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Li Xin X Department of Pharmacology (Key Laboratory of Cardiovascular Medicine Research, Ministry of Education; State-Province Key Laboratories of Biomedicine-Pharmaceutics of China), Harbin Medical University, Harbin, Heilongjiang, - - 2014
Beta-adrenoceptor (β-AR) exerts critical regulation of cardiac function. MicroRNAs (miRNAs) are potentially involved in a variety of biological and pathological processes. This study aimed to investigate the role of miRNA let-7e in the up-regulation of β1 -AR and arrhythmogenesis in acute myocardial infarction (AMI) in rats. β1 -AR expression was ...
Gonçalves Oscar F OF Department of Counseling and Applied Educational Psychology, Bouvé College of Health Sciences, Northeastern University, 404 Int'l Village, Boston, MA, 02115, USA, - - 2014
Several studies have shown that basic emotions are responsible for a significant enhancement of early visual processes and increased activation in visual processing brain regions. It may be possible that the cognitive uncertainty and repeated behavioral checking evident in Obsessive Compulsive Disorder (OCD) is due to the existence of abnormalities ...
Kluge Sebastian S Department of Hand Surgery, Schulthess Clinic, Lengghalde 2, 8008, Zurich, Switzerland, - - 2014
Proximal row carpectomy (PRC) is an established surgical procedure used to treat post-traumatic osteoarthritis of the wrist with sparing of the midcarpal joint and advanced aseptic necrosis such as lunatomalacia. Proximalization of the distal carpal row following PRC may lead to secondary problems such as radiocarpal impingement. At follow-up, two ...
Zhang Min M Cancer Center, Department of Pathology, Nanjing Medical University, 140 Hanzhong Road, Nanjing, 210029, People's Republic of China, - - 2014
Our previous studies showed that prostaglandin E2 (PGE2) promotes hepatoma cell growth and migration, as well as invasion; however, the precise mechanism remains elusive. Snail and p65 protein levels were detected in human samples with hepatocellular carcinoma (HCC) by immunohistochemistry (IHC) staining. HCC cell lines (Huh-7 and Hep3B) were used ...
Miao Li-Jun LJ Department of Respiratory Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, - - 2014
Recent studies have shown that Beclin 1, a key regulator of autophagic process, is frequently downregulated and may serve as an independent prognostic biomarker for nonsmall cell lung cancer. However, the molecular mechanisms underlying its downregulation remain poorly understood. The signal transducer and activator of transcription 3 (Stat3) is a ...
Wen Shan-Yun SY Department of Obstetrics and Gynecology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, 600 Yisan Road, Shanghai, 200233, People's Republic of - - 2014
Endometrial cancer (EC) is one of the most common female malignancies. The patients with high-risk factors may have poor prognosis. Therefore, there is an urgent need to find a new molecule to more accurately predict survival of patients. Leucine-rich-alpha-2-glycoprotein1 (LRG1), one of leucine-rich repeat family, was closely associated with cancer ...
Santos Juliana I JI Molecular Oncology Group, Portuguese Institute of Oncology of Porto, Rua Dr. António Bernardino de Almeida, Porto 4200-072, - - 2014
Prostate cancer (PC) is the more frequently diagnosed neoplasia in men in developed countries. The evolution of PC to castration-resistant prostate cancer (CRPC) represents real problems of clinical management, in consequence to the limited therapeutic options. MicroRNAs (miRNAs) are small noncoding RNAs that play an important role in gene expression ...
Wang Ziliang Z Cancer Institute, Fudan University Shanghai Cancer Center, Shanghai, - - 2014
Emerging evidences show that interleukin-8 (IL-8) has important regulatory functions in tumorigenesis. IL-8 -251A/T is a single nucleotide polymorphism in the promoter region of the IL-8 gene and affects IL-8 production. Analysis of previous studies on the association of -251A/T polymorphism with different cancer types remained to be illustrated. To ...
