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Kanistras Ioannis I Immunology Laboratory, Department of Biochemistry, Hellenic Pasteur Institute, Athens, - - 2014
Experimental autoimmune thyroiditis (EAT) is commonly induced by thyroglobulin (Tg) or Tg peptides in mice genetically susceptible to thyroiditis. In the present study, we investigated the immunogenic and pathogenic potential of a novel 20mer human Tg peptide, p2208 (amino acids 2208-2227), in mouse strains classified as low (LR) or high ...
Link Mark S MS The Cardiac Arrhythmia Center, Tufts Medical Center, 800 Washington Avenue, Boston, MA, 02111, USA, - - 2014
Commotio cordis is increasing described and it is now clear that this phenomenon is an important cause of sudden cardiac death on the playing field. Victims are predominantly young, male, and struck in the left chest with a ball. An animal model has been developed and utilized to explore the ...
Narouze Samer S Summa Western Reserve Hospital, Cuyahoga Falls, OH, USA, - - 2014
Cervical sympathetic and stellate ganglion blocks (SGB) provide a valuable diagnostic and therapeutic benefit to sympathetically maintained pain syndromes in the head, neck, and upper extremity. With the ongoing efforts to improve the safety of the procedure, the techniques for SGB have evolved over time, from the use of the ...
Charleston Larry L 4th Department of Neurology, Headache and Neuropathic Pain Clinic, University of Michigan, 1914 Taubman Center, 1500 E. Medical Center Dr. SPC 5316, Ann Arbor, MI, 48109-5316, USA, - - 2014
The interplay between head pain caused by sinus disease and primary headaches is complex. Classification of secondary headaches, attributed to disorders of the nose or paranasal sinuses has been recently updated. New treatments including office- based procedures are emerging for patients with chronic sinusitis. This paper briefly reviews sinus disease ...
Rome Benjamin N BN Program On Regulation, Therapeutics, And Law (PORTAL), Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, 1620 Tremont St., Suite 3030, Boston, MA, 02120, USA, - - 2014
Since 1976, the US Food and Drug Administration (FDA) has used the premarket approval (PMA) process to approve high-risk medical devices, including implantable cardioverter defibrillators (ICDs), coronary stents, and artificial heart valves. The PMA process is widely viewed as a rigorous evaluation of device safety and effectiveness, though recent recalls-most ...
Jia Guanghong G Division of Endocrinology and Metabolism, Department of Medicine, University of Missouri School of Medicine, Columbia, MO, - - 2014
Population level data support that consumption of fructose and fructose-based sweeteners has dramatically increased and suggest that high dietary intake of fructose is an important factor in the development of the cardiorenal metabolic syndrome (CRS). The CRS is a constellation of cardiac, kidney and metabolic disorders including insulin resistance, obesity, ...
Maciejewski Dominique F DF Department of Developmental Psychology and EMGO Institute for Health and Care Research, VU University, Amsterdam, the - - 2014
Nonsuicidal self-injury (NSSI) and suicidal self-injury are very harmful behaviors and are associated with several psychiatric disorders. In the recently developed fifth edition of the DSM, NSSI and suicidal behavior disorder are for the first time introduced as conditions in their own right instead of symptoms of other psychiatric disorders. ...
Etelvino Gisele Maia GM National Institute of Science and Technology in Nanobiopharmaceutics, Department of Physiology and Biophysics, Federal University of Minas Gerais, Av. Antonio Carlos, 6627 - ICB - UFMG, 31270-901, Belo Horizonte, MG, - - 2014
The renin-angiotensin system is an important component of the central and humoral mechanisms of blood pressure and hydro-electrolytic balance control. Angiotensin II is a key player of this system. Twenty-five years ago the first manuscripts describing the formation and actions of another peptide of the RAS, angiotensin-(1-7), were published. Since ...
Diestelmeier B W - - 2014
For systematic laboratory studies of bone fractures in general and intra-articular fractures in particular, it is often necessary to control for injury severity. Quantitatively, a parameter of primary interest in that regard is the energy absorbed during the injury event. For this purpose, a novel technique has been developed to ...
Currie Gillian L GL Department of Clinical Neurosciences, Chancellor's Building, University of Edinburgh, Edinburgh, UK, - - 2014
Cancer pain is not a single entity but a complex pain state involving different pain syndromes, with inflammatory, neuropathic, compressive, and ischaemic mechanisms. Current therapeutic regimens are based largely on opioids, although opioid treatment can lead to many side effects. Studies using animal models of cancer pain are aimed at ...
