Search Results
Results 351 - 400 of 2994
< 3 4 5 6 7 8 9 10 11 12 13 >
Mofrad Farshid Babapour FB Faculty of Engineering, Science and Research Branch, Islamic Azad University (IAU), Tehran, 14515-775, Iran, - - 2014
Liver-shape analysis and quantification is still an open research subject. Quantitative assessment of the liver is of clinical importance in various procedures such as diagnosis, treatment planning, and monitoring. Liver-shape classification is of clinical importance for corresponding intra-subject and inter-subject studies. In this research, we propose a novel technique for ...
Wen Fengtong F School of Mathematical Sciences, University of Jinan, Jinan, 250022, China, - - 2014
Secure and efficient user mutual authentication is an essential task for integrated electronic patient record (EPR) information system. Recently, several authentication schemes have been proposed to meet this requirement. In a recent paper, Lee et al. proposed an efficient and secure password-based authentication scheme used smart cards for the integrated ...
Yang Peng P Institute for Health Informatics, Fourth Military Medical University, Xi'an, China, - - 2014
A key purpose of electronic medical records (EMR) introduced in medical institutions is to improve work efficiency. The average length of stay (LOS) is just an important indicator to evaluate work efficiency of medical care in hospitals. Recently, there have been reports about effects of EMR application on LOS in ...
Kristensen Vessela N VN 1] Department of Genetics, Institute for Cancer Research, Oslo University Hospital, The Norwegian Radium Hospital, Montebello, 0310 Oslo, Norway. [2] K.G. Jebsen Centre for Breast Cancer Research, Institute for Clinical Medicine, Faculty of Medicine, University of Oslo, 0313 Oslo, Norway. [3] Department of Clinical Molecular Oncology, Division of Medicine, Akershus University Hospital, 1478 Ahus, - - 2014
Combined analyses of molecular data, such as DNA copy-number alteration, mRNA and protein expression, point to biological functions and molecular pathways being deregulated in multiple cancers. Genomic, metabolomic and clinical data from various solid cancers and model systems are emerging and can be used to identify novel patient subgroups for ...
Zhang Xing-Mao XM Department of Gastrointestinal Surgery, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, 17 Panjiayuan Nanli, Chaoyang District, Beijing, 100021, - - 2014
This study was designed to explore the influence of intra-operative perforation on prognosis of low rectal cancer after APR and to investigate the risk factors of perforation. Perforation is not scarce during the procedure of abdominoperineal resection (APR). There is no consensus on perforation rate and related risk factor for ...
Cortez Diego D 1] Center for Integrative Genomics, University of Lausanne, 1015 Lausanne, Switzerland [2] Swiss Institute of Bioinformatics, 1015 Lausanne, - - 2014
Y chromosomes underlie sex determination in mammals, but their repeat-rich nature has hampered sequencing and associated evolutionary studies. Here we trace Y evolution across 15 representative mammals on the basis of high-throughput genome and transcriptome sequencing. We uncover three independent sex chromosome originations in mammals and birds (the outgroup). The ...
Barends R R 1] Department of Physics, University of California, Santa Barbara, California 93106, USA - - 2014
A quantum computer can solve hard problems, such as prime factoring, database searching and quantum simulation, at the cost of needing to protect fragile quantum states from error. Quantum error correction provides this protection by distributing a logical state among many physical quantum bits (qubits) by means of quantum entanglement. ...
Hasenclever Jörg J GEOMAR, Helmholtz Centre for Ocean Research Kiel, Wischhofstraße 1-3, 24148 Kiel, - - 2014
Hydrothermal flow at oceanic spreading centres accounts for about ten per cent of all heat flux in the oceans and controls the thermal structure of young oceanic plates. It also influences ocean and crustal chemistry, provides a basis for chemosynthetic ecosystems, and has formed massive sulphide ore deposits throughout Earth's ...
Lee Cheng-Chia CC Department of Neurological Surgery, University of Virginia Health System, Charlottesville, VA, - - 2014
To evaluate the effect of stereotactic radiosurgery (SRS) on intracranial metastases with diffusion-weighted imaging/apparent diffusion coefficient maps. A total of 107 patients with 144 metastases larger than 1 cm in diameter were retrospectively reviewed. We calculated the DWITumor/white matter ratios (DWIT/WM ratio) between the metastases and the normal, contralateral frontal white ...
Jamerson Deandra D University of Rochester Medical Center Heart Research Follow-up Program, Rochester, - - 2014
Whether gender differences exist in procedure-related adverse events following CRT-D implantation is unknown. We investigated the type and frequency of procedure-related adverse events among those enrolled in MADIT-CRT and identified clinical predictors for gender-specific events. We compared differences in the rate of procedure-related adverse events by gender (444 females and ...