Suys Tamarah T Neuroscience Critical Care Research Group, Department of Intensive Care Medicine, Centre Hospitalier Universitaire Vaudois (CHUV), University Hospital and Faculty of Biology and Medicine, University of Lausanne, Rue du Bugnon 46, 1011, Lausanne, - - 2014
Sedation and therapeutic hypothermia (TH) delay neurological responses and might reduce the accuracy of clinical examination to predict outcome after cardiac arrest (CA). We examined the accuracy of quantitative pupillary light reactivity (PLR), using an automated infrared pupillometry, to predict outcome of post-CA coma in comparison to standard PLR, EEG, ...
Tadwalkar Rigved R Cedars Sinai Heart Institute, Cedars Sinai Medical Center, 8631 West Third Street, Ste, 1017 East, Los Angeles, CA, 90048, - - 2014
To ascertain the beneficial role of spiritual counseling in patients with chronic heart failure. This is a pilot study evaluating the effects of adjunct spiritual counseling on quality of life (QoL) outcomes in patients with heart failure. Patients were assigned to "religious" or "non-religious" counseling services based strictly on their ...
Song J J Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, Hubei, - - 2014
Narrow band imaging (NBI) is a real-time imaging technique. The aim of this meta-analysis was to estimate the sensitivity, specificity, and diagnostic accuracy on the role of NBI in the detection and characterization of specialized intestinal metaplasia (SIM), high-grade dysplasia (HGD) in the Barrett's esophagus. We identified studies by performing ...
Mogo César C Centro de Investigação em Química do Algarve Universidade do Algarve, - - 2014
READY (REActive DYnamics) is a program for studying reactive dynamic systems using a global potential energy surface (PES) built from previously existing PESs corresponding to each of the most important elementary reactions present in the system. We present an application to the combustion dynamics of a mixture of hydrogen and ...
Imamura Yoshiomi Y Department of Psychiatry, Faculty of Medicine, Saga University, Saga, Japan; Institute of Comparative Studies of International Cultures and Societies, Kurume University, Kurume, Fukuoka, - - 2014
Research has found that spirituality/religiosity has a salutary association with mental/physical health. However, the association of belief in life after death with well-being has rarely been studied, and the same is true of its association with biological indices, such as monoamine transmitters. Therefore, we examined the associations between well-being and ...
Makimoto Kiyoko K Division of Health Sciences, Osaka University Graduate School of Medicine, Suita, - - 2014
This study presents an integrative literature review on sexuality among elderly people with dementia living in nursing homes. Original research studies published from 1980 to 2012 were included in the review. Sexual expressions ranged from holding hands to sexual intercourse. These behaviours were sometimes directed towards caregivers while the latter ...
M den Harder Annemarie A Department of Radiation Oncology, University Medical Center Utrecht, Heidelberglaan 100, 3584, Utrecht, The - - 2014
To investigate whether magnesium oxide reduces the interfraction motion of the prostate and the amount of rectal filling and rectal gas, which influences prostate position during radiotherapy for prostate cancer. From December 2008 to February 2010, 92 prostate cancer patients scheduled for intensity-modulated radiotherapy (77 Gy in 35 fractions) using fiducial ...
Garip Y Y Department of Physical Medicine and Rehabilitation, Basak Medical Center, Istasyon Mah Ayas Cad no 60 Sincan, Ankara, Turkey, - - 2014
Osteomalacia is a metabolic bone disorder characterized by impaired mineralization of bone matrix. Symptoms of osteomalacia can be confused with other conditions such as spondyloarthropathy, polymyalgia rheumatica, polymyositis, and fibromyalgia. In this case, we report a patient with axial osteomalacia who developed low back pain, morning stiffness, and "grade 3 ...
