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Results 301 - 350 of 4089
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Rodríguez Cristina - - 2013
Lactobacillus brevis ADH (LBADH) is an alcohol dehydrogenase that is commonly employed to reduce alkyl or aryl ketones usually bearing a methyl, an ethyl or a chloromethyl as a small ketone substituent to the corresponding (R)-alcohols. Herein we have tested a series of 24 acetophenone derivatives differing in their size ...
Erdreich-Epstein Anat - - 2013
We present here the first report of PID1 (Phosphotyrosine Interaction Domain containing 1; NYGGF4) in cancer. PID1 was first identified in 2006 as a gene that modulates insulin signaling and mitochondrial function in adipocytes and muscle cells. Quantitative RT-PCR, microarrays and cell culture RESULTS: Using four independent medulloblastoma datasets, we ...
Hassan Tidi - - 2013
Retention of abnormal alpha-1 antitrypsin activates the unfolded protein response in alpha-1 antitrypsin deficient monocytes. The regulatory role of microRNAs in unfolded protein responses and chronic obstructive pulmonary disease pathogenesis has not been investigated. To investigate microRNA expression and function in MM and ZZ monocytes and identify microRNA(s) regulating the ...
Lagos Doris M - - 2013
A phylogeny of the genus Aphis Linnaeus, 1758 was built primarily from specimens collected in the Midwest of the USA. A data matrix was constructed with 68 species and 41 morphological characters with respective character states of alate and apterous viviparous females. Dendrogram topologies of analyses performed using UPGMA (Unweighted ...
Shoqirat Noordeen - - 2013
The study examined the level of knowledge of health among hospital nurses in Jordan. Four focus group discussions were carried out with hospital nurses. The findings identified three themes: health as the freedom from illness, health as good social and psychological well-being, and health as a good environment to live ...
Meng Z - - 2013
Anti-annexin1 antibodies are associated with the subtypes of cutaneous lupus and are elevated in systemic lupus erythematosus (SLE) patients. In this study, we investigated the correlation of this antibody with the incidence of SLE skin lesions. The presence of anti-annexin1-IgG and-IgM determined by Western blot was no different among healthy ...
Nobili V - - 2013
Hepatocellular carcinoma (HCC) may develop from non-alcoholic fatty liver disease (NAFLD) either in the presence or in the absence of established cirrhosis. Non-cirrhotic patients with NAFLD-related HCC are usually adult, male and obese. However, this association has not been reported yet in younger age groups. Objectives In the present study, ...
Kim Young-Kyun - - 2013
Abstract This study prospectively evaluated the clinical prognoses of short implants (7 mm long) in the mandible. We investigated the clinical prognosis of short implants in 20 patients (46 implants) according to the installation technique (submerged or non-submerged), installation depth (5.5-mm depth, 7-mm depth), and crown/implant ratio. We investigated the ...
Vandepapelière J - - 2013
ObjectiveThe objective of this paper is to evaluate whether the different International Society of Nephrology/Renal Pathology Society (ISN/RPS) classes of proliferative lupus nephritis (LN) have a distinct baseline presentation, short-term response to immunosuppression (IS) and long-term prognosis.MethodsNinety-eight patients with new onset (first renal biopsy) ISN/RPS proliferative LN (Class III: n = 24; ...
Wong Sze Ling - - 2013
Recent literature has suggested an association between autoimmune thyroiditis and papillary thyroid cancer. The aims of this study were to evaluate if positive thyroid antibodies are associated with thyroid carcinoma and to examine the role of thyroid antibodies in the management of thyroid nodules. This is a database study of ...
Biteau Flore - - 2013
Carnivorous plants have always fascinated scientists because these plants are able to attract, capture, and digest animal prey using their remarkable traps that contain digestive secretions. Nepenthes is one of the largest genera of carnivorous plants, with 120 species described thus far. Despite an outstanding diversity of trap designs, many ...
Macgregor Kylie Anne - - 2013
We reported the first small molecule inhibitors of the interaction between the clathrin N-terminal domain (TD) and endocyctic accessory proteins (i.e clathrin inhibition; 1). Initial screening of a ~17,000 small molecule ChemBioNet library identified 1. Screening of an existing in-house propriety library identified four substituted 1,8-napthalimides as ~80-120 μM clathrin ...
Hoe Susan - - 2013
Abstract Biotherapeutic aerosol formulations are an intense area of interest for systemic and local drug delivery. This article provides a short overview of typical factors required specifically for biotherapeutic aerosol formulation design, the processing options open for consideration, and the issue of inhalation device selection. Focusing on spray drying, four ...
