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Park Joon Mo JM Division of Gastroenterology and Hepatology, Department of Internal Medicine, Yeugnam University College of Medicine, Daegu, - - 2014
Plummer-Vinson syndrome manifests as cervical dysphagia, iron deficiency anemia, an upper esophageal web, and atrophic glossitis. The cause of the esophageal web is thought to be iron deficiency anemia; however, the cause of Plummer-Vinson syndrome has not been established. Crohn's disease is usually accompanied by malnutrition and iron deficiency anemia; ...
Hwang Soon Woo SW Department of Internal Medicine, Hanyang University Guri Hospital, Guri, - - 2014
Duodenal variceal bleeding in patients with portal hypertension due to cirrhosis or other causes is uncommon. We report on a case of a 55-year-old male with an ectopic variceal rupture at the distal fourth part of the duodenum who presented with massive hematochezia and shock. Shortly after achievement of hemodynamic ...
Nagaraja Raghavendra R Department of Surgical Gastroenterology and Liver Transplantation, Manipal Hospital, 98, HAL Airport Road, Bengaluru, 560 017, India, - - 2014
Complications following liver transplantation requiring readmission may be serious and potentially life threatening. Most reports on readmission have been about after deceased donor liver transplantation (DDLT). We hypothesized that readmission after living donor liver transplantation (LDLT) is due to different reasons and analyzed our experience. We retrospectively analyzed the records ...
Goel Ashish A Department of Hepatology, Christian Medical College, Vellore, 632 004, - - 2014
We have reported A disintegrin and metalloprotease with thrombospondin type 1 motif, member 13 (ADAMTS13) deficiency in noncirrhotic intrahepatic portal hypertension (NCIPH) patients of European origin with preserved liver function. We aimed to study ADAMTS13-von Willebrand factor (vWF) imbalance in Indian patients with NCIPH. Twenty-nine cases with NCIPH [22 males; ...
Agah Shahram S Colorectal Research Center, Rasool-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran, - - 2014
About 10 % of cirrhotic patients are unresponsive to sodium restriction and diuretics and develop refractory ascites. Such patients usually require recurrent large-volume paracentesis and lots of hospital admissions. Hereby, we introduce a method applying a central vein (CV) catheter for large-volume paracentesis in patients with refractory ascites in up to ...
Burke Jeffrey D JD Western Psychiatric Institute and Clinic, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA, 15213, USA, - - 2014
Among the available treatments for disruptive behavior problems, a need remains for additional service options to reduce antisocial behavior and prevent further development along delinquent and violent pathways. The Stop Now and Plan (SNAP) Program is an intervention for antisocial behavior among boys between 6 and 11. This paper describes ...
Lobenhoffer P P SportsClinic Germany, Uhlemeyerstr. 16, 30175, Hannover, Deutschland, - - 2014
Frontal plane deformities result in significant overload of the (ipsilateral) affected compartment of the knee and in rapid progression of osteoarthritis. The indication for osteotomy around the knee is related mainly to the constitutional metaphyseal deformity in the frontal plane. Exact analysis and planning based on a long-leg standing radiograph ...
Jeon Byeong Tak BT Department of Neurological Surgery, Mayo Clinic, Rochester, MN, 55905, - - 2014
Obesity-induced fatty liver disease is associated with increased hypothalamic inflammation. Previous reports have demonstrated that the deletion of SIRT1 in hepatocytes increases hepatic steatosis and inflammation. Using myeloid cell-specific SIRT1 knockout (KO) mice, we investigated whether ablation of SIRT1 in macrophages plays a role in regulating hepatic steatosis and hypothalamic ...
Mahnken A H AH Klinik für Diagnostische und Interventionelle Radiologie, Universitätsklinikum, Philipps-Universität Marburg, Baldingerstr., 35043, Marburg, Deutschland, - - 2014
The management of solitary lung nodules poses a common clinical problem and biopsy is oftten required. Several guidelines provide slightly different recommendations and there are no uniform recommendations regarding the ideal technique of puncture guidance (e.g. percutaneous versus bronchoscopic or thoracoscopic). Fine needle aspiration biopsy (FNA) and core biopsy are ...
Guellich Aziz A INSERM UMR-S 769, LabEx LERMIT, Châtenay-Malabry, - - 2014
Cyclic AMP regulates a multitude of cellular responses and orchestrates a network of intracellular events. In the heart, cAMP is the main second messenger of the β-adrenergic receptor (β-AR) pathway producing positive chronotropic, inotropic, and lusitropic effects during sympathetic stimulation. Whereas short-term stimulation of β-AR/cAMP is beneficial for the heart, ...
