Search Results
Results 201 - 250 of 2229
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DU Li-Qun - - 2013
Glaucoma filtering surgery (GFS) is the most common procedure performed in the treatment of glaucoma. Although antiscarring agents help prevent postsurgical scarring and improve glaucoma surgical outcomes, they may be associated with an increased incidence of severe and potentially blinding complications. Poly(DL-lactide-co-glycolide) (PDLLA/GA) is a bioresorbable polymer, which can be ...
Li Hong - - 2013
To assess the cartilage status of the knee joints using magnetic resonance imaging at least 2 years after anterior cruciate ligament reconstruction (ACLR) in young adult men. Thirty young male patients with unilateral ACLR and 15 age-matched and body mass index-matched healthy men (controls) participated in this study. All participants ...
Lee Su Jeong - - 2013
Ultraviolet B (UVB) radiation induces the production of reactive oxygen species (ROS) that promote apoptotic cell death. We showed that cytosolic NADP+-dependent isocitrate dehydrogenase (IDPc) plays essential role in the control of cellular redox balance and defense against oxidative damage by supplying NADPH for antioxidant systems. In this study, we ...
Beit Philipp P Research fellow, Department for Orthodontics and Pediatric Dentistry, Center of Dental Medicine, University of Zurich, Zurich, - - 2013
The aim of this study was to examine the agreement of skeletal age assessment based on hand-wrist radiographs with cephalogram-based cervical vertebrae evaluation. To circumvent bias and loss of information from staging, a quantitative approach was applied to determine morphologic changes. We analyzed 730 sets of radiographs (cephalogram and hand-wrist) ...
Vlassara Helen - - 2013
This review presents insights from studies of advanced glycation end products (AGEs) in humans and mice. Although the emphasis is on the effects of exogenous AGEs and the suppression of specific host defense mechanisms, AGEs are also formed intracellularly, where they may contribute to several normal intracellular functions. It is ...
Ozturk Burak Yagmur - - 2013
To prospectively evaluate the return-to-sports rates after arthroscopic anterior stabilization in patients aged younger than 25 years. Fifty-eight patients underwent arthroscopic capsulolabral repair for isolated anterior instability. The mean age at the time of surgery was 19.5 years (range, 12 to 24 years). At a mean follow-up of 27 months ...
Jiang Li-Hong - - 2013
Graves' ophthalmopathy/orbitopathy (GO) patients often suffer ocular surface damages and tear fluid proteins play a significant role in maintaining healthy ocular surfaces, while changes in tear protein components reflect the changes ocular surface abnormalities. In this study proteomics techniques were used to investigate tear protein compositions in GO patients. We ...
Xue Cheng - - 2013
IgA nephropathy (IgAN) is the most common primary glomerular disease. Transforming growth factor β1 (TGFβ1) plays an important role in pathogenesis of IgAN. Associations between the polymorphisms of TGFβ1 gene and the risk of IgAN remained inconsistent. A meta-analysis was conducted to investigate the association between polymorphisms in the TGFβ1 ...
Han Wei - - 2013
Polypyrimidine tract-binding protein 1 (PTBP1) and its brain-specific homologue, PTBP2, are associated with pre-mRNAs and influence pre-mRNA processing, as well as mRNA metabolism and transport. They play important roles in neural differentiation and glioma development. In our study, we detected the expression of the two proteins in glioma cells and ...
de Jong Lex D - - 2013
Does static stretch positioning combined with simultaneous neuromuscular electrical stimulation (NMES) in the subacute phase after stroke have beneficial effects on basic arm body functions and activities? Multicentre randomised trial with concealed allocation, assessor blinding, and intention-to-treat analysis. Forty-six people in the subacute phase after stroke with severe arm motor ...
Yang Jun - - 2013
Large and giant medial sphenoid wing meningiomas that are located deeply in the skull base where they are closely bounded by cavernous sinus, optic nerve, and internal carotid artery make the gross resection hard to achieve. Also, this kind of meningiomas is often accompanied by a series of severe complications. ...
Everett Bethany G - - 2013
Researchers investigating the relationship between education and mortality in industrialized countries have consistently shown that higher levels of education are associated with decreased mortality risk. The shape of the education-mortality relationship and how it varies by demographic group have been examined less frequently. Using the U.S. National Health Interview Survey-Linked ...
Wang Chao-Hong - - 2013
Pulmonary hypertension (PH) is a set of pathophysiological syndromes characterized by increased pulmonary artery pressure and pulmonary vascular resistance, resulting in increased right ventricular afterload. The left and right ventricles interact through hemodynamics. What impact will PH have on synchronization and function of the left ventricle (LV)? The aim of ...
