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Results 301 - 350 of 2047
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Salilew-Wondim D - - 2013
Follicular development is a result of complex hormonal and biochemical synergies that could be activated or deactivated in a spatiotemporal manner in oocytes and surrounding cells including theca, granulosa, and cumulus cells. The microRNA (miRNA), 19 to 22 nucleotides noncoding RNA, are one of the molecular cues that could play ...
Ortega M S - - 2013
The objective was to identify patterns of expression during the pre-implantation period of several genes associated with genetic variation in fertility (CWC15) or development to the blastocyst stage (C1QB, MON1B, PARM1, PCCB, PMM2, TBC1D24, and WBP1). These genes are involved in cellular processes such as mRNA splicing, immune protection, fatty ...
Berté L - - 2013
Bovine growth hormone (bGH) has been used to improve the results for in vitro production of bovine embryos. Inclusion of bGH in the maturation medium increases both rate of cleavage and frequency of blastocyst development. Thus, the purpose of the present study was to evaluate the effect of recombinant bovine ...
Reynaud K - - 2013
In the canine species, assisted reproductive technologies, especially in vitro maturation (IVM) and IVF, are still ineffective. The main limiting factor remains the immaturity of the oocytes collected from anestrus ovaries. The ability of an oocyte to reach the MII stage in vitro is linked to the diameter of its ...
Kohn E C - - 2013
In the era of morphologic diagnostics, any epithelial tumor on or involving the ovaries was presumed to come from and be strictly of ovarian origin, apart from the rare but clearly metastatic tumors. Thus, many women who might have had small fallopian tube primary cancers that rapidly extended on to ...
Friedlander M L - - 2013
There is general acceptance of the importance of incorporating patient-reported outcome (PRO) measures including health-related quality of life (HRQOL) into clinical trials, and there are now a number of guidance documents available on how to use PRO's for regulatory authorities and in comparative effectiveness research. The methods used to collect, ...
Lillington Linda - - 2013
High-quality nursing care is not delivered consistently to the millions of Americans treated for invasive cancer in the United States. As part of its quality initiative, the Oncology Nursing Society (ONS) developed and tested nursing-sensitive quality measures for breast cancer care. Findings from the pilot testing suggested significant knowledge and ...
Sargent Charli - - 2013
Altitude training is used by elite athletes to improve sports performance, but it may also disrupt sleep. The aim of this study was to examine the effects of 2 weeks at high altitude on the sleep of young elite athletes. Participants (n=10) were members of the Australian under-17 soccer team ...
Park Ki-Eun - - 2013
The establishment of embryonic stem cells (ESCs) and gene targeting technologies in mice has revolutionised the field of genetics. The relative ease with which genes can be knocked out, and exogenous sequences introduced, has allowed the mouse to become the prime model for deciphering the genetic code. Not surprisingly, the ...
Park E J - - 2013
The efficiency of animal cloning through somatic cell nuclear transfer (SCNT) technology is affected by numerous factors such as oocyte quality and donor cell type. Among the factors, oocyte quality can be enhanced by identification and selection of developmentally competent oocytes before in vitro maturation (IVM). Morphological criteria following homogeneous ...
Ramos R D S - - 2013
Acknowledging that the local oxidative profile (pro or antioxidant) may influence the control of very specific mechanisms such as intracellular signalling as well as the unspecific damage caused by oxidative stress, it is proposed that the balance between reducing and oxidative activities of the uterine environment (i.e. the REDOX profile) ...
Parra-Forero L Y - - 2013
The follicular fluid manage and keeps the nutrition of the oocyte and granulosa cell, which are develop inside this liquid. As well this fluid contains growth hormones, growth factors, and some micro-minerals as zinc (Zn). Resources report that Zn could avoid the earlier meiotic detention of the gametes, strengthen the ...
Alsaleh A - - 2013
Coxiella burnetii, an obligate intracellular bacterium of worldwide distribution, is responsible for Q fever. Domestic ruminants are the main sources of infection for humans. In cattle, infection is frequently asymptomatic, but it may cause abortion, reproductive failure (metritis, placentitis, and infertility), and economic losses. A previous study in goats showed ...
