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Aitken Sarah J SJ Research Department of Pathology, UCL Cancer Institute, London, UK; Sarah Cannon/University College London Advanced Diagnostics Molecular Profiling Research Laboratories, London, UK; Department of Pathology, Addenbrooke's Hospital, Cambridge, - - 2014
Erdheim Chester disease (ECD) is a rare, non-Langerhans' cell histiocytic neoplastic disorder that usually presents in patients in their fifties. ECD often presents as a multi-system macrophagic infiltration and common sites of involvement are the central nervous system, cardiovascular system, respiratory system, retroperitoneum, and skin. Extra-skeletal involvement is usually responsible ...
Bednar Ingeborg - - 2014
The separation characteristics of molecules are determined by surface energies of monoliths. We produced monoliths as porous chromatographic columns and as non-porous sheets and compare two experimental methods: inverse liquid chromatography and contact angle measurements to determine the surface energies of both sample types. According to different retention times of ...
Romagnoli Marco M Universitary Research Institute "Dr. Viña Giner", Molecular and Mitochondrial Medicine, Catholic University of Valencia "San Vicente Mártir", c/Quevedo 2, 46001, Valencia, - - 2014
In recent years, several systems have been developed to control cardiac function during exercise, and some are also capable of recording RR data to provide heart rate variability (HRV) analyses. In this study we compare time between heart beats and HRV parameters obtained with a smart textile system (GOW; Weartech ...
Baran A A Department of Dermatology and Venereology Medical University of Bialystok, 15-540 Bialystok, Zurawia 14 St, - - 2014
Abstract Objectives: Psoriasis has been considered as a systemic disease associated with obesity, cardiovascular diseases and metabolic syndrome. Adipokines have influence on many metabolic processes. Aim of these study was to evaluate the effect of conventional topical treatment on serum adiponectin and leptin levels in patients with psoriasis. Methods: Forty-nine ...
Muelling Katharina K Max Planck Institute for Intelligent Systems, Spemannstr. 38, 72076 , Tuebingen, Germany, - - 2014
Learning a complex task such as table tennis is a challenging problem for both robots and humans. Even after acquiring the necessary motor skills, a strategy is needed to choose where and how to return the ball to the opponent's court in order to win the game. The data-driven identification ...
Coronado Eugenio E Instituto de Ciencia Molecular (ICMol), Universidad de Valencia, C/Catedrático José Beltrán 2, 46980 Paterna - - 2014
The present work reports the introduction of pyridine bisamine terdentate ligands in the structure of a pirouetting copper rotaxane. Rotaxane 2[PF6 ] constitutes the first example of the incorporation of imine-based dynamic covalent chemistry in the synthesis of switchable copper-complexed interlocked systems. In this rotaxane, the substitution of the classical ...
Sotiriou E E First Dermatology Department, Medical Schoool, Aristotle University Thessaloniki, Thessaloniki, - - 2014
Actinic damage is responsible for the development of multiple, recurrent non-melanoma skin cancers (NMSCs), including actinic keratoses (AKs). Photodynamic therapy (PDT) and imiquimod cream (IMIQ) 5% are recommended as field-directed treatment options. To compare efficacy and safety of methyl aminolevulinate (MAL)-PDT vs. IMIQ 5% in the prevention of new NMSCs ...
Horsch S S Department of Neonatology, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands, - - 2014
Cerebral developmental venous anomaly (DVA) is considered a benign anatomical variant of parenchymal venous drainage; it is the most common vascular malformation seen in the adult brain. Despite its assumed congenital origin, little is known about DVA in the neonatal brain. We report here the first cohort study of 14 ...
Teseo Serafino S Laboratoire d'Ethologie Expérimentale et Comparée, EA4443, Université Paris 13, Sorbonne Paris Cité, 99 avenue J.B. Clément, Villetaneuse, 93430, France, - - 2014
Although cuticular hydrocarbons (CHCs) have received much attention from biologists because of their important role in insect communication, few studies have addressed the chemical ecology of clonal species of eusocial insects. In this study we investigated whether and how differences in CHCs relate to the genetics and reproductive dynamics of ...
