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Results 251 - 300 of 3199
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Kute Vivek B - - 2013
Abstract Background: Kidney paired donation (KPD) is a rapidly growing modality for facilitating living donor kidney transplantation (LDKTx) for patients who are incompatible with their healthy, willing and living donor. The impact of donor-recipient age difference on long and short-term graft and patient survivals in LDKTx is still uncertain. Methods: ...
Martins André F - - 2013
In an effort towards the visualization of β-amyloid (Aβ) plaques by T 1-weighted magnetic resonance imaging for detection of Alzheimer's disease, we report the synthesis and characterization of stable, noncharged Gd(3+) complexes of three different 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid monoamide derivatives conjugated to Pittsburgh compound B, a well-established marker of Aβ plaques. The ...
Vllasaliu Driton - - 2013
Introduction: Recent biopharma deals related to nanocarrier drug delivery technologies highlight the emergence of nanomedicine. This is perhaps an expected culmination of many years of research demonstrating the potential of nanomedicine as the next generation of therapeutics with improved performance. PEGylated nanocarriers play a key role within this field. Areas ...
Bartnik Magdalena - - 2013
We used whole-genome exon-targeted oligonucleotide array comparative genomic hybridization (array CGH) in a cohort of 256 patients with developmental delay (DD)/intellectual disability (ID) with or without dysmorphic features, additional neurodevelopmental abnormalities, and/or congenital malformations. In 69 patients, we identified 84 non-polymorphic copy-number variants, among which 41 are known to be ...
Ye Qiang - - 2013
Macrophages and vascular smooth muscle cells (VSMCs) are the major cell types involved in foam cell formation associated with atherosclerosis. The aim of this experiment was to clarify cell-specific regulation of LDL receptor in THP-1 macrophages and human VSMCs under physiological and inflammatory conditions and its potential mechanisms. Inflammatory stress ...
Hassanian-Moghaddam Hossein - - 2013
We aimed to evaluate the efficacy of QT dispersion (QTD) in determining the outcome of the patients poisoned by cardiotoxic medications and toxins. Patients who referred to our emergency department (ED) due to acute toxicity with any cardiotoxic medication or toxin and were admitted to medical toxicology intensive care unit ...
Kumar Vikash - - 2013
A high titre of thermo-alkali-stable xylanase was attained in cane molasses medium. When the culture variables for endoxylanase production were optimized [cane molasses 7 %, soluble alkaline extract of wheat bran (SAE-WB) 37 % and ammonium chloride 0.30 %], a 4.5-fold enhancement in xylanase production (69 U ml(-1)) was achieved as compared to that in ...
Breathnach C S - - 2013
It was in Saint-Julien near Villefranche that Claude Bernard was born on 12 July 1813. About 20 years later he moved to Paris to become a dramatist but was directed into the study of medicine, the service at the Hôtel Dieu of Magendie that led him to the Collège de France. ...
De Prá Samira D T - - 2013
Mutations in the tyrosine aminotransferase gene have been identified to cause tyrosinemia type II which is inherited in an autosomal recessive manner. Studies have demonstrated that an excessive production of ROS can lead to reactions with macromolecules, such as DNA, lipids, and proteins. Considering that the L-tyrosine may promote oxidative ...
Liao Hui-Yi - - 2013
Abstract The aim of this study was to identify the health hazards and possible exposure surveillance markers of workers exposed to nanoparticles during manufacturing and application in comparison to a group of unexposed workers. For this longitudinal study, we recruited 158 nanomaterial-handling workers and 104 non-exposed workers from 14 manufacturing ...
Huang Ruiwang - - 2013
Many previous studies suggested that both short-term and long-term motor training can modulate brain structures. However, little evidence exists for such brain anatomical changes in top-level gymnasts. Using diffusion-weighted and structural magnetic resonance images of the human brain, we applied voxel-based morphometry (VBM) and tract-based spatial statistics (TBSS) as well ...
Quddus Ehtesham B - - 2013
A novel method for synthesis of high quality InN nanowires, at temperatures well above their decomposition temperature, has been demonstrated by utilizing controlled oxygen flow in the growth chamber. Detailed structural and chemical analyses indicate that the nanowires consist of pure InN, with no evidence of In2O3 detected by any ...
Mbah Chukwuemeka C - - 2013
Introduction: The application of vesicular carrier formulations has generated promise of overcoming some problems associated with drug delivery arising from not only the physicochemical properties of the drug but also those of the biological barriers, such as the membrane linings of various body tissues and the skin. This review article ...
