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Rasmus Stacy M SM Center for Alaska Native Health Research, Institute of Arctic Biology, University of Alaska Fairbanks, P.O. Box 757000, Fairbanks, AK, 99775, USA, - - 2014
The process that community based participatory research (CBPR) implementation takes in indigenous community contexts has serious implications for health intervention outcomes and sustainability. An evaluation of the Elluam Tungiinun (Towards Wellness) Project aimed to explore the experience of a Yup'ik Alaska Native community engaged within a CBPR process and describe ...
- - 2014
Cover: Diagram showing components of platelet biology important in cancer progression. See article by Sharma et al. on pages 1005-1015.
Kharadjian Talar B TB Department of Urology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 1373, Houston, TX, 77030, - - 2014
Inguinal lymph node dissection is a diagnostic and potentially curative treatment for penile carcinoma, which has historically been associated with high morbidity rates. This review summarizes the initial outcomes of robotic-assisted inguinal lymphadenectomy (RAIL) compared with the outcomes of the standard open and endoscopic approaches. The early experience suggests that ...
Hakky Tariq S TS University of South Florida, 2 Tampa General Circle, Tampa, FL, 33602, USA, - - 2014
Historically, early surgical treatment for erectile dysfunction involved the placement of rigid devices outside of the corpora cavernosa. This practice resulted in high rates of erosion and infection. Today, most urologists in the United States place an inflatable penile prosthesis (IPP) with an infection-retardant coating inside the corpora cavernosa. In ...
Yahagi K K CVPath Institute, Inc., Gaithersburg, MD, USA - - - 2014
Peripheral artery disease (PAD) is an emerging problem especially with aging population and increase in the incidence of diabetes and metabolic syndrome. The disease is histologically characterized by the presence of moderate to severe calcification and fibrous plaques as compared to coronary and carotid atherosclerotic disease, which are richer in ...
Bieniek Kevin F KF Department of Neuroscience, Mayo Clinic, Jacksonville, Florida2Mayo Graduate School, Mayo Clinic College of Medicine, Rochester, - - 2014
Expanded hexanucleotide repeats in C9ORF72 are a common genetic cause of frontotemporal dementia and amyotrophic lateral sclerosis. Repeat expansions have also been detected infrequently in other disorders, including Alzheimer disease, dementia with Lewy bodies, and parkinsonian disorders. A consecutive series of 31 cases from the brain bank for neurodegenerative disorders ...
Flores-Suárez Luis Felipe LF Primary Systemic Vasculitides Clinic, Instituto Nacional de Enfermedades Respiratorias, Calzada de Tlalpan 4502, Col. Sección XVI, Tlalpan, Mexico City, Mexico, - - 2014
The vasculitides are a group of protean diseases, some of which are caused by conditions including infections, other autoimmune diseases, or neoplasias. They are a challenge to the clinician, in terms of both diagnosis and therapy. No diagnostic criteria exist, although a multinational effort to develop them is in progress. ...
Gooren Louis J LJ VU University Medical Center, Amsterdam, The - - 2014
Hormonal treatment of transgender people is becoming a normal part of medicine, though numbers of subjects remain small because of low prevalence. Information on treatment is scattered and this review brings together the latest information on treatment goals and potential side-effects of androgen treatment of female-to-male transsexual subjects. Androgen treatment ...
Davis Margot M Division of Cardiovascular Medicine, Stanford University School of Medicine, 300 Pasteur Drive, Falk Cardiovascular Research Center #273, Stanford, CA, 94305-5406, - - 2014
Radiation-induced heart disease (RIHD) represents a spectrum of cardiovascular disease in patients who have undergone mediastinal, thoracic, or breast radiotherapy (RT). RIHD may involve any cardiac structure and is a major cause of morbidity and mortality in cancer survivors. While large cohort studies have demonstrated that symptomatic RIHD is a ...
Jayasuriya S S Dana 3 Cardiology, FACC Yale University New Haven, CT, USA - - - 2014
The prevalence of PAD is expected to increase as the population ages and the treatment for chronic disease becomes more sophisticated. The safety, efficacy, and lower cost of endovascular treatment for peripheral vascular disease of the lower extremities when compared with surgical revascularization are well known. Despite the clinical improvements ...
Vida V L VL Pediatric and Congenital Cardiac Surgery Unit Department of Cardiac, Thoracic and Vascular Surgery University of Padua, Padua, Italy - - - 2014
The aim of this study was to evaluate the efficacy and cost-effectiveness of fibrinogen/thrombin-coated collagen patch (FTCCP)(TachoSil®) during intraoperative hemostasis in patients with congenital heart disease, who required a reoperation during childhood. We reviewed data on the intraoperative blood product requirements and hospital costs of children (age <16 years) who ...
