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Skinner Anita - - 2013
Atrial fibrillation (AF) is a supraventricular arrhythmia. AF is common, occurs mostly in older people, and is often associated with cardiovascular conditions.
Hadi Kevin - - 2013
Following infection with HIV-1 there is a remarkable variation in virus replication and disease progression. Both host and viral factors have been implicated in the observed differences in disease status. Here we focus on understanding the contribution of HIV-1 viral protein R (Vpr) by evaluating the disease associated Vpr polymorphism ...
Kelly N R - - 2013
Context. U.S. poison centers decrease medical visits by providing telephone advice for home management of potential poisonings, but are underutilized by low-income African-American and Latino parents, and those with limited English proficiency, due to lack of knowledge and misconceptions about poison centers. Objectives. To assess the effectiveness of a poison ...
Pugh Thomas - - 2013
The three-coordinate iron(ii) NHC complexes [(IPr)Fe(N'')2] () and [(I(t)Bu)Fe(N'')2] () (N'' = N(SiMe3)2) react with PhSeH or LiSePh to give the iron(ii) selenolates [(IPr)Fe(N'')(SePh)] () and [I(t)Bu(H)][(aI(t)Bu)Fe(SePh)3], [I(t)Bu(H)][], with complex containing an abnormal NHC ligand.
Hiura Mikio - - 2013
Cerebral blood flow (CBF) during dynamic exercise has never been examined quantitatively using positron emission tomography (PET). This study investigated changes in CBF that occur over the course of a moderate, steady-state cycling exercise. Global and regional CBF (gCBF and rCBF, respectively) were measured using oxygen-15-labeled water (H2(15)O) and PET ...
Zuo Guanghong - - 2013
Ten well-annotated genomes of "Sulfolobus islandicus" strains from different geographic locations have been released at the NCBI database. Whole genome based composition vector trees indicate that these strains show the same branching patterns as originally reported by multi-locus sequence analysis. To determine whether the ten strains meet the criteria for ...
- - 2013
According to the National Institute for Health and Care Excellence (NICE), the UK has the highest rate of child obesity in western Europe. In England alone, around three in ten children aged two to 15 are now classified as either overweight or obese, and hospital admission rates for obesity-related health ...
- - 2013
While most nurses would agree that warm, empathetic human interactions should form the core of their professional practice, defining this largely intangible phenomenon remains challenging.
Thomas Jenny - - 2013
Neonatal anesthesia is fraught with potential risk for the patient and stress for the anesthesiologist. Where possible, recognition of these risks, avoidance of, and being able to manage them appropriately, must impact positively on perioperative outcomes in this vulnerable group of patients. Good communication with the parents, as well as ...
Keogh Kat - - 2013
Nursing numbers could be boosted by a proposed national recruitment campaign, which may include asking former nurses to return to the profession.
Wright Stephen - - 2013
The nursing profession has never been more under the microscope. Inspections by the Care Quality Commission and foundation trust regulator Monitor are on the increase, not to mention the local checks, mystery shoppers and talk of CCTV cameras in care homes.
Percival Jennifer - - 2013
Further to the recent media coverage on the call for smoking be banned from NHS hospital grounds, as a smoking cessation course trainer I would like to point out that smokers are addicted to nicotine.
- - 2013
Members of safe staffing pressure group 4:1 protested last week against the government's decision not to introduce minimum staffing levels.
Keogh Kat - - 2013
Police have launched a criminal investigation into claims that cancer waiting lists were altered at Colchester Hospital University NHS Foundation Trust.
Burleigh Mark - - 2013
Michael Owen believes there is a role for Christian hospital chaplains (Letters October 30), but says they 'should be funded and supported by their local churches or parishioners. They are then accountable to God and their church, not to a formal employer such as the NHS'.
Yanai Anat - - 2013
Transplantation of photoreceptor precursor cells (PPCs) differentiated from human embryonic stem cells (hESCs) is a promising approach to treat common blinding diseases such as age-related macular degeneration and retinitis pigmentosa. However, existing PPC generation methods are inefficient. To enhance differentiation protocols for rapid and high-yield production of PPCs, we focused ...
Degrolard-Courcet Emilie - - 2013
Fanconi anaemia (FA) is characterized by progressive bone marrow failure, congenital anomalies, and predisposition to malignancy. In a minority of cases, FA results from biallelic FANCD1/BRCA2 mutations that are associated with early-onset leukaemia and solid tumours. Here, we describe the clinical and molecular features of a remarkable family presenting with ...
Li Libo - - 2013
Previous work describes a computational solvation model called Semi-Explicit Assembly (SEA). The SEA water model computes the free energies of solvation of nonpolar and polar solutes in water with good efficiency and accuracy. But SEA gives systematic errors in the solvation free energies of ions and charged solutes. Here we ...