Xia Qiuling - - 2013
Respiratory syncytial virus (RSV) causes respiratory tract infection, particularly acute lower respiratory tract infection (ALRTI), in early childhood. The RSV fusion protein (F protein) is an important surface protein, and it is the target of both cytotoxic T lymphocytes (CTL) and neutralizing antibodies; thus, it may be useful as a ...
Böckenholt Ulf - - 2013
Asking sensitive or personal questions in surveys or experimental studies can both lower response rates and increase item non-response and misreports. Although non-response is easily diagnosed, misreports are not. However, misreports cannot be ignored because they give rise to systematic bias. The purpose of this paper is to present a ...
Mishra Gita D - - 2013
Physical and mental component summary scores (PCS and MCS, respectively) are often used to summarise SF-36 quality of life subscales. This paper investigates PCS and MCS across the life course and compares the trajectories obtained from two different methods of calculation. The Australian Longitudinal Study on Women's Health is a ...
Sharma S K - - 2013
Carbon based nanofillers have shown phenomenal improvements in thermo-mechanical properties of poly vinyl alcohol (PVA) based nanocomposites depending on their interaction with PVA molecules and dispersion in the polymer matrix. In the present study, PVA based nanocomposites with amino-functionalized multi-wall carbon nanotubes (fMWCNTs, 0.2, 0.4, 0.8 and 1.0 wt%) were ...
Sullan Ruby May A - - 2013
Although bacterial pili are known to mediate cell adhesion to a variety of substrates, the molecular interactions behind this process are poorly understood. We report the direct measurement of the forces guiding pili-mediated adhesion, focusing on the medically important probiotic bacterium Lactobacillus rhamnosus GG (LGG). Using non-invasive single-cell force spectroscopy ...
Shin Daniel H - - 2013
Since the advent of intracytoplasmic sperm injection in 1992, sperm retrieval procedures have been routinely employed to treat male infertility owing to azoospermia. With obstructive azoospermia, sperm is potentially harvestable from the vas deferens, epididymis, and testicle using percutaneous and open sperm retrieval procedures that are relatively straightforward and reliable. ...
Kinney Melissa A - - 2013
The physiochemical stem cell microenvironment regulates the delicate balance between self-renewal and differentiation. The three-dimensional assembly of stem cells facilitates cellular interactions that promote morphogenesis, analogous to the multicellular, heterotypic tissue organization that accompanies embryogenesis. Therefore, expansion and differentiation of stem cells as multicellular aggregates provides a controlled platform for ...
Myśków Beata - - 2013
The development of genetic maps is, nowadays, one of the most intensive research activities of plant geneticists. One of the major goals of genome mapping is the localisation of quantitative trait loci (QTLs). This study was aimed at the identification of QTLs controlling morphological traits of rye and comparison of ...
Mehta Shaine - - 2013
To examine the pregnancy outcomes of women >45 years in a multi-ethnic population when compared to controls and to reflect on socio-demographic details of the older mothers. A retrospective cohort control study over an 8-year period in an inner city London hospital with multi-ethnic population. The influence of advanced maternal age ...
Li Chunmei - - 2013
Choerospondias axillaris (Guangzao) is a medicinal plant used in Mongolia, and its fruit is commonly used for the treatment of cardiovascular diseases in clinic. The constituents responsible for this effect are always conceded to be the total flavonoids of C. axillaries (TFC). The present study was to evaluate the preventive ...
Bae Hyokwan - - 2013
Poly(vinyl alcohol) (PVA) has been utilized as a support material for the immobilization of nitrifying bacteria without the comprehensive survey of partial nitritation. In the present study, the activities of nitrifiers and the maximum nitrogen conversion rate of partial nitritation with PVA sponge-cubes were specified according to different conditions. The ...
Pompe Manca Tekavčič - - 2013
The purpose of this study was to investigate chromatic visual evoked potential (cVEP) response characteristics during the first year of life and to collect as large database of healthy baby responses as possible. This study also complements our previous studies on cVEP in schoolchildren and preschool children. Forty-four healthy babies ...
Wojcik Pawel Jerzy - - 2013
An efficient mathematical strategy in the field of solution processed electrochromic (EC) films is outlined as a combination of experiment work, modelling and information extraction from massive computational data via statistical software. This paper describes a case study in which Design of Experiment (DOE) for mixtures was used for statistical ...
