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Results 201 - 250 of 3199
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Kanarek Gerard - - 2013
In the present study, we investigate the effect extrinsic (habitat and season) and intrinsic (host's age and sex) factors on the richness, diversity, and structure of parasite component communities and aggregation patterns in the helminth fauna of the great cormorant Phalacrocorax carbo from northeastern Poland. The helminth fauna of cormorants ...
Krentz Hartmut B - - 2013
Antiretroviral drug resistance (ARV) limits choices often necessitating the selection of drugs with less desirable pill burdens, toxicity profiles, drug interactions, dosing schedules, and may increase cost. We examine the impact of resistance on the cost of HIV care. All adult HIV-positive individuals newly referred for HIV care from 1/1/2007-1/1/2011 ...
Arazpour M M Orthotics and Prosthetics Department, University of Social Welfare and Rehabilitation Sciences, Tehran, - - 2014
The aim of this study was to evaluate the effect of a powered gait orthosis (PGO) on the temporal-spatial parameters and kinematics of walking in both healthy participants and persons with spinal cord injury (SCI) using three-dimensional motion analysis to facilitate further development of such devices. Kinematics and temporal spatial ...
Starks Tyrel J - - 2013
Previous research has found secure adult attachment to be associated positively with dimensions of main partner relationship quality and negatively with sexual risk taking and sex with casual partners among heterosexuals in primary relationships. Potential associations between adult attachment and aspects of relationship functioning have received limited attention among gay ...
Fatica Alessandro A Department of Biology and Biotechnology "Charles Darwin", Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, - - 2014
Genomes of multicellular organisms are characterized by the pervasive expression of different types of non-coding RNAs (ncRNAs). Long ncRNAs (lncRNAs) belong to a novel heterogeneous class of ncRNAs that includes thousands of different species. lncRNAs have crucial roles in gene expression control during both developmental and differentiation processes, and the ...
Mackay Trudy F C TF Department of Biological Sciences, Campus Box 7614, North Carolina State University, Raleigh, North Carolina 27695-7614, - - 2014
The role of epistasis in the genetic architecture of quantitative traits is controversial, despite the biological plausibility that nonlinear molecular interactions underpin the genotype-phenotype map. This controversy arises because most genetic variation for quantitative traits is additive. However, additive variance is consistent with pervasive epistasis. In this Review, I discuss ...
Naccarato Mark - - 2013
Therapy for HIV often can make pharmacologic management of comorbidities challenging since many antiretroviral agents significantly modulate drug metabolism pathways. Amiodarone is commonly used to control cardiac arrhythmias; however, it is recognized as having a narrow therapeutic window with potential for significant drug toxicity. Amiodarone is metabolized by CYP3A4, CYP2C8 ...
Saneja Ankit - - 2013
Introduction: P-glycoprotein (P-gp) is a multi-specific efflux transporter belonging to ATP-binding cassette (ABC) transporter family, encoded by the ABCB1 gene, which significantly impacts the pharmacokinetics as well as multidrug resistance of anticancer drugs. Areas covered: This review explores how human P-gp transporters modulate the pharmacokinetics of anticancer drugs and emerging ...
Li Yuanyuan - - 2013
Significant alteration in the microbial community can occur across reclamation areas suffering subsidence from mining. A reclamation site undergoing fertilization practices and an adjacent coal-excavated subsidence site (sites A and B, respectively) were examined to characterize bacterial diversity using 454 high-throughput 16S rDNA sequencing. The dominant taxonomic groups in both ...
Satomura Yoshihiro - - 2013
Recently, there has been growing emphasis on enhancing subjective quality of life (QOL), in addition to treating symptoms or extending one's life. However, the neurobiological basis of subjective QOL is unknown. To illuminate the neural substrates that inform subjective QOL, the association between prefrontal function and subjective QOL was explored ...
de Barros André Luís Branco - - 2013
Atherosclerosis is a leading cause of death in industrialized countries and is characterized by the accumulation of lipids and inflammatory cells, including macrophages, in blood vessel walls. Therefore, the ability to image macrophages could help identify plaques that are precursors of acute thrombotic events. Previous research has shown that long-circulating ...
Yiyenoğlu Ozgür Bilgin - - 2013
To determine the levels of oxidative stress markers in recurrent pregnancy loss using a novel automated method. 30 pregnant women in their first trimester with a history of recurrent pregnancy loss (RPL) and 30 healthy pregnant women were enrolled in this prospective controlled study. Total antioxidant capacity (TAC), total oxidant ...
