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Strand H - - 2013
To compare attitudes towards Kangaroo Mother Care (KMC) among staff in two high-tech neonatal intensive care units, which provided parents with different opportunities to get involved in their infants' care. Questionnaires were completed by healthcare staff in Unit A, which provided parents with unrestricted access so that they could provide ...
Yu Allen C S - - 2013
A novel bacterial growth monitoring method using a tunable resistive pulse sensor (TRPS) system is introduced in this study for accurate and sensitive measurement of cell size and cell concentration simultaneously. Two model bacterial strains, Bacillus subtilis str.168 (BSU168) and Escherichia coli str.DH5α (DH5α), were chosen for benchmarking the growth-monitoring ...
Mays Charles E - - 2013
Cellular prion protein (PrP(C) ) misfolds to infectivity-associated PrP(S) (c) and generates carboxyl-terminal fragments C1 and C2 in healthy and prion-infected animals. C1 cleavage occurs amino-terminal of PrP(C) 's hydrophobic domain, while the larger C2 fragment is generated by cleavage at the end of the octarepeat region. Since the PrP-like ...
Gohil Ishan - - 2013
Vacuum phenomenon (VP) is an anatomical entity of potential confusion in the diagnosis and evaluation of joint pathology. Observation of this phenomenon has been demonstrated on basic radiographs, computed tomography, and magnetic resonance imaging. Although VP is most often associated with degenerative joint disease, it is observed with other pathologies. ...
Brumback Babette A - - 2013
Much attention has been paid to estimating the causal effect of adherence to a randomized protocol using instrumental variables to adjust for unmeasured confounding. Researchers tend to use the instrumental variable within one of the three main frameworks: regression with an endogenous variable, principal stratification, or structural-nested modeling. We found ...
Tuckett Joel - - 2013
Background Sialocele and salivary fistula are common complications after parotidectomy. The purpose of the present study was to investigate whether extent of parotidectomy influences the incidence of these complications. Methods Prospective study of 66 consecutive parotidectomies. Cases undergoing skin or bone resection or flap reconstruction were excluded. Patients were divided ...
Kobayashi Kyo - - 2013
Abstract Medical-grade collagen peptide is used as an additive agent in pharmaceutical formulations; however, it is unknown as to whether the compound exerts antioxidant effects in vitro. In this study, we evaluated the antioxidant effects of medical-grade collagen peptide on reactive oxygen species such as hydroxyl radical, superoxide anion radical ...
Imaizumi Yoichi - - 2013
Human induced pluripotent stem (iPS) cells obtained by reprogramming technology are a source of great hope, not only in terms of applications in regenerative medicine, such as cell transplantation therapy, but also for modeling human diseases and new drug development. In particular, the production of iPS cells from the somatic ...
Fisher Oriana S - - 2013
Cerebral cavernous malformations (CCM) are neurovascular dysplasias that result in mulberry-shaped lesions predominantly located in brain and spinal tissues. Mutations in three genes are associated with CCM. These genes encode for the proteins KRIT1/CCM1 (krev interaction trapped 1/cerebral cavernous malformations 1), cerebral cavernous malformations 2, osmosensing scaffold for MEKK3 (CCM2/malcavernin/OSM), ...
Jiang Jingjing - - 2013
Microwave absorption properties of core double-shell FeCo/C/(x)BaTiO3 nanocomposites were investigated in the 1-18 GHz frequency range. High resolution transmission electron microscopy studies reveal the core double-shell type nanocomposite with FeCo nanoparticles as the center, while carbon and BaTiO3 are the inside and the outside shells, respectively. Enhanced relative permittivity made ...
Zubrow Marc T - - 2013
Because of concerns for propagating clots into pulmonary emboli by the placement of pneumatic compression boots (PCBs), the standard of care at our institution was to perform a duplex Doppler ultrasound with compression (DUSC) before applying PCBs. We sought to determine the rate of asymptomatic preexisting deep vein thrombosis (DVT) ...
Lim Ratana - - 2013
Inflammation is associated with preterm birth, a worldwide healthcare issue. SLIT3 has a role in inflammation, and thus, the purpose of this study was to determine the effect of SLIT3 on labour mediators in human gestational tissues. SLIT3 protein expression was performed using immunohistochemistry in foetal membranes and myometrium with ...
