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Kochman Janusz - - 2013
Amount of data comparing intravascular ultrasound (IVUS) and optical coherence tomography (OCT) for the detection of stent coverage in clinical settings is limited. The objective of this study was a qualitative and quantitative assessment of the vascular healing patterns in patients after stent implantations visualized by both IVUS and OCT. ...
Sada Ken-Ei - - 2013
Objective. We conducted a cross-sectional nationwide survey to determine eosinophilic granulomatosis with polyangiitis (Churg-Strauss) (EGPA) prevalence and clinical features in Japan. Methods. Data for EGPA patients in 2008 were collected from 1,564 hospitals. In total, 965 patients were reported from 365 departments. In a second survey, clinical data for 473 ...
Shen Jie - - 2013
The present paper describes a new method for manufacturing large scale, stable, transportable and designable nanostructured porous TiO2 tapes on various substrates for use in photoelectrochemical cells. The method involves pre-deposition of TiO2 strips on the fluorine doped tin oxide (FTO) glass by screen-printing method, peeling off TiO2 strips from ...
Ferracci Valerio - - 2013
The kinetics of the atmospherically important gas phase radical reaction between BrO and ClO have been studied over the temperature range T = 246-314 K by means of laser flash photolysis coupled with UV absorption spectroscopy. Charge-coupled-device (CCD) detection allowed simultaneous monitoring of both free radicals and the OClO product ...
Vin-Raviv Neomi - - 2013
ABSTRACT Background: Several studies have suggested that post-traumatic stress disorder (PTSD) is related to adverse health outcomes. There are limited data on PTSD and cancer, which has a long latency period. We investigated the association between World War II (WWII)-related PTSD and subsequent breast cancer (BC) risk among Jewish WWII ...
Miest Tanner S TS 1] Department of Molecular Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA. [2] Virology and Gene Therapy Track, Mayo Graduate School, Rochester, Minnesota 55905, - - 2014
Early-stage clinical trials of oncolytic virotherapy have reported the safety of several virus platforms, and viruses from three families have progressed to advanced efficacy trials. In addition, preclinical studies have established proof-of-principle for many new genetic engineering strategies. Thus, the virotherapy field now has available a diverse collection of viruses ...
Jaguszewski Milosz - - 2013
Recently, it has been suggested that the type of stent used in primary percutaneous coronary interventions (pPCI) might impact on outcomes of patients with acute myocardial infarction (AMI). Indeed, drug-eluting stents (DES) reduce neointimal hyperplasia when compared to bare-metal stents (BMS); moreover the later generation DES due to its biocompatible ...
Lynch M - - 2013
Propranolol is an effective, safe treatment for complicated infantile haemangiomas (IH). We evaluated all patients (n = 44) with IH treated with propranolol in our department. Of the 44 patients who were begun on propranolol therapy, 26 patients have completed the treatment to date and all had a good response. The mean ...
Yoshimi Ryusuke - - 2013
Objectives. To determine whether ultrasonography (US) predicts Boolean remission in rheumatoid arthritis (RA) patients who had achieved disease activity score in 28 joints (DAS28)-based remission criteria. Methods. Thirty-one RA patients in DAS28-based clinical remission were recruited. US semiquantitatively determined Gray scale (GS) and power Doppler (PD) signal scores in the ...
Zheng Xian Hu - - 2013
Abstract The complete mitochondrial genome of Saurogobio dabryi is 16,604 bp in length with 55.88% AT content, including 13 protein-coding genes, 22 tRNA genes, 2 rRNA genes, and 1 control region. The termination-associated sequence and six conserved sequence blocks were also identified. Compared all protein-coding genes and whole genome sequence with ...
Angeli R D - - 2013
Background: The tensor tympani muscle is the largest muscle within the middle ear. Its voluntary contraction is a very unusual event. Only a few papers have documented its audiometric effects. Objective: To report an unusual case of voluntary tensor tympani muscle contraction and describe its audiometric effects. Case report: A ...
Jarrett Oo - - 2013
To establish normal reference values for penile size in Nigerian newborn boys and to compare those values with standards from other populations METHODS: A total number of 261 healthy newborn boys delivered at gestational ages of 28 weeks or more were enrolled in the study. Penile lengths and widths were ...
Wang Fu-Rong - - 2013
Iron deficiency anemia (IDA) is the one of the most common nutritional problems and is encountered all over the world. This study analysed the effects of squid ink melanin-Fe (SM-Fe) on IDA in rats. Forty weanling SD male rats were used and thirty-two rats were fed an iron-deficient diet for ...
