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Xu Tao T Department of Chemistry and Biochemistry, University of Texas at Austin, 1 University Station A5300, Austin, TX, 78712-0165, - - 2014
With the advent of new synthetic methodologies, carbon-carbon bond (C-C) activation strategies have uncovered not only new fundamental reactivity but also the potential for use as a highly efficient synthetic protocol. This chapter specifically discusses the use of four-membered ketone-based starting materials for C-C activation initiated transformations using a variety ...
Gryndler Milan M Faculty of Sciences, J.E. Purkinje University, České mládeže 8, Ústí nad Labem, 400 96, Czech Republic, - - 2014
Mycorrhizal fungi provide direct and functional interconnection of soil environment with their host plant roots. Colonization of non-host plants have occasionally been described, but its intensity and functional significance in complex plant communities remain generally unknown. Here, the abundance of ectomycorrhizal fungus Tuber aestivum was measured in the roots of ...
Ahn Youngbeom Y National Center for Toxicological Research, Division of Microbiology, US Food and Drug Administration, 3900 NCTR Road, Jefferson, AR, 72079-9502, USA, - - 2014
Burkholderia cepacia complex (BCC) presence has been the cause of recalls of both sterile and non-sterile pharmaceutical products since these opportunistic pathogens have been implicated to cause infections to susceptible individuals. BCC are ubiquitous in nature, but in pharmaceutical settings the most common source is contaminated water systems. Some strains ...
Liao Zheng-Gen ZG Key Laboratory of Modern Preparation of TCM of Ministry of Education, Jiangxi University of TCM, Nanchang, 330004, - - 2014
The root of Angelica dahurica (Radix Angelicae Dahuricae, RAD), which contains coumarins and volatile oil as its main classes of active components, is often given in conjunction with Pueraria root (Radix Puerariae, RP), which contains the phytoestrogen puerarin. The two herbs are considered to be compatible 'herb-pairs' in traditional Chinese ...
Wang Peng P Department of Chemistry & Biochemistry, University of Delaware, Newark, DE 19716, USA. - - 2014
A series of five-coordinate M(II)-semiquinonate (M = Fe, Mn, Co) complexes were synthesized and characterized, including the first example of a mononuclear Fe(II)-semiquinonate. Intermediates were observed in the reactions of M(II)-phenSQ (M = Fe, Co) with O2. Evidence for the relevance of these intermediates to the intradiol catechol dioxygenases was ...
Wan Lian - - 2014
The electrochemical performance of the pseudocapacitive materials is seriously limited by poor electron and ions transport. Herein, an advanced integrated electrode has been designed by growing the pseudocapacitive materials, including CoxNi1-x(OH)2, CoxNi1-xO, and (CoxNi1-x)9S8, on a three-dimensional hollow carbon nanorod arrays (HCNA) scaffold. The HCNA scaffold not only can provide ...
Chen Zhu Z Center on the Early Life Origins of Disease, Department of Population, Family and Reproductive Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, - - 2014
There is an emerging hypothesis that exposure to cadmium (Cd), mercury (Hg), lead (Pb), and selenium (Se) in utero and early childhood could have long-term health consequences. However, there are sparse data on early life exposures to these elements in US populations, particularly in urban minority samples. This study measured ...
Raposo Catarina C Department of Neurobiology, Weizmann Institute of Science, Rehovot, - - 2014
Inadequate axonal regeneration is a common phenomenon occurring following acute injury to the central nervous system (CNS), and is often associated with permanent neurological deficits. The injured axons attempting to regenerate face the inhospitable environment of the CNS scar, which can hinder axonal growth and sprouting. In addition, in response ...
Jansook Phatsawee P Faculty of Pharmaceutical Sciences, Chulalongkorn University , Bangkok , Thailand - - 2014
Abstract Aqueous nanoparticulated eye drop formulations based on γ-cyclodextrin (γCD) complexes were developed and tested in vitro. Three antihypertensive drugs, i.e. enalapril maleate, irbesartan and verapamil HCl, that have been shown to possess IOP-lowering activity were selected for this study. All three drugs displayed Bs-type phase-solubility diagrams in aqueous γCD ...
Malewar Nikhil N Lupin Ltd. (Research Park) , Nande Village, Mulshi Taluka, Pune, Mahrarashtra , India - - 2014
Abstract Context: Venlafaxine Hydrochloride (VH) is a highly soluble and highly permeable antidepressant compound. Thus controlling VH release from tablet dosage form over a prolonged period is a challenge. Objective: The objective of this work was to study the effect of various barrier layer formulation compositions, its orientations and manufacturing ...
