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Rutter Ailsa - - 2013
'Fresh' was the UK's first dedicated regional programme to tackle smoking-related illness and death. Established in the north east of England in 2005, the region has since seen adult smoking rates fall at twice the national average.
Delancey Marian - - 2013
The government's response to the Francis report (Editorial, News and Analysis November 27) sounds promising, but does this mean that yet more administration staff will need to be employed to ascertain and publish the figures and data on staffing levels?
Turner Steve - - 2013
Peter Cheese (Letters September 18) says zero-hours contracts can work for employers and employees. As chief executive of the Chartered Institute of Personnel and Development, he claims that zero-hours contracts have been 'unfairly demonised'.
Benjamin Caroline - - 2013
This is the seventh article in a series examining how nurses can develop confidence and competence in genetics and genomics health care. This article focuses on identifying the nurse's awareness of genetic and genomic issues and the effect this has on his or her practice. It considers the importance of ...
Mooney Tracy - - 2013
Bell's palsy (idiopathic facial paralysis) is the most common cause of acute unilateral facial nerve paralysis. Although it is usually a self-limiting condition, it can be distressing for the patient. Many people who experience one-sided facial paralysis fear that it is a symptom of stroke. However, there are subtle differences ...
Price Bob - - 2013
There is widespread recognition that many newly qualified nurses find it difficult to make the transition from completing their university course to taking up their first registered nurse post. Preceptorship programmes during the first year of registered nurse practice have been recommended by the Department of Health. Preceptors have an ...
Skinner Anita - - 2013
Atrial fibrillation (AF) is a supraventricular arrhythmia. AF is common, occurs mostly in older people, and is often associated with cardiovascular conditions.
Allen Daniel - - 2013
'Try to do at least four times more preparation than you think is enough,' says career strategist John Lees, author of How to Get a Job You'll Love.
Dean Erin - - 2013
The concept of formal supervision to help nurses cope with the emotional toll of their jobs has been supported by the government in the wake of the public inquiry into failings at Mid Staffordshire NHS Foundation Trust.
Burrows Sharon - - 2013
The increasing emphasis on providing care and treatment in primary and community settings means that nursing students will spend more time there than they have in the past.
Delgado-Esteban Maria - - 2013
The morphology of the adult brain is the result of a delicate balance between neural progenitor proliferation and the initiation of neurogenesis in the embryonic period. Here we assessed whether the anaphase-promoting complex/cyclosome (APC/C) cofactor, Cdh1-which regulates mitosis exit and G1-phase length in dividing cells-regulates neurogenesis in vivo. We use ...
Leijtens Tomas - - 2013
The power conversion efficiency of hybrid solid-state solar cells has more than doubled from 7 to 15% over the past year. This is largely as a result of the incorporation of organometallic trihalide perovskite absorbers into these devices. But, as promising as this development is, long-term operational stability is just ...
Hara Toru - - 2013
Ultrabrilliant, femtosecond X-ray pulses from X-ray free-electron lasers (XFELs) have promoted the investigation of exotic interactions between intense X-rays and matters, and the observation of minute targets with high spatio-temporal resolution. Although a single X-ray beam has been utilized for these experiments, the use of multiple beams with flexible and ...
Gillen Sally - - 2013
England's most senior nurse has urged all hospitals to publish a range of information each month that will 'shine a light' on the care they provide.
Percival Jennifer - - 2013
Further to the recent media coverage on the call for smoking be banned from NHS hospital grounds, as a smoking cessation course trainer I would like to point out that smokers are addicted to nicotine.
Burleigh Mark - - 2013
Michael Owen believes there is a role for Christian hospital chaplains (Letters October 30), but says they 'should be funded and supported by their local churches or parishioners. They are then accountable to God and their church, not to a formal employer such as the NHS'.