Chan Jason Y K - - 2013
Background To evaluate the current use of transoral robotic surgery (TORS) in the treatment of parapharyngeal space (PPS) neoplasms through a case series and systematic analysis Methods A case series review of 4 patients combined with a PubMed, Web of Science, and Scopus search that identified 82 reports. Fifty-three papers ...
Abate Antonio - - 2013
Ionizing chemical dopants are widely used in organic semiconductors to enhance the charge transport properties by increasing the number of mobile charge carriers. However, together with mobile charges, chemical doping produces anion-cation pairs in the organic matrix. In this work we use experimental and computational analysis to study the influence ...
Oldenburg J - - 2013
Warfarin and other 4-hydroxycoumarin-based oral anticoagulants targeting vitamin K 2,3-epoxide reductase complex subunit 1 (VKORC1) are administered to humans, mice and rats with different purposes in mind - to act as pesticides in high-dosage baits for killing rodents, but also to save lives when administered in low dosages as antithrombotic ...
Dyer Kerry - - 2013
Abstract Purpose: Research indicates that although 50-60% of people who have had a traumatic brain injury (TBI) experience changes in sexual functioning, sexuality issues remain largely unaddressed in rehabilitation. This study aimed to explore rehabilitation professionals' perceptions and experiences of discussing sexuality with service-users who have had a TBI. Method: ...
Gendreau Anne - - 2013
Abstract Purpose: Rehabilitation professionals and researchers underscore the impact of an acquired disability on identity. However, the cognitive process by which identity is transformed is understudied. The present study aims to explore the cognitive process by which personal identity is reconstructed following disability onset. Methods: A template organizing style of ...
Loll-Krippleber Raphaël - - 2013
In response to genotoxic stress (GS), Candida albicans can undergo polarized growth and massive genome rearrangements including loss-of-heterozygosity (LOH) events. We evaluated the contribution of the CaRad53p and CaDun1p kinases of the DNA damage checkpoint (DDCP) in these processes. Characterization of C. albicans rad53ΔΔ and dun1ΔΔ mutants revealed that the ...
Mahmoud Waheed Abdelmonsef - - 2013
This study aimed to determine whether serum levels of nitric oxide metabolites (nitrates and nitrites) correlate with renal dysfunction in patients with liver cirrhosis and, moreover, to assess nitric oxide metabolite (NOx) power for predicting hepatorenal syndrome (HRS) in such patients. Among patients admitted to the Tropical Medicine Department, Ain ...
Laoutidis Zacharias G - - 2013
Akathisia is a common and distressing extrapyramidal side-effect, which usually results from the use of antipsychotic medication. Previous reviews and meta-analyses have demonstrated a lack of evidence for the effectiveness of treatment strategies, which are traditionally used against neuroleptic-induced akathisia (NIA), i.e. beta-blockers, anticholinergic agents and benzodiazepines. In the last ...
Matsubara Yasuo - - 2013
The reactivity of a rhenium complex containing an NAD(+) model ligand was examined toward photochemical formation of the corresponding NADH-like dihydro form of the complex and electrochemical CO2 reduction. The hydricity of the NADH-like complex was estimated by a thermodynamic cycle and reaction with Ph3C(+).
Sørensen G - - 2013
Anatomical structures and their distensibility vary along the length of the anal canal. The anal sphincter muscles have dynamic properties that are not well-reflected by standard manometry. Abnormal distensibility of the anal canal may be of importance in idiopathic fecal incontinence (IFI). The functional lumen imaging probe (FLIP) allows detailed ...
Winter Sebastian E - - 2013
The large intestine is host to a complex ecological community composed predominantly of obligate anaerobic bacteria belonging to the classes Bacteroidia and Clostridia. This community confers benefit through its metabolic activities and host interactions. However, a microbial imbalance (dysbiosis) characterized by a decreased abundance of Clostridia and a bloom of ...
Shafer F - - 2013
Spontaneous haemorrhage in patients with haemophilia is generally considered to occur randomly and without a predictable temporal or seasonal pattern; however, there is a lack of evidence in the literature on the effects of weather, temperature and atmosphere on bleeding episodes. This post hoc analysis of a multicentre, open-label crossover ...
Low Jingxiang - - 2013
Photocatalytic degradation of pollutants in water has received much attention due to increasing environmental problems. In this study, a visible-light-driven plasmonic silver-graphene-bismuth tungsten (Ag-G-Bi2WO6) composite photocatalyst was prepared. Firstly, the graphite oxide (GO)-Bi2WO6 composite was prepared using a hydrothermal process, followed by a chemical reduction process using ethyl glycol (EG) ...