Noonan Curtis W CW Center for Environmental Health Sciences, Department of Biomedical Sciences, University of Montana, Missoula, Montana, - - 2014
Libby, MT, USA, was the home to workers at a historical vermiculite mining facility and served as the processing and distribution center for this industrial product that was contaminated with amphibole asbestos. Several pathways of environmental asbestos exposure to the general population have been identified. The local clinic and health ...
O Connor Karen K University College Dublin, Dublin, Ireland, - - 2014
This tudy aims to assess and compare objective and subjective scores of empathy in final-year medical students by using firstly a validated student self-assessment just prior to the psychiatry objective structured clinical examination (OSCE), and then comparing this to clinical examiner's and simulated patient's (SP's) assessments of empathy of students ...
Qian Hua H ExxonMobil Biomedical Sciences, Annandale, New Jersey, - - 2014
As regulatory initiatives increasingly call for an understanding of the cumulative risks from chemical mixtures, evaluating exposure data from large biomonitoring programs, which may inform these cumulative risk assessments, will improve the understanding of occurrence and patterns of coexposures. Here we have analyzed the urinary metabolite data for six phthalates ...
Hayden Luke L Evolutionary Developmental Biology Laboratory, Zoology, School of Natural Sciences, National University of Ireland, Galway, - - 2014
The genes of the Wnt family play important roles in the development of many animals. In the arthropods, these genes are known to have multiple functions, including roles in posterior development and segmentation. Despite this, secondary loss of Wnt genes is common among the Arthropoda. Unlike many arthropods, Strigamia maritima, ...
van Veluw Susanne J SJ Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The - - 2014
In patients with spontaneous intracerebral hemorrhage (ICH) coexisting abnormalities on brain imaging can provide clues on the etiology of the underlying small vessel disease. We examined cortical cerebral microinfarcts as a novel marker of coexistent vascular damage in ICH. Twelve patients with spontaneous ICH and 15 controls underwent 7Tesla magnetic ...
Morris S S Department of Applied Health Research, University College - - 2014
A recent Cochrane review suggested that laparoscopic cholecystectomy carried out early following mild gallstone pancreatitis was safe. This study compared the cost-effectiveness of laparoscopic cholecystectomy performed within 3 days of admission, during the same admission but after more than 3 days, or electively in a subsequent admission. A model-based cost-utility analysis was ...
Menon Rajiv G RG Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, - - 2014
Magnetic resonance (MR)-based oxygen extraction fraction (OEF) measurement techniques that use blood oxygen level-dependent (BOLD)-based approaches require the measurement of the R2' decay rate and deoxygenated blood volume to derive the local oxygen saturation in vivo. We describe here a novel approach to measure OEF using rapid local frequency mapping. ...
Plaat Boudewijn E C BE Department of Otorhinolaryngology, Head and Neck Surgery, University of Groningen, University Medical Center Groningen, P.O. Box 30001, 9700 RB, Groningen, The Netherlands, - - 2014
Endoscopic sheaths covering the laryngoscope are advised to prevent cross contamination, but might hamper visualization as the most important tool in the diagnostic approach of laryngeal disease. We evaluated whether endoscopic sheaths change image quality and diagnostic accuracy of flexible distal chip laryngoscopy (DCL) and flexible fiberoptic laryngoscopy (FOL). Twelve ...
Slade Eric P EP U.S. Department of Veterans Affairs, VA Capitol Healthcare Network Mental Illness Research, Education, and Clinical Center, 10 N. Greene Street, Baltimore, MD, 21201, USA, - - 2014
This study examines general hospitals' adjustments in psychiatric bed utilization practices in response to increases in psychiatric inpatient admissions. Using panel data from 439 hospitals, monthly observations (N = 7,831) between 2007 and 2010 on psychiatric admissions, psychiatric bed occupancy rates, and average length-of-stay were created for psychiatric inpatients. In fixed-effects regressions, ...
Lee Aram - - 2014
microRNAs (miRNAs) are a class of small, non-coding RNAs that play critical posttranscriptional regulatory roles typically through targeting of the 3'-untranslated region of messenger RNA (mRNA). Mature miRNAs are known to be involved in global cellular processes, such as differentiation, proliferation, apoptosis, and organogenesis, due to their capacity to target ...
Grasso M M Otorhinolaryngology Section, Department of Sensorial Organs, "Sapienza" University of Rome, Rome, Italy, - - 2014
Recurrent respiratory papillomatosis is a viral-induced disease, associated with exophytic epithelial lesions affecting the upper airways. Problem of treatment is the high recurrence of papilloma growth after surgical removal; therefore, adjuvant therapy schemes have been established. We used cidofovir, 7.5 mg/ml, in adjuvant therapy in the past years. Out of 31 ...