Zhang H - - 2013
Lung cancer remains a major cause of cancer-related lethality because of high incidence and recurrence in spite of significant advances in staging and therapy. In present study, we identified a subpopulation of cells isolated from the A549 cell line with marker CD133. In vivo results showed that A549 CD133+ cells displayed high ...
Gobrogge Kyle L - - 2013
Prairie voles (Microtus ochrogaster) are a rodent species that display socially monogamous pair-bonds, a behavior illustrated by several types of social interactions such as mating-induced partner preference, selective aggression toward conspecific strangers, and bi-parental care. Therefore, this species has provided an excellent opportunity for the study of pair-bonding and its ...
- - 2013
Analysis of UK media reporting of the 2009/10 A/H1N1 influenza pandemic has found that public health academics with links to pharmaceutical companies were more likely than other academics to assess the risk to the public as higher than official predictions.
Siegrist M - - 2013
Objective:Childhood obesity is associated with an impaired retinal microcirculation. The aim of the study was to investigate the association between specific obesity-related biomarkers, physical fitness and retinal vessel diameters in school children.Design and Subjects:We studied 381 children aged 10 to 11 years (body mass index: 19.3±3.7 kg/m(2)) in a school-based setting.Measurements:Anthropometric ...
Petersen Bent Ole - - 2013
Complex mixtures of carbohydrates pose distinct challenges in routine and high-throughput analysis, so that only a few carbohydrate components are routinely resolved and identified in biofluids, extracts, foods and other complex mixtures. Here, we conduct precise measurements of (1)H and (13)C anomeric chemical shifts to construct a reference library of ...
O'Brien Frances - - 2013
The physiology of the neonate is ideally suited to the transition to extrauterine life followed by a period of rapid growth and development. Intravenous fluids and electrolytes should be prescribed with care in the neonate. Sodium and water requirements in the first few days of life are low and should ...
Famakin Bolanle M - - 2013
To better understand the role of downstream Toll-like receptor (TLR) signaling during acute cerebral ischemia, we performed cDNA microarrays, on brain RNA, and cytokine arrays, on serum, from wild type (WT), MyD88-/- and TRIF-mutant mice, at baseline and following permanent middle cerebral artery occlusion (pMCAO). The acute stress response pathway ...
Burrows Sharon - - 2013
The increasing emphasis on providing care and treatment in primary and community settings means that nursing students will spend more time there than they have in the past.
Kim J Y - - 2013
Background/Objectives:We studied the relationship between socioeconomic status (SES), represented by household income, and the prevalence of anemia and iron deficiency anemia (IDA) among adolescent girls in Korea.Subjects/Methods:The samples were based on the data from a four-year (2008-2011) collection for the Korea National Health and Nutrition Examination Survey (1312 girls, age ...
Chen F-P - - 2013
Abstract Objective: To explore the effect and pathway of phytoestrogens on the growth of breast cancer cell line MCF-7. Methods: MCF-7 cells (human estrogen -receptor-positive and progesterone-receptor-positive breast cancer cells) were cultured in serum-free medium for 24 h and then treated with genistein, resveratrol, and quercetin (10(-10) to 10(-4) M). After ...
Rutter Ailsa - - 2013
'Fresh' was the UK's first dedicated regional programme to tackle smoking-related illness and death. Established in the north east of England in 2005, the region has since seen adult smoking rates fall at twice the national average.
Wang Quanjun - - 2013
Highly enantioselective hydrogenation of a variety of 2-substituted-2-alkenols has been achieved using a ChenPhos-Rh complex as catalyst, giving ≥99% ee for most substrates. Optically active antifungal agent amorolfine was first synthesised using hydrogenation as the key step.
Luo Guan-Zheng - - 2013
Integrative Short Reads NAvigator (ISRNA) is an online toolkit for analyzing high-throughput small RNA sequencing data. Besides the high-speed genome mapping function, ISRNA provides statistics for genomic location, length distribution and nucleotide composition bias analysis of sequence reads. Number of reads mapped to known microRNAs and other classes of short ...
- - 2013
Directors of nursing are concerned that they may struggle to meet proposed revalidation requirements drawn up by the Nursing and Midwifery Council if they are appraised by their trust chief executive.
Griffiths Matt - - 2013
I am moving from a hospital-based role to primary care where my patients will have a much broader range of conditions. What prescribing advice can you give me?
Price Bob - - 2013
There is widespread recognition that many newly qualified nurses find it difficult to make the transition from completing their university course to taking up their first registered nurse post. Preceptorship programmes during the first year of registered nurse practice have been recommended by the Department of Health. Preceptors have an ...
Pimenta N M - - 2013
Background/Objectives:Heart rate recovery (HRR), a cardiac autonomic control marker, was shown to be related to body composition (BC), yet this was not tested in non-alcoholic fatty liver disease (NAFLD) patients. The aim of this study was to determine if, and to what extent, markers of BC and body fat (BF) ...