Robertson Suzanne L - - 2013
Many factors influencing disease transmission vary throughout and across populations. For diseases spread through multiple transmission pathways, sources of variation may affect each transmission pathway differently. In this paper we consider a disease that can be spread via direct and indirect transmission, such as the waterborne disease cholera. Specifically, we ...
Hwang K-A - - 2013
It has been shown that oestrogen (E2) up-regulated the expression of components of insulin-like growth factor-1 (IGF-1) signaling pathway and induced the downstream of mitogenic signaling cascades via phosphorylation of insulin receptor substrate-1 (IRS-1). An interaction between oestrogen receptor (ER) and IGF-1 receptor (IGF-1R) signaling pathway plays an important role ...
Imai K - - 2013
Recently, we reported on a promising system for selecting healthy IVF embryos in cattle using kinetics of early embryo development and oxygen consumption of blastocyst [Sugimura et al. 2012 PLoS ONE 7, e36627]. The present study was conducted to examine the differences in embryo quality of bovine blastocysts obtained after ...
Carnevale E M - - 2013
Intracytoplasmic sperm injection (ICSI) is used to produce offspring from stallions with poor quality or limited availability of semen. Embryos produced by ICSI can be cultured to a stage of development suitable for nonsurgical transfer into recipient uteri. However, use of a recipient is expensive, and transfer of an ICSI-produced ...
Nielsen Tore - - 2013
Certain method of loci (MoL) prerequisites - familiar, coherently ordered locations - should appear during dreaming if the latter is, in fact, elaborative memory encoding as hypothesized by Llewellyn. A review of the literature suggests that dreamed locations are neither familiar nor coherently ordered and thus unsuitable for facilitating memory in this sense. This ...
Wright Rex A - - 2013
We address points of confusion pertaining to interrelations among and roles of core constructs involved in the production of performance outcomes. We do so informed by the body of work derived from Brehm's seminal motivation intensity theory - in particular an elaboration from the theory concerned with fatigue influence on effort and ...
Esper Peg - - 2013
More cancer therapies are being administered via an oral route. This paradigm shift in providing cancer treatment has been met with both excitement and significant challenges for oncology practitioners. Multiple factors can impact the ability for patients to initiate and stay on oral cancer therapy. A major factor in patient ...
Khokhar Nasir - - 2013
Objective: To treat decompensated hepatitis C patient with interferon, ribavirin and amantidine to ascertain the sustained viral response. Study Design: Descriptive study. Place and Duration of Study: Shifa International Hospital, Islamabad, from January 2007 to January 2012. Methodology: HCV PCR patients with decompensated hepatitis C, who had developed a complication ...
Draelos Zoe - - 2013
Even facial pigmentation is considered a universal sign of youth and beauty in all cultures and at all ages in both men and women. The recent FDA concern about the safety of topical hydroquinone has provided the impetus for research into new pigment lightening alternatives in the cosmetic OTC market. ...
Faiss Raphaël - - 2013
Over the past two decades, intermittent hypoxic training (IHT), that is, a method where athletes live at or near sea level but train under hypoxic conditions, has gained unprecedented popularity. By adding the stress of hypoxia during 'aerobic' or 'anaerobic' interval training, it is believed that IHT would potentiate greater ...
Lai Chung-Sheng - - 2013
On the basis of the close anatomical interdigitation between the longitudinal-oriented frontalis muscle and the horizontal-oriented orbicularis oculi muscle (OOM), frontalis OOM (FOOM) flap was developed to treat blepharoptosis. Retrospective study during an 11-year period, 66 patients with 81 poor levator function ptotic eyelids accepted FOOM flap shortening (65 lids; ...
Oksenberg Jorge R - - 2013
A wealth of data confirms that genetic variation is an important determinant of multiple sclerosis (MS) risk. Population, family and molecular studies provide strong empirical support for a polygenic model of inheritance, driven primarily by allelic variants relatively common in the general population. The major histocompatibility complex (MHC) in chromosome ...