Franzone A A Division of Cardiology Department of Advanced Biomedical Sciences "Federico II" University, Naples, Italy - - - 2014
The treatment of in-stent restenosis (ISR) in the femoro-popliteal artery (FPA) is one of the major challenges of endovascular therapy, occurring in up to 40% of femoro-popliteal lesions treated with bare-metal stents within 1 year of treatment. Drug-eluting technologies, involving local delivery of paclitaxel, are providing a new paradigm for ...
Kirkley Andrew G AG Committee on Molecular Pathogenesis and Molecular Medicine, University of Chicago, Chicago, IL, - - 2014
Rates of metabolic diseases have increased at an astounding rate in recent decades. Even though poor diet and physical inactivity are central drivers, these lifestyle changes alone fail to fully account for the magnitude and rapidity of the epidemic. Thus, attention has turned to identifying novel risk factors, including the ...
Napier Catherine C Institute of Genetic Medicine, Newcastle University, and Endocrine Unit, Royal Victoria Infirmary, Newcastle upon Tyne, - - 2014
The purpose of this article is to review the current therapy of Addison's disease and to highlight recent developments in this field. Conventional steroid replacement for Addison's disease consists of twice or three-times daily oral hydrocortisone and once-daily fludrocortisone; however, new treatment modalities such as modified-released hydrocortisone and continuous subcutaneous ...
Schmid Marianne M Department of Urology, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, - - 2014
In 2008, urothelial carcinoma of the bladder (UCB) was the 8th most common cause of death in Germany. An increasing body of evidence suggests differences in the presentation and prognosis of UCB between genders. Large population-based and multi-institutional studies have found a higher incidence of UCB in men, while women ...
Lopez Jay Patrick JP Department of Medicine, University of Colorado at Denver, Denver, CO, - - 2014
Soft tissue sarcomas are a heterogenous group of malignancies with relatively high mortality rates. The outlook for these patients has been poor, with only a few drugs showing measurable activity. Trabectedin is a new alkylating agent with significant activity in sarcomas, but particularly in liposarcomas and leiomyosarcomas, both as a ...
Kirmani Batool F BF Epilepsy Center, Department of Neurology, Scott and White Neuroscience Institute, Temple, TX, USA, - - 2014
Elderly people are one of the fastest-growing populations in the United States, and the incidence of epilepsy in older people is much higher than in other population subgroups. This age group is the most vulnerable because of the increased incidence of multiple medical comorbidities, including stroke. The diagnosis of epilepsy ...
Singh G D GD University of California Davis Medical Center, Division of Cardiovascular Medicine and the Vascular Center Sacramento, CA, USA - - - 2014
Nitinol self-expanding stents are increasingly used to treat symptomatic peripheral arterial disease. Despite reduction in procedural complications and rates of stent fracture, femoropopliteal in-stent restenosis (FP-ISR) remains a common and important clinical problem. Due to heterogenous patient and angiographic characteristics, treatment of FP-ISR continues to evolve. Multiple modalities have been ...
Van den Berg J C JC Service of Interventional Radiology Ospedale Regionale di Lugano, Lugano, Switzerland - - - 2014
This paper will describe the technique of the treatment of in-stent restenosis of the infrainguinal arteries, using a combined technique of laser debulking followed by drug-eluting balloon angioplasty. The results of this technique from the literature will be discussed, and a comparison with other techniques that are currently used will ...
Beschorner U U Department Angiology University‑Heart Center Freiburg‑Bad Krozingen Bad Krozingen, Germany - - - 2014
Mechanical atherectomy for instent restenosis (ISR) seems to be limited by a low patency rate. This might be due to the mechanical trauma that induces an inflammatory response leading to recurrent ISR. Addition of drug eluting balloon angioplasty could overcome these challenges while preserving the advantages of a better acute ...