Lee Sojung S Division of Weight Management and Wellness, Children's Hospital of Pittsburgh, Pittsburgh, PA, - - 2014
Non-alcoholic fatty liver disease (NAFLD) is a comorbidity of childhood obesity. We examined whole-body substrate metabolism and metabolic characteristics in obese adolescents with vs. without NAFLD. Twelve obese (BMI ≥ 95th percentile) adolescents with and without NAFLD [intrahepatic triglyceride (IHTG) ≥5.0% vs. <5.0%] were pair-matched for race, gender, age and % body ...
Shin Jung Hoon - - 2014
CD1 molecules belong to non-polymorphic MHC class I-like proteins and present lipid antigens to T cells. Five different CD1 genes (CD1a~e) have been identified and classified into two groups. Group 1 include CD1a~c and present pathogenic lipid antigens to αβT cells reminiscence of peptide antigen presentation by MHC-I molecules. CD1d ...
Yang Fan F Department of Obstetrics and Gynecology, Ningxia People's Hospital, No.301 North Zhengyuan Street, Jinfeng District, Yinchuan City, 750002,Ningxia Province, - - 2014
This study was to investigate the role of Fas in the development of Cisplatin-resistant ovarian cancer. On the cellular level, Fas expression was significantly reduced in Cisplatin-resistant A2780/CP cells compared with A2780 cells. Fas silence with siRNA would promote tumor cell lines proliferation, facilitate tumor cell cycle transition of G1/S, ...
Licciardello Alessio A Division of General Surgery, Civil Hospital of Lentini, C/da Colle Roggio, 96016, Lentini, SR, Italy, - - 2014
Internal hernias account for 0.2-0.9 % of all small bowel obstructions and are associated with a mortality rate of 50 % when strangulation is present. Congenital mesocolic hernias, traditionally called paraduodenal hernias, caused by an abnormal rotation of the primitive midgut, are the most common type of internal hernia. They can be ...
Raouf H E HE Department of Microbiology and Immunology, Faculty of Pharmacy, Modern Sciences and Arts University, Giza, - - 2014
Occult hepatitis B infection is characterized by the presence of hepatitis B virus (HBV) DNA in the serum in the absence of hepatitis B surface antigen (HBsAg). Prevalence of hepatitis C virus (HCV) infections in Egypt is among the highest in the world. In this study, we aim at analysing ...
Gasinska Anna A Department of Applied Radiobiology, Oncology Center, Maria Sklodowska-Curie Memorial Institute, Garncarska 11, 31-115, Cracow, Poland, - - 2014
Prognostic value of pretreatment expression of proteins in rectal cancer for early pathological tumor response (pTR), clinical tumor response (CTR) to preoperative radiotherapy (RT), and the potential difference between these parameters depending on patient gender is not established. One hundred eleven patients were treated with short preoperative course of RT ...
Cabrera-Andrade A A Biomedical Research Institute, School of Health Science, Universidad de las Américas, Quito, - - 2014
Helicobacter pylori (Hp) has a worldwide distribution showing its higher prevalence of infection in developing countries. Toll-like receptors (TLRs) and C-type lectin receptors (CLRs) are proteins that recognize pathogen-associated molecular patterns (PAMPs) and initiate an innate immune response by promoting growth and differentiation of specialized hematopoietic cells for host defense. ...
Savi Andrea A Brescia, - - 2014
The treatment of a diffuse and severe case of amelogenesis imperfecta represents a challenge for the dental team and in particular for the dentist who perform the prosthetic restorations. The enamel alterations, which are characteristic of the disease, determine different problems that need to be carefully planned and solved before ...
Aungst Stephanie L SL Department of Anesthesiology, Shock, Trauma, and Anesthesiology Research (STAR) Center, University of Maryland School of Medicine, Heath Sciences Facility 2 (HSF2), Baltimore, Maryland, - - 2014
Repeated mild traumatic brain injury (mTBI) can cause sustained cognitive and psychiatric changes, as well as neurodegeneration, but the underlying mechanisms remain unclear. We examined histologic, neurophysiological, and cognitive changes after single or repeated (three injuries) mTBI using the rat lateral fluid percussion (LFP) model. Repeated mTBI caused substantial neuronal ...