Bach Trond - - 2013
We found previously that stimulation of natriuretic peptide receptor (NPR)-B by C-type natriuretic peptide (CNP) in failing rat ventricle potentiates β1-adrenoceptor (β1-AR)-mediated inotropic response to noradrenaline through cGMP-mediated inhibition of phosphodiesterase (PDE) 3, thereby enhancing cAMP-mediated signalling. Increased cAMP-mediated signalling is deleterious in chronic heart failure (HF; basis for the ...
Hušek J - - 2013
Natal dispersal allows individuals to reach suitable breeding sites. The effect of present plant phenology as a cue for dispersal into areas with favourable stages of development has been well established across avian and mammalian taxa. However, the effect of past experience is less understood. We studied the effect of ...
Manoharan Gunasekar - - 2013
A multitude of plants have been used extensively for the treatment of cancers throughout the world. The protein, α, β momorcharin has been extracted from the plant Momordica charantia (MC), and it possesses anti-cancer and anti-HIV properties similar to the crude water and methanol soluble extract of the plant. This ...
Feng Miao - - 2013
To realize their practical and operable applications as a potential optical limiting (OL) material, quantum dots (QDs) need to have good processability by incorporating them into optical-quality matrices. This work reports a facile route for the room-temperature preparation of large, stable transparent monolithic CdS nanocomposites which can be easily extended ...
Kuhrt Katy - - 2013
Abstract Objective Accurate prediction of spontaneous preterm birth (sPTB) is essential to target interventions. Fetal fibronectin (fFN) is a leading predictor. A quantitative fFN (qfFN) test has improved prediction, based on high vaginal swabs (HVS). It is not known how endocervical (ECS) fFN levels compare, or which has the best ...
Chen J Q - - 2013
This study aimed to analyze the expression, clinical significance of cyclin G2 (CCNG2) in esophageal carcinoma, and the biological effect in its cell line by CCNG2 overexpression. Immunohistochemistry and western blot were used to analyze CCNG2 protein expression in 73 cases of esophageal cancer and normal tissues to study the ...
Jain Amit K - - 2013
The present work reports rationalized development and characterization of solidified self-nanoemulsifying drug delivery system for oral delivery of combinatorial (tamoxifen and quercetin) therapeutic regimen. Suitable oil for the preparation of liquid SNEDDS was selected based on the maximum saturation solubility of both the drugs while surfactant and co-surfactant were selected ...
Miltonprabu S - - 2013
Abstract The present investigation was aimed to investigate the possible protective role of Diallyl trisulfide (DATS) against Arsenic (As) induced hepatic mitochondrial toxicity in rats. Mitochondria were isolated from the liver tissue of rats from all the groups. Lipid profile, lipid peroxidation, antioxidant enzyme activities, hepatic function enzymes, mitochondrial swelling, ...
Luhtanen Anne-Mari - - 2013
In search for sea ice bacteria and their phages from the Baltic Sea ice, two ice samples were collected from land-fast ice in a south-west Finland coastal site in February and March 2011. Bacteria were isolated from the melted sea ice samples and phages were screened from the same samples ...
Yang Peiguo - - 2013
Autophagy involves the sequestration of a portion of the cytosolic contents in an enclosed double-membrane autophagosomal structure and its subsequent delivery to lysosomes for degradation. Autophagy activity functions in multiple biological processes during Caenorhabditis elegans development. The basal level of autophagy in embryos removes aggregate-prone proteins, paternal mitochondria and spermatid-specific ...
Rydberg Patrik - - 2013
Introduction: The cytochrome P450 enzymes (CYPs) metabolize many drug compounds. They catalyze a wide variety of reactions, and potentially, a large number of different metabolites can be generated. Density functional theory (DFT) has, over the past decade, been shown to be a powerful tool to rationalize and predict the possible ...
Tagliafico Alberto - - 2013
The aim of this review is to illustrate the spectrum of ultrasound-guided procedures around the shoulder. The shoulder is affected by a wide range of both, traumatic and degenerative diseases. Ultrasound guidance is a low-cost and safe tool to perform minimally invasive interventional procedures around the shoulder. The clinical outcome ...
Liao Kang-Ling - - 2013
We consider a two-patch model for a single species with dispersal and time delay. For some explicit range of dispersal rates, we show that there exists a critical value τ c for the time delay τ such that the unique positive equilibrium of the system is locally asymptotically stable for ...