Spears Roderick C RC Center for Headache Management, Crozer Chester Medical Center, 1 Medical Center Blvd., Upland, PA, 19013, USA, - - 2014
Low cerebrospinal fluid (CSF) pressure results in neurologic deficits, of which the most common manifestation is headache. Typically, the headache is postural - and specifically, orthostatic - in presentation. There are three hypotheses to explain the occurrence of headache associated with low CSF fluid. The first is traction on pain-sensitive ...
Davies Andrew N AN Consultant in Palliative Medicine, Royal Surrey County Hospital, Egerton Road,, Guildford, Surrey, GU2 7XX, UK, - - 2014
Breakthrough pain is a distinct pain state that is common in patients with cancer pain and which is associated with significant morbidity in this group of patients. The aim of this article is to highlight important journal articles relating to breakthrough pain that have been published within the last year, ...
Freeman Jennifer J Alpert Medical School of Brown University; Bradley-Hasbro Children's Research Center, Providence, Rhode - - 2014
Cognitive behavior therapy (CBT) has been established as efficacious for obsessive-compulsive disorder (OCD) among older children and adolescents, yet its effect on young children has not been evaluated sufficiently. To examine the relative efficacy of family-based CBT (FB-CBT) involving exposure plus response prevention vs an FB relaxation treatment (FB-RT) control ...
Montezano Augusto C AC Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, - - 2014
Vascular injury, characterized by endothelial dysfunction, structural remodelling, inflammation and fibrosis, plays an important role in cardiovascular diseases. Cellular processes underlying this include altered vascular smooth muscle cell (VSMC) growth/apoptosis, fibrosis, increased contractility and vascular calcification. Associated with these events is VSMC differentiation and phenotypic switching from a contractile to ...
Hocker Sara S Department of Neurology, Mayo Clinic, 200 1st St SW, Rochester, MN, 55902, USA, - - 2014
Status epilepticus is a medical emergency with a high mortality. Early recognition and initiation of treatment leads to a better response and may improve outcomes. Refractory status epilepticus is defined as recurrent seizure activity despite two appropriately selected and dosed antiepileptic drugs including a benzodiazepine. The term "super-refractory status epilepticus" ...
Ghaffari Bijan D BD Department of Neurology, University of Colorado School of Medicine, Academic Office 1, Mail Stop B-185 12631 East 17th Avenue, Aurora, CO, 80045, USA, - - 2014
At least 40 % of patients with Parkinson's disease (PD) use one or more forms of alternative therapy (AT) to complement standard treatments. This article reviews the commonest forms of AT for PD, including acupuncture, tai chi, yoga, mindfulness, massage, herbal medicine, and cannabis. We discuss the current evidence for the ...
Kacperski Joanne J Division of Neurology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave - MLC 2015, Cincinnati, OH, 45229-3039, USA, - - 2014
While headaches in children are quite common, the study and characterization of headache disorders in the pediatric age group has historically been limited. In the absence of controlled studies on prophylactic treatment of the primary headache disorders in this age group, the diagnosis of childhood migraine rests on criteria similar ...
Nováková Lucie L Department of Analytical Chemistry, Faculty of Pharmacy, Charles University, Heyrovského 1203, Hradec Králové 500 05, Czech Republic. Electronic address: - - 2014
This tutorial provides an overview of the possibilities, limitations and analytical conditions of modern analytical supercritical fluid chromatography (SFC) using columns packed with sub-2μm particles. In particular, it gives a detailed overview of commercially available modern SFC instrumentation and the detectors that can be employed (UV, MS, ELSD, FID, etc.). ...
Di Natale Corrado C Department of Electronic Engineering, University of Rome Tor Vergata, via del Politecnico 1, Roma 00133, Italy. Electronic address: - - 2014
The analysis of volatile compounds is an efficient method to appraise information about the chemical composition of liquids and solids. This principle is applied to several practical applications, such as food analysis where many important features (e.g. freshness) can be directly inferred from the analysis of volatile compounds. The same ...
Jacobson Joy J Joy - - 2014
A heroin epidemic spurs new laws as nurses work to prevent deaths.