Gleason Jonathan L - - 2013
Female pelvic medicine and reconstructive surgery (FPMRS) is a rapidly expanding surgical specialty that focuses on the evaluation and treatment of pelvic floor disorders in women. Evaluation and treatment of several pelvic floor disorders can be accomplished with office-based procedures, yielding significant advantages to the patient, physician, and health system. ...
Scott Richard T RT - - 2013
Medicine and aviation have a striking number of similarities. Both are led by highly-trained individuals performing complex tasks that are critical to outcomes. They also integrate the efforts of other professionals to assure that the flight, procedures, or processes are completed successfully. Also in common, is the potential for errors ...
Lee Jisun - - 2013
Corn silk (CS) has long been consumed as a traditional herb in Korea. Effects of maysin, a major flavonoid of CS, on macrophage activation were evaluated using the murine macrophage RAW 264.7 cells. Maysin was isolated from CS by methanol extraction and preparative C18 reverse phase column chromatography. Maysin was ...
Allen Rebecca H - - 2013
As minor gynecologic procedures move from the operating room to the office, providers need to ensure that patients are comfortable and that procedures are performed safely. Although local anesthesia is commonly used for gynecologic procedures, a multimodal approach may be more effective. If necessary, sedation can be safely provided in ...
Ludlow John B JB Professor, Department of Diagnostic Sciences, School of Dentistry, University of North Carolina, Chapel Hill, NC. Electronic address: - - 2013
The increasing use of cone-beam computed tomography in orthodontics has been coupled with heightened concern about the long-term risks of x-ray exposure in orthodontic populations. An industry response to this has been to offer low-exposure alternative scanning options in newer cone-beam computed tomography models. Effective doses resulting from various combinations ...
Feng Juan - - 2013
Accurate evaluation of coronary artery, aortic valve annulus diameter (AVAD), and cardiac function in patients with aortic valve disease is of great significance for surgical strategy. In this study, we explored the preoperative evaluation of low-dose sequence (MinDose sequence) scan of dual-source CT (DSCT) for those patients. Forty patients suspected ...
Al-Bitar Zaid B - - 2013
The aims of this study were to investigate the experience of bullying in a representative sample of Jordanian schoolchildren in Amman, to look at its effect on school attendance and perception of academic performance, and to look at the contribution of general physical and dentofacial features to this phenomenon. This ...
Shi Junjun - - 2013
To evaluate the effect of poly(lactic-co-glycolic acid) (PLGA) nanoparticles delivering pDC316-BMP4-EGFP plasmid into rabbit adipose-derived stem cells (ADSCs) in vitro and chondrogenesis of the bone morphogenetic protein 4 (BMP-4)-transfected ADSCs seeded onto poly(L-lactic-co-glycolic acid) (PLLGA) scaffold in a rabbit model. Cell viability and transfection efficiency of PLGA nanoparticles were measured by Cell ...
Li Xiu-Juan - - 2013
Myopia is a common disorder and the incidence has increased yearly, but its pathogenesis remains unclear. The aim of this study was to investigate the possible role of hepatocyte growth factor (HGF) and its receptor c-Met in the development of lens-induced myopia in guinea pigs. Sixty one-week-old guinea pigs were ...
Kuranuki Sachi - - 2013
Objective: To develop a minimally invasive interstitial fluid extraction technology (MIET) to monitor postprandial glucose area under the curve (AUC) without blood sampling, we evaluated the accuracy of glucose AUC measured by MIET and compared with that by blood sampling after food intake. Methods: Interstitial fluid glucose AUC (IG-AUC) following ...
Kwon Ji-Sun - - 2013
Speed of sound (SOS) value is an indicator of bone mineral density (BMD). Previous genome-wide association (GWA) studies have identified numbers of genes whose variations may affect BMD levels. However, their biological implications have been elusive. We re-analyzed the GWA study dataset for the SOS values in skeletal sites of ...
Nelson Erik R ER Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27710, - - 2013
Hypercholesterolemia is a risk factor for estrogen receptor (ER)-positive breast cancers and is associated with a decreased response of tumors to endocrine therapies. Here, we show that 27-hydroxycholesterol (27HC), a primary metabolite of cholesterol and an ER and liver X receptor (LXR) ligand, increases ER-dependent growth and LXR-dependent metastasis in ...