Hempel Casper C Centre for Medical Parasitology, Department of Clinical Microbiology, Copenhagen University Hospital, Copenhagen, - - 2014
We hypothesized that the glycocalyx, which is important for endothelial integrity, is lost in severe malaria. C57BL/6 mice were infected with Plasmodium berghei ANKA, resulting in cerebral malaria, or P. chabaudi AS, resulting in uncomplicated malaria. We visualized the glycocalyx with transmission electron microscopy and measured circulating glycosaminoglycans by dot ...
Li Jinrang J Department of Otorhinolaryngology Head & Neck Surgery, Navy General Hospital, Beijing, 100048, China, - - 2014
The grading system of the severity of obstructive sleep apnea hypopnea syndrome (OSAHS) used presently showed that the severe OSAHS had an extensive range of apnea hypopnea index (AHI) (≥30, even over 100). So this grading system is not rational. From Jan 1999 to June 2011, there were 2,618 patients ...
Pathak Rakesh K RK NanoTherapeutics Research Laboratory, Department of Chemistry, University of Georgia, Athens, GA 30602 (USA), Fax: (+1) 706-542-9454 - - 2014
The ability to rationally design and construct a platform technology to develop new platinum(IV) [Pt(IV) ] prodrugs with functionalities for installation of targeting moieties, delivery systems, fluorescent reporters from a single precursor with the ability to release biologically active cisplatin by using well-defined chemistry is critical for discovering new platinum-based ...
Rana Kuldeep - - 2014
The electrodes in lithium-ion batteries (LIBs) are typically films that are arranged on metal foil current collectors with a thickness of several tens of µm. Here, we report on the preparation of a thick free-standing graphene film synthesized by CVD as an alternative to Cu foil as an anode current ...
Ramos José M JM Department of Internal Medicine, Servicio de Medicina Interna, Hospital General Universitario de Alicante, C/Pintor Baeza, 12, 03010, Alicante, Spain, - - 2014
Older patients referred for further investigation of pancytopenia is common in internal medicine and geriatric clinics and it is important to consider a wide range of underlying diagnoses. We present an unusual case of febrile pancytopenia in a nonagenarian who was diagnosed with visceral leishmaniasis. This is a rare and ...
He Chun-Yan CY Department of Pathology, Beijing Tongren Hospital, Capital Medical University, No.1, Dongjiaominxiang, Street. Dongcheng District, Beijing, 100730, - - 2014
Inflammatory myofibroblastic tumor (IMT) is rare in nasal cavity and paranasal sinus. The aim of this study was to describe the clinicopathological features of sinonasal IMT and analyze the relationship between the clinicopathological features and the prognosis. A retrospective study of 25 IMT patients between 2001 and 2012 was performed. ...
Pan Lei L School of Chemistry and Chemical Engineering, Shanghai Jiaotong University, Shanghai 200240, China. - - 2014
Yolk-shell structured Si-C nanocomposites are easily synthesized by using a new method based on alkaline etching technology, and exhibit high specific capacity, good cycling stability and rate performance as anodes for lithium-ion batteries.
Lindeboom Erik J EJ Research School of Chemistry, Australian National University Canberra, Canberra, ACT 0200 - - 2014
The first four-fold cross coupling reaction involving alkenic partners leads to the title hydrocarbon on multi-gram scale in one step from commercially available precursors. In stark contrast to its close structural relatives, tetravinylethylene is a remarkably robust, bench-stable compound. The π-bond rich hydrocarbon is shown to undergo one-pot sequences of ...
Ipuy Martin M Laboratoire de Chimie de l'ENS de Lyon, CNRS UMR 5182, Ecole Normale Supérieure de Lyon, Université Lyon I, 46 allée d'Italie, 69364 Lyon cedex 07, France. - - 2014
A family of fluorescent push-pull pH-responsive probes based on 2-dicyanomethylidene-3-cyano-4,5,5-trimethyl-2,5-dihydrofuran as a strong electron acceptor group is described. Small structural variations allow obtaining pKa ranging from 4.8 to 8.6, underlining the role of the substituent in modulating the acidic properties. Remarkable changes in the optical properties (in particular the fluorescence ...
Stucky C-C H CC Department of General Surgery, Mayo Clinic Arizona, 5777 E. Mayo Boulevard, Phoenix, AZ, 85054, - - 2014
Previous reports document the safety of open inguinal herniorrhaphy in patients on chronic warfarin therapy; however, the practice remains controversial. This study is a 10-year update of our experience. A retrospective review of 1,839 consecutive patients undergoing open inguinal hernia repair was conducted from 2000 to 2010. All patients on ...