Fecteau Heather H The Medical Center of Plano, 1600 Coit Rd Suite 204, Dallas, TX, USA, - - 2014
Cancer genetics professionals face a new opportunity and challenge in adapting to the availability of cancer genetic testing panels, now available as a result of Next Generation Sequencing (NGS) technology. While cancer panels have been available for over a year, we believe that there is not yet enough data to ...
Do Sung-Im SI Department of Pathology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, - - 2014
Integrins are cell surface receptors that mediate cell-cell/extracellular interactions and have shown an association with metastasis or transformation in several cancers. However, the correlation between the clinicopathological status of breast cancer and the altered integrin α4 status is not clear. In this study, we investigated DNA methylation of integrin α4 ...
Kang Jie J Center of Thyroid and Parathyroid, Department of General Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Yishan Road No. 600, Xuhui District, 200000, Shanghai, People's Republic of - - 2014
We conducted the meta-analysis of all relevant case-control studies aiming to evaluate the relationships of common polymorphisms in forkhead box E1 (FOXE1) and ataxia telangiectasia mutated (ATM) genes to the risk of papillary thyroid carcinoma (PTC). A range of electronic databases were searched without language restrictions: Web of Science (1945 ~ 2013), ...
Balzer Jan C JC Heinrich-Heine-University Dusseldorf, Dusseldorf, - - 2014
Aims: Introduction of a novel contrast injection protocol during rotational C-arm CT (RCT) in cardiac catheterisation of patients with aortic stenosis for aortic root assessment. Methods and results: Fifty-two patients underwent RCT imaging with contrast injection performed either into the aorta (Ao-RCT, n=25) or into the left ventricle (LV-RCT, n=27). ...
Yun Xiaoyan X Key Laboratory of Aquatic Botany and Watershed Ecology, Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan, 430074, - - 2014
Organochlorine pesticides (OCPs) are ubiquitous pollutants, and their presence in urban lakes is a concern for human and ecological health. Surface sediments in the East Lake, China, were collected in winter 2012 and summer 2013 to investigate concentrations, distribution patterns, possible sources, and potential ecological risks of OCPs in this ...
Anjum Naser A NA Department of Botany, Faculty of Science, Hamdard University, New Delhi, 110062, - - 2014
This study, based on a greenhouse pot culture experiment conducted with 15-day-old rapeseed (Brassica campestris L. cv. Pusa Gold; family Brassicaceae) and moong bean (Vigna radiata L. Wilczek cv. Pusa Ratna; family Fabaceae) plants treated with cadmium (Cd) concentrations (0, 50, and 100 mg kg(-1) soil), investigates their potential for Cd accumulation ...
Boleda M Rosa MR Aigües de Barcelona, S.A. General Batet 5-7, 08028, Barcelona, - - 2014
Fifty samples of finished drinking waters (FDWs) from Spain covering 12 million inhabitants were tested for 53 pharmaceuticals pertaining to 12 different Anatomical Therapeutic Chemical (ATC) classification system codes. The studied compounds are a combination of most commonly consumed pharmaceuticals with other barely reported in the literature. Five compounds, azithromycin, ...
Tzifa Aphrodite A Department of Congenital Heart Disease, Mitera Children's Hospital, Athens, - - 2014
Aims: Transcatheter implantation of valved stents (Melody and Edwards valves) for replacement of the pulmonary valve is currently an established procedure. We reviewed our experience on implantation of such valves in the tricuspid valve position. Methods and results: Transcatheter valve implantation in the tricuspid position was attempted in five patients. ...
Ayoub George M GM Civil and Environmental Engineering Department, American University of Beirut, Beirut, - - 2014
Laboratory experiments were carried out to study the effects of slow mixing conditions on magnesium hydroxide floc size and strength and to determine the turbidity and total suspended solid (TSS) removal efficiencies during coagulation of highly turbid suspensions. A highly turbid kaolin clay suspension (1,213 ± 36 nephelometric turbidity units (NTU)) was alkalized ...
Gago-Tinoco Amanda A Department of Chemistry and Material Science, Faculty of Experimental Sciences, University of Huelva, Campus de El Carmen, 21007, Huelva, - - 2014
Bioindicators can reflect the effects of pollutants on their metabolism, being widely used to assess environmental stress. In this sense, the crab Procambarus clarkii has been previously proposed to monitor the contamination in Doñana National Park (southwest Spain) using conventional biomarkers. In this work, a metabolomic approach based on direct ...