Jobe Laura L LL Author Affiliation: RN III, Special Staffing Team, Arkansas Children's Hospital, Little - - 2014
The purpose of this study was to understand if differences in dimensions of work ethic exist among 3 generations of nurses working in an inpatient setting at an acute care facility. Generational differences are linked with increased turnover, with work ethic frequently cited as an important difference. The quantitative, quasi-experimental ...
Pasanen Mark E ME Department of Medicine, University of Vermont College of Medicine, 1234 Spear Street, 111 Colchester Avenue, South Burlington, VT 05403, USA. Electronic address: - - 2014
Symptoms related to colonic function are common and frequently related to functional issues. Possible presentations include constipation and either acute or chronic diarrhea. Because acute diarrhea is most commonly infectious, issues typically center on the role of stool testing and antibiotic treatment. For chronic diarrhea, the differential is much longer ...
Carter Patrick M PM University of Michigan Injury Center, Ann Arbor, Michigan; Department of Emergency Medicine, University of Michigan School of Medicine, Ann Arbor, Michigan; Department of Psychiatry, University of Michigan School of Medicine, Ann Arbor, Michigan. Electronic address: - - 2014
Adolescent drivers are at elevated crash risk due to distracted driving behavior (DDB). Understanding parental and peer influences on adolescent DDB may aid future efforts to decrease crash risk. We examined the influence of risk perception, sensation seeking, as well as descriptive and injunctive social norms on adolescent DDB using ...
Seidenfuss Anna A 1 Department of Radiology, University Erlangen-Nuremberg, Maximiliansplatz 1, Erlangen 91054, - - 2014
OBJECTIVE. Organ-based tube current modulation has been shown to significantly reduce the radiation dose to the female breast in phantom studies. We sought to assess the proportions of female breast and glandular tissues that are within the range of organ-based tube current modulation in different age groups and whether these ...
Ha Sohmyung - - 2014
This paper presents an overview of the fundamentals and state of the-art in noninvasive physiological monitoring instrumentation with a focus on electrode and optrode interfaces to the body, and micropower-integrated circuit design for unobtrusive wearable applications. Since the electrode/optrode-body interface is a performance limiting factor in noninvasive monitoring systems, practical ...
Laeger Inga I The Department of Psychiatry, University of Muenster, - - 2014
Altered memory processes are thought to be a key mechanism in the etiology of anxiety disorders, but little is known about the neural correlates of fear learning and memory biases in patients with social phobia. The present study therefore examined whether patients with social phobia exhibit different patterns of neural ...
Dutta Debarun D *BOptom †PhD, FAAO School of Optometry and Vision Science, The University of New South Wales, Sydney, New South Wales, Australia (DD, JO, MDPW); and Brien Holden Vision Institute, Sydney, New South Wales, Australia (DD, - - 2014
Covalent immobilization of antimicrobial peptide melimine onto contact lenses can produce broad-spectrum antimicrobial lenses. The purpose of this study was to investigate the performance of melimine-coated contact lenses in an animal model and human clinical trial. Melimine was covalently attached onto the surface of contact lenses via EDC (1-ethyl-3-[3-dimethylaminopropyl] carbodiimide ...
Pattini Linda - - 2014
Heart failure (HF) is a complex syndrome which can be the exit of different etiologies which lead to a common clinical picture. Treatment outcome is modest and new insights into pathophysiology are needed to improve effectively diagnosis, prognosis, and therapy. As a complex disease, it can really benefit from the ...
Whelihan Matthew F MF Division of Hematology/Oncology, Department of Medicine, University of NC at Chapel Hill, - - 2014
The prothrombotic nature of sickle cell disease (SCD) is evidenced by the chronically elevated levels of almost all coagulation activation biomarkers, and an increased incidence of certain thrombotic events, including venous thromboembolism. Numerous studies have attempted to define the extent and elucidate the mechanism of the observed increase in thrombin ...
Wright Jennifer J Division of General Internal Medicine, Department of Internal Medicine, General Internal Medicine Centre, University of Washington, Box 354760, 4245 Roosevelt Way Northeast, Seattle, WA 98105, USA. Electronic address: - - 2014
Fatigue is a common symptom in primary care with many causes ranging from benign to life threatening. Appropriate evaluation and management are guided by the patient's history, which provides valuable clues as to the source of the patient's symptoms. Ultimately a diagnosis may not be identified for many patients presenting ...
Potera Carol C Carol - - 2014
Offenders can be prosecuted in tribal courts beginning in March 2015.