Perotto Silvia S Department of Life Sciences and Systems Biology, University of Turin, Viale Mattioli 25, 10125, Turin, Italy, - - 2014
Orchid mycorrhiza has been often interpreted as an antagonistic relationship. Our data on mycorrhizal protocorms do not support this view as plant defence genes were not induced, whereas some nodulin-like genes were significantly up-regulated. Orchids fully depend on symbiotic interactions with specific soil fungi for seed germination and early development. ...
Makai Peter P Department of Geriatrics, Radboud University Medical Center, Renier Postlaan 4, 6500 HB, Nijmegen, The Netherlands, - - 2014
Economic evaluations likely undervalue the benefits of interventions in populations receiving both health and social services, such as frail elderly, by measuring only health-related quality of life. For this reason, alternative preference-based instruments have been developed for economic evaluations in the elderly, such as the ICECAP-O. The aim of this ...
Urquia Ml M St. Michael's Hospital, Toronto, ON, Canada; Institute for Clinical Evaluative Sciences, Toronto, ON, Canada; Dalla Lana School of Public Health, University of Toronto, Toronto, ON, - - 2014
To assess disparities in preeclampsia and eclampsia among immigrant women from various world regions giving birth in six industrialised countries. Cross-country comparative study of linked population-based databases. Provincial or regional obstetric delivery data from Australia, Canada, Spain and the USA and national data from Denmark and Sweden. All immigrant and ...
Braeckman Rene A RA Amarin Pharma Inc., 1430 Route 206, Suite 200, Bedminster, NJ, 07921, - - 2014
Icosapent ethyl (IPE) is a high-purity prescription form of eicosapentaenoic acid (EPA) ethyl ester approved to reduce triglyceride levels in patients with severe (≥5.65 mmol/L) hypertriglyceridemia. EPA, the active metabolite of IPE, is mainly metabolized via β-oxidation, and studies suggest that omega-3 fatty acids such as EPA may have antithrombotic effects. ...
Gaudio Francesco F Department of Emergency and Organ Transplantation (D.E.T.O.), Hematology Section, University of Bari Medical School, Bari, Italy, - - 2014
The aim of this study was to evaluate the role of computed tomography (CT)-guided core needle biopsy (CNB) performed by modified coaxial technique as an alternative tool to surgical biopsy in patients with refractory or recurrent lymphomas. Between May 2005 and May 2012, 57 CT-guided CNB of deep lesions were ...
Neumann Bettina B Fraunhofer Institute for Biomedical Engineering IBMT, Am Mühlenberg 13, 14476, Potsdam, Golm, - - 2014
Binding of heme to the amyloid peptides Aβ40/42 is thought to be an initial step in the development of symptoms in the early stages of Alzheimer's disease by enhancing the intrinsic peroxidatic activity of heme. We found considerably higher acceleration of the reaction for the physiologically relevant neurotransmitters dopamine and ...
Würtenberger Irene I Department of Pharmaceutical Chemistry, Institute of Pharmacy, Center for Molecular Biosciences Innsbruck, Center for Chemistry and Biomedicine (CCB), University of Innsbruck, Innrain 80-82, 6020, Innsbruck, - - 2014
We report here the development, optimization, and evaluation of a highly sensitive method for the determination of fluorine in biological matrices employing highresolution continuum source molecular absorption spectrometry (HR-CS MAS), suitable for pharmacological testing of fluorine-containing drug candidates. For this purpose, the most important parameters were studied in detail and ...
Esakoff Tania F TF Cedars Sinai Medical Center, Department of Obstetrics and Gynecology, Los Angeles, - - 2014
Abstract Introduction: Velamentous cord insertion (VCI) can be identified on prenatal ultrasound with an incidence of around 1%. We set out to examine the association between VCI and perinatal outcomes. Methods: This was a retrospective cohort study of 482,812 pregnancies using the California vital statistics birth cohort dataset linked with ...
Ali I H A IH Centre for Experimental Medicine, Queen's University Belfast, Belfast BT12 6BA, Northern Ireland, - - 2014
Bone morphogenetic proteins (BMPs) are members of the TGF-β superfamily of secreted cysteine knot proteins which includes TGF-β1, nodal, activins and inhibins. BMPs were first discovered by Urist in the 1960s when he showed that implantation of demineralised bone into intramuscular tissue of rabbits induced bone and cartilage formation. Since ...