Gupta Sahil - - 2013
Introduction: Natalizumab is a highly effective monoclonal antibody used for the treatment of multiple sclerosis (MS). It reduces relapses, delays the onset of disease progression and improves disease outcomes in relapsing-remitting MS. However, treatment with natalizumab is associated with progressive multifocal leukoencephalopathy (PML), a severe opportunistic brain infection with John ...
Zhu Leize - - 2013
Earth-abundant and nontoxic pyrite iron disulfide (FeS2) is very promising for photovoltaic applications but the phase purity and the morphology of iron pyrite nanocrystals (NCs) have a significant impact on the solar cell performance. In this work, we systematically investigated reaction conditions and the local chemical environment on the phase ...
Suárez Dimas - - 2013
Computational methods can help in the design of new bioorganometallic compounds. However, the presence of multihapto or σ/π metal-ligand bonding still precludes the direct application of either pure molecular mechanics (MM) or hybrid quantum mechanics-MM methods to study the flexibility of biomolecules in complex with organometallics. Herein, we present a ...
Ramakrishnan Sathish Kumar - - 2013
Engineering shape-controlled bionanomaterials requires comprehensive understanding of interactions between biomolecules and inorganic surfaces. We explore the origin of facet-selective binding of peptides' adsorbed onto Pt(100) and Pt(111) crystallographic facets. Using molecular dynamics simulations we show that upon adsorption the peptides adopt a predictable conformation. We compute the binding energies of ...
Ishibashi Akira - - 2013
A novel free radical scavenger, edaravone, has been demonstrated to exert a neuroprotective effect and improve outcomes in acute ischemic stroke, but there have been few clinical studies. Therefore, we investigated retrospectively whether the administration of edaravone at the acute stage of ischemic stroke can improve outcomes of the disease ...
Pietrzak R H - - 2013
Post-traumatic stress disorder (PTSD) in response to the World Trade Center (WTC) disaster of 11 September 2001 (9/11) is one of the most prevalent and persistent health conditions among both professional (e.g. police) and non-traditional (e.g. construction worker) WTC responders, even several years after 9/11. However, little is known about ...
Khan Arif - - 2013
Buccal midazolam has emerged as an effective alternative to rectal diazepam in the management of paediatric status epilepticus. This study aimed to identify carers' views on the safety, efficacy and acceptability of buccal midazolam in the management of this common neurological emergency. Community-based, face-to-face interviews were carried out with 34 ...
Boumans Nicolle P G - - 2013
This study compared the work-related experiences and personal health status of double-duty caregivers with those of caregivers who do not provide informal care to a family member or close friend in need. The interest in providing informal care alongside employment is growing. However, little attention has been paid to the ...
Orwat Stefan - - 2013
Left ventricular longitudinal strain and strain rate (SR) are sensitive markers of early systolic dysfunction. We aimed to evaluate the feasibility of a novel, cardiac magnetic resonance (CMR) based method (feature tracking, FT) for the assessment of strain and SR and to compare the CMR based results to those obtained ...
Dinu Sorin - - 2013
Corynebacterium diphtheriae is the etiological agent of diphtheria, a potential fatal disease caused by a corynephage toxin. The expression of this diphtheria toxin is controlled via an iron-dependent repressor with various functions (DtxR). Some mutations in the dtxR gene are associated with diminished activity or even with total loss of ...
Suhoyo Yoyo - - 2013
Context: Cultural differences between countries may entail differences in feedback processes. Aims: By replicating a Dutch study in Indonesia, we analysed whether differences in processes influenced the perceived instructiveness of feedback. Methods: Over a two-week period, Indonesian students (n = 215) recorded feedback moments during clerkships, noting who provided the feedback, whether ...
Piñeiro Zulema - - 2013
A new method for fast determination of stilbenoids from grape stems was developed. Ultrasound-assisted extraction was applied prior to chromatographic determination of stilbenoids in the extracts and the stability of stilbenoids under extraction conditions was checked. A fractional experimental design was developed to analyze the influence on the extraction process ...
Nobili Stefania - - 2013
ABSTRACT About 60% of diffuse large B cell lymphoma (DLBCL) patients may be cured by primary chemotherapy with an R-CHOP regimen. Most of the remaining will die of the disease, mainly because of occurrence of tumour drug resistance. Many efforts have been made to explain the molecular mechanisms of drug ...