Tarini Beth A BA FAAP, Child Health Evaluation and Research Unit, University of Michigan, 300 North Ingalls St, Room 6D19, Ann Arbor, MI 48109-5456. - - 2013
The family history has been called the first genetic test; it was a core element of primary care long before the current wave of genetics technologies and services became clinically relevant. Risk assessment based on family history allows providers to personalize and prioritize health messages, shifts the focus of health ...
Uojima Haruki - - 2013
We report two cases of ruptured pyogenic liver abscesses where one patient survived and the other died. We suspected that infection with gas-producing bacteria was the cause of the latter outcome, and we reviewed 47 case reports of ruptured pyogenic liver abscesses. Of the 47 cases, we determined that 77.6% ...
Ideta A - - 2013
Recently, we developed a medium that enabled bovine embryos to be held for up to 7 days at 4°C (Tsuchiya et al. 2014 IETS meeting). To be of practical value, mammalian embryo preservation at hypothermic temperatures must be able to maintain viability for periods longer than 7 days. Antifreeze proteins ...
Kim E - - 2013
The objective was to investigate the effects of zinc (Zn) insufficiency during in vitro maturation (IVM) of porcine oocytes. Zinc insufficiency was induced by treatment of Zn chelator, N,N,N',N'-tetrakis-(2-pyridylmethyl)-ethylendiamine (TPEN). In experiment 1, we investigated the effect of duration of Zn insufficiency in IVM on oocytes maturation and subsequent embryonic ...
Urrego R - - 2013
The ability of bovine embryos to develop to the blastocyst stage, to implant, and to generate healthy offspring, depends greatly on the oocyte contribution. Oocyte competence is attributed to its close communication with the follicular environment and to its capacity to synthesise and store great amounts of mRNA. Higher developmental ...
Hirabayashi M - - 2013
Rat embryonic stem (ES) cell lines can be established in culture medium containing inhibitors for glycogen synthase kinase 3 (GSK3) and mitogen-activated protein kinase (MEK). We confirmed reproducibility of the 2i culture system in establishing rat ES cell lines (Hirabayashi et al. 2010 Mol. Reprod. Dev. 77, 94) and the ...
Charney Evan - - 2013
Kurzban et al. argue that the experiences of "effort," "boredom," and "fatigue" are indications that the costs of a task outweigh its benefits. Reducing the costs of tasks to "opportunity costs" has the effect of rendering tasks costless and of denying that they can be inherently boring or tedious, something ...
Ko Chang-Nam - - 2013
Chunghyuldan (CHD), a combinatorial drug that has anti-hyperlipidemic and antiinflammatory activities, has been shown to reduce infarct volume in a focal ischemia-reperfusion rat model. To explore the molecular basis of CHD's neuroprotective effect, we examined whether CHD shows a cell-protective activity and has a regulatory effect on Bax and/or B-cell ...
Jackson Carlayne E - - 2013
Myopathies are a heterogeneous group of disorders that can be challenging to diagnose. The purpose of this review is to provide a diagnostic approach based predominantly on the clinical history and neurologic examination. Laboratory testing that can subsequently be used to confirm the suspected diagnosis based on this pattern recognition ...
Roach Gregory D - - 2013
Altitude exposure causes acute sleep disruption in non-athletes, but little is known about its effects in elite athletes. The aim of this study was to examine the effects of altitude on two groups of elite athletes, that is, sea-level natives and high-altitude natives. Sea-level natives were members of the Australian ...
Ou Kuang-Ling - - 2013
Microsurgical free flap has gained the popularity over pedicle flap nowadays in the reconstruction of head and neck. However, pedicled flaps remain a promising alternative and have a remarkable position in selected patients. This review study aimed to determine the reliability and versatility of the lower trapezius musculocutaneous flap for ...
Miller Phil E - - 2013
The deployment experiences of military mental health providers (MMHP) since September 2001 have been largely unexamined. MMHP are an integral part to the military health system and play a key role in maintaining a fit fighting force. MMHP deploy and are expected to help others manage their deployment experiences while ...
Said Maria A - - 2013
Severe adverse events, including eczema vaccinatum (EV), can result after smallpox vaccination. Persons at risk for EV include those with underlying dermatologic conditions, such as atopic dermatitis. We investigated a case of vaccinia infection, possibly acquired during sexual contact with a recently vaccinated military service member, in a female Maryland ...