Dhingra Sadhna - - 2013
SLE-associated tubulointerstitial injury (SLE TIN) is increasingly recognized in two forms, i.e. secondary and primary. The secondary form coexists with lupus glomerulonephritis, whereas the primary form develops against the background of no or mild glomerular or vascular involvement. Secondary SLE TIN is frequent, but its frequency and severity correlate with ...
Almasalmeh Abdulnasser - - 2013
Aquaporins (AQP) conduct small, uncharged molecules, such as water (orthodox AQPs), ammonia (aquaammoniaporins), or glycerol (aquaglyceroporins). Physiological functions of AQPs are in the osmotic volume regulation or transport of biochemical precursors and metabolic waste products. The recent identification of hydrogen peroxide (H2 O2 ) as a permeant of certain AQPs ...
Ozener Baris - - 2013
While consanguineous marriage has been shown to result in a small increase in risk of recessive Mendelian disorders among offspring, far less research has been conducted on the effects of inbreeding on complex traits. These effects, thought to result from increased developmental instability due to loss of heterozygosity, are expected ...
Louvel Hélène - - 2013
Genome analysis of over 70 Saccharomyces strains revealed the existence of five groups of genetically diverged S. cerevisiae wild-type isolates, which feature distinct genetic backgrounds and reflect the natural diversity existing among the species. The strains originated from different geographical and ecological niches (Malaysian, West African, North American, Wine/European, and ...
Smith Nicole K - - 2013
Almost half of all pregnancies in the United States are unintentional, unplanned, or mistimed. Most unplanned pregnancies result from inconsistent, incorrect, or nonuse of a contraceptive method. Diminished sexual function and pleasure may be a barrier to using hormonal contraception. This study explores sexual function and behaviors of women in ...
Zhu Guizhi - - 2013
Phthalocyanine (Pc) molecules are well-known flexible structural units for 1D nanotubes and 2D nanosheets. First-principles calculations combined with grand canonical Monte Carlo simulations are used to obtain the geometries, electronic structures, optical properties, and hydrogen-storage capacities of nanocages consisting of six Pc molecules with six Mg or Ca atoms. The ...
Mayer Philipp - - 2013
Passive sampling methods (PSMs) allow the quantification of the freely dissolved concentration (Cfree ) of an organic contaminant even in complex matrices such as sediments. Cfree is directly related to a contaminant's chemical activity, which drives spontaneous processes including diffusive uptake into benthic organisms and exchange with the overlying water ...
Djukanovic N - - 2013
Premature discontinuation of clopidogrel in patients undergoing percutaneous coronary intervention is a significant risk factor for thrombotic adverse outcomes. However, recent studies indicate that even discontinuation of long-term use of clopidogrel may be associated with multiple adverse outcomes, that is, rebound phenomenon whose mechanism is not definitely clear. The aim ...
Castillo-Castrejon Marisol - - 2013
Human parturition is associated with an intrauterine pro-inflammatory environment in the choriodecidua. Evidence that some mediators of this signaling cascade also elicit responses leading to labor prompted us to characterize the cellular sources of these mediators in the human choriodecidua. Leukocyte-enriched preparations from human choriodecidua (ChL) and intervillous placental blood ...
Afrasiabi Garekani Hadi - - 2013
Abstract This study evaluated ethylcellulose (EC) in two forms in preparation of sustained release theophylline microparticles using spray drying. Spray dried (SD) samples at different drug:polymer ratios were prepared using Surelease (SDaq) or organic solutions of ethylcellulose (SDor). Properties of particles (yield, particle morphology, size distribution and release profiles) were ...
Vilaça Rita - - 2013
The Niemann-Pick type C is a rare metabolic disease with a severe neurodegenerative phenotype characterized by an accumulation of high amounts of lipids (cholesterol and sphingolipids) in the late endosomal/lysosomal network. It is caused by loss-of-function point mutations in either NPC1 or NPC2, which seem to mediate proper intracellular lipid ...
Ushakov Dmitry B - - 2013
Primary and secondary amines can be rapidly and quantitatively oxidized to the corresponding imines by singlet oxygen. This reactive form of oxygen was produced using a variable-temperature continuous-flow LED-photoreactor with a catalytic amount of tetraphenylporphyrin as the sensitizer. α-Aminonitriles were obtained in good to excellent yields when trimethylsilyl cyanide served ...