Kwan Alan C AC From the Department of Radiology and Imaging Sciences, National Institutes of Health Clinical Center, 10 Center Dr, Building 10/1C355, Bethesda, MD 20892 (A.C.K., G.C., C.T.S., K.R., D.A.B.); Intermountain Heart Institute, Intermountain Medical Center, Salt Lake City, Utah (H.T.M., D.L.L., J.B.M., J.L.A.); Cardiology Division, Department of Medicine, Johns Hopkins University, Baltimore, Md (B.D.R., J.A.C.L.); and Cardiology Division, University of Utah, Salt Lake City, Utah (D.L.L., J.B.M., - - 2014
Purpose To determine the relationship between coronary plaque detected with coronary computed tomographic (CT) angiography and clinical parameters and cardiovascular risk factors in asymptomatic patients with diabetes. Materials and Methods All patients signed institutional review board-approved informed consent forms before enrollment. Two hundred twenty-four asymptomatic diabetic patients (121 men; mean ...
Morita Kiyomi K Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, the University of Tokyo, Tokyo, - - 2014
Fluorescence imaging using indocyanine green (ICG) has recently been applied to laparoscopic surgery to identify cancerous tissues, lymph nodes, and vascular anatomy. Here we report the application of ICG-fluorescence imaging to visualize the boundary between the liver and subserosal tissues of the gallbladder during laparoscopic full-thickness cholecystectomy. A patient with ...
Yazici Ar - - 2014
SUMMARY The aim of the present study was to evaluate the three-year clinical performance of a nanofilled resin composite, a packable resin composite, and silorane-based resin restorations in Class I occlusal cavities. Twenty-eight patients with at least three similar-sized occlusal lesions in molar teeth participated in the study. A total ...
Sonneveld Milan J MJ Department of Clinical Neurophysiology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands; Department of Obstetrics and Gynecology, Division of Obstetrics and Perinatal Medicine, Erasmus MC, University Medical Center, Rotterdam, the - - 2014
Cerebral perfusion pressure (CPP) is elevated in preeclampsia, and may predispose to cerebrovascular complications and progression to eclampsia. We estimated zero flow pressure (ZFP) and CPP using simultaneously obtained arterial blood pressure and middle cerebral artery blood flow velocity in 10 women with preeclampsia, all treated with methyldopa with or ...
Higuera-de la Tijera Fátima F Gastroenterology Department, Hospital General de México, - - 2014
Background & Aim. Despite treatment with glucocorticoids, mortality remains high in patients with severe alcoholic hepatitis. Oxidative stress and depletion of mitochondrial glutathione are implicated factors in liver injury. The aim of this study was to evaluate the impact of the addition of metadoxine, a drug which possesses a multifactorial ...
Haugen Thomas A TA Faculty of Health and Sport Sciences, University of Agder, Kristiansand, - - 2014
Purpose: To quantify VO2max among female competitive soccer players as a function of performance level, field position, and age. In addition, the evolution of VO2max among world-class players over an 18-y period was quantified. Methods: Female players (N = 199, 22 ± 4 y, 63 ± 6 kg, height 169 ...
Doyle Francis J FJ 3rd Corresponding author: Francis J. Doyle III, - - 2014
In this two-part Bench to Clinic narrative, recent advances in both the preclinical and clinical aspects of artificial pancreas (AP) development are described. In the preceding Bench narrative, Kudva and colleagues provide an in-depth understanding of the modified glucoregulatory physiology of type 1 diabetes that will help refine future AP ...
Martínez-Sánchez Juan A JA Armada. Centro de Psicología de San - - 2014
Background: Spain was one of the first countries to recognize the importance of psychological aspects in the planning and development of international military operations, and also to include military psychologists in contingents deployed abroad. Method: This paper describes the psychological intervention model used by Spanish military psychologists involved in military ...
Beppu Toru T Department of Gastroenterological Surgery, Graduate School of Life Sciences, Kumamoto University, Kumamoto, Japan; Department of Multidisciplinary Treatment for Gastroenterological Cancer, Innovation Center for Translational Research, Kumamoto University Hospital, Kumamoto, - - 2014
Metachronous rectal liver metastasis (15 mm in segment 8 ventral) was managed with laparoscopic hepatectomy using segmental blood flow occlusion with radiofrequency ablation. During liver dissection, the ischemic area was visible as a distinct hypoechoic area on intraoperative enhanced ultrasound; with a photodynamic eye camera, it appeared as a discolored lesion. ...
Halpern Jonathan - - 2014
Context • The aging process is associated with physiological changes that affect sleep. In older adults, undiagnosed and untreated insomnia may cause impaired daily function and reduced quality of life (QoL). Insomnia is also a risk factor for accidents and falls that are the main cause of accidental deaths in ...
Collart Clara C Division of Systems Biology, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, - - 2014
The Xenopus mid-blastula transition (MBT) marks the onset of large-scale zygotic transcription, as well as an increase in cell cycle length and a loss of synchronous cell divisions. Little is known about what triggers the activation of transcription or how newly expressed genes interact with each other. Here, we use ...