Yuan Wei-Hsin WH 1 Division of Radiology, Taipei Municipal Gan-Dau Hospital, Taipei, Taiwan, Republic of - - 2014
The objective of our study was to evaluate the CT characteristics of globe rupture. The medical records of patients seen in the emergency department with blunt, penetrating, or explosive orbit injury were retrospectively reviewed. A total of 75 patients (76 injured globes) were included (56 males and 19 females; average ...
Wocial Lucia D LD Author Affiliations: Nurse Ethicist (Dr Wocial), Nursing Senior Marketing Coordinator (Ms Sego), Director of Market Research (Ms Rager), Nursing Project Coordinator (Ms Laubersheimer), Executive Vice President and Chief Nursing Executive (Dr Everett), Indiana University Health, - - 2014
The purpose of this qualitative study was to explore the meaning of the phrase "image of the nurse" in the context of the desired brand experience of assurance. A brand is a promise that lives in the minds of consumers. Nurses play a key role in delivering on the brand ...
Gouard S S INSERM UMR 892 - CRCNA, France; University of Nantes, France; CNRS UMR 6299, Nantes, - - 2014
Multiple myeloma (MM) is a B-cell malignancy of terminally differentiated plasma cells within the bone marrow. Despite intense research to develop new treatments, cure is almost never achieved. Alpha-radioimmunotherapy (RIT) has been shown to be effective in vivo in a MM model. In order to define where alpha-RIT stands in ...
Fiddler John B JB John B. Fiddler works as an NP on the Visiting Nurse Service of New York Haven Hospice Specialty Care Unit in New York City. Contact author: jbbfiddler@gmail.com. Reflections is coordinated by Madeleine Mysko, MA, RN: - - 2014
The author finds his ideal of nursing care in an inpatient hospice.
Wellman Ashley A Ashley Wellman is an assistant professor at the University of Central Missouri in Warrensburg, Mo. The author has disclosed no potential conflicts of interest, financial or - - 2014
About 18% of women and 3% of men report being a victim of sexual assault, but fewer than one-third of victims seek immediate medical attention or psychological counseling. Over time, victims may experience physical and emotional reactions and turn to primary care providers, who should be prepared to identify survivors ...
Itatani Ryo R 1 Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto University, 1-1-1, Honjo, Kumamoto, 860-8556, - - 2014
OBJECTIVE. The purpose of our study was to identify low-risk prostate cancer on the basis of the D'Amico clinical risk score in patients with prostate-specific antigen (PSA) levels 10 ng/mL or less who had undergone radical prostatectomy by comparing apparent diffusion coefficient (ADC) with transrectal ultrasound (TRUS)-guided target biopsy. MATERIALS ...
Mileto Achille A 1 Department of Radiology, Duke University Medical Center, Erwin Rd, Box 3808, Durham, NC - - 2014
OBJECTIVE. The objective of our study was to assess the accuracy of iodine-related attenuation and iodine quantification as imaging biomarkers of iodine uptake in renal lesions on a single-phase nephrographic image with dual-energy MDCT. MATERIALS AND METHODS. Fifty-nine patients (41 men, 18 women; age range, 28-84 years) with 80 renal ...
Adams Jeffrey M JM Author Affiliation: Director, The Center for Innovations in Care Delivery and Connell Nursing Research Scholar, Massachusetts General Hospital, - - 2014
This department highlights nursing leaders who have demonstrated a commitment to nursing leadership in research, practice, policy, education and theory. This interview profiles Donna Sullivan Havens, PhD, RN, FAAN, professor, The University of North Carolina at Chapel Hill.
Kittiskulnam Piyawan P Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, - - 2014
This study was conducted to examine the effects of weight reduction on proteinuria, adipokines, and renal function in overweight immunoglobulin A nephropathy (IgAN) patients (body mass index > 23 kg/m(2)) with chronic proteinuria more than 6 months. This was a single-center, prospective, randomized controlled trial. The study was performed at the outpatient ...
Boos Markus D MD Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; Section of Dermatology, Children's Hospital of Philadelphia, Philadelphia, - - 2014
We report six new cases of lipofibromatosis, an uncommon pediatric soft tissue neoplasm. This is the only series of patients to be described since the initial case series of 45 patients that characterized this entity in 2000. The purpose of this study was to characterize the presentation of lipofibromatosis to ...