Dai Kai - - 2013
Surface-fluorinated TiO2 (F-TiO2) nanosheets with exposed (001) facets were synthesized from a scalable hydrothermal treatment assisted by a specific stabilization effect of fluorine ions on the (001) facets. Assembly of F-TiO2 on graphene oxide (GO) sheets into GO/F-TiO2 hybrid in aqueous solution was further achieved by making use of the ...
Kumar Ashok - - 2013
A long standing problem related to the capping of carbon nanotubes (CNT) by inorganic materials at high temperature has been solved. In situ dynamic response of Pb(Zr0.52Ti0.48)O3 (PZT) nanocrystals attached to the wings of the outer surface of PZT/CNT hybrid-nanostructure has been demonstrated under a constant-energy high-resolution transmission electron microscopy ...
Wang Xiao-Mi - - 2013
Many studies have examined pair-wise interactions between plants and endophytes, while overlooking the interplays among multiple endosymbionts and their combined impacts on hosts. In this study, Atractylodes lancea plantlets were inoculated with endophytic fungus Acremonium strictum AL16, or endophytic bacterium Acinetobacter sp., or both, to investigate the impacts of the ...
Qiao Na - - 2013
Increase of belowground C allocation by plants under global warming or elevated CO2 may promote decomposition of soil organic carbon (SOC) by priming and strongly affects SOC dynamics. The specific effects by priming of SOC depend on the amount and frequency of C inputs. Most previous priming studies have investigated ...
Chiu Yen-Ling - - 2013
The ability of individual T cells to perform multiple effector functions is crucial for protective immunity against viruses and cancer. This polyfunctionality is frequently lost during chronic infections; however, the molecular mechanisms driving T cell polyfunctionality are poorly understood. We found that human T cells stimulated by a high concentration ...
Yip Henry K - - 2013
The vertebrate retina is a well-characterized model for studying neurogenesis. Retinal neurons and glia are generated in a conserved order from a pool of mutlipotent progenitor cells. During retinal development, retinal stem/progenitor cells (RPC) change their competency over time under the influence of intrinsic (such as transcriptional factors) and extrinsic ...
Smith J R - - 2013
The HSP90 molecular chaperone plays a key role in the maturation, stability and activation of its clients, including many oncogenic proteins. Kinases are a substantial and important subset of clients requiring the key cochaperone CDC37. We sought an improved understanding of protein kinase chaperoning by CDC37 in cancer cells. CDC37 ...
Arantes Lucas Micquéias - - 2013
The aim of this work was to study the interaction between the local anesthetic benzocaine and p-sulfonic acid calix[n]arenes using NMR and theoretical calculations and to assess the effects of complexation on cytotoxicity of benzocaine. The architectures of the complexes were proposed according to (1) H NMR data (Job plot, ...
Venkatesan Swaminathan - - 2013
Charge transport and bimolecular recombination dynamics were correlated with nanomorphology in polymer solar cells. The morphology of poly(diketopyrrolopyrrole-terthiophene) (PDPP3T) and phenyl-C61-butyric acid methyl ester (PC60BM) blend films was modified using different solvent additives namely 1-chloronaphthalene (CN), 1,8-diiodooctane (DIO) and 1,8-octanedithiol (ODT) and their role on steady state and transient optoelectronic ...
Labs Sabrina - - 2013
The miscibility behavior of the USiO<sub>4</sub> - ThSiO<sub>4</sub> system was investigated. The end members and ten solid solutions U<sub>x</sub>Th<sub>(1-x)</sub>SiO<sub>4</sub> with x = 0.12 - 0.92 were successfully synthesized, without formation of other secondary uranium or thorium phases. Lattice parameters of the solid solutions evidently follow Vegard's Law. Investigation of the ...
Kim Daejin - - 2013
Exceptionally high hydrogen permselectivity, exceeding that of any polymeric or porous inorganic systems, is achieved using an ionically crosslinked multilayer polymer thin film.
Sheehan Frances T FT Functional and Applied Biomechanics Section, Rehabilitation Medicine Department, National Institutes of Health, Bethesda, MD, USA. Electronic address: - - 2014
Obstetrical brachial plexus palsy (OBPP) is a common birth injury, resulting in severe functional losses. Yet, little is known about how OBPP affects the 3-dimensional (3D) humeral morphology. Thus, the purpose of this study was to measure the 3D humeral architecture in children with unilateral OBPP. Thirteen individuals (4 female ...