Ramasamy Parthiban - - 2013
A novel rear reflector structure that combines NIR light harvesting β-NaGdF4:Yb, Er, Fe upconversion nanoparticles (UCNPs) and light reflecting silver particles has been successfully used to improve the performance of dye-sensitized solar cells (DSSCs). The power conversion efficiency of DSSCs with a rear reflector was 7.04%, which is an increase ...
Zakharova Maria V - - 2013
A series of asymmetrically substituted sulfonium derivatives of nido-carborane [9-R(Me)S-nido-7,8-C2B9H11] (R = Et, Pr, Bu, Bn, CH[double bond, length as m-dash]CH2, CH2CH[double bond, length as m-dash]CH2, CH2C[triple bond, length as m-dash]CH, CH[double bond, length as m-dash]C[double bond, length as m-dash]CH2) were prepared by alkylation of the 9-methylthio-nido-7,8-carborane. The synthesized compounds ...
Xu Yi-Wei - - 2013
OBJECTIVES:Esophageal squamous cell carcinoma (ESCC) is one of the most frequent causes of cancer death worldwide and effective diagnosis is needed. We assessed the diagnostic potential of an autoantibody panel that may benefit early diagnosis.METHODS:We analyzed data for patients with ESCC and normal controls in a test cohort and a ...
Eggers Sander M - - 2013
Despite its popularity, few studies have assessed the temporal stability and cross-lagged effects of the Theory of Planned Behavior factors: Attitude, subjective norms and self-efficacy. For this study, 298 adolescent learners from KwaZulu-Natal, South Africa, filled out a Theory of Planned Behavior questionnaire on teenage pregnancy at baseline and after ...
Tan Kuan-Boone - - 2013
Aim: The aim of this work was to develop a liposomal formulation to facilitate delivery of a synergistic safingol/C2-ceramide combination in the treatment of acute myeloid leukemia (AML). Materials & methods: Liposomes were prepared using the extrusion method and the bioactive lipids were encapsulated passively. Drug concentrations were determined by ...
Shah Lipa - - 2013
Although neuro-active peptides are highly potent as central nervous system (CNS) therapeutics, their systemic delivery across the blood-brain barrier (BBB) is limited due to lack of permeability in the brain and rapid systemic metabolism. In this study, we aimed at enhancing the brain delivery and stability of chemically modified [D-Arg(2), ...
Watanabe Jun - - 2013
Although obesity is considered as a risk factor for postoperative morbidity in abdominal surgery, its effect on the outcomes of laparoscopic-assisted colectomy (LAC) is still unclear. The technical difficulty and risk factor for postoperative complication in LAC are thought to be influenced by visceral obesity. The aim of this prospective ...
He Liyu - - 2013
Abstract Imbalance of Th1/Th2 pro-inflammatory cytokines plays an important role in the development and progression of IgA nephropathy (IgAN). Clinical development and exacerbation of IgAN are frequently preceded by episodes of upper respiratory tract infection, and palatine tonsils represent the predominant immunocompetent tissue of the upper respiratory tract. This study ...
Wang Ling-Jia - - 2013
We are reporting first successful intrahepatic autologous islet transplantation after total pancreatectomy in a patient with chronic pancreatitis and primary sclerosing cholangitis. Total pancreatectomy and subsequent islet autotransplantation were performed in a 16-year-old boy with intractable pain due to chronic pancreatitis in the setting of ulcerative colitis and primary sclerosing ...
Medvecky Lubomir - - 2013
Porous polyhydroxybutyrate (PHB)-chitosan biopolymer scaffolds were prepared by co-precipitation from biopolymer solutions with propylene carbonate and acetic acid as solvents. A change of the fibrous character of chitosan precipitates to globular shaped forms with a polyhydroxybutyrate addition was found in suspensions. Scaffolds differ by porosity and morphology of polymers in ...
Ermler Sibylle - - 2013
Combinations of genotoxic agents have frequently been assessed without clear assumptions regarding their expected (additive) mixture effects, often leading to claims of synergisms that might in fact be compatible with additivity. We have shown earlier that the combined effects of chemicals, which induce micronuclei (MN) in the cytokinesis-block micronucleus assay ...