Romero Ariadna Blanca AB Institute of Energy and Climate Research, Nuclear Waste Management and Reactor Safety, Forschungszentrum Jülich, Wilhelm-Johnen-Strasse, 52428, Jülich, Germany; JARA High-Performance Computing, Schinkelstrasse 2, 52062, Aachen, - - 2014
We performed a density functional theory (DFT) study of the monazite-type ceramics using DFT+U method, where the Hubbard U parameters are derived ab initio, with the main goal in testing the predictive power of this computational method for modeling of f-electron materials that are of interest in nuclear waste management. ...
Jiajue R R Department of Endocrinology, Key Laboratory of Endocrinology, Ministry of Health, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, No. 1 Shuaifuyuan, Wangfujing Street, Beijing, - - 2014
We found that type 2 diabetes mellitus (T2DM) was associated with increased fracture risks in non-obese postmenopausal Chinese women, and suppressed bone turnover might be the underlying mechanism. This is the first study evaluating and explaining the association of T2DM with osteoporotic fracture in Chinese population with such high homogeneity. ...
Joel D D School of Psychological Sciences, Tel Aviv University, Ramat-Aviv, Tel Aviv 69978, Israel; Sagol School of Neuroscience, Tel Aviv University, Ramat-Aviv, Tel Aviv 69978, - - 2014
In recent years there has been a growing recognition of the influence of sex on brain structure and function, and relatedly, on the susceptibility, prevalence and response to treatment of psychiatric disorders. Most theories and descriptions of the effects of sex on the brain are dominated by an analogy to ...
Tieges Zoë Z Edinburgh Delirium Research Group, Geriatric Medicine, Division of Health Sciences, School of Clinical Sciences, University of Edinburgh, Edinburgh, UK; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, - - 2014
Inattention is a core feature of delirium, and valid assessment of attention is central to diagnosis. Methods of measuring attention in delirium can be divided into two broad categories: (i) objective neuropsychological testing; and (ii) subjective grading of behaviour during interview and clinical examination. Here, we review and critically evaluate ...
Senn C C Department of Osteoporosis, Inselspital, Berne University Hospital and University of Berne, CH-3010, Berne, - - 2014
Treatment effects over 2 years of teriparatide vs. ibandronate in postmenopausal women with osteoporosis were compared using lumbar spine bone mineral density (BMD) and trabecular bone score (TBS). Teriparatide induced larger increases in BMD and TBS compared to ibandronate, suggesting a more pronounced effect on bone microarchitecture of the bone anabolic ...
Tao Lin L Department of Food and Nutrition, College of Health Science, Korea University, Seoul 136-703, - - 2014
Aspergillus oryzae is generally recognized as safe, but it is closely related to A. flavus in morphology and genetic characteristics. In this study, we tested aflatoxigenicity and genetic analysis of 9 commercial A. oryzae strains which were used in Korean soybean fermented products. Cultural and HPLC analysis showed that none ...
Kim Byung-Hyuk BH 125 Gwahak-ro, Yuseong-gu, - - 2014
This study evaluates the growth and nutrient removal ability of indigenous algal consortium on real untreated municipal wastewater in a high rate algal pond (HRAP). HRAP was operated semi-continuously under different hydraulic retention times (HRT: 2, 4, 6, and 8 days). The average removal efficiencies of chemical oxygen demand, total ...
Guo Hongwei H School of Biotechnology and Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu, 214122, - - 2014
Yarrowia lipolytica WSH-Z06 harbours a promising capability to oversynthesize α-ketoglutarate (α-KG). Its wide utilization is hampered by the formation of high concentrations of pyruvate. In this study, a metabolic strategy for the overexpression of the α and β subunits of pyruvate dehydrogenase E1, E2 and E3 components was designed to ...
Xiao Zhizhuang Z Aquatic and Crop Resource Development, National Research Council Canada, Montreal, Quebec, Canada, H4P - - 2014
The only available genome sequence for Rhizopus oryzae strain 99-880 was annotated to not encode any β-1,4-endoxylanase encoding genes of the glycoside hydrolase (GH) family 10 or 11. Here, we report the identification and cloning of two such members in R. oryzae strain NRRL 29086. Strain 29086 was one of ...