Hu Ying - - 2013
There is a lack of information on the interactive relationship of absorption and transformation between two inorganic arsenic (As) species and two inorganic selenium (Se) species in rice grown under hydroponic condition. Interactive effects of inorganic As (As(III)) and (As(V)) and Se (Se(IV)and Se(VI)) species on their uptake, accumulation, and ...
Behbahani Mohammad - - 2013
A simple, rapid, and efficient sample pretreatment technique, based on solvent-based de-emulsification dispersive liquid-liquid microextraction (SD-DLLME), followed by high performance liquid chromatography (HPLC) has been developed for simultaneous preconcentration and trace detection of 2,4-dichlorophenoxyacetic acid (2,4-D) and 2-methyl-4-chlorophenoxyacetic acid (MCPA) in water and urine samples. Some parameters such as acidity ...
Jokela M - - 2013
The hypothesis of metabolically healthy obesity posits that adverse health effects of obesity are largely avoided when obesity is accompanied by a favorable metabolic profile. We tested this hypothesis with depressive symptoms as the outcome using cross-sectional data on obesity, metabolic health and depressive symptoms. Data were extracted from eight ...
Zhang Hua - - 2013
In this study, metagenomic DNA was screened for the Na(+)/H(+) antiporter gene from the halophilic bacteria in Daban Salt Lake by selection in Escherichia coli KNabc lacking three major Na(+)/H(+) antiporters. One gene designated as Hb_nhaD encoding a novel NhaD-type Na(+)/H(+) antiporter was finally cloned. The presence of Hb_NhaD conferred ...
Karaman Maja - - 2013
Abstract Crude extracts of two edible and two medicinal lignicolous mushroom species: Meripilus giganteus, Agrocybe aegerita, Fomes fomentarius and Xylaria polymorpha, growing wild in Serbia, were analyzed for their antioxidative and antibacterial potentials. Free radical scavenging capacity (RSC) on DPPH(•) and (•)OH was evaluated both by spectrophotometer and by Electron ...
Mygatt J - - 2013
Background:To determine whether prostate cancers detected in the anterior vs posterior zones impact clinicopathological features and patient outcomes. This information could potentially affect clinical management.Methods:A retrospective pathological review of 1528 radical prostatectomy specimens submitted between 1989 and 2011 was completed. Specimens were characterized as anterior zone vs posterior zone based ...
Estevez Ana - - 2013
Pathological gambling has severe consequences for adolescents and their families and friends. Despite its high prevalence, pathological gambling in adolescents has been insufficiently studied. Sensation seeking and impulsivity are two variables that are related to the appearance and maintenance of pathological gambling. However, few studies have determined the role these ...
D'Arco Felice - - 2013
Neurofibromatosis type 1 (NF1) is a multisystem autosomal dominant disorder that primarily involves the skin and the nervous system. Development of cerebral arterial stenosis is a potentially deadly complication of NF1, which is frequently underestimated. The aim of our paper is to report the frequency of this cerebrovascular disease in ...
Cazzola Mario - - 2013
Introduction: Indacaterol is a β2-agonist with a rapid onset of action and a bronchodilating effect that lasts for 24 h. Areas covered: This review considers indacaterol in chronic obstructive pulmonary disease patients, in whom it is rapidly absorbed into the systemic circulation with serum levels measurable after 5 min and ...
Sautner Judith - - 2013
Gout is the most common inflammatory joint disease in the Western world, with increasing prevalence. Like former 3e-initiatives (Experts-Evidence-Education) dealing with other rheumatological problems, this initiative aimed at the development of international recommendations for the diagnosis and management of gout and hyperuricemia based on a systematic literature research. In the ...
Liu Ruiyu - - 2013
Limb-length discrepancy (LLD) arising from hip subluxation or dislocation and accompanied by insufficiency of hip abductor in patients with developmental dysplasia of the hip (DDH) can be corrected partially or completely with total hip arthroplasty (THA). However, information about post-THA changes in abductor strength related to preoperative LLD in patients ...
Sandrone Stefano - - 2013
This Journal Club article looks at a study by Tessitore et al.,(1) who investigated functional connectivity (FC) within the default-mode network (DMN) in cognitively unimpaired patients with Parkinson disease (PD). PD is the second most common neurodegenerative disorder after Alzheimer disease (AD) and is expected to become progressively more prevalent ...
Zheng Yan-Zhen - - 2013
There has been a rapid expansion in the use of molecular magnets for both low- and ultra low-temperature cooling applications in recent years, and here we review the chemical variation and magnetothermal properties of reported molecular coolers, structuring the review by structural dimensions, metal-ions involved and ligands employed. This review ...