Viljoen Jan-Adriaan - - 2013
The broad austral distribution of Schoeneae is almost certainly a product of long-distance dispersal. Owing to the inadequacies of existing phylogenetic data and a lack of rigorous biogeographic analysis, relationships within the tribe remain poorly resolved and its pattern of radiation and dispersal uncertain. We employed an expanded sampling of ...
Jugulam Mithila - - 2013
The phenoxy herbicides (e.g. 2,4-D and MCPA) are used widely in agriculture for the selective control of broadleaf weeds. In Western Australia, the reliance on phenoxy herbicides has resulted in the widespread evolution of phenoxy resistance in wild radish (Raphanus raphanistrum) populations. In this research the inheritance and mechanism of ...
Guillén Susana - - 2013
Studies of domestication of cacti in the Tehuacán Valley have identified morphophysiological divergences between wild and cultivated populations. To determine whether such divergences are associated with differential survivorship in xeric and mesic environments characterizing wild and cultivated habitats, respectively, we hypothesized that seedlings from cultivated populations are less tolerant of ...
Hanaoka Hirofumi - - 2013
Abstract Carcinoembryonic antigen (CEA) is an attractive target molecule of radioimmunotherapy (RIT). To enhance RIT's therapeutic efficacy, the fractionation of radiolabeled antibody doses is an attractive strategy. In this study, a fully human anti-CEA monoclonal antibody (mAb) C2-45 was selected by virtue of its lack of immunogenicity, and the effectiveness ...
Shivanandan Arun - - 2013
Analyzing spatial distributions of objects in images is a fundamental task in many biological studies. The relative arrangement of a set of objects with respect to another set of objects contains information about potential interactions between the two sets of objects. If they do not "feel" each other's presence, their ...
Finocchiaro Gherardo - - 2013
In this article, we describe a double-chambered left ventricle (LV) associated with a functional right ventricular (RV) aneurysm and right atrial (RA) enlargement in an asymptomatic 24-year-old woman with a family history of sudden cardiac death. We will discuss the differential diagnosis, genetic testing and possible prognostic implications.
Voshaar Thomas - - 2013
Abstract Background: Inhaler mishandling is a common issue among patients suffering from asthma and is associated with poor clinical outcomes and greater consumption of health-care resources. Ease of use can improve inhaler technique and, possibly, patients' preference for their inhaler device, which in turn may lead to better adherence to ...
Golub Eyal - - 2013
This study describes the novel hemin/G-quadruplex DNAzyme-catalyzed aerobic oxidation of thiols to disulfides and the respective mechanism. The mechanism of the reaction involves the DNAzyme-catalyzed oxidation of thiols to disulfides and the thiol-mediated autocatalytic generation of H2O2 from oxygen. The coupling of a concomitant H2O2-mediated hemin/G-quadruplex-catalyzed oxidation of Amplex Red ...
Longest P Worth - - 2013
Abstract Purpose: The objective of this study was to determine optimal aerosol delivery conditions for a full-term (3.6 kg) infant receiving invasive mechanical ventilation by evaluating the effects of aerosol particle size, a new wye connector, and timing of aerosol delivery. Methods: In vitro experiments used a vibrating mesh nebulizer and ...
Cameron E Leslie - - 2013
Hyperosmia is suspected in pregnancy; however, no empirical study using validated measures of olfactory function has clearly confirmed the anecdotal reports of this phenomenon. The goal of the current study is to compare the olfactory sensitivity of pregnant women to that of nonpregnant women and men. All participants rated their ...
Monshupanee Tanakarn - - 2013
Glycogen (GL) and lipids (LP) are efficient biofuel substrates whereas polyhydroxybutyrate (PHB) is a potent bio-degradable plastic. This study aimed to increase accumulation of these three compounds in Synechocystis sp. PCC 6803. Under autophototrophic growth, co-accumulation of the three compounds reached maximum level in a mid-stationary phase at 39.2% of ...
Qiu Wanzhi - - 2013
Graphene nanopores (GNPs) hold great promise as building blocks for electronic circuitry and sensors for biological and chemical sensing applications. Methods to design graphene nanopores that achieve desirable conduction performance and sensing characteristics have not been previously described. Here we present a study of the quantum transport properties of GNPs ...