Van Citters Aricca D - - 2013
Total joint arthroplasty (TJA) is one of the most widely performed elective procedures; however, there are wide variations in cost and quality among facilities where the procedure is performed. The purposes of this study were to (1) develop a generalizable clinical care pathway for primary TJA using inputs from clinical, ...
Singh Ramandeep - - 2013
To evaluate the feasibility and short-term outcome of 23-gauge vitrectomy in children for various vitreoretinal conditions. A retrospective chart review was conducted of consecutive children younger than 14 years who underwent 23-gauge transconjunctival sutureless vitrectomy for various vitreoretinal conditions from January 2008 to December 2011 at a tertiary care center. ...
Panfili Elisabetta - - 2013
The purpose of the study was to compare the artefacts produced by different hip prostheses on magnetic resonance imaging (MRI). An identical MRI protocol was used to perform a quali-quantitative in vitro evaluation of artefacts caused by different hip prosthetic materials at different field strengths: prosthesis number 1, composed of ...
Nikoloulopoulos Aristidis K - - 2013
Factor or conditional independence models based on copulas are proposed for multivariate discrete data such as item responses. The factor copula models have interpretations of latent maxima/minima (in comparison with latent means) and can lead to more probability in the joint upper or lower tail compared with factor models based ...
Li Gang - - 2013
A 62-year-old woman with hypertension, type 2 diabetes mellitus, hyperlipemia and coronary heart disease started taking clopidogrel, with no addition of any other new drugs. However, with the addition of the drug, the patient was diagnosed as having acquired pure red cell aplasia (PRCA), and no any other inducing factors ...
Azadi Ali - - 2013
To evaluate the effect of surgical instruments handling on polypropylene mesh using scanning electron microscopy (SEM). We applied different surgical instruments, including a few robotic ones, to pieces of polypropylene mesh. SEM was used to evaluate the morphological changes with this intervention. Straight hemostat, laparoscopic atraumatic grasper, laparoscopic needle driver, ...
Ruiz-Ibán Miguel Angel - - 2013
Long-bone segmental defects caused by infection, fracture, or tumour are a challenge for orthopaedic surgeons. Structural allografts are sometimes used in their treatment but their poor biological characteristics are a liability. The objective of this study was to determine whether the addition of recombinant vascular endothelial growth factor-A (VEGF) to ...
Verdoia Monica - - 2013
Periprocedural myocardial infarction (PMI) represents a frequent complication in patients undergoing percutaneous coronary revascularization. Despite great attention focused on pharmacological prevention of periprocedural damage, very little is known about using biomarkers to potentially predict the risk of PMI. Larger platelets have been associated with enhanced reactivity, increased cardiovascular risk, and ...
Ferranti E J S - - 2013
Quantifying the sources of fugitive dusts on complex industrial sites is essential for regulation and effective dust management. This study applied two recently-patented Directional Passive Air Samplers (DPAS) to measure the fugitive dust contribution from a Metal Recovery Plant (MRP) located on the periphery of a major steelworks site. The ...
Rahman Shahidur - - 2013
The present manuscript provides a detailed physicochemical and thermodynamic characterization of 9-aminocamptothecin (9AC) which can be used as a tool to develop novel formulation strategies for optimum pharmacological activity. The pK a of 9AC was determined to be 2.43 at 37°C, while the basicity of quinoline nitrogen of 9AC was ...
Govi Silvia - - 2013
ABSTRACT Indolent lymphomas primarily involving the skeleton (iPBL) represent <1% of all primary bone lymphomas. The management and prognosis have not been previously described. Patients with primary and secondary iPBL were selected from an international database of 499 patients with a histopathological diagnosis of non-Hodgkin lymphoma and skeleton involvement, and ...
Houde Vanessa P - - 2013
The LKB1 tumour suppressor protein kinase functions to activate two isoforms of AMP-activated protein kinase (AMPK) and 12 members of the AMPK-related family of protein kinase. The highly conserved C-terminal residues of LKB1 are phosphorylated (Ser431) by PKA and RSK and farnesylated (Cys433) within a CAAX motif. To better define ...
Heck Matthias M - - 2013
The aim of this study was to prospectively compare diffusion-weighted magnetic resonance imaging (DWI) and [(11)C]choline positron emission tomography/computed tomography (PET/CT) with computed tomography (CT) for preoperative lymph node (LN) staging in prostate cancer (PCa) patients. Between June 2010 and May 2012, CT, DWI and [(11)C]choline PET/CT were performed preoperatively ...
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