Rong Yao Y College of Life Science and Bioengineering, Beijing University of Technology, Beijing, People's Republic of China, - - 2014
Voluntary motor performance is the result of cortical commands driving muscle actions. Corticomuscular coherence can be used to examine the functional coupling or communication between human brain and muscles. To investigate the effects of grip force level on corticomuscular coherence in an accessory muscle, this study proposed an expanded support ...
Kimura Amanda A Department of Medicine, University of Washington, 325 9th Avenue, Seattle, WA, 98104, - - 2014
Vietnamese Americans are the fourth largest Asian ethnic group in the USA. Colorectal cancer (CRC) ranks as one of the most common cancers in Vietnamese Americans. However, CRC screening rates remain low among Vietnamese Americans, with 40 % of women and 60 % of men reporting never having a sigmoidoscopy, colonoscopy, or ...
Mukai Shuntaro S Department of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan, - - 2014
Recently, several endoscopists have described the usefulness of the endoscopic ultrasonography (EUS)-guided, single transluminal gateway technique (SGT) using transmural placement of single or multiple plastic stents or metal stents for a pancreatic pseudocyst (PC) and walled-off necrosis (WON). Moreover, the uses of the multiple transluminal gateway technique (MTGT) and single ...
Sommer G G Klinik für Radiologie und Nuklearmedizin, Universitätsspital Basel, Petersgraben 4, 4031, Basel, Schweiz, - - 2014
Due to physical and technical limitations, magnetic resonance imaging (MRI) has hitherto played only a minor role in image-based diagnostics of the lungs. However, as a consequence of important methodological developments during recent years, MRI has developed into a technically mature and clinically well-proven method for specific pulmonary questions. The ...
Huang Yanling Y College of Life Science and Technology, Southwest University for Nationalities, Chengdu, 610041, Peoples' Republic of China, - - 2014
To evaluate the effects of copper (Cu) supplementation on the serum lipid profile, meat quality, and carcass composition of goat kids, thirty-five 3-4-month-old Jian Yang big-eared goat kids (BW 20.3 ± 0.6 kg) were randomly assigned to one of seven dietary Cu treatments (n = 5/treatment). The dietary Cu concentrations were: (1) control (no supplemental ...
Moore Heather K HK Be The Match® Patient and Health Professional Services, 3001 Broadway Street NE, Minneapolis, MN, 55413, USA, - - 2014
Be The Match® Patient and Health Professional Services (PHPS) supports patients undergoing hematopoietic cell transplant (HCT) and caregivers by providing educational programs and resources. HCT is a potentially curative therapy for blood cancers such as leukemia and lymphoma. To help meet the increasing demand for support services, PHPS implemented a ...
Zeng Qiqun Q Key Laboratory of Protein and Peptide Pharmaceuticals, CAS-University of Tokyo Joint Laboratory of Structural Virology and Immunology, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, - - 2014
CD146 is a newly identified endothelial biomarker that has been implicated in angiogenesis. Though in vitro angiogenic function of CD146 has been extensively reported, in vivo evidence is still lacking. To address this issue, we generated endothelial-specific CD146 knockout (CD146(EC-KO)) mice using the Tg(Tek-cre) system. Surprisingly, these mice did not ...
Melancon Marites Pasuelo MP Departments of Interventional Radiology, ‡Cancer Systems Imaging, ∥Head and Neck Surgery, and ⊥Imaging Physics, The University of Texas MD Anderson Cancer Center , 1515 Holcombe Boulevard, Houston, Texas 77030, United - - 2014
The purpose of this study was to compare the binding affinity and selective targeting of aptamer- and antibody-coated hollow gold nanospheres (HAuNS) targeted to epidermal growth factor receptors (EGFR). EGFR-targeting aptamers were conjugated to HAuNS (apt-HAuNS) by attaching a thiol-terminated single-stranded DNA to the HAuNS and then adding the complementary ...
Nolte Froukje F Department of Biomedical Engineering and Physics, University of Amsterdam, Amsterdam, The - - 2014
Aims: It has been argued that hyperaemic microvascular resistance (HMR), defined as the ratio of mean distal coronary pressure to flow velocity, is overestimated in the presence of a coronary stenosis compared to actual microvascular resistance (MR), due to neglecting collateral flow. We aimed to test the hypothesis that HMR ...
Barragan Paul P Polyclinique Les Fleurs, Ollioules, - - 2014
Aims: The aim of this study was to characterise the coronary stent longitudinal resistance of new coronary stents under worst case clinical crossing simulated configurations. Methods and results: Six coronary balloon-expandable stents were evaluated using two different tests. The first was a direct parallel plates longitudinal crush resistance test: it ...
