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Calhoun Karen H - - 2014
Measuring fractional exhaled nitric oxide (FeNO) is a relatively new option for assessing allergic inflammation in the lungs. Clinical management of asthma is challenging, and measuring exhaled nitric oxide can provide another type of data to assist in meeting this challenge. FeNO is easy to perform, and the equipment is ...
McCarty Justin C - - 2014
Asthma has many triggers including rhinosinusitis; allergy; irritants; medications (aspirin in aspirin-exacerbated respiratory disease); and obesity. Paradoxic vocal fold dysfunction mimics asthma and may be present along with asthma. This article reviews each of these triggers, outlining methods of recognizing the trigger and then its management. In many patients more ...
Boise Elizabeth - - 2014
In this article asthma assessment and patient education protocol for the Oto-Allergy Clinic at Wexner Medical Center at The Ohio State University Department of Otolaryngology, Division of Sinus and Allergy, are shared.
Okeley Nicole M - - 2014
The concept of using monoclonal antibodies for delivering drugs to cancer cells has been explored for decades, with early work surrounding nonspecific targets and drugs with low potencies. These studies underscored the importance of critical parameters, such as antigen and tumor target selection, linker stability, drug potency, pharmacokinetics, and conjugation ...
Pauly Daniel F - - 2014
Acute decompensated heart failure may occur de novo, but it most often occurs as an exacerbation of underlying chronic heart failure. Hospitalization for heart failure is usually a harbinger of a chronic disease that will require long-term, ongoing medical management. Leaders in the field generally agree that repeated inpatient admissions ...
Ansell Stephen M - - 2014
The goal of therapy for patients with advanced-stage Hodgkin lymphoma is to ensure that as many patients as possible are healthy and free of disease decades after completing treatment. To achieve this, the treating physician needs to select the most effective therapeutic regimen, but also needs to choose a treatment ...
Diefenbach Catherine - - 2014
Although most patients with Hodgkin lymphoma (HL) are cured with primary therapy, patients with primary refractory disease or relapse after initial treatment have poor outcomes and represent an unmet medical need. Recent advances in unraveling the biology of HL have yielded a plethora of novel targeted therapies. This review provides ...
Hertzberg Mark - - 2014
For relapsed-refractory Hodgkin Lymphoma, standard therapy consists of salvage chemotherapy followed by autologous stem cell transplantation. Adverse risk factors at relapse include response duration less than 12 months, advanced stage, extranodal disease, "B" symptoms and anemia. There is no obvious superior salvage regimen although maintaining dose-intensity is important for optimal ...
Mechtler Laszlo L - - 2014
This article focuses on advancements in neuroimaging techniques, compares the advantages of each of the modalities in the evaluation of mild traumatic brain injury, and discusses their contribution to our understanding of the pathophysiology as it relates to prognosis. Advanced neuroimaging techniques discussed include anatomic/structural imaging techniques, such as diffusion ...
Capone Patrick M - - 2014
This article provides an imaging overview of several of the common central nervous system (CNS) infections. Neurologic clinicians who provide acute care for patients should be familiar with the range of imaging findings for patients with acute neurologic infections, including knowledge of the appropriate study and the best protocol and ...
Nandigam Kaveer - - 2014
An in-depth knowledge of the imaging characteristics of the common neurocutaneous diseases (NCD) described in this article will help neurologists understand the screening imaging modalities in these patients. The future of neuroimaging is geared towards developing and refining magnetic resonance imaging (MRI) sequences. The detection of tumors in NCD has ...
Herman Andrea - - 2014
Sjögren's syndrome is a chronic systemic autoimmune disease that can affect any organ system in the body. The most common symptoms are dryness of the mouth and eyes resulting from chronic inflammation and a progressive loss of secretory function. As with most individuals managing a chronic condition, patients with Sjögren's ...
Klarich Julie - - 2014
This article reviews occupational therapy treatment and physical therapy treatment during preprosthetic training for upper and lower extremity amputees. Review of preoperative intervention, preparing the residual limb for the prosthesis, instruction in techniques, and adaptive equipment for activities of daily living, as well as suggestions for return to vocational and ...
Kistenberg Robert S - - 2014
New technology and materials have advanced prosthetic designs to enable people who rely on artificial limbs to achieve feats never dreamed before. However, the latest and the greatest technology is not appropriate for everyone. The aim of this article is to present contemporary options that are available for people who ...
Passero Thomas - - 2014
Limb deficiency has a significant impact on the involved person, with upper limb absence presenting a materially different set of issues than lower limb absence. The primary objectives in fitting a patient with a prosthesis are to enhance their independence in performing daily activities, and to improve their quality of ...
Pirolo Joseph M - - 2014
Ulnar-sided wrist pain is a common cause of upper-extremity disability, which has long been thought of as a diagnostic and therapeutic dilemma because of the overlapping anatomy and complex differential diagnosis. Common sources of ulnar-sided pain include pathology of the triangular fibrocartilage complex, ulnocarpal impaction syndrome, lunotriquetral ligament tears, and ...
Risseeuw F F Department of Cardiac Surgery, Antwerp University Hospital, Wilrijkstraat 10, 2650, Edegem, Belgium, - - 2014
The aim of this systematic review is to gain insight into the published experience on percutaneous closure of a post-infarction ventricular septal rupture (VSR). Relevant literature was obtained by MeSH-term searches in the online search-engine PubMed. Articles published in the last 10 years were included. Further filtering was done by using ...