Gregory Thomas - - 2013
Background and purpose It is difficult to evaluate glenoid component periprosthetic radiolucencies in total shoulder arthroplasties (TSAs) using plain radiographs. This study was performed to evaluate whether computed tomography (CT) using a specific patient position in the CT scanner provides a better method for assessing radiolucencies in TSA. Methods Following ...
Altun Z - - 2013
Cisplatin is an anti-neoplastic agent treatment with which causes many side effects including ototoxicity. The aim of this study was to investigate whether acetyl-l-carnitine would have protective effects on cisplatin-induced ototoxicity in vitro, and if present, to reveal roles of apoptotic gene expressions and pro-inflammatory cytokines. House Ear Institute-Organ of ...
Froeding Ligita Paskeviciute - - 2013
Radical vaginal trachelectomy (RVT) offers low complication rate, good survival, and possibility for future childbearing for young women with early stage cervical cancer. However, the literature on quality of life (QOL) and sexual functioning in patients undergoing RVT is scarce. The aims of this study were to prospectively assess sexual ...
Koppel Jonathan - - 2013
The reminiscence bump refers to the disproportionate number of individualÅ› autobiographical memories which date from young adulthood. A similar bump is found in cultural life scripts: When people are asked to nominate and date major transitional events in a typical life course in their culture, a disproportionate number of the ...
Ha Yonghwang - - 2013
α-Synuclein oligomers can induce neurotoxicity and are implicated in Parkinson's disease etiology and disease progression. Many studies have reported α-synuclein oligomerization by dopamine (DA) and transition metal ions, but few studies provide insight into joint influences of DA and Cu(2+) . In this study, DA and Cu(2+) were coadministered aerobically ...
Strand H - - 2013
To compare attitudes towards Kangaroo Mother Care (KMC) among staff in two high-tech neonatal intensive care units, which provided parents with different opportunities to get involved in their infants' care. Questionnaires were completed by healthcare staff in Unit A, which provided parents with unrestricted access so that they could provide ...
Djukanovic N - - 2013
Premature discontinuation of clopidogrel in patients undergoing percutaneous coronary intervention is a significant risk factor for thrombotic adverse outcomes. However, recent studies indicate that even discontinuation of long-term use of clopidogrel may be associated with multiple adverse outcomes, that is, rebound phenomenon whose mechanism is not definitely clear. The aim ...
Li Lingyao - - 2013
pH-Responsive polymers have great potential in biomedical applications, including the selective delivery of preloaded drugs to tissues with low pH values. These polymers usually contain acid-labile linkages such as esters and acetals/ketals. However, these linkages are only mildly pH-responsive with relatively long half-lives (t1/2 ). Orthoester linkages are more acid-labile, ...
Zhang Dehui D Department of Chemistry, Washington State University, Pullman, WA 99164 - - 2014
Protein S-sulfhydration (forming -S-SH adducts from cysteine residues) is a newly defined oxidative posttranslational modification and plays an important role in H2 S-mediated signaling pathways. In this study we report the first selective, "tag-switch" method which can directly label protein S-sulfhydrated residues by forming stable thioether conjugates. Furthermore we demonstrate ...
Nota Laura - - 2013
This study examines the importance of work in life of people with disability and then focuses on employer attitudes towards these people. In the light of Stone and Colella's model, the study examines the employer attitudes and the role of variables such as type of disability, employer experience in the ...
Wang Xia - - 2013
A novel multifunctional nanotheranostic agent with targeting, redox-responsive ultrasound imaging and ultrasound imaging-guided high-intensity focused ultrasound (HIFU) therapy (MSNC-PEG-HASS -PFH, abbreviated as MPHSS -PFH) capabilities is developed. The redox-responsive guest molecule release and ultrasound imaging functions can be both integrated in such a "smart" theranostic agent, which is accomplished by the redox-triggered ...
Steinhilber Dirk - - 2013
pH-Cleavable cell-laden microgels with excellent long-term viabilities were fabricated by combining bioorthogonal strain-promoted azide-alkyne cycloaddition (SPAAC) and droplet-based microfluidics. Poly(ethylene glycol)dicyclooctyne and dendritic poly(glycerol azide) served as bioinert hydrogel precursors. Azide conjugation was performed using different substituted acid-labile benzacetal linkers that allowed precise control of the microgel degradation kinetics in ...
Pocoski J - - 2013
There is conflicting evidence in the literature on whether individuals with haemophilia in the USA have greater, reduced, or similar risks for cardiovascular disease as the general population. This study evaluated the prevalence of cardiovascular comorbidities among USA males with haemophilia A, relative to an unaffected general male population with ...