Singh Ajnesh - - 2013
Biginelli-based molecules (1-3) have been synthesized and developed as a new class of fluorescent organic nanoparticle-based chemosensors. Chemosensor 2 has shown excellent selectivity and sensitivity for detection of Hg(2+) in an aqueous medium. It can detect Hg(2+) up to 1 nM, and the resultant 2Hg(2+) complex can detect Cl(-) ions ...
De Cunto Angela - - 2013
Body mass index (BMI) is correlated with body fatness and risk of related diseases in children and adults. Proportionality indexes such as BMI and ponderal index (PI) have been suggested as complementary measures in neonatal growth assessment. Yet, they are still not used in neonates and their correlation with fatness ...
Janssen Sclinda L - - 2013
The purpose of this study was to explore older adults' perceptions of participation in physical activity (PA) as it impacts productive ageing and informs occupational therapy (OT) practice. In this phenomenological study, 15 community-dwelling older adults were recruited using purposive and snowball sampling at community locations. Data collection methods included ...
Wang Yuzhong - - 2013
In contrast to stable phosphorus oxides such as P4O6 and P4O10 that possess iconic adamantane-like cage structures, highly reactive phosphorus oxides such as PO, PO2, and P2Ox (x = 1-5) only have been studied in the gas phase or by matrix isolation techniques. Elusive diphosphorus tetroxide, the long sought phosphorus ...
Böttcher Joachim - - 2013
Background. The aim of this study was to evaluate imaging-based response to standardized neoadjuvant chemotherapy (NACT) regimen by dynamic contrast-enhanced magnetic resonance mammography (DCE-MRM), whereas MR images were analyzed by an automatic computer-assisted diagnosis (CAD) system in comparison to visual evaluation. MRI findings were correlated with histopathologic response to NACT ...
Hamilton Derek A - - 2013
The recent study by Willams and colleagues utilized a novel robotic virtual reality measurement system to measure sensory-motor processing deficits in children with fetal alcohol spectrum disorders (FASDs). This system and the precise quantitation of distinct constituent behavioral processes may hold considerable utility and importance for the study of FASD-related ...
Asami Kazutaka - - 2013
One-electron oxidized salophen-type complexes, [Cu(salophen)](+) (H2salophen = N,N'-bis(3,5-di-tert-butylsalicylidene)-1,2-diaminobenzene), and its methoxy derivatives, [Cu(MeO-salophen)](+) and [Cu(salophen-(MeO)2)](+) (H2MeO-salophen = N,N'-bis(3-tert-butyl-5-methoxysalicylidene)-1,2-diaminobenzene, H2salophen-(MeO)2 = N,N'-bis(3,5-di-tert-butylsalicylidene)-1,2-diamino-4,5-dimethoxybenzene), have been synthesized and structurally characterized, and their reactivities have been investigated. The solid state structures of the one-electron oxidized forms of these complexes suggested that [Cu(salophen)](+) and [Cu(MeO-salophen)](+) ...
Katsura Morihiro - - 2013
A common dilemma in the management of pelvic fractures is recognizing the presence of associated abdominal injury. The purpose of this study was to determine the association between initial therapeutic intervention (laparotomy or transcatheter arterial embolization (TAE)) and mortality. This was a cohort study using the Japan Trauma Data Bank ...
Townsend Jason M - - 2013
High-elevation ecosystems of the northeastern United States are vulnerable to deposition and environmental accumulation of atmospheric pollutants, yet little work has been done to assess mercury (Hg) concentrations in organisms occupying montane ecosystems. The authors present data on Hg concentrations in ground-foraging insectivorous songbirds, a terrestrial salamander, and forest floor ...
Haslam Iain S - - 2013
For over a century, frogs have been studied across various scientific fields, including physiology, embryology, neuroscience, (neuro)endocrinology, ecology, genetics, behavioural science, evolution, drug development, and conservation biology. In some cases, frog skin has proven very successful as a research model, for example aiding in the study of ion transport through ...
Alserr Ayman H K - - 2013
We report a case of postarthroscopic popliteal artery pseudoaneurysm (PSA) with arteriovenous fistula (AVF; PSA-AVF) in a 53-year-old woman who presented with limb edema, pain, and bruit 1 year after arthroscopic meniscectomy. She was treated percutaneously by covered stent deployment. After 6 months of follow-up, the patient was asymptomatic, with ...
Ukai Tomohiko - - 2013
We report the management of infective endocarditis after an extracardiac Fontan operation. Obstruction of the infected conduit and the associated pulmonary arterial embolism led to failure of the Fontan circulation. This was managed by completely removing both the infected conduit and emboli and replacing the conduit.