Bastakoti Bishnu Prasad BP World Premier International (WPI) Research Center for Materials Nanoarchitectonics, National Institute for Materials Science (NIMS), 1-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan. - - 2014
Here we report a direct synthesis of a mesoporous TiO2-RuO2 composite. Titanium tetraisopropoxide (TTIP) and RuCl3 are used as inorganic precursors for TiO2 and RuO2, respectively. Evaporation-induced assembly of spherical micelles made of an asymmetric poly(styrene-b-2-vinyl pyridine-b-ethylene oxide) triblock copolymer enables the fabrication of a mesoporous TiO2-RuO2 composite with a ...
Huang Yijuan Y Department of Radiation Medicine, Faculty of Naval Medicine, Second Military Medical University, Shanghai, - - 2014
Radiation-induced lung injury (RILI) is a potentially fatal and dose-limiting complication of thoracic radiotherapy. This study was to investigate the protective effects of grape seed pro-anthocyanidins (GSPs), an efficient antioxidant and anti-carcinogenic agent, on RILI. In our study, it was demonstrated that acute and late RILI was ameliorated after GSPs ...
Klingbeil E C EC Division of Allergy and Immunology, Stanford University School of Medicine, 300 Pasteur Drive, Rm. S-303, Stanford, CA, 94305-5107, USA, - - 2014
Environmental determinants including aerosolized pollutants such as polycyclic aromatic hydrocarbons (PAHs) and tobacco smoke have been associated with exacerbation and increased incidence of asthma. The influence of aerosolized pollutants on the development of immune dysfunction in asthmatics has been suggested to be mediated through epigenetic remodeling. Genome accessibility and transcription ...
Skou Anne-Sofie AS Department of Paediatrics, Aarhus University Hospital Skejby, Aarhus, - - 2014
We investigated the spectrum, frequency, and risk factors for renal, gastrointestinal, and hepatic late adverse effects in survivors of childhood acute myeloid leukemia (AML) without relapse treated with chemotherapy alone according to three consecutive AML trials by the Nordic Society of Pediatric Hematology and Oncology (NOPHO). A population-based cohort of ...
Das Chayanika C Polymer Science and Engineering Division, CSIR-National Chemical Laboratory, Dr Homi Bhabha Road, Pune 411008, India. - - 2014
Nanotubes with variable hydrophobic interiors were prepared by disassembling anionic micelles in the inner walls of positive charge bearing conjugated polymer nanotubes.
Sahni Shivani S Assistant Scientist II, Institute for Aging Research, Hebrew SeniorLife, Instructor, Beth Israel Deaconess Medical Center, Harvard Medical - - 2014
Dairy foods are rich in bone beneficial nutrients, yet the role of dairy foods in hip fracture prevention remains controversial. To evaluate the association of milk, yogurt, cheese, cream and milk + yogurt intakes with incident hip fracture in the Framingham Original Cohort. 830 men and women from the Framingham Original Cohort, ...
Abo-Salem Osama M OM Department of Laboratory Sciences and Clinical Technology, College of Applied Medical Sciences, Taif University, Taif, Saudi Arabia; Department of Pharmacology and Toxicology, Faculty of Pharmacy (Boys), Al-Azhar University, Nasr-City, Cairo, Egypt. - - 2014
Heart failure (HF) is one of diabetic complications. This work was designed to investigate the possible modulatory effect of curcumin against streptozotocin-induced diabetes and consequently HF in rats. Rats were divided into control, vehicle-treated, curcumin-treated, diabetic-untreated, diabetic curcumin-treated, and diabetic glibenclamide-treated groups. Animal treatment was started 5 days after induction ...