Uenishi Takahiro T Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, - - 2014
Hepatitis C virus (HCV) infection plays an important role in the development of not only hepatocellular carcinoma (HCC) but also intrahepatic cholangiocarcinoma (ICC). The aim of this study was to identify the specific characteristics of HCV-related ICC. Of 90 patients who underwent curative resection for mass-forming ICC, 33 patients had ...
Kitamura Atsuko A Department of Pediatrics, Nagasaki University Graduate School of Biomedical Science, Nagasaki, Japan; Department of Molecular Microbiology and Immunology , Nagasaki University Graduate School of Biomedical Science, Nagasaki, - - 2014
Despite the fact that functional lower urinary tract symptoms are common among people with Down syndrome (DS), their voiding function has not been studied precisely. Our goal was to assess the lower urinary tract functions in DS. Fifty-five DS children aged 5 to 15 years old and 35 age-matched control ...
Gautam Neetu N Department of Pediatrics, S.N. Medical College, Agra, - - 2014
To assess the immuno-clinical response of micronutrients supplementation in human immunodeficiency virus (HIV) infected children (both on and without antiretroviral therapy) and to assess the role of probiotics in improvement of CD4 counts in HIV infected children not on antiretroviral therapy. This was an open labeled randomized control study, conducted ...
Morales-Rivera Amarilys A Department of Pharmacology and Toxicology, University of Puerto Rico-Medical Sciences Campus, P.O. Box 565067, San Juan, PR, 00936, USA, - - 2014
Oxytocin (OT) is a neuropeptide previously related to reward, learning, memory, and stress, events associated with cocaine addiction. OT has shown anxiolytic properties in different animal models of anxiety. Moreover, previous data have demonstrated an increase in mRNA OT levels within the nucleus accumbens (NAc) following acute and chronic cocaine ...
Chibber Rachana R Department of Obstetrics and Gynecology, Faculty of Medicine, Kuwait University - - 2014
Abstract Objective: To compare the outcome of induced and spontaneous labor in grand multiparous women with one previous lower segment cesarean section, so that the safety of labor induction could be assessed. Methods: In 102 women (study group) labor was induced and the outcome was compared with 280 women (control ...
Kar Mega M Australian Centre for Electromaterials Science (ACES), School of Chemistry, Monash University, Clayton 3800, Victoria, Australia. - - 2014
The coordination of zinc ions by tetraglyme has been investigated here to support the development of novel electrolytes for rechargeable zinc batteries. Zn(2+) reduction is electrochemically reversible from tetraglyme. The spectroscopic data, molar conductivity and thermal behavior as a function of zinc composition, between mole ratios [80 : 20] and [50 : 50] [tetraglyme : zinc ...
Bauer R R Neurosurgery, Landeskrankenhaus Feldkirch, Feldkirch, Austria, - - 2014
Epileptic seizures represent a common signal of intracranial tumors, frequently the presenting symptom and the main factor influencing quality of life. Treatment of tumors concentrates on survival; antiepileptic drug (AED) treatment frequently is prescribed in a stereotyped way. A differentiated approach according to epileptic syndromes can improve seizure control and ...
Lee Christopher M CM Department of Chemical Engineering and Materials Research Institute, The Pennsylvania State University, University Park, PA 16802, USA. - - 2014
This study reports that the noncentrosymmetry and phase synchronization requirements of the sum frequency generation (SFG) process can be used to distinguish the three-dimensional organization of crystalline cellulose distributed in amorphous matrices. Crystalline cellulose is produced as microfibrils with a few nanometer diameters by plants, tunicates, and bacteria. Crystalline cellulose ...
Shailasree S S Institution of Excellence, Vijnana Bhavana, University of Mysore, Mysore, 570006, India, - - 2014
p-Coumaric acid (p-CA), an ubiquitous plant phenolic acid, has been proven to render protection against pathological conditions. In the present study, p-CA was evaluated for its capacity to induce cytotoxic effect to neuroblastoma N2a cells and we report here the possible mechanism of its action. p-CA at a concentration of ...
Huang Wen W Department of Electrical and Computer Engineering, National University of Singapore, Singapore 117576, Republic of Singapore. - - 2014
Molybdenum disulfide (MoS2) and tungsten diselenide (WSe2) are prototypical layered two-dimensional transition metal dichalcogenide materials, with each layer consisting of three atomic planes. We refer to each layer as a trilayer (TL). We study the thermoelectric properties of 1-4TL MoS2 and WSe2 using a ballistic transport approach based on the ...