Tang Wenxin - - 2013
In this study, we examined whether common variants in the G protein-coupled receptor kinase 6 gene (GRK6) confers susceptibility to schizophrenia in Chinese. We genotyped two common variants in 697 schizophrenia patients and 563 healthy control subjects. No significant difference in either allele or genotype comparisons between the case and ...
Chen Sujuan - - 2013
This study explores the neuroprotective effects and mechanisms of N-acetyl-L-cysteine (NAC) in mice exposed to cadmium (Cd). NAC (150 mg/kg) was intraperitoneally administered to mice exposed to Cd (10-50 mg/L) in drinking water for 6 weeks. The changes of cell damage and death, reactive oxygen species (ROS), antioxidant enzymes, as ...
Poger David - - 2013
Sterols are the hallmarks of eukaryotic membranes where they are often found in specialized functional microdomains of the plasma membrane called lipid rafts. Despite some notable exceptions, prokaryotes lack sterols. However, growing evidence has suggested the existence of raft-like domains in the plasma membrane of bacteria. A structurally related family ...
Barnard Amanda S - - 2013
The discovery of the multipolar surface electrostatic potential on faceted diamond nanoparticles explained numerous observations over the past decades, but also raised questions as to how it could be reconciled with seemingly contradictory observations of micron sized diamond and bulk diamond surfaces. It was also unclear how surface electrostatic potential ...
Bonanomi Sara - - 2013
Collections of historical tissue samples from fish (e.g. scales and otoliths) stored in museums and fisheries institutions are precious sources of DNA for conducting retrospective genetic analysis. However, in some cases only external tags used for documentation of spatial dynamics of fish populations have been preserved. Here we test the ...
Cuzick Jack - - 2013
Background:Cervical screening consumes substantial resources, but little is known about utilization in the United States or compliance with guideline recommendations. Methods:To describe population screening coverage, utilization and outcomes and examine time trends from 2008 to 2011, cervical cytology reports from women residing in New Mexico (981,063 tests from 511,381 women) ...
Charitaki Evangelia - - 2013
Hemodialfiltration (HDF) has been reported to reduce the frequency of intradialytic hypotension compared with hemodialysis (HD). We wished to determine whether HDF resulted in improvement of arterial stiffness compared with HD. We reviewed peripheral blood pressure and pulse wave velocity measurements in a cross-sectional analysis of stable HDF and HD ...
Park Keun Young - - 2013
The purpose of this study was to compare clinical outcomes and treatment-related complications between coiling and clipping for ruptured distal anterior cerebral artery (DACA) aneurysms. Eighty-four consecutive patients (M:F = 36:48; mean 53.8 years) with ruptured DACA aneurysms were treated by either clipping (n = 46, 54.8%) or coiling (n ...
Martín López Juliana Ester - - 2013
The available evidence was reviewed comparing the effectiveness of CT colonography with colonoscopy for CRC screening. An electronic search was conducted using the databases Pubmed, EMBASE, Cochrane library and Centre for Reviews and Dissemination, from inception to July 2009. Studies were included if investigations used CT colonography for CRC screening ...
Markowski Alycia - - 2013
Abstract Background: Cupping, a classic Chinese medicine treatment, is a technique that applies suction cups over soft tissue. Cupping is gaining popularity in physical medicine because of the simplicity in application, minimal adverse effects, and reduction in pain and muscle tenderness. These factors also make it a cost-effective intervention. For ...
Enloe Kimberley A - - 2013
This study evaluated the effects of noncontingent social interaction (SI) on immediate and subsequent engagement in vocal and motor stereotypy in three children with autism. During SI, a therapist delivered continuous interaction in the form of reading aloud from a Kindle™ e-reader. Results showed that when compared with a no-interaction ...
Turner Brianna J - - 2013
We developed a measure of reasons to refrain from nonsuicidal self-injury (NSSI), the Reasons to Stop Self-Injury Questionnaire (RSSIQ), and examined how such reasons are associated with vulnerability versus resiliency for NSSI. Following qualitative item generation, we explored the factor structure, reliability, and convergent validity of the RSSIQ in 218 ...
Hagen Ralf Matthias - - 2013
We evaluated the potential of Cryptosporidium spp. for intentional transmission as a terrorist tactic in asymmetric conflicts in terms of the recognised optimum conditions for biological warfare. Published and widely accepted criteria regarding the optimum conditions for the success of biological warfare based on experience from passive biological warfare research ...
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