Qi Yuhua Y Key Laboratory of Fluorine Chemistry and Chemical Materials of Shandong Province, School of Chemistry and Chemical Engineering, University of Jinan, Jinan, 250022, People's Republic of China, - - 2014
The structures of unsaturated silylenoid HP=SiLiF were studied by density functional theory at the B3LYP/6-311+G(d,P) level. Four equilibrium structures, the three-membered ring (1), the four-membered ring (2), the "classical" silane (3), and the linear (4) structures, were located. Their energies are in the order of 4 > 3 > 1 > 2. To exploit the stability ...
Politzer Peter P Department of Chemistry, University of New Orleans, New Orleans, LA, 70148, USA, - - 2014
There is considerable evidence, which we discuss, indicating that compressibility and available free space in the crystal lattice are among the factors that govern the sensitivity of an explosive compound. Expanding and extending earlier work, we demonstrate, for 25 explosives, that there is an overall general tendency for greater impact ...
Steffen Philipp A PA Institute of Molecular Biotechnology (IMBA), Dr. Bohr-Gasse 3, 1030 Vienna, - - 2014
In any biological system with memory, the state of the system depends on its history. Epigenetic memory maintains gene expression states through cell generations without a change in DNA sequence and in the absence of initiating signals. It is immensely powerful in biological systems - it adds long-term stability to ...
Heidstra Renze R Plant Developmental Biology, Wageningen University and Research Centre, Droevendaalsesteeg 1, 6708 PB Wageningen, The - - 2014
The astonishingly long lives of plants and their regeneration capacity depend on the activity of plant stem cells. As in animals, stem cells reside in stem cell niches, which produce signals that regulate the balance between self-renewal and the generation of daughter cells that differentiate into new tissues. Plant stem ...
Ribeiro Expedito E EE Department of Interventional Cardiology, Heart Institute-InCor, University of São Paulo, São Paulo, - - 2014
Aims: The INSPIRON-I trial is a first-in-man evaluation of the safety and efficacy of the Inspiron drug-eluting stent, a sirolimus-eluting stent with abluminal biodegradable polymer coating and thin cobalt-chromium alloy. Methods and results: This is a randomised, multicentre comparison between Inspiron and a stent with the same metallic structure but ...
Morlacchi Stefano S Laboratory of Biological Structure Mechanics (LaBS), Department of Chemistry, Materials and Chemical Engineering "Giulio Natta", Politecnico di Milano, Milan, - - 2014
Aims: This study sought to investigate the possible influence of different bifurcation stenting techniques on stent deformation, physical stress, and drug elution using a virtual tool that includes structural, fluid dynamics and drug-eluting numerical models. Methods and results: A virtual bench test based on explicit dynamics modelling was used to ...
D'Ascenzo Fabrizio F Division of Cardiology, Department of Internal Medicine, Città Della Salute e Della Scienza, Turin, - - 2014
Aims: To establish the cardioprotective effect of remote ischaemic preconditioning (RIPC) in patients undergoing percutaneous coronary intervention (PCI). Methods and results: Pubmed (MEDLINE), Cochrane and Embase were systematically searched for randomised controlled trials of RIPC in patients undergoing PCI. Periprocedural myocardial infarction (PMI) was the primary endpoint (defined as troponin ...
Zhao Zhenguo Z School of Water Conservancy, North China University of Water Resources and Electric Power, Zhengzhou, China, - - 2014
With the fast advancement of the wireless communication technology and the widespread use of medical systems, the radio frequency identification (RFID) technology has been widely used in healthcare environments. As the first important protocol for ensuring secure communication in healthcare environment, the RFID authentication protocols derive more and more attentions. ...
Kalva Sukesh S Department of Bioinformatics, SRM University, SRM Nagar, Kattankulathur, 603 203, Kancheepuram District, Chennai, - - 2014
Matrix metalloproteinase-8 (MMP-8) is the key mediator in initiating type I collagen degradation and is associated with rheumatoid arthritis. In the present study, a pharmacophore hypothesis was developed based on selective non zinc binding inhibitors of MMP-8. The pharmacophore hypothesis was refined manually and validated by observing structures and the interactions ...
Nguyen Phuong T V PT School of Chemistry, University of Wollongong, Wollongong, 2522, - - 2014
The recent emergence and re-emergence of alphaviruses, in particular the chikungunya virus (CHIKV), in numerous countries has invoked a worldwide threat to human health, while simultaneously generating an economic burden on affected countries. There are currently no vaccines or effective drugs available for the treatment of the CHIKV, and with ...