Nunes Renato Hoffmann RH Division of Neuroradiology, Fleury Medicina e Saúde, São Paulo, Brazil, - - 2014
We hypothesised that disorders with anterior temporal lobe (ATL) cysts might exhibit common peculiarities and distinguishable imaging features that could be useful for diagnosis. We reviewed a series of patients for neuroimaging contributions to specific diagnoses. A literature search was conducted, and institutional imaging files were reviewed to identify MR ...
Yang Hao - - 2014
In an effort to characterize the roles of each metal ion in metallo-beta-lactamase NDM-1, heterodimetallic analogs (CoCo-, ZnCo-, and CoCd-) of the enzyme were generated and characterized. UV-visible, 1H NMR, EPR and EXAFS spectroscopies were used to confirm the fidelity of the metal substitutions, including the presence of a homogeneous, ...
Moon Deok Hyun DH Department of Environmental Engineering, Chosun University, Gwangju, 501-759, Republic of Korea, - - 2014
Quality improvement of acidic soil (with an initial pH of approximately 4.5) with respect to soil pH, exchangeable cations, organic matter content, and maize growth was attempted using natural (NSF) and calcined starfish (CSF). Acidic soil was amended with NSF and CSF in the range of 1 to 10 wt.% to ...
Ambure Pravin P Jadavpur University, Department of Pharmaceutical Technology, Drug Theoretics and Cheminformatics Laboratory , Kolkata 700032 , India kunalroy_in@yahoo.com , - - 2014
Introduction: Alzheimer's disease (AD) is one of the lethal diseases, mainly affecting older people. The unclear root cause and involvement of various enzymes in the pathological conditions confirm the complexity of the disease. Quantitative structure-activity relationship (QSAR) techniques are of great significance in the design of drugs against AD. Areas ...
Barjhoux Iris I EPOC UMR CNRS 5805, Université de Bordeaux, Avenue des Facultés, 33405, Talence, Cedex,, - - 2014
Japanese medaka (Oryzias latipes) embryos were exposed to sediments spiked with environmental concentrations (300 and 3,000 ng/g dry weight) of pyrene (Pyr) and methylpyrene (MePyr) throughout their development. Embryotoxicity, teratogenicity, and transcriptional responses (qRT-PCR) were analyzed in embryos and newly hatched larvae. The genotoxicity of the two polycyclic aromatic hydrocarbons (PAHs) ...
Prozument Kirill K Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, MA 02139, USA. prozument@mit.edu - - 2014
A Chirped-Pulse millimeter-Wave (CPmmW) spectrometer is applied to the study of chemical reaction products that result from pyrolysis in a Chen nozzle heated to 1000-1800 K. Millimeter-wave rotational spectroscopy unambiguously determines, for each polar reaction product, the species, the conformers, relative concentrations, conversion percentage from precursor to each product, and, ...
Nunes Margarida M CFE-Centre for Functional Ecology, Department of Life Sciences, University of Coimbra, Apartado 3046, 3001-401, Coimbra, Portugal, - - 2014
Superficial sediments collected from seven estuarine systems located along the Portuguese coast were analyzed for 7 polychlorinated dibenzo-p-dioxins (PCDDs), 10 polychlorinated dibenzofurans (PCDFs), and 12 dioxin-like polychlorinated biphenyls (dl-PCBs). Total PCDD/F concentration ranged from 4.6 to 464 pg g(-1) dry weight (dw), while that of dl-PCBs varied from 26.6 to 8,693 pg g(-1) dw. ...