Sarcher Christian - - 2013
Gold(i) complexes ligated by phosphines with N-heterocycles in the periphery were prepared. First the synthesis of the ligands N-(diphenylphosphino)-4-(pyridin-2-yl)pyrimidin-2-amine (Hpypya) and N-(diphenylphosphino)-4-phenylpyrimidin-2-amine (Hphpya) are reported. These two compounds together with the related but earlier published ligands 3-(2-(diphenylphosphino)phenyl)-1H-pyrazole (Hph3py) and 5-(4-(diphenylphosphino)phenyl)-1H-pyrazole (Hph5py) were reacted with [(tht)AuCl] and [Au(tht)2]ClO4 to give the ...
Wang Lei - - 2013
Somatic mutations in the epidermal growth factor receptor (EGFR) gene were associated with sensitivity to small molecule tyrosine kinase inhibitors for patients with lung adenocarcinomas. In this research, EGFR mutation status was analyzed by DNA sequencing in 153 lung adenocarcinoma tissues. Of these, 75 samples carried EGFR mutations, including 29 ...
Chambers Stuart M - - 2013
The neural crest (NC) is a transient population of multipotent cells giving rise to the peripheral nervous system, skin pigmentation, heart, and facial mesenchyme. The broad cell fate potential of NC makes it an attractive cell fate to derive from human pluripotent stem cells (hPSCs) for exploring embryonic development, modeling ...
Martins Ana M - - 2013
Biomimetic calcium phosphate coating (CaP) methodology mimics the natural biomineralization process of bone, which involves two phases: nucleation and growth. In this chapter we present a successful method to coating biodegradable natural-origin materials with biomimetic CaP layer as a strategy to incorporate enzymes with the main aim of controlling and ...
Li Nan - - 2013
Adaptive radiation therapy (ART) can reduce normal tissue toxicity and/or improve tumor control through treatment adaptations based on the current patient anatomy. Developing an efficient and effective re-planning algorithm is an important step toward the clinical realization of ART. For the re-planning process, manual trial-and-error approach to fine-tune planning parameters ...
Voruganti V Saroja - - 2013
Increased serum uric acid (SUA) or hyperuricemia, a risk factor for gout, renal and cardiovascular diseases, is caused by either increased production or decreased excretion of uric acid or a mix of both. The solute carrier protein 2 family, member 9 (SLC2A9) gene encodes a transporter that mediates urate flux ...
Döcker Dennis - - 2013
SATB2 is an evolutionarily highly conserved chromatin remodeling gene located on chromosome 2q33.1. Vertebrate animal models have shown that Satb2 has a crucial role in craniofacial patterning and osteoblast differentiation, as well as in determining the fates of neuronal projections in the developing neocortex. In humans, chromosomal translocations and deletions ...
Safavieh Mohammadali - - 2013
Effective pathogen detection is necessary for treatment of infectious diseases. Point of care (POC) devices have tremendously improved the global human heath. However, design criteria for sample processing POC devices for pathogen detection in limited infrastructure are challenging and can make a significant contribution to global health by providing rapid ...
Van Zundert T - - 2013
Background: Extraglottic airway devices (EADs) are frequently used airway devices, yet often they seal poorly, resulting in a functionally unacceptable leak. Optimal size selection of the EAD is therefore critical to the safe and effective use of an EAD. This review is designed to delineate the sizing recommendations of EADs ...
Bouhemad B - - 2013
Background: Lung ultrasound can be used at bedside to assess initial lung morphology in hypoxemic patients. We hypothesized that blood flow in consolidated lung and therefore effects of inhaled nitric oxide (iNO) and intravenous almitrine could be directly assessed using Doppler transesophageal echocardiography (TEE). Methods. We conducted a prospective study ...
Kalimeris K - - 2013
Background: Sevoflurane exerts effects on pulmonary cells that could protect against lung injury. We evaluated the potential of pretreatment with sevoflurane to attenuate lipopolysaccharide (LPS)-induced lung injury. Methods: LPS was administered intratracheally in Wistar rats to induce lung injury. Sevoflurane was administered for 30 min at 0.25, 0.5 or 1.0 ...