Morcos Peter N - - 2013
Background: Danoprevir is a potent, highly selective, macrocyclic, orally bioavailable inhibitor of the hepatitis C virus protease, and a substrate of cytochrome P450 (CYP) 3A. It is co-administered with low-dose ritonavir, a potent CYP3A inhibitor, to enhance danoprevir pharmacokinetics. Ketoconazole is a substrate for and potent selective inhibitor of CYP3A. ...
Newbold A - - 2013
Following the establishment of histone deacetylases (HDACs) as promising therapeutic targets for the reversal of aberrant epigenetic states associated with cancer, the development of HDAC inhibitors (HDACi) and their underlying mechanisms of action has been a significant area of scientific interest. HDACi induce diverse biological responses including the inhibition of ...
Glenn S T - - 2013
Efforts to model human pancreatic neuroendocrine tumors (PanNETs) in animals have been moderately successful, with minimal evidence for glucagonomas or metastatic spread. The renin gene, although classically associated with expression in the kidney, is also expressed in many other extrarenal tissues including the pancreas. To induce tumorigenesis within rennin-specific tissues, ...
Trosko James E - - 2013
This article as designed to examine whether the "stoichiometric" or "elite models" of the origin of the "induced pluripotent stem" (iPS) cells fits some experiment facts from the developmental biology of adult stem cells and from the field of cancer research. In brief, since the evidence presented to support the ...
Rossbach Kristine - - 2013
Various mediators are involved in the induction of itch, i.e. pruritus; however, the in vivo pharmacology of pruritus seems to be different in distinct species, and little is known about receptors that are involved in the induction of itch in dogs. The species differences in the mediation of pruritus might ...
Jo Mi Ru - - 2013
A nano-Si/FeSi2Ti hetero-structure has been synthesized for highly reversible Li-ion batteries by using a simple melt-spinning method. We demonstrate that this composite has a very peculiar core/shell structure in which the FeSi2Ti alloy plays various pivotal roles as a mechanically supporting backbone and as an electronic pathway for the active ...
Demirci Serpil - - 2013
6-Substituted amino-penicillanic acid esters were synthesized starting with 6-apa. The compounds containing a 1,3-thiazole- or 1,3-thiazolidinone nucleus linked to the penicillanic acid skeleton via a hydrazino linkage were obtained from 6-apa. The treatment of carbonylamino and carbonothioylamino compounds with 4-chlorophenacyl bromide or ethyl bromoacetate gave 6-bis{4-[1,3-thiazol(idinone)amino]benzoyl}amino derivatives of 6-apa. Benzyl ...
El-Sayed Yasser S - - 2013
Fish are relatively sensitive to changes in their surrounding environment, including increasing pollution. Therefore, the present study was undertaken to evaluate the impact of contamination with the pendimethalin-based herbicide; Stomp(®) 50% EC (50% pendimethalin as emulsive concentrate) on adults of the monosex Nile tilapia Oreochromis niloticus L. A total of ...
Bartels Stephen J - - 2013
OBJECTIVES Self-management is promoted as a strategy for improving outcomes for serious mental illness as well as for chronic general medical conditions. This study evaluated the feasibility and effectiveness of an eight-month program combining training in self-management for both psychiatric and general medical illness, including embedded nurse care management. METHODS ...
Kumar Sudershan - - 2013
Objectives: To demonstrate the bioequivalence between the test and reference formulations of losartan/hydrochlorothiazide 50 + 12.5 mg tablet and evaluate the effect of ethnicity on pharmacokinetics properties of losartan, losartan carboxylic acid and hydrochlorothiazide on healthy Asian Indian and Japanese volunteers. Methods: Randomized, open-label, crossover, bioavailability studies were conducted separately ...
Helal Mohamed H M - - 2013
In an attempt to find a new class of antioxidant agents, a series of pyrazole, pyridopyrazoltriazine, pyrazolotriazine, isoxazole, and pyridine-containing products were prepared, starting with curcumin and appropriate chemical reagents. Thus, curcumin 1 undergoes coupling reaction with diazonium salts 2-5 to afford the corresponding 4-arylazo derivatives 6-9. Heating of 6 ...
Kang Z - - 2013
Agents targeting the insulin-like growth factor-1 receptor (IGF1R) are in clinical development, but, despite some initial success of single agents in sarcoma, response rates are low with brief durations. Thus, it is important to identify markers predictive of response, to understand mechanisms of resistance, and to explore combination therapies. In ...
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