McClements David Julian DJ Biopolymers and Colloids Laboratory, Department of Food Science, University of Massachusetts Amherst, Amherst, MA 01003, USA. mcclements@foodsci.umass.edu - - 2014
The oral bioavailability of many lipophilic bioactive agents (pharmaceuticals and nutraceuticals) is limited due to various physicochemical and physiological processes: poor release from food or drug matrices; low solubility in gastrointestinal fluids; metabolism or chemical transformation within the gastrointestinal tract; low epithelium cell permeability. The bioavailability of these agents can ...
Sutoh Yoichi Y Department of Pathology, Hokkaido University Graduate School of Medicine, North 15 West 7, Sapporo, 060-8638, - - 2014
Unlike jawed vertebrates that use T cell and B cell receptors for antigen recognition, jawless vertebrates represented by lampreys and hagfish use variable lymphocyte receptors (VLR) as antigen receptors. VLRs generate high levels of diversity by assembling variable leucine-rich repeat (LRR) modules. Of the three VLRs thus far identified, VLRB ...
Spafford C C Sheffield Nordic Walking Research, Steps Physiotherapy and Circulation - - 2014
This was a randomized clinical trial to determine whether Nordic pole walking (NPW) is more effective in improving walking distance than a standard home exercise programme (HEP) in patients with intermittent claudication. Fifty-two patients with stable claudication were allocated randomly to a standard HEP or NPW group, and asked to ...
Babiarczyk Beata B Department of Nursing, Faculty of Health Sciences, University of Bielsko-Biała, Bielsko-Biala, - - 2014
Self-reported body mass index (BMI) is commonly used to assess nutritional status. The aim of the study was to assess the accuracy of self-reported and measured data obtained from the inpatient population. A total of 296 individuals admitted to five hospital wards were included in the study. Patients provided details ...
Zarin Taraneh T Department of Cell & Systems Biology, University of Toronto, 25 Willcocks Street, Toronto, ON, M5S 3B2, - - 2014
Enabled by comparative genomics, yeasts have increasingly developed into a powerful model system for molecular evolution. Here we survey several areas where yeast studies have made important contributions including regulatory evolution, gene duplication and divergence, evolution of gene order, and evolution of complexity. In each area we highlight key studies ...
Li Jun J National Institute of Advanced Industrial Science and Technology (AIST), Ikeda, Osaka, Japan. - - 2014
Ultrafine AuCo alloy nanoparticles were successfully encapsulated in the pores of MIL-101 by using the double solvents method combined with the overwhelming reduction approach, which exert excellent catalytic activity for hydrolytic dehydrogenation of ammonia borane.
Govani S M SM Division of Gastroenterology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, - - 2014
The prevalence of heterotopic gastric mucosa of the upper esophagus (inlet patch) has a wide range depending on the method and detail of examination. The inlet patch is believed to be a congenital malformation that rarely leads to symptoms. We aimed to quantify the prevalence of the inlet patch in ...
Sugiyama Munehiro M Department of Radiology, National Cerebral and Cardiovascular Center, 5-7-1 Fujishiro-dai, Suita, Osaka, 565-8565, Japan, - - 2014
To assess the usefulness of cone-beam CT (CBCT) during pulmonary angiography for the evaluation of organized thrombus at segmental or subsegmental arteries in patients with chronic thromboembolic pulmonary hypertension (CTEPH). The segmental and/or subsegmental pulmonary arteries of 13 patients with CTEPH were evaluated by CBCT. We classified representative forms of ...
Smith Malcolm A MA National Cancer Institute, Bethesda, - - 2014
Agents targeting the vascular endothelial growth factor (VEGF) pathway have been studied in adults with cancer for nearly two decades. It is important to assess the lessons learned from this adult experience and to see how these lessons can help inform pediatric development of agents in this class. The benefit ...