Al-Hussein Anas - - 2013
Abstract The objective of this study was to investigate both the cryoprotective and lyoprotective effects of the polymer hydroxyethyl cellulose (HEC) on the model protein lactate dehydrogenase (LDH) during freeze thawing and freeze drying cycles. The effect of annealing on both protein stability and the physical state of HEC was ...
Gonzalez-Blohm Sabrina A - - 2013
Object In this paper the authors evaluate through in vitro biomechanical testing the performance of an interspinous fusion device as a stand-alone device, after lumbar decompression surgery, and as supplemental fixation to expandable cages in a posterior lumbar interbody fusion (PLIF) construct. Methods Nine L3-4 human cadaveric spines were biomechanically ...
Brown T N - - 2013
A group contribution-based quantitative structure-property relationship (QSPR) for the hexadecane-air equilibrium partition coefficients (L) of organic chemicals is developed using the iterative fragment selection (IFS) approach. This new QSPR includes in its training and external validation data sets L values for a large number of structurally complex chemicals measured by ...
Jay C M - - 2013
PDX1 (pancreatic and duodenal homeobox 1) is overexpressed in pancreatic cancer, and its reduction results in tumor regression. Bi-functional pbi-shRNA PDX1 nanoparticle (OFHIRNA-PDX1) utilizes the endogenous micro-RNA biogenesis pathway to effect cleavage- and non-cleavage-dependent degradation of PDX1 mRNA. We have shown that OFHIRNA-PDX1 reduces pancreatic tumor volume in xenograft models. ...
Lerner Nataly - - 2013
Background: The ADA 2010 guidelines added HbA1c ≥ 6.5% as a criterion for diagnosing diabetes mellitus type 2. Objective: To evaluate the HbA1c test in predicting type 2 diabetes in a high risk population. Methods: A community-based historic cohort study was conducted including 10 201 patients, who had not been ...
Varade Dharmesh - - 2013
We report a novel simple one-pot strategy for fabricating pure and highly planar silver (Ag) crystal belts. Unique single-crystal Ag belts (high width-to-thickness ratio ∼50) were successfully synthesized in high yield (80 wt%) by reducing AgNO3 using N,N,N',N'-tetramethylethylenediamine (TEMED) as a reducing and a structure-determining agent in the presence of ...
Xu Jin-Shi - - 2013
Revivals of quantum correlations in composite open quantum systems are a useful dynamical feature against detrimental effects of the environment. Their occurrence is attributed to flows of quantum information back and forth from systems to quantum environments. However, revivals also show up in models where the environment is classical, thus ...
Zuo Weiwei - - 2013
A rational approach is needed to design hydrogenation catalysts that make use of Earth-abundant elements to replace the rare elements such as ruthenium, rhodium, and palladium that are traditionally used. Here, we validate a prior mechanistic hypothesis that partially saturated amine(imine)diphosphine ligands (P-NH-N-P) activate iron to catalyze the asymmetric reduction ...
Stovall Daniel B - - 2013
SOX7 belongs to the SOX (SRY-related HMG-box) family of transcription factors that have been shown to regulate multiple biological processes, such as hematopoiesis, vasculogenesis and cardiogenesis during embryonic development. Recent studies indicate that several SOX family members play important roles in tumorigenesis. In this review, we introduce SOX7 gene and ...
Silva Katiane L - - 2013
The frequent comorbidity between attention-deficit hyperactivity disorder (ADHD) and bipolar disorder (BD) represents a challenge for disentangling specific impairments of each disorder in adulthood. Their functional impairments seem to be mediated by executive function deficits. However, little is known about the extent to which each executive function deficit might be ...
Chen Yingzhi - - 2013
Organic nanostructures in terms of porphyrin building blocks have shown great potential in visible-light photocatalytic applications because of their optical, electrical, and catalytic properties. Graphenes are known to provide a high-quality two-dimensional (2D) support for inorganic semiconductor nanostructures to increase the adsorption capability of the photocatalysts and an electron-transfer medium ...
Almasalmeh Abdulnasser - - 2013
Aquaporins (AQP) conduct small, uncharged molecules, such as water (orthodox AQPs), ammonia (aquaammoniaporins), or glycerol (aquaglyceroporins). Physiological functions of AQPs are in the osmotic volume regulation or transport of biochemical precursors and metabolic waste products. The recent identification of hydrogen peroxide (H2 O2 ) as a permeant of certain AQPs ...
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