Gray D M DM Division of Gastroenterology, Washington University School of Medicine, St. Louis, Missouri, - - 2014
Cameron lesions, as defined by erosions and ulcerations at the diaphragmatic hiatus, are found in the setting of gastrointestinal (GI) bleeding in patients with a hiatus hernia (HH). The study aim was to determine the epidemiology and clinical manifestations of Cameron lesions. We performed a retrospective cohort study evaluating consecutive ...
Jung Youngsin Y Department of Neurology (Behavioral Neurology), Mayo Clinic, Rochester, MN, - - 2014
Widespread deposition of TAR DNA-binding protein of 43 kDa (TDP-43), a major protein inclusion commonly found in frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS) can also be seen in a subset of cases with Alzheimer's disease (AD). Some of these AD cases have TDP-43 immunoreactivity in basal ganglia (BG) ...
Lehn Alexander C AC Department of Neurology, Princess Alexandra Hospital, Brisbane, QLD, 4102, Australia, - - 2014
The idiomuscular response to direct percussion is rarely tested nowadays because of its uncertain mechanism and significance. While performing neurological examination, we observed a brisk ankle dorsiflexion response on direct muscle percussion of m. tibialis anterior in patients with acute inflammatory demyelinating polyradiculoneuropathy (AIDP). In contrast, in patients with upper ...
Namikawa Tsutomu T Department of Surgery, Kochi Medical School, Kohasu, Oko-cho, Nankoku, Kochi, 783-8505, Japan, - - 2014
Pylorus-preserving gastrectomy (PPG) is sometimes performed as a function-preserving surgery for the treatment of early gastric cancer. The aim of this study was to use an integrated assessment scale for postgastrectomy syndrome to determine the appropriate indicators and optimal methods for PPG. The Postgastrectomy Syndrome Assessment Study (PGSAS) is a ...
Kanno Sanae S Department of Legal Medicine, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-ku, Kawasaki, 216-8511, Japan, - - 2014
Long fibers, such as asbestos and carbon nanotubes (CNTs), are more potent activators of inflammatory and genotoxicity than short or tangled fibers. Fibrous particles trigger interleukin (IL)-1β secretion and cause inflammatory diseases through NLRP3 inflammasomes in phagocytotic cells. However, the mechanism involved in fibrous particle-induced inflammation has not been well ...
Guaraldi Giovanni G Metabolic Clinic, University of Modena and Reggio Emilia, Modena, - - 2014
The introduction of HAART has represented a major advance in the care of people with HIV. By markedly increasing life expectancy, HAART has significantly changed the pattern of HIV infection in developed countries, the "graying" of the HIV-infected population being a powerful testament to its success. However, this has presented ...
Wang Wei W Department of Medical Ultrasonics, Institute of Diagnostic and Interventional Ultrasound, The First Affiliated Hospital of Sun Yat-Sen University, No. 58 Zhongshan Road 2, Guangzhou, 510080, People's Republic of - - 2014
To assess the feasibility and efficiency of a perspective view technology (Fly Thru) for the detection of portal vein tumor thrombus (PVTT) in hepatocellular carcinoma (HCC) patients. Fly Thru was performed in 79 HCC patients. The images were reviewed off-site for evaluation of the imaging quality and diagnosis. Pathology and/or ...
Orkin Chloe C Barts Health NHS Trust, London, - - 2014
Vitamin D deficiency in HIV infection has attracted much interest. The best known clinical outcomes of vitamin D deficiency are rickets (children) and osteomalacia (adults). Several non-skeletal disorders have also been linked to suboptimal vitamin D levels in the general population. The prevalence of vitamin D deficiency varies widely (6-100%) ...
Weber Nicholas K NK Division of Gastroenterology & Hepatology, Mayo Clinic College of Medicine, 200 First Street, SW, Rochester, MN, 55905, - - 2014
Small bowel adenocarcinoma is uncommon in patients with Crohn's disease but has an extremely poor prognosis. There is a paucity of data on the clinical characteristics and radiologic features of this entity. We sought to update our institutional experience with small bowel adenocarcinoma occurring in the setting of Crohn's disease ...
Zhang Ge G Department of Radiology, West China Hospital, Sichuan University, 37 GuoXue Street, Chengdu, 610041, Sichuan, - - 2014
To clarify features of lymph nodes associated with leukemia purposing to offer help for imaging diagnosis and differential diagnosis of leukemia. We retrospectively analyzed 47 patients with clinically proven leukemia involving the abdominal and pelvic lymph nodes. Of these 47 patients, 10 had acute myeloid leukemia, 9 had acute lymphocytic ...