Hammer Christian C Department of Human Molecular Genetics, University of Heidelberg, Heidelberg, - - 2014
Copy number variants (CNVs) have been shown to affect susceptibility for neuropsychiatric disorders. To date, studies implicating the serotonergic system in complex conditions have just focused on single nucleotide polymorphisms (SNPs). We therefore sought to identify novel common genetic copy number polymorphisms affecting genes of the serotonergic system, and to ...
Irar Sami S Servicio de Proteómica y Metabolómica, CRAG - Centre de Recerca en Agrigenòmica - CSIC IRTA UAB UB, Campus UAB, Edifici CRAG, Bellaterra (Cerdenyola del Valles), 08193, Barcelona, - - 2014
Drought is considered the more harmful abiotic stress resulting in crops yield loss. Legumes in symbiosis with rhizobia are able to fix atmospheric nitrogen. Biological nitrogen fixation (SNF) is a very sensitive process to drought and limits legumes agricultural productivity. Several factors are known to regulate SNF including oxygen availability ...
Vargas Hebert Alberto HA Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, - - 2014
The high incidence of prostate cancer, coupled with excellent prostate cancer control rates, has resulted in growing interest in nononcological survivorship issues such as sexual function. Multiparametric magnetic resonance imaging (MRI) is increasingly being performed for local staging of prostate cancer, and due to the close anatomical relationship to the ...
Khampieng Thitikan T a Center of Excellence on Petrochemical and Materials Technology (PETROMAT), The Petroleum Petrochemical College, Chulalongkorn University , Bangkok 10330 , - - 2014
Silver nanoparticle (nAg)-embedded poly(vinyl pyrrolidone) (PVP) hydrogels, to be used as antibacterial wound dressings, were prepared by γ-irradiation at various doses: 25, 35, and 45 kGy. The formation and characteristics of the silver nanoparticles were investigated with a UV-vis spectrophotometer, transmission electron microscopy, and scanning electron microscopy with energy-dispersive X-ray. The ...
Yazıcıoğlu Oktay O Department of Restorative Dentistry, Faculty of Dentistry, Istanbul University, Istanbul, - - 2014
A talon cusp is a morphologically well-delineated accessory cusp. This case report discusses the unusual appearance of a talon cusp on the facial surface of the maxillary right permanent central incisor, which was conservatively treated and followed up for a period of 1 year. A 21-year-old female was referred for ...
Pua Yong-Hao YH Department of Physiotherapy, Singapore General Hospital, Outram Road, Singapore, 169608, Singapore, - - 2014
Contrary to the ample data available regarding the functional significance of isokinetic knee strength in patients with anterior cruciate ligament deficiency (ACLD), much less is known about the functional significance of isokinetic knee steadiness. This cross-sectional study aimed to evaluate, in patients with ACLD, the independent impact of isokinetic quadriceps ...
Frosch Stephan S Department of Trauma Surgery, Plastic and Reconstructive Surgery, University Medicine Göttingen, Robert Koch Straße 40, 37075, Göttingen, Germany, - - 2014
In rotator cuff repair, strong and long-lasting suturing techniques that do not require additional implants are needed. This study examines the ultimate load to failure and the Young's modulus at the suture-tendon interface for a novel single-loop knot stitch and double-loop knot stitch. These values are compared to those of ...
Takenaka Shota S Japan Community Health care Organization Osaka Hospital, 4-2-78 Fukushima, Osaka, 553-0003, Japan, - - 2014
Investigation of preoperative manifestations of thoracic myelopathy in a large population has not been reported. The aim of this study was to identify symptoms specific to anatomical pathology or compressed segments in thoracic myelopathy through investigation of preoperative manifestations. Subjects were 205 patients [143 men, 62 women; mean age, 62.2 ...
Sarzaeem M M MM Department of Orthopedic Surgery, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran, - - 2014
The gold standard in ACL reconstructions has been the bone-patellar tendon-bone autograft fixed with interference screws. This prospective, randomized clinical trial aimed to compare two methods of fixation for BPTB grafts: press-fit fixation vs. interference screw, over a 12-month follow-up interval. 158 patients with an average age of 29.8 years, between ...
Roh Young Hak YH Department of Orthopaedic Surgery, Gil Medical Center, Gachon University School of Medicine, Inchon, - - 2014
Several radiographic carpal alignment indices are used to evaluate the deformities of scaphoid fractures. The purpose of this study was to determine the reliabilities and validities of radiographic carpal alignment indices commonly used to evaluate deformities of scaphoid fractures. Thirty-six patients with a scaphoid fracture were evaluated. Five carpal alignment ...
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