Ross David M DM Haematology Directorate, SA Pathology, Adelaide, SA, Australia; School of Medicine, University of Adelaide, Adelaide, SA, Australia; Flinders University and Medical Centre, Bedford Park, SA, - - 2014
Treatment-free remission (TFR) has recently emerged as a goal of treatment in chronic myeloid leukaemia (CML). Molecular remission is sustained in around 30% of imatinib-treated patients who stop treatment after ≥2 years with undetectable minimal residual disease (UMRD) by conventional real-time reverse transcription polymerase chain reaction. An additional 20-30% of patients ...
Leethongdee S S Faculty of Veterinary Sciences, Mahasarakham University, Amphur Muang, Mahasarakham, - - 2014
During the periovulatory period, the cervix relaxes in response to changes in circulating concentrations of reproductive hormones. The present study investigated the role of gonadotrophins in cervical function by examining the expression of follicle-stimulating hormone receptor (FSHR) and luteinizing hormone receptor (LHR) and their mRNAs following intracervical treatment with either ...
Ren Dongliang D Department of General Surgery, Dalian Medical University, Liaoning Province, - - 2014
Metastasis of tumor cells is the most deadly attribute of breast cancer patients. Aberrant sialylation is closely associated with malignant phenotype of tumor cells, including invasiveness and metastasis. The objective of this study is to clarify the possible role and mechanism of ST6GalNAcII in the metastasis process of breast carcinoma. ...
Wang Lichen L Department of Chemistry, Shanghai Key Laboratory of Molecular Catalysts and Innovative Materials, Fudan University, Shanghai 200433, China. mfzhou@fudan.edu.cn - - 2014
The infrared spectra of mass-selected mononuclear copper nitrosyl cation complexes [Cu(NO)n](+) with n = 1-5 and their argon tagged complexes are measured via infrared photodissociation spectroscopy in the nitrosyl stretching frequency region in the gas phase. The experimental spectra provide distinctive patterns allowing the determination of the geometries and electronic ...
Yin Shutong S Institute of Animal Nutrition, Northeast Agricultural University , Harbin , P.R. - - 2014
Abstract Context: Zearalenone (ZEN) is a common contaminant that is present in feedstuff of high humidity and high temperatures. Objective: The aim of this study was to investigate the effects of diets contaminated with different concentrations of ZEN on immunomodulation in early pregnant rats. Materials and methods: Forty-eight pregnant Sprague ...
Bhardwaj Jyoti J Department of Biotechnology - - 2014
Abstract The anti-cancer activity of saponins and phenolic compounds present in green tea was previously reported. However, the immunomodulatory and adjuvanticity activity of tea saponin has never been studied. In this study, we investigated the immunomodulatory effect of tea saponin in T-lymphocytes and EL4 cells via regulation of cytokine response ...
Vitlic Ana A School of Sport and Exercise Sciences, University of Birmingham, UK; MRC-Arthritis Research UK Centre for Musculoskeletal Ageing Research, University of Birmingham, - - 2014
This analysis examines whether or not younger caregivers, parents of children with developmental disabilities, differed from controls in terms of cytomegalovirus (CMV) seropositivity and CMV-specific antibody titre. Secondly, it examined whether any particular socio-demographics, health behaviours, or psychological/caregiving variables were associated with a higher CMV antibody titre among caregivers. Young ...
Nezic Lana L Division of Clinical Pharmacology and Toxicology, University Hospital Basel, 4031, Basel, - - 2014
Therapeutic drug monitoring of patients receiving once daily aminoglycoside therapy can be performed using pharmacokinetic (PK) formulas or Bayesian calculations. While these methods produced comparable results, their performance has never been checked against full PK profiles. We performed a PK study in order to compare both methods and to determine ...
Zuo Wu W Ministry of Education of Key Laboratory of Energy Thermal Conversion and Control, School of Energy and Environment, Southeast University, Nanjing, 210096, China, - - 2014
To research the impact of adding sawdust on top phase oil, a sewage sludge and poplar sawdust co-pyrolysis experiment was performed in a fixed bed. Gas chromatography (GC)/mass spectrometry (MS) was used to analyze the component distribution of top phase oil. Higher heating value, viscosity, water content, and pH of ...