Liu Ya-Ming YM Department of Hepatology, First Hospital of Jilin University, Changchun, Jilin, - - 2014
Human beta2-glycoprotein I (beta2-GPI) binds to recombinant hepatitis B surface antigen (rHBsAg) and can bind specifically to annexin II, which is located on the cell membrane of human hepatoma SMMC-7721 cells. Viral envelope proteins are essential for mediating cellular entry. The aim of this study was to investigate the role ...
Inness Emma K EK Radiation Oncology, Princess Alexandra Hospital, Woolloongabba, Brisbane, QLD, 4102, Australia, - - 2014
A computed tomography number to relative electron density (CT-RED) calibration is performed when commissioning a radiotherapy CT scanner by imaging a calibration phantom with inserts of specified RED and recording the CT number displayed. In this work, CT-RED calibrations were generated using several commercially available phantoms to observe the effect ...
Auer Michael M neccton ltd, Office 404 Albany House, 324 Regent Street, London, W1B 3HH, UK, - - 2014
In this paper, we provide a brief response to Braverman et al. (J Gambl Stud. doi: 10.1007/s10899-013-9428-z , 2013b) critique of our 'Theoretical Loss' metric as a measure of monetary gambling intensity (Auer and Griffiths in J Gambl Stud. doi: 10.1007/s10899-013-9376-7 , 2013a; Auer et al. in Gaming Law Rev ...
Zhang Qu - - 2014
With its plumage color dimorphism and unique history in North America, including a recent population expansion and an epizootic of Mycoplasma gallisepticum (MG), the house finch (Haemorhous mexicanus) is a model species for studying sexual selection, plumage coloration and host-parasite interactions. As part of our ongoing efforts to make available ...
Saghafi Massoud M Rheumatic Diseases Research Center, Ghaem Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, - - 2014
Rheumatoid arthritis (RA) is a chronic inflammatory disease of the joints that has a strong correlation with HLA-DRB1. Family history is considered a known risk factor for RA. The aims of this study were to compare the frequency of HLA-DRB1 alleles between patients with sporadic and familial RA and also ...
Jansen Tim L TL Department of Rheumatology, Radboud University Medical Centre, Geert Grooteplein Noord 8, 6525 GA, Nijmegen, The Netherlands, - - 2014
Monosodium urate (MSU) monohydrate crystals synergize with various toll-like receptor (TLR) ligands to induce interleukin-(IL)-1β production. Data are shown from a young male with mitochondriopathy in Kearns-Sayre syndrome (KSS) who developed gout and underwent urate-lowering therapy (ULT) versus a group of common gout patients. Peripheral blood mononuclear cells (PBMCs) are ...
Retegan Marius M Max Planck Institute for Chemical Energy Conversion, Stiftstr. 34-38, 45470 Mülheim an der Ruhr, Germany. - - 2014
The EPR "split signals" represent key intermediates of the S-state cycle where the redox active D1-Tyr161 (YZ) has been oxidized by the reaction center of the photosystem II enzyme to its tyrosyl radical form, but the successive oxidation of the Mn4CaO5 cluster has not yet occurred (SiYZ˙). Here we focus ...
Lince Sabrina L SL Department of Obstetrics and Gynecology (791), Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands, - - 2014
The rs1800255, COL3A1 2209 G>A polymorphism in the alpha 1 chain of collagen type III has been associated with an increased risk of pelvic organ prolapse (POP). In one of our previous studies however, polymerase chain reaction-based restriction fragment length polymorphism (PCR-RFLP) misdiagnosed rs1800255, COL3A1 2209 G>A in 6 % of cases. The ...
Röder Gregory G Laboratory of Fundamental and Applied Research in Chemical Ecology (FARCE), Institute of Biology, University of Neuchâtel, Rue Emile-Argand 11, 2000, Neuchâtel, - - 2014
The great spotted cuckoo (Clamator glandarius) is an important brood parasite of carrion crows (Corvus corone corone) in northern Spain. We recently found that, unlike what is commonly known for cuckoo-host interactions, the great spotted cuckoo has no negative impact on average crow fitness in this region. The explanation for ...
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