Baglio V V Istituto di Tecnologie Avanzate per l'Energia "Nicola Giordano" Consiglio Nazionale delle Ricerche, Salita S. Lucia sopra Contesse, 5 - 98126 Messina, Italy. - - 2014
A multifunctional catalyst may represent a valid route to enhance methanol electro-oxidation. Ternary catalysts based on Pt modified with both Ru and Ir oxides show better performance for methanol electro-oxidation than bi-metallic Pt-Ru catalysts.
Stöllberger Claudia C Krankenanstalt Rudolfstiftung, Wien, - - 2014
Myofibrillar myopathy is characterized by non-hyaline and hyaline lesions due to mutations in nuclear genes encoding for extra-myofibrillar or myofibrillar proteins. Cardiac involvement in myofibrillar myopathy may be phenotypically expressed as dilated, hypertrophic or restrictive cardiomyopathy. Radiofrequency ablation of atrial fibrillation and flutter has so far not been reported in ...
KarakuĊŸ Esra E Pathology Department, Ankara Children's Hematology and Oncology Research and Training Hospital, Ankara, - - 2014
In this study, we probed whether chronic infections of skin such as pilonidal sinus could be a potential site of Epstein-Barr virus (EBV) replication. Pilonidal sinus is associated with a high recurrence rate. Therefore, we decided to determine the role of EBV's presence to explain whether it is correlated with ...
Kristin Julia J University Hospital Duesseldorf Head and Neck Surgery, Moorenstrasse 5, 40225, Düsseldorf, Germany, - - 2014
Endoscope holders are utilized by a variety of surgeons but are not commonplace in head and neck surgery. The SOLOASSIST active camera holder, which is currently used for abdominal surgery, will soon be adapted for head and neck surgery in collaboration with AKTORmed GmbH SOLO SURGERY (Barbing, Germany). In our ...
Quintela Telma T CICS-UBI-Health Sciences Research Centre, University of Beira Interior, Av. Infante D. Henrique, Covilhã, 6200-506, Portugal, - - 2014
Evidence from the literature suggests that testosterone (T) plays an important role in the neural structure, physiology, and function of the hippocampus (HP). However, many of the genes involved and underlying mechanisms remain to be elucidated. To shed light on this issue, we explored the transcriptome of HP in orchidectomized ...
Ojala Frida F Department of Chemical Engineering, Lund University, P.O. Box 124, 221 00 Lund, - - 2014
Interest in monoclonal antibody aggregation is increasing as aggregates of biopharma-ceuticals can cause an immunogenic response when injected into the body. In this work a stoichiometric reaction model from concentration-time data is developed to predict the dimer ratio in stored antibody solutions over time. IgG1 was incubated at pH from ...
Fons Pierre P Sanofi Recherche and Développement, Toulouse, - - 2014
Tumor angiogenesis is also accompanied by vasculogenesis which is involved in the differentiation and mobilization of human bone marrow cells. In order to further characterize the role of vasculogenesis in the tumor growth process, the effects of FGF2 on the differentiation of human bone marrow AC133(+) cells (BM-AC133(+) ) into ...
Fernández Roberto R Department of Physical Chemistry, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Barrio Sarriena s/n, 48940, Leioa, - - 2014
Human tumor xenografts in immunodeficient mice are a very popular model to study the development of cancer and to test new drug candidates. Among the parameters analyzed are the variations in the lipid composition, as they are good indicators of changes in the cellular metabolism. Here, we present a study ...
Valverde-Tercedor C C Departamento de Microbiología, Facultad de Ciencias, Universidad de Granada, Campus de Fuentenueva s/n, 18071, Granada, - - 2014
Magnetotactic bacteria are a diverse group of prokaryotes that biomineralize intracellular magnetosomes, composed of magnetic (Fe3O4) crystals each enveloped by a lipid bilayer membrane that contains proteins not found in other parts of the cell. Although partial roles of some of these magnetosome proteins have been determined, the roles of ...
Knight Danica K DK Institute of Behavioral Research, Texas Christian University (TCU), Box 298740, Fort Worth, TX, 76129, USA, - - 2014
Although adolescents demonstrate capacity for rational decision making, their tendency to be impulsive, place emphasis on peers, and ignore potential consequences of their actions often translates into higher risk-taking including drug use, illegal activity, and physical harm. Problems with judgment and decision making contribute to risky behavior and are core ...
Cook Daniel - - 2014
Swainsonine, an indolizidine alkaloid with significant physiological activity, is an α-mannosidase and mannosidase II inhibitor that alters glycoprotein processing and causes lysosomal storage disease. Swainsonine is present in a number of plant species worldwide and causes severe toxicosis in livestock grazing these plants. Consumption of these plants by grazing animals ...
< 3 4 5 6 7 8 9 10 11 12 13 >