Gailani David D Department of Pathology, Microbiology and Immunology, Vanderbilt University, Nashville, TN, United States. Electronic address: - - 2014
Factor XI (fXI) is the zymogen of a plasma protease, factor XIa (fXIa), that contributes to thrombin generation during blood coagulation by proteolytic conversion of factor IX (fIX) to factor IXaβ (fIXaβ). There is considerable interest in fXIa as a therapeutic target because it contributes to thrombosis, while serving a ...
Brandon Debra D Debra Brandon is PhD and Postdoctoral Program Director, Duke University School of Nursing; Associate Professor, Duke University School of Nursing and School of Medicine, Durham, NC. The author can be reached via e-mail at debra.brandon@duke.edu Donna Ryan is Clinical Instructor, Duke University School of Nursing, Durham, NC. Richard Sloane is Biostatistician, Center for Aging, Duke University School of Medicine, Durham, NC. Sharron L. Docherty is Associate Professor, School of Nursing; Associate Professor, Department of Pediatrics, School of Medicine; Co-Director, Adapt Center for Cognitive/Affective Symptom Science, Duke University School of Nursing, Durham, - - 2014
To evaluate the impact of the introduction of a new pediatric palliative care program on the pattern of moral distress in pediatric healthcare providers (HCPs). We used a before and after cross-sectional survey design to study the impact of the Pediatric Quality of Life (QoL) Program on the moral distress ...
Spronk Henri M H HM Laboratory for Clinical Thrombosis and Haemostasis, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands; Department of Internal Medicine, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands. Electronic address: - - 2014
It has been suggested that the main physiological trigger of coagulation, tissue factor, possesses limited procoagulant activity and occurs in an inactive or so-called encrypted state. For the conversion of encrypted into decrypted tissue factor with sufficient procoagulant activity, four distinct models have been proposed: 1; dimer formation, 2; lipid ...
Chu Linda C LC 1 The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Hospital, 601 N Caroline St, Baltimore, MD - - 2014
OBJECTIVE. Arterial dissection and aneurysm rupture are significant sources of morbidity and mortality in patients with connective tissue diseases. This article provides a detailed analysis of cardiovascular involvement in Marfan syndrome, Loeys-Dietz syndrome, and vascular Ehlers-Danlos syndrome. CONCLUSION. Although these syndromes share some overlapping features, they have discriminating clinical and ...
Granvall Stephanie A SA Stephanie A. Granvall is a surgical PA with Swedish Surgical Specialists at Swedish Hospital in Issaquah, Wash. The author has disclosed no potential conflicts of interest, financial or - - 2014
Femoral hernias occur in about 3% of all abdominal wall hernias. Herniation of the appendix through a femoral hernia (called de Garengeot hernia) is a much rarer finding, occurring in 0.8% to 1% of all cases. This unique surgical finding is most often found intraoperatively due to the similarities it ...
Lisy Karolina K Karolina Lisy is a research fellow at the Joanna Briggs Institute in the School of Translational Health Science, University of Adelaide, South Australia, and a member of the Cochrane Nursing Care - - 2014
This is a summary of a nursing care-related systematic review from the Cochrane Library.
Gentili Amilcare A 1 Department of Radiology, San Diego VA Healthcare System, UCSD, 3350 La Jolla Village Dr, San Diego, CA - - 2014
OBJECTIVE. Cost accounting is the branch of managerial accounting that deals with the analysis of the costs of a product or service. This article reviews methods of classifying and allocating costs and relationships among costs, volume, and revenues. CONCLUSION. Radiology practices need to know the cost of a procedure or ...
Fornage Bruno D BD 1 Department of Diagnostic Radiology, The University of Texas M. D. Anderson Cancer Center, Unit 1350, 1155 Pressler St, Houston, TX - - 2014
OBJECTIVE. The purpose of this article is to describe the use of transoral sonography in the diagnosis, fine-needle aspiration (FNA) biopsy, and intraoperative localization of retropharyngeal masses. MATERIALS AND METHODS. We reviewed images and data for eight patients with a retropharyngeal mass identified on CT, MRI, or PET/CT as being ...
Jenkins Peggy P Author Affiliations: Senior Director (Dr Jenkins), VHA, Inc, Irving, Texas; Professor, Director of PhD Program and Senior Scientist (Dr Welton), University of Colorado College of Nursing, - - 2014
The objective of the study was to measure the variability of direct nursing cost for similar patients and to examine the characteristics of nurses assigned to different types of patients. There is no standard method for measuring direct nursing cost by patient. Deidentified data were collected from 3 databases for ...
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