Akubat Ibrahim I Dept of Physical Education and Sports Studies, Newman University, Birmingham, England, - - 2014
Purpose: This study aimed to assess the relationships of fitness in soccer players with a novel integration of internal and external training load (TL). Design: Ten amateur soccer players performed a lactate threshold (LT) test followed by a soccer simulation (Ball-Sport Endurance and Sprint Test [BEAST90mod]). Methods: The results from ...
Lehoux Juan J Department of Surgery, University of Rochester Medical Center, Strong Memorial Hospital, Rochester, NY, - - 2014
Left ventricular hypertrophy (LVH) frequently accompanies the progression of aortic valve disease in children. The extent of LVH regression following surgical relief of aortic valve disease in children has not been clearly elucidated. We hypothesized that significant regression of LVH will occur in children following the Ross procedure. We examined ...
García-Fernández José M JM University of - - 2014
Background: The School Anxiety Inventory (SAI) can be applied in different fields of psychology. However, due to the inventory's administration time, it may not be useful in certain situations. To address this concern, the present study developed a short version of the SAI (the SAI-SV). Method: This study examined the ...
Kor Daryl J DJ From the Department of Anesthesiology (D.J.K.), Department of Health Sciences Research (R.K.L., R.E.C.), and Department of Medicine, Division of Pulmonary and Critical Care Medicine (O.G.), Mayo Clinic, Rochester, Minnesota; Department of Surgery (P.K.P.) and Department of Anesthesiology (J.M.B.), University of Michigan School of Medicine, Ann Arbor, Michigan; Department of Surgery (H.L.A.), St Joseph Mercy Hospital, Ann Arbor, Michigan; Department of Emergency Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts (P.C.H.); Department of Surgery, Wake Forest University Health Sciences, Winston-Salem, North Carolina (J.J.H.); Departme nt of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts (E.K.B.); Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina (R.R.B.); Department of Anesthesiology, University of Texas Southwestern Medical Center, Dallas, Texas (A.A.); Department of Critical Care, Mayo Clinic, Jacksonville, Florida (E.F.); Department of Medicine, Albert Einstein College of Medicine, Bronx, New York (M.N.G.); and Department of Anaesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts - - 2014
Acute respiratory distress syndrome (ARDS) remains a serious postoperative complication. Although ARDS prevention is a priority, the inability to identify patients at risk for ARDS remains a barrier to progress. The authors tested and refined the previously reported surgical lung injury prediction (SLIP) model in a multicenter cohort of at-risk ...
Mimatsu Kenji K Department of Surgery, Social Insurance Yokohama Central Hospital, Yokohama, - - 2014
Laparoscopic Nissen fundoplication (LNF) and gastrostomy are often performed in children with gastroesophageal reflux disease. With a population that is increasingly aging, the number of elderly patients with paraesophageal hernia who have a nutritional disorder due to dysphagia has increased. In these patients with feeding difficulties, LNF and percutaneous endoscopic ...
Vather Ryash R Department of Surgery, University of Auckland, Auckland, New - - 2014
Postoperative ileus (POI) is an abnormal pattern of gastrointestinal motility characterized by nausea, vomiting, abdominal distension and/or delayed passage of flatus or stool, which may occur following surgery. Postoperative ileus slows recovery, increases the risk of developing postoperative complications and confers a significant financial load on healthcare institutions. The aim ...
Demirbilek Muge M Department of Medical Microbiology, Faculty of Medicine, Baskent University, Ankara, - - 2014
The antimicrobial effects of multipurpose contact lens solutions (MPSs) have been evaluated according to ISO 14729 standards. The aim of this study was to assess the efficacy of commercially available MPSs against extended-spectrum beta lactamases (ESBL)-producing Escherichia coli, methicillin-resistant Staphylococcus aureus (MRSA), and Candida albicans clinical isolates. Three commercially available ...
Figueiredo António J AJ Faculty of Sport Sciences and Physical Education, University of Coimbra, Coimbra, - - 2014
Being one of the most prominent globalized sports, soccer played at club, national, and continental levels has a relevant societal role. At present, the specific competencies, interests, and languages of the different actors involved in the selection, development, and support of long-lasting careers of players might limit opportunities for potential ...