Swanson W F - - 2013
Laparoscopic oviductal AI (LO-AI) with low numbers of freshly collected or frozen-thawed spermatozoa has resulted in high pregnancy success (50-70%) in domestic cats. However, proper timing of AI depends on identifying anestrual, non-luteal queens before exogenous gonadotropin injection, confounding AI scheduling and limiting applicability with felids housed at distant institutions. ...
Peugnet P - - 2013
In equids, placentation is diffuse and the nutrient supply to the fetus is determined by uterine size, which is correlated with maternal size. The size of the mare affects fetal development as shown by embryo transfer (ET) between Ponies and Thoroughbreds. In turn, insulin sensitivity in the newborn foal and ...
Scully Robert R - - 2013
Abstract The pulmonary toxicity of airborne lunar dust was assessed in rats exposed by nose-only inhalation to 0, 2.1, 6.8, 20.8 and 60.6 mg/m3 of respirable size lunar dust. Rats were exposed for 6 h/d, 5 d/week, for 4 weeks (120 h). Biomarkers of toxicity were assessed in bronchial alveolar lavage fluid (BALF) collected ...
Petkov S - - 2013
Small molecule inhibitors acting on the MEK and Wnt signalling pathways (PD0325901 and CHIR99021, respectively) have been used successfully for the maintenance of murine and rat pluripotent stem cells in the in vitro culture. The effects of these compounds in other species have not been conclusively determined, and some reports ...
Kaneko T - - 2013
The rat has been used as an important animal for understanding human diseases. Genetically engineered rat strains are used as a human disease model in various research fields. Genetically engineered rat strains are now being routinely produced, not only as transgenic animals but also using gene knockout techniques. Recently, zinc ...
Real Eusebio E University of Cantabria, Dep. TEISA, Photonics Engineering Group, Avda. Los Castros S/N, 39005 Santander, - - 2013
Optical coherence tomography images of human thoracic aorta from aneurysms reveal elastin disorders and smooth muscle cell alterations when visualizing the media layer of the aortic wall. These disorders can be employed as indicators for wall degradation and, therefore, become a hallmark for diagnosis of risk of aneurysm under intraoperative ...
Tee M Encarlita - - 2013
Discussions about futile treatment options for patients undergoing hematopoietic cell transplantation (HCT) can be difficult for healthcare providers. These discussions often are not initiated before transplantation, but only after a patient's healthcare status deteriorates. Nurses are in a key position to provide support and advocate for patients and their families ...
Cleary J - - 2013
With nearly 1.1 billion inhabitants living in more than 50 countries, Africa is the world's poorest and most socioeconomically underdeveloped continent. Despite some advances for individual states, many African countries have very low opioid consumption and, overall, the continent has the lowest consumption per capita of any in the world. ...
Filippi Massimo - - 2013
Studies with functional MRI (fMRI) of the motor, visual and cognitive networks have consistently demonstrated functional cortical changes in the major multiple sclerosis (MS) clinical phenotypes. Compared with healthy subjects, these fMRI modifications are characterized by an altered recruitment of regions normally devoted to the performance of a given task, ...
Fahrenkrug S C - - 2013
Transcription activator-like effector nuclease (TALEN) and zinc finger nuclease (ZFN) DNA editing technology enables site-directed engineering of the genome. To date, all gene-edited large animals have been produced by treatment of somatic cells and cloning to produce gene-edited offspring. Although effective, it does not take advantage of the 'leave-no-trace' aspect ...
Nagele A - - 2013
It has been previously demonstrated (IETS 2011) that Panama is applying the biotechnology of in vitro embryo production (IVP) to their bovine reproduction management systems. The present work demonstrates the ability to apply the IVP technology across 2 distant country borders. Herein, we demonstrate that a country (Dominican Republic; DR) ...
Cervantes M P - - 2013
Technologies are being developed to conserve the genetic diversity of wood bison. Knowledge of the characteristics of in vivo and in vitro maturation of the cumulus-oocyte complex (COC) are needed in wood bison to design efficient in vitro embryo production protocols. The objectives were to (1) determine the optimal interval ...
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