Piconese Silvia S Dipartimento di Medicina Interna e Specialità Mediche, "Sapienza" Università di Roma, Policlinico Umberto I, 00161, Rome, - - 2014
Regulatory T cells (Tregs) can be considered as a mixed population of distinct subsets, endowed with diverse extent and quality of adaptation to microenvironmental signals. Here we uncovered an opposite distribution of Treg expansion, phenotype and plasticity in different microenvironments in the same organ (liver) derived from patients with chronic ...
Pottegård Anton A Clinical Pharmacology, Institute of Public Health, University of Southern Denmark, JB Winsløwsvej 19, 2, 5000, Odense C, Denmark, - - 2014
The aim of this study was to describe primary non-adherence (PNA) in a Danish general practitioner (GP) setting, i.e. the extent to which patients fail to fill the first prescription for a new drug. We also assessed the length of time between the issuing of a prescription by the GP ...
Akhmat Ghulam G College of Public Administration, Huazhong University of Science and Technology (HUST), 1037, Luoyu Road, Wuhan, People's Republic of China, - - 2014
The objective of the study is to empirically examine the air pollution, greenhouse gas (GHG) emissions and low birth weight in Pakistan through the cointegration and error correction model over a 36-year time period, i.e., between 1975 and 2012. The study employed the Johansen cointegration technique to estimate the long-run ...
Patel Dipal M DM Department of Pathology, Northwestern University Feinberg School of Medicine , Chicago, IL , - - 2014
Desmosomes have long been appreciated as intercellular junctions that are vital for maintaining the structural integrity of stratified epithelia. More recent clinical investigations of patients with diseases such as arrhythmogenic cardiomyopathy have further highlighted the importance of desmosomes in cardiac tissue, where they help to maintain coordination of cardiac myocytes. ...
Chauhan Divya D Centre for Environmental Science and Engineering, Indian Institute of Technology Kanpur, Kanpur, U.P., 208016, - - 2014
Enhanced removal application of both forms of inorganic arsenic from arsenic-contaminated aquifers at near-neutral pH was studied using a novel electrospun chitosan/PVA/zerovalent iron (CPZ) nanofibrous mat. CPZ was carefully examined using scanning electron microscopy (SEM) equipped with energy-dispersive X-ray analysis (EDX), transmission electron microscopy (TEM), atomic fluorescence spectroscopy (AFM), X-ray ...
Burti Juliana Schulze JS Department of Urology, Federal University of São Paulo, São Paulo, - - 2014
To compare pelvic floor muscles (PFMs) performance in women with and without stress urinary incontinence (SUI) during endurance test. It is a prospective case-control clinical trial. After determining PFM maximal voluntary contraction (MVC) by electromyography (EMG), women underwent endurance test, which consisted of consecutively PFM 1-sec fast contractions reaching MVC ...
van Schooten Kipp J KJ Department of Physics and Astronomy, University of Utah, 115 South 1400 East, Salt Lake City, UT 84112-0830 - - 2014
Blinking of colloidal nanocrystal quantum dots, random intermittency in the stream of photons emitted by single particles, has long commanded the curiosity of researchers. Why does the particle suddenly shut off, and what are the pathways to quench emission? Single-particle microscopy is not the only way to approach these fundamental ...
Shen Rong R Department of Epidemiology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas; Department of Chemotherapy, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, - - 2014
Thymidylate synthase (TYMS) plays a crucial role in folate metabolism as well as DNA synthesis and repair. We hypothesized that functional polymorphisms in the 3' UTR of TYMS are associated with gastric cancer risk and survival. In the present study, we tested our hypothesis by genotyping three potentially functional (at ...