Kim Ernest S - - 2013
Reciprocating microfluidic drug delivery, as compared to steady or pulsed infusion, has unique features which may be advantageous in many therapeutic applications. We have previously described a device, designed for wearable use in small animal models, that periodically infuses and then withdraws a sub-microliter volume of drug solution to and ...
Kim J Y - - 2013
Background/Objectives:We studied the relationship between socioeconomic status (SES), represented by household income, and the prevalence of anemia and iron deficiency anemia (IDA) among adolescent girls in Korea.Subjects/Methods:The samples were based on the data from a four-year (2008-2011) collection for the Korea National Health and Nutrition Examination Survey (1312 girls, age ...
Nehring I - - 2013
Background/objective:Anorexia nervosa (AN) is a severe eating disorder with a high mortality rate. Treatment regimes show regional and global variation and are sometimes supported by enteral feeding (EF) via nasogastric tube, although risks and benefits are still unclear. We aimed to find out whether EF improves growth and AN recovery ...
Pimenta N M - - 2013
Background/Objectives:Heart rate recovery (HRR), a cardiac autonomic control marker, was shown to be related to body composition (BC), yet this was not tested in non-alcoholic fatty liver disease (NAFLD) patients. The aim of this study was to determine if, and to what extent, markers of BC and body fat (BF) ...
Gemming L - - 2013
Background/Objectives:The most recent New Zealand Adult Nutrition Survey 2008/09 (ANS 08/9) revealed a decrease in reported energy intakes (EIs) compared with the previous 1997 National Nutrition Survey (NNS97). Conversely, measured body weights increased over the same period. We conducted an analysis on the ANS 08/9 data sets to evaluate reported ...
O'Brien Frances - - 2013
The physiology of the neonate is ideally suited to the transition to extrauterine life followed by a period of rapid growth and development. Intravenous fluids and electrolytes should be prescribed with care in the neonate. Sodium and water requirements in the first few days of life are low and should ...
Kim Donghyuk - - 2013
Mesoporous silica nanoparticles are promising drug delivery agents; however, their interaction with various in vivo biological components is still under investigation. In this work, the impact of sub-50 nm diameter mesoporous silica nanoparticles on platelet function is investigated using a microfluidic platform to model blood vessel characteristics. Platelet adhesion and ...
Thomas Jenny - - 2013
Neonatal anesthesia is fraught with potential risk for the patient and stress for the anesthesiologist. Where possible, recognition of these risks, avoidance of, and being able to manage them appropriately, must impact positively on perioperative outcomes in this vulnerable group of patients. Good communication with the parents, as well as ...
Sloan Paul - - 2013
Chronic pain is frequently treated with our most potent analgesics, the opioids. While immediate-release opioids given every 3 - 4 h provide adequate analgesia for most patients with cancer pain and some patients with chronic nonmalignant pain, extended-release (ER) opioid formulations have been developed in the hope that patients with ...
Gabbay-Benziv Rinat - - 2013
Abstract Objective: To determine the association between decision to delivery interval and short term perinatal outcome in cases of suspected placental abruption delivered by cesarean section (CS). Study Design: A retrospective cohort study of all cases of placental abruption delivered by CS (2010-2012) in a single university affiliated tertiary center. ...
Arcau Julià - - 2013
The synthesis and characterization of three propynyloxycoumarins are reported in this work together with the formation of three different series of gold(i) organometallic complexes. Neutral complexes are constituted by water soluble phosphines (PTA and DAPTA) which confer water solubility to them. The X-ray crystal structure of 7-(prop-2-in-1-yloxy)-1-benzopyran-2-one and its corresponding ...
Shufaro Yoel - - 2013
Abstract The maternal age at the first and repeated deliveries constantly rises in developed countries due to current social trends that favor values of personal achievements upon procreation. Assisted reproduction technologies (ART) and especially the availability of oocyte donation programs extend the age of fecundity to the fifth and sixth ...