Zhu Xiaobo - - 2013
Micelles derived from poly(ε-caprolactone) (PCL) poly(ethylene glycol)(PEG) diblock copolymers (HO-PCLn-b-PEG32-RX, R = -O(CH2)3S(CH2)2-; X = -CO2(-), -SO3(-), -NH3(+)) show corona charge selective degradation catalyzed by P. cepacia lipase isoforms.
Venkataramanan Keerthi P - - 2013
Small non-coding RNAs (sRNA) are emerging as major components of the cell's regulatory network, several possessing their own regulons. A few sRNAs have been reported as being involved in general or toxic-metabolite stress, mostly in Gram- prokaryotes, but hardly any in Gram+ prokaryotes. Significantly, the role of sRNAs in the ...
- - 2013
Labour MSP Jayne Baxter tabled a motion last week in support of RCN Scotland's Health Visitors for Scotland campaign during a parliamentary debate on the Children and Young People Bill. The campaign calls for the bill to specify that the named person caring for under fives is always a health ...
Yang Z - - 2013
The WW domain-containing oxidoreductase (WWOX) gene is a candidate tumor suppressor gene. However, its exact mechanism is unclear. This study aimed to investigate the role of the WWOX gene in the development of nasopharyngeal carcinoma (NPC). Tissues were collected from 65 NPC patients. Reverse transcriptase-polymerase chain reaction (RT-PCR) analysis and immunohistochemistry ...
Bouts Mark J R J - - 2013
Vascular occlusion sites largely determine the pattern of cerebral tissue damage and likelihood of subsequent reperfusion after acute ischemic stroke. We aimed to elucidate relationships between flow obstruction in segments of the internal carotid artery (ICA) and middle cerebral artery (MCA), and (1) profiles of acute ischemic lesions and (2) ...
Guevara James P JP PolicyLab: Center to Bridge Research, Practice, & Policy, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania2Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia3Leonard Davis Institute of Health Economics, University of Pennsylvania, - - 2013
Diversity initiatives have increased at US medical schools to address underrepresentation of minority faculty. To assess associations between minority faculty development programs at US medical schools and underrepresented minority faculty representation, recruitment, and promotion. Secondary analysis of the Association of American Medical Colleges Faculty Roster, a database of US medical ...
Soto Marcelo A - - 2013
Sinc-shaped Nyquist pulses possess a rectangular spectrum, enabling data to be encoded in a minimum spectral bandwidth and satisfying by essence the Nyquist criterion of zero inter-symbol interference (ISI). This property makes them very attractive for communication systems since data transmission rates can be maximized while the bandwidth usage is ...
Dean Erin - - 2013
The concept of formal supervision to help nurses cope with the emotional toll of their jobs has been supported by the government in the wake of the public inquiry into failings at Mid Staffordshire NHS Foundation Trust.
Safavieh Mohammadali - - 2013
Effective pathogen detection is necessary for treatment of infectious diseases. Point of care (POC) devices have tremendously improved the global human heath. However, design criteria for sample processing POC devices for pathogen detection in limited infrastructure are challenging and can make a significant contribution to global health by providing rapid ...
Mone F - - 2013
Abstract Objective To determine if high umbilical artery Doppler (UAD) pulsatility index (PI) is associated with cardio-vascular (CV) risk-factors in children at age 12 years. Methods We studied 195 children at age 12 years who had had in-utero UAD studies performed at 28 weeks gestation. The children were grouped according ...
- - 2013
A procedure to treat open abdominal wounds has been approved as safe by the National Institute for Health and Care Excellence.
Kim Ernest S - - 2013
Reciprocating microfluidic drug delivery, as compared to steady or pulsed infusion, has unique features which may be advantageous in many therapeutic applications. We have previously described a device, designed for wearable use in small animal models, that periodically infuses and then withdraws a sub-microliter volume of drug solution to and ...
Li B - - 2013
Breakdown of the epithelial barrier because of toxins or other insults leads to severe colitis. Interleukin-10 (IL-10) is a critical regulator of this, yet its cellular targets and mechanisms of action are not resolved. We address this here. Mice with a macrophage-selective deletion of IL-10Rα (IL-10Rα(Mdel)) developed markedly enhanced dextran ...
Delgado-Esteban Maria - - 2013
The morphology of the adult brain is the result of a delicate balance between neural progenitor proliferation and the initiation of neurogenesis in the embryonic period. Here we assessed whether the anaphase-promoting complex/cyclosome (APC/C) cofactor, Cdh1-which regulates mitosis exit and G1-phase length in dividing cells-regulates neurogenesis in vivo. We use ...
Burle Borís - - 2013
In conflict tasks, the irrelevant stimulus attribute needs to be suppressed for the correct response to be produced. In the Simon task, earlier researchers have proposed that this suppression is the reason that, after an initial increase, the interference effect decreases for longer RTs, as reflected by late, negative-going delta ...
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