López-Solà Clara C Bellvitge Biomedical Research Institute-IDIBELL, Department of Psychiatry, Hospital de Bellvitge, Barcelona, Spain; Department of Clinical Sciences, Bellvitge Campus, University of Barcelona, Barcelona, Spain; CIBERSAM (Centro de Investigación en Red de Salud Mental), Carlos III Health Institute, Madrid, - - 2014
While past twin studies indicate moderate levels of heritability of "obsessive-compulsive related" and anxiety disorder symptoms, no single study has reported such estimates in the same twin population nor examined potential genetic sex differences. We assessed symptoms of obsessive-compulsive disorder, body dysmorphic disorder, hoarding disorder, hypochondriasis, panic disorder, social phobia ...
Donateo Antonio A Istituto di Scienze dell'Atmosfera e del Clima, ISAC-CNR, 73100, Lecce, Italy, - - 2014
In this work, an assessment of the impact of ship traffic and related harbour activities (loading/unloading of ships and hotelling in harbour) on PM 2.5 and particle number concentrations (PNC) separating the contribution associated to ship traffic from that of harbour-related activities is reported. Further, an assessment of the impact ...
Belli Maria Luisa ML Medical Physics, Ospedale San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milano, - - 2014
To quantitatively assess the predictive power of early variations of parotid gland volume and density on final changes at the end of therapy and, possibly, on acute xerostomia during IMRT for head-neck cancer. Data of 92 parotids (46 patients) were available. Kinetics of the changes during treatment were described by ...
Schiller Kilian K Department of Radiation Oncology, Technische Universität München Klinikum rechts der Isar, Ismaningerstr. 22, 81675, München, - - 2014
The goal of this study was to assess the impact of different setup approaches in image-guided radiotherapy (IMRT) of the prostatic gland. In all, 28 patients with prostate cancer were enrolled in this study. After the placement of an endorectal balloon, the planning target volume (PTV) was treated to a dose ...
Su Bo B State Key Laboratory of Elemento-Organic Chemistry, Research Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, People's Republic of China. wang98h@263.net - - 2014
A new asymmetric total synthesis of a phenanthroindolizidine alkaloid (S)-tylophorine is reported, which features a catalytic asymmetric allylation of aldehydes and an unexpected one-pot DMAP promoted isocyanate formation and Lewis acid catalyzed intramolecular cyclization reaction. In addition, White's direct C-H oxidation catalyst system converting monosubstituted olefins to linear allylic acetates ...
Laas Kariina K Department of Psychology, University of Tartu, - - 2014
The functional polymorphism Asn(107) Ile (rs324981, A > T) of the neuropeptide S receptor (NPSR1) gene is involved in the modulation of traits that affect alcohol use. Hence, we have examined whether the NPSR1 A/T polymorphism is associated with alcohol use disorders (AUD) and alcohol use in a population-representative sample. Lifetime AUD were ...
Ye Lumeng L Department of Bioengineering Sciences, Research Group Microbiology, VIB Structural Biology, Vrije Universiteit Brussel, Pleinlaan 2, 1050, Brussels, - - 2014
All fluorescent pseudomonads (Pseudomonas aeruginosa, P. putida, P. fluorescens, P. syringae and others) are known to produce the high-affinity peptidic yellow-green fluorescent siderophore pyoverdine. These siderophores have peptide chains that are quite diverse and more than 50 pyoverdine structures have been elucidated. In the majority of the cases, a Pseudomonas ...
Elliott C D CD Department of Communication and Culture, University of Calgary, Calgary, - - 2014
Sugar and sodium levels in packaged foods is a critical consideration when it comes to the public health of Americans, yet little is known about the sugar and salt contained in packaged foods targeted at our youngest consumers. To examine the sugar and sodium content of packaged baby and toddler ...
Alkhalaf A A Diabetes Centre, Isala Clinics, Dr. Spanjaardweg 11, P.O. Box 10400, 8000 GK, Zwolle, The - - 2014
Homozygosity for a 5-leucine repeat (5L-5L) in the carnosinase gene (CNDP1) has been associated with a reduced prevalence of diabetic nephropathy in cross-sectional studies in patients with type 2 diabetes, particularly in women. Prospective studies on mortality are not available. This study investigated whether 5L-5L was associated with mortality and ...