Parise Amelia - - 2013
Abstract The aim of this study was to incorporate a new naphthalenediimide derivative (AN169) with a promising anticancer activity into pegylated liposomes to an extent that allows its in vitro and in vivo testing without use of toxic solvent. AN169-loaded liposomes were prepared using the thin-film hydration method and characterized ...
Itagaki Munenori - - 2013
Abstract Objectives. Ulcerative colitis (UC) is a chronic, relapsing and remitting intestinal inflammatory disorder. Zinc is known to be efficacious for the repair of damaged tissue and has been shown to protect against gastric ulceration. This study focused on Polaprezinc (PZ), N-(3-aminopropionyl)-L-histidinato zinc, which accelerates ulcer healing through actions such ...
Colman D R - - 2013
Hydrothermal springs harbor unique microbial communities that have provided insight into the early evolution of life, expanded known microbial diversity, and documented a deep Earth biosphere. Mesothermal (cool but above ambient temperature) continental springs, however, have largely been ignored although they may also harbor unique populations of micro-organisms influenced by ...
Stember Doron S - - 2013
Inflatable penile prosthesis (IPP) surgery is a successful therapeutic option for men with erectile dysfunction. Traditional placement of the reservoir in the retropubic space of Retzius is associated with the rare occurrence of significant complications including bladder, bowel, and vascular injury. An alternative site, posterior to the abdominal wall musculature, ...
Giselbrecht Stefan - - 2013
The term "cyborg" refers to a cybernetic organism, which characterizes the chimera of a living organism and a machine. Owing to the widespread application of intracorporeal medical devices, cyborgs are no longer exclusively a subject of science fiction novels, but technically they already exist in our society. In this review, ...
Kokubo Rinko - - 2013
Object Spinal subdural hematomas (SDHs) are rare and some are concomitant with intracranial SDH. Their pathogenesis and etiology remain to be elucidated although their migration from the intracranial space has been suggested. The authors postulated that if migration plays a major role, patients with intracranial SDH may harbor asymptomatic lumbar ...
Sharma Mayur - - 2013
Object The aim of this study was to analyze the incidence of adverse outcomes and inpatient mortality following resection of intramedullary spinal cord tumors by using the US Nationwide Inpatient Sample (NIS) database. The overall complication rate, length of the hospital stay, and the total cost of hospitalization were also ...
Manjila Sunil - - 2013
The authors present a case of traumatic, complete, high cervical spine injury in a patient with gradual worsening deformity and neck pain while in rigid cervical collar immobilization, ultimately resulting in coronal-plane spondyloptosis. Due to the extent of lateral displacement of the spinal elements, preoperative evaluation included catheter angiography, which ...
Gonzalez-Blohm Sabrina A - - 2013
Object In this paper the authors evaluate through in vitro biomechanical testing the performance of an interspinous fusion device as a stand-alone device, after lumbar decompression surgery, and as supplemental fixation to expandable cages in a posterior lumbar interbody fusion (PLIF) construct. Methods Nine L3-4 human cadaveric spines were biomechanically ...
Singh Satyakam - - 2013
Multidrug resistance caused by ATP binding cassette transporter P-glycoprotein (P-gp) through extrusion of anticancer drugs from the cells is a major cause of failure in cancer chemotherapy. Previously, selenazole-containing cyclic peptides were reported as P-gp inhibitors and were also used for co-crystallization with mouse P-gp, which has 87 % homology to ...
Connaughton J - - 2013
Many people with mental health disorders experience fatigue, pain and poor sleep. In other patient groups, physical exercise has been shown to have positive effects on these symptoms. It is unknown whether day-to-day physical activity (not necessarily exercise) affects sleep quality or severity of pain or fatigue in those with ...
Nurden Alan T - - 2013
Genetic defects of platelets constitute rare diseases that include bleeding syndromes of autosomal dominant, recessive or X-linked inheritance. They affect platelet production, resulting in a low circulating platelet count and changes in platelet morphology, platelet function, or a combination of both with altered megakaryopoiesis and a defective platelet response. As ...
Goodman Jarid - - 2013
Extensive evidence indicates that mammalian memory is organized into multiple brains systems, including a 'cognitive' memory system that depends on the hippocampus and a stimulus-response 'habit' memory system that depends on the dorsolateral striatum. Dorsal striatal-dependent habit memory may in part influence the development and expression of some human psychopathologies, ...
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