflammatory bowel diseases. Curiously, these two cutaneous features have seldom been reported to occur simultaneously. We present three patients affected with inflammatory bowel disease with concomitant erythema nodosum and pyoderma gangrenosum.
Murdaca Giuseppe G Department of Internal Medicine, Clinical Immunology Unit, University of Genova, Viale Benedetto XV, n. 6, 16132 Genova, - - 2014
Systemic sclerosis (SSc) is a rare connective tissue disease characterized by chronic inflammation and fibrosis of the skin, vascular abnormalities and variable involvement of organs. TNF-α has a central role in initial host response to infections and in the pathogenesis of various systemic immune-mediated diseases. Serum levels of TNF-α are ...
Sullivan Matthew P - - 2014
Geriatric acetabular, pelvis, and subtrochanteric femur fractures are poorly understood and rapidly growing clinical problems. The purpose of this study was to describe the epidemiologic trends of these injuries as compared with traditional fragility fractures about the hip. From 1993 to 2010, the Nationwide Inpatient Sample (NIS) recorded more than ...
Sancini A A Department of Anatomy, Histology, Medical-Legal and the Orthopedics, Unit of Occupational Medicine, Sapienza University of Rome, - - 2014
High doses of organic solvents can cause hepatic disease. We investigated whether exposure to low doses of solvents in automotive and industrial workers may lead to changes in liver tests. We studied the liver parameters (glutamic oxaloacetic transaminase (GOT), glutamic-pyruvic transaminase (GPT), gamma-glutamyl-traspeptidasi (γ-GT), alkaline phosphatase (PHA), total (TB) and ...
Macinnes Andrew A Dundee Dental Hospital, Dundee, Scotland, - - 2014
Data sourcesCochrane Oral Health Group's Trials Register, CENTRAL, Medline via PubMed and EMBASE; no restrictions on language, published before February 1st 2013.Study selectionObservational studies reporting outcomes from irradiated and non-irradiated patients were eligible for inclusion as were randomised controlled trials (RCTs) and controlled clinical trials (CCTs) assessing irradiated patients submitted ...
Castilla Eduardo E EE Instituto Nacional de Genética Médica Populacional, Latin American Collaborative Study of Congenital Malformations, Center for Medical Education and Clinical Research, Buenos Aires, Argentina - - 2014
Here we propose a registration process for population genetic isolates, usually geographic clusters of genetic disorders, based on the systematic search of rumors, defined as any type of account regardless of its reliability. Systematically ascertained rumors are recorded, and validated through a progressive process of pre-established steps. This paper outlines ...
Guo Jing J Department of Hematology, The Affiliated Hospital of Medical College, Qingdao University, Qingdao 266000, Shandong Province, - - 2014
This study was aimed to investigate the effects of the DNA methylation inhibitor 5-aza-2'-deoxycytidine (5-Aza-CdR) and histone deacetylase inhibitor trichostatin A (TSA) on DLC-1 gene transcription regulation and molecular biological behaviours in the human multiple myeloma RPMI-8226 cells. The cells were treated respectively with 5-Aza-CdR and TSA alone, or the ...
Feng Yuejing Y Department of Respiratory Diseases, First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, - - 2014
To detect the serum protein expressions of histone deacetylase 1 (HDAC1) and DNA methyltransferase 1 (DNMT1) in patients with non-small-cell lung cancer and explore the correlation between their expressions and clinicopathological features. Enzyme-linked immunosorbent assay (ELISA) was used to measure the protein expressions of HDAC1 and DNMT1 in 136 lung ...
Qumseya Bashar B Department of Gastroenterology and Hepatology, Mayo Clinic Florida, Jacksonville, FL, - - 2014
Stricture formation is a common complication after endoscopic mucosal resection. Predictors of stricture formation have not been well studied. We conducted a retrospective, observational, descriptive study by using a prospective endoscopic mucosal resection database in a tertiary referral center. For each patient, we extracted the age, sex, lesion size, use ...
Wakabayashi Hideyuki H Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Nippon Medical School, Tokyo, - - 2014
We report an extremely rare case of primary squamous cell carcinoma of the stomach. A 69-year-old man was admitted to our hospital with a 2-month history of dysphagia and tarry stools. Endoscopic examination revealed a cauliflower-shaped protruding mass along the lesser curvature of the gastric cardia. Biopsy of the lesion ...
Li De-Guan DG Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College; Tianjin Key Laboratory of Molecular Nuclear Medicine, Tianjin 300192, - - 2014
The aim of this study was to investigate the effects of D-methionine (D-met) on the hematopoietic system injury in irradiated mice. C57BL/6 mice were divided into control group, irradiated group, 300 mg/kg D-met plus irradiation group and 1000 mg/kg D-met plus irradiation group. The control mice received sham irradiation, and ...
Carreño Leandro J LJ Department of Microbiology & Immunology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, - - 2014
Abstract NKT cells are a subpopulation of T lymphocytes with phenotypic properties of both T and NK cells and a wide range of immune effector properties. In particular, one subset of these cells, known as invariant NKT cells (iNKT cells), has attracted substantial attention because of their ability to be ...
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