Sawada Takako T Faculty of Food and Nutritional Sciences, Toyo University, Gunma, - - 2014
Iron deficiency without anemia (IDNA), the most prevalent nutritional deficiency worldwide, affects young women of reproductive age. This study aimed to elucidate the relationship between IDNA and mental and somatic symptoms including anger and fatigue using the Japanese version of the Cornell Medical Index Health Questionnaire (CMI-J). Data regarding demographic ...
Montañez-Barragán Alejandra A Escuela Superior de Medicina del Instituto Politécnico Nacional, Ciudad de México, - - 2014
Vascular calcification in chronic kidney disease (CKD) patients is associated to increased mortality. Osteoprotegerin (OPG) is a soluble tumor necrosis factor (TNF) superfamily receptor that inhibits the actions of the cytokines receptor activator of nuclear factor kappa-B ligand (RANKL) and TNF-related apoptosis-inducing ligand (TRAIL) by preventing their binding to signaling ...
Ma Maggie Kam Man MK Department of Medicine, University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong, - - 2014
Chronotropic incompetence (CI) is an independent predictor of cardiovascular events and overall mortality. The prevalence and significance of CI in renal transplant patient has not been examined. 38 non-heart failure renal transplant recipients were recruited for a transthoracic echocardiogram and treadmill stress test using the modified Bruce protocol. 15 patients ...
Maixnerova Dita D Department of Nephrology, 1st Faculty of Medicine, Charles University, U Nemocnice 2, 128 08, Prague 2, Czech Republic, - - 2014
We describe data on 10,472 renal biopsies gathered by the Czech Registry of Renal Biopsies over a period of 18 years. We assessed the main demographic, clinical and histological data of individuals who underwent renal biopsies of native kidneys in 31 centers in the Czech Republic (population 10.3 million) during the ...
Vergano Luca L Division of Otorhinolaryngology, University Hospital Città della Salute e della Scienza di Torino, Turin, - - 2014
The benefits of tonsillectomy in IgA nephropathy (IgAN) are still debated. Tonsillectomy may remove pathogen sources and reduce the mucosal associated lymphoid tissue (MALT), limiting degalactosylated IgA1 (deGal-IgA1) production, which is considered to be the initiating pathogenetic event leading to IgA glomerular deposition. In the European network VALIGA, 62/1147 IgAN ...
Houssami Nehmat N Screening and Test Evaluation Program (STEP), School of Public Health, Sydney Medical School, University of Sydney, Sydney, Australia; Royal Hospital for Women, Sydney, - - 2014
The optimal margin in breast-conserving surgery is controversial, and re-excision is common. Pathologic margin assessment is not standardized, and tumor biology and the use of systemic therapy have a major impact on local control. A study-level meta-analysis found no difference in local recurrence for margin widths of 1, 2, and ...
Gilman Jodi M JM Center for Addiction Medicine, Massachusetts General Hospital, Boston, MA, - - 2014
Substance use disorder is characterized by a transition from volitional to compulsive responding for drug reward. A possible explanation for this transition may be that alcohol-dependent patients (ADP) show a general propensity for a history of rewarded instrumental responses, and these rewarded responses may boost the activation of motivational neurocircuitry ...
Xu Tao T Department of Chemistry and Biochemistry, University of Texas at Austin, 1 University Station A5300, Austin, TX, 78712-0165, - - 2014
With the advent of new synthetic methodologies, carbon-carbon bond (C-C) activation strategies have uncovered not only new fundamental reactivity but also the potential for use as a highly efficient synthetic protocol. This chapter specifically discusses the use of four-membered ketone-based starting materials for C-C activation initiated transformations using a variety ...
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