Omori Takeshi - - 2013
The intracorporeal anastomosis is one of the most difficult procedures in single-incision laparoscopic gastrectomy for gastric cancer. We describe a simple technique for intracorporeal triangular Billroth I anastomosis in transumbilical single-port surgery. After adequate lymphadenectomy, the stomach and duodenum were staple-transected. Small incisions were made to the remnant stomach and ...
Haynes Aveni - - 2013
The aim of this study was to investigate the association between maternal smoking during pregnancy and type 1 diabetes in the offspring, using complete population data sources available in Western Australia. A prospective cohort study was undertaken with cases defined as children born in Western Australia between 1998 and 2008 ...
Krishna Vidya - - 2013
Streptococcal Toxic Shock syndrome (STSS) is a serious complication caused by exotoxins of Group A Streptococcus (GAS). It presents with fulminant shock and rash, is rapidly progressive with Multi-Organ Dysfunction Syndrome (MODS) and requires aggressive therapy with fluids, antibiotics and source control.
Clarke Ian C - - 2013
Concerns have been raised about the sequelae of metal-on-metal (MoM) bearings in total hip arthroplasty (THA). However, retrieval studies, which offer the best insight into the clinically relevant mechanisms of MoM wear, have followed predictable trends to date such as indicting cobalt-chromium (CoCr) metallurgy, cup design, high conformity between the ...
Bultink I E M - - 2013
The incidence of clinical fractures and the associated factors were assessed in patients with systemic lupus erythematosus (SLE) versus matched controls. We found an increased fracture risk in SLE patients compared to controls. Glucocorticoid use, longer disease duration, neuropsychiatric disease complications and previous osteoporotic fractures were identified as associated factors. ...
Linda Anna - - 2013
This study was undertaken to evaluate whether magnetic resonance (MR) imaging is able to rule out malignancy in the case of BI-RADS 3 microcalcifications, providing a sufficient negative predictive value (NPV) for early work-up, and to reduce unnecessary stereotactically guided vacuum-assisted biopsy (SVAB) procedures. We prospectively enrolled consecutive women with ...
Valentini Anna Lia - - 2013
To verify whether the capability of magnetic resonance imaging (MRI) in diagnosing deep infiltrating colorectal endometriosis (DICE) is improved using an association of MRI findings. The imaging database of our Institute of Radiology was retrospectively reviewed to identify patients subjected to MRI for a suspicion of deep infiltrating endometriosis. Medical ...
Zhao Yue - - 2013
A family of silver(i) complexes, [Ag2(L)2(OOCCF3)2] (), [Ag(L)0.5(OOCCF3)] (), [Ag(L)2](OOCCF3)(H2O)2 (), was obtained by reactions of 4,4'-di(2-oxazolinyl)biphenyl (L) and AgOOCCF3 in different reaction media. Compound has a 1D chain structure with alternative connections between the Ag(i) and L ligand. When the crystal nucleation inductor, pyrazine, was added into the reaction ...
Giribabu Lingamallu - - 2013
'Axial-bonding'-type hetero trimers have been constructed by employing a simple 'inorganic' reaction such as axial bond formation of main group element containing phosphorus corrole. The approach is simple and modular in nature. The architecture of these hetero trimers such that, while a phosphorus(V)corrole forms the basal scaffolding unit, either two ...
Todorova Roumiana - - 2013
Ewing`s sarcoma (ES) family of tumors (ESFTs) are round cell tumors of bone and soft tissues, afflicting children and young adults. This review summarizes the present findings about ES cancer stem cell (CSC) targeted therapy: prognostic factors, chromosomal translocations, initiation, epigenetic mechanisms, candidate cell of ES origin (Mesenchymal stem cells ...
Ramasamy Thiruganesh - - 2013
To investigate the effect of polyelectrolytes on the formation and physicochemical properties of chitosan nanoparticles (CS-NPs) used for the delivery of an anticancer drug, doxorubicin (DOX). Three DOX-loaded CS-NPs were formulated with tripolyphosphate (CS-TP/DOX NPs), dextran sulfate (CS-DS/DOX NPs), and hyaluronic acid (CS-HA/DOX NPs) by using ionotropic gelation or complex ...
Kupiainen-Määttä Oona - - 2013
Quantum chemical calculations have been performed on negatively charged nitric acid - sulfuric acid - dimethylamine clusters. The cluster energies were combined with a kinetic model to study the chemical ionization of sulfuric acid molecules and sulfuric acid - dimethylamine clusters with nitrate ions. Both the sulfuric acid monomer and ...
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