Carter Natalie J NJ Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand, - - 2014
Degarelix (Firmagon(®); Gonax(®)) is a gonadotropin-releasing hormone receptor antagonist that is approved for the treatment of advanced (hormone-dependent) prostate cancer in the US and EU and the treatment of prostate cancer in Japan. In a pivotal randomized, controlled, 12-month phase III study, degarelix (initial subcutaneous dose of 240 mg followed by ...
Rozniecka Ewa E Institute of Physical Chemistry, Polish Academy of Sciences, ul. Kasprzaka 44/52, 01-224 Warszawa, Poland. martinj@ichf.edu.pl - - 2014
There is a continuous need for the construction of detection systems in microfluidic devices. In particular, electrochemical detection allows the separation of signals from the analyte and interfering substances in the potential domain. Here, a simple microfluidic device for the sensitive and selective determination of dopamine in the presence of ...
Ahmed Sohail S Department of Chemistry, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia. - - 2014
An octa-nuclear heterobimetallic complex [Y2Cu6Cl0.7(dmae)6(OAc)7.3(OH)4(H2O)2]·3H2O·0.3CH3C6H5 (dmae = dimethylaminoethanoate; OAc = acetato) was synthesized, characterized by melting point analysis, elemental analysis, FT-IR, and single crystal X-ray diffraction analysis and implemented at 600 °C under an oxygen atmosphere for the deposition of Y2CuO4-5CuO composite thin films by aerosol assisted chemical vapor deposition ...
Spitznagel Frank A FA Department of Prosthodontics, School of Dentistry, Albert-Ludwigs University, Freiburg, - - 2014
Resin bonding is essential for clinical longevity of indirect restorations. Especially in light of the increasing popularity of computer-aided design/computer-aided manufacturing-fabricated indirect restorations, there is a need to assess optimal bonding protocols for new ceramic/polymer materials and indirect composites. The aim of this article was to review and assess the ...
Umansky Viktor V Skin Cancer Unit (G300), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany, - - 2014
Malignant melanoma is characterized by the development of chronic inflammation in the tumor microenvironment, which leads to a strong immunosuppression associated with a rapid tumor progression. Adenosine is considered as one of the main immunosuppressive factors in the tumor environment. It is produced via enzymatic hydrolysis of extracellular ATP by ...
Hu Yinin Y Department of Surgery/Division of Surgical Oncology, University of Virginia Health System, PO Box 800679, Charlottesville, VA, 22908-0679, USA, - - 2014
Immunization with a combination melanoma helper peptide (6MHP) vaccine has been shown to induce CD4(+) T cell responses, which are associated with patient survival. In the present study, we define the relative immunogenicity and HLA allele promiscuity of individual helper peptides and identify helper peptide-mediated augmentation of specific CD8(+) T ...
Koga Kaori K Department of Obstetrics and Gynecology, The University of Tokyo, Tokyo, - - 2014
Toll-like receptors (TLRs) form the major family of pattern recognition receptors (PRRs) that are involved in innate immunity. Innate immune responses against microorganisms at the maternal-fetal interface may have a significant impact on the success of pregnancy, as intrauterine infections have been shown to be strongly associated with certain complications ...
Bubach Débora D Laboratorio de Análisis por Activación Neutrónica, Centro Atómico Bariloche, CNEA, Av. Bustillo km 9.5, 8400, Bariloche, Argentina, - - 2014
The atmospheric transport of volcanic products are subject to several variables, mainly the height of the eruption column and wind direction, thus elements associated with the ashes are deposited in major or lesser degree depending on variables as latitude, wind and humidity. The lichens are able to reflect the atmospheric ...
Mohee K K Division of Cardiovascular & Diabetes Research, Leeds Multidisciplinary Cardiovascular Research Centre, University of Leeds, Leeds, - - 2014
Cardioprotective drug regimens improve outcomes in patients with stable coronary artery disease. Revascularization is recommended for the persistence of symptoms despite optimal medical therapy (OMT) or in patients likely to derive prognostic benefit. Our objective is to comment on recent evidence that initiation of OMT is suboptimal in patients undergoing ...
Kaku Yoshiko Y Division of Bioinformation, Department of Physiology, Hyogo College of Medicine, 1-1 Mukogawa-cho, 663-8501, Nishinomiya, - - 2014
The newly synthesized naftopidil analogue HUHS1015 reduced cell viability in malignant pleural mesothelioma cell lines such as MSTO-211H, NCI-H28, NCI-H2052, and NCI-H2452 cells, with the potential greater than that for the anticancer drugs paclitaxel or cisplatin at higher concentrations more than 30 μM. HUHS1015 induced both necrosis and apoptosis of ...
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