Esser Diederik - - 2013
Flavanol-enriched chocolate consumption increases endothelium-dependent vasodilation. Most research so far has focused on flow-mediated dilation (FMD) only; the effects on other factors relevant to endothelial health, such as inflammation and leukocyte adhesion, have hardly been addressed. We investigated whether consumption of regular dark chocolate also affects other markers of endothelial ...
Li Neng - - 2013
We have investigated the mechanism of densification of a nearly perfect continuous random network (CRN) model of amorphous SiO2 (a-SiO2) glass with 1296 atoms and periodic boundary conditions. The model has no under- or over-coordinated atoms and small bond length and bond angle distributions. This near-perfect model is systematically densified ...
Huang Shouqiang - - 2013
Upconversion photocatalysts have the potential to absorb the near-infrared (NIR) light in solar energy and improve the photocatalytic performance. A hierarchical upconversion photocatalyst of BiVO4 (BVO)/CaF2:Er(3+), Tm(3+), Yb(3+) (CF) combined with the narrow-band semiconductor of BVO and the luminescence agent of CF to enhance upconversion properties was synthesized via the ...
Pedreira Denise A L - - 2013
Abstract Objective: To report our preliminary clinical experience in the antenatal correction of open spina bifida using a fetoscopic approach and a simplified closure technique. Methods: Four fetuses with lumbar-sacral defects were operated in utero from 25 to 27 weeks. Surgeries were performed percutaneously under general anesthesia using three trocars ...
Stovicek Jan - - 2013
Abstract Objective. Neurological complications of inflammatory bowel diseases (IBDs) are not rare but are under-diagnosed; some are probably immune-mediated. Several previous studies have suggested a higher incidence of demyelinating diseases such as multiple sclerosis in IBD patients. In this single-center, prospective, observational study, the authors focus on T2 focal white-matter ...
Wu Lina - - 2013
Advanced methods are urgently needed to determine the identity and viability of trace amount of pathogenic bacteria in a short time. Existing approaches either fall short in the accurate assessment of microbial viability or lack of specificity in bacterial identification. Bacteriophages (or phages for short) are viruses that exclusively infect ...
Singh Jay - - 2013
In this paper, we present results of the studies related to fabrication of a rare earth metal oxide based efficient biosensor using an interface based on hydrothermally prepared nanostructured thulium oxide (n-Tm2O3). A colloidal solution of prepared nanorods has been electrophoretically deposited (EPD) onto an indium-tin-oxide (ITO) glass substrate. The ...
Bodmann Eva-Lisa - - 2013
Some G‑protein‑coupled receptors regulate biological processes via Gα12/13‑ or Gαq/11‑mediated stimulation of Rho guanine nucleotide exchange factors (RhoGEFs). p63RhoGEF is known to be specifically activated by Gαq/11 and mediates a major part of the acute response of vascular smooth muscle cells to Angiotensin II treatment. In order to gain information ...
Kameyama Hiroki - - 2013
Adult male mice were continuously treated with bromodeoxyuridine (BrdU) for 1, 2, or 4 weeks by an osmotic pump. To detect BrdU-label-retaining cells (LRCs), putative progenitor/stem cells, other animals were continuously treated with BrdU for 2 weeks, and were then kept without any treatments for 2, 6, or 18 months. ...
Oben Jolien - - 2013
Abstract Objective - In this study we determine whether maternal cardiovascular profiling can detect first trimester differences between women with uncomplicated pregnancies (UP) and those who will develop gestational hypertensive disorders (GHD) or normotensive fetal growth retardation (FGR). Methods - Cardiac, arterial, and venous function were evaluated in 242 pregnant ...
Imai H - - 2013
The effects of first-line chemotherapy on overall survival (OS) might be confounded by subsequent therapies in patients with non-small cell lung cancer (NSCLC). We examined whether progression-free survival (PFS), post-progression survival (PPS), or tumor response could be valid surrogate endpoints for OS after first-line chemotherapies in advanced NSCLC by using ...
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