Liu Aihai A Department of Gynecology, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, - - 2014
The objective of this study is to investigate and compare the effectiveness of letrozole and clomiphene citrate for improving fertility outcomes, including pregnancy rate, miscarriage rate, multiple pregnancy rate, and incidence rate of adverse events, number of dominant follicles, endometrial thickness at hCG day and serum E2 on hCG day. ...
Donovan Luke L Kinesiology Program, University of Virginia, Charlottesville, - - 2014
Context: Ankle-destabilization devices are rehabilitation tools that may improve neuromuscular control by increasing lower-extremity muscle activation. Their effects should be tested in healthy individuals before being implemented in rehabilitation programs. Objective: To compare EMG activation of lower-extremity muscles during walking while wearing 2 different ankle-destabilization devices. Design: Crossover. Setting: Laboratory. ...
Hovorka Roman R Corresponding author: Roman Hovorka, - - 2014
OBJECTIVE To evaluate feasibility, safety, and efficacy of overnight closed-loop insulin delivery in free-living youth with type 1 diabetes. RESEARCH DESIGN AND METHODS Overnight closed loop was evaluated at home by 16 pump-treated adolescents with type 1 diabetes aged 12-18 years. Over a 3-week period, overnight insulin delivery was directed ...
Segev Yakir Y *Familial Breast Cancer Research, Women's College Research Institute; †Department of Obstetrics and Gynecology, University of Toronto; ‡Department of Gynecologic Oncology, Princess Margaret Hospital; §Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada; ∥Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center, Tampa, FL; ¶Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT; and #Duke University, Duke School of Medicine, Durham, - - 2014
In a population-based sample of epithelial ovarian cancers, the objective of this study was to evaluate the association between microsatellite instability (MSI) status and the following factors: (1) ovarian cancer risk factors and (2) the distribution of the specific histologic subtypes. Participants were drawn from 3 population-based studies of primary ...
Takahashi Kayo K Department of Obstetrics and Gynecology, Jichi Medical University School of Medicine, Shimotsuke-shi, Tochigi, - - 2014
Our aim was to establish measurements of subcutaneous fat area ratio (SFAR) and visceral fat area ratio (VFAR) in the early second trimester using magnetic resonance imaging (MRI) in an obese pregnant cohort. Obesity was defined as pre-pregnancy body mass index of 25.0 or more. One hundred and twelve obese ...
Schnettler Morales Berta B Universidad de La - - 2014
Background: Eating is one of the most frequent human behaviors, but there are few studies that relate eating and subjective well-being. Typologies of people were distinguished and characterized according to their level of satisfaction with life and food in central Chile. Method: A survey was applied to a sample of ...
Munné María S MS Laboratorio Nacional de Referencia de Hepatitis Virales, Instituto Nacional de Enfermedades Infecciosas, ANLIS "Carlos G. Malbrán", Buenos Aires, - - 2014
By using molecular surveillance of hepatitis A virus, we characterized for the first time a subgenotype IB imported case in Argentina, a country with universal vaccination since 2005. The case was a crew member of a cruise ship. We consider this a case alert because of its multiple implications.
Fernandez-Montero Jose Vicente JV Hospital Carlos III, Department of Infectious Diseases , Madrid , Spain - - 2014
Introduction: Antiretroviral therapy has evolved dramatically and more potent, safer and convenient drugs have replaced former compounds. Dolutegravir (DTG) is the most recently approved integrase inhibitor. It displays attractive properties such as one pill once daily (QD) dosing, high barrier to resistance and clean safety profile. Moreover, it is planned ...
Vescovi Jason D JD School of Kinesiology and Health Science, York University, Toronto, ON, - - 2014
Purpose: To quantify the locomotor demands of college female soccer matches and compare the relative proportion of distances in specified velocity bands between players completing an entire half with substitutes. Methods: College female soccer players (n = 113) were assessed during a regular-season match using global positioning system technology. An ...
He Ji C JC New England College of Optometry, Boston, - - 2014
The purpose of this study was to theoretically model the contributions of corneal asphericity (Q) and anterior chamber depth to peripheral wavefront aberrations. Ray-tracing was performed on a model eye using a customised MatLab program to calculate Zernike aberrations up to the 5th order across ±60° of the horizontal visual ...
Ruiz Montse C MC 1 University of Jyväskylä - - 2014
Background: The aim of this study was to examine the psychometric properties of the Spanish version of the Sport Imagery Questionnaire (SIQ), which assesses cognitive and motivational functions of imagery use. Method: Participants were 361 athletes (234 male and 127 female) with a mean of age of 24.29 ± 7.76 ...
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