Nijenhuis V J VJ Department of Cardiology, St. Antonius Hospital, Koekoekslaan 1, 3435, Nieuwegein, the Netherlands, - - 2014
To assess current antithrombotic treatment strategies in the Netherlands in patients undergoing transcatheter aortic valve implantation (TAVI). For every Dutch hospital performing TAVI (n = 14) an interventional cardiologist experienced in performing TAVI was interviewed concerning heparin, aspirin, thienopyridine and oral anticoagulation treatment in patients undergoing TAVI. The response rate was 100 %. ...
Bidra Avinash S - - 2014
Evidence-based dentistry is rapidly emerging to become an integral part of patient care, dental education, and research. Prosthodontics is a unique dental specialty that encompasses art, philosophy, and science and includes reversible and irreversible treatments. It not only affords good applicability of many principles of evidence-based dentistry but also poses ...
Wiens Jonathan P - - 2014
Occlusion is the foundation for clinical success in fixed, removable, and implant prosthodontic treatment. Understanding those principles is critical when restoring a patient's occlusion. Many philosophies, devices, and theories of occlusion have evolved based on anecdotal clinical observations and applied geometric perceptions. The literature has reported these classic and contemporary ...
Baba Nadim Z - - 2014
The clinical success and longevity of indirect restorations depend on the careful and accurate completion of several procedures. One of the challenging procedures is management of the gingival tissues and gingival esthetics. The goal for management of gingival tissues and gingival esthetics is to maintain the normal appearance of healthy ...
Olvera Norma - - 2014
Specific alternatives to traditional complete denture therapy have been controversial because of the uncertainties surrounding effectiveness of retention. This article addresses the importance of retention, border molding, diagnosis, and treatment planning, and the meticulous attention to detail required throughout the treatment course of these alternative modalities. Indications, advantages, and limitations ...
Partida Mary Norma - - 2014
The geriatric population (age 65 and older) is the fastest growing segment nationally and globally. The large population will continue to increase because of baby boomers that have recently turned 65 years old. Within this cohort, there is much diversity in health, socioeconomic levels, education, and health beliefs. There is a ...
Zandparsa Roya - - 2014
Navigation technology is applied successfully in oral and maxillofacial surgery. Laser beams are used for caries removal. With nanodentistry, it is possible to maintain comprehensive oral health care. Nanorobots induce oral analgesia, desensitize teeth, and manipulate the tissue. They can also be used for preventive, restorative, and curative procedures. Strategies ...
Zandparsa Roya - - 2014
Bioceramics have been adopted in dental restorations for implants, bridges, inlays, onlays, and all-ceramic crowns. Dental bioceramics include glass ceramics, reinforced porcelains, zirconias, aluminas, fiber-reinforced ceramic composites, and multilayered ceramic structures. The process of additive manufacturing is ideally suited to dentistry. Models are designed using data from a computed tomography ...
Barewal Reva Malhotra - - 2014
Dentists are becoming increasingly aware of the importance of the detection and management of obstructive sleep apnea. The anatomic and neuromuscular risk factors in the pathogenesis of obstructive sleep apnea are reviewed with particular emphasis on oral findings. Mandibular repositioning appliances hold an important role in the treatment of this ...
De Kok Ingeborg J - - 2014
The pivotal point in treatment planning for dental implants occurs when the location of bone is viewed radiographically in the context of the planned prosthesis. Radiographic planning for dental implant therapy should be used only after a review of the patient's systemic health, imaging history, oral health, and local oral ...
Bryington Matthew - - 2014
Dental implants are an indispensible tool for the restoration of missing teeth. Their use has elevated the practice of dentistry by improving both our technical ability to rehabilitate patients and general quality of life. To routinely achieve the associated high expectations, diligent attention to details must be observed and addressed ...
Thalji Ghadeer - - 2014
Implant-supported dental restorations can be screw-retained, cement-retained, or a combination of both, whereby a metal superstructure is screwed to the implants and crowns are individually cemented to the metal frame. Each treatment modality has advantages and disadvantages. The use of computer-aided design/computer-assisted manufacture technologies for the manufacture of implant superstructures ...
Yanase Roy T - - 2014
The development of an oral care path focuses on the identification of the early indicators of disease. Once the risks have been identified and diagnosed, the proper therapies can be selected and prescribed. The experienced practitioner must meld clinical experience and observation with evidence-based scientific dentistry and information on the ...
Lang Lisa A - - 2014
A critically appraised topic (CAT) review is presented about the use of computer-aided design (CAD)/computer-aided machining (CAM) removable partial denture (RPD) frameworks. A systematic search of the literature supporting CAD/CAM RPD systems revealed no randomized clinical trials, hence the CAT review was performed. A PubMed search yielded 9 articles meeting ...
Bohnenkamp David M - - 2014
This article provides a review of the traditional clinical concepts for the design and fabrication of removable partial dentures (RPDs). Although classic theories and rules for RPD designs have been presented and should be followed, excellent clinical care for partially edentulous patients may also be achieved with computer-aided design/computer-aided manufacturing ...
Tanck Esther E Orthopaedic Research Laboratory, Radboud university medical center, PO Box 9101, 6500 HB, Nijmegen, the Netherlands, - - 2014
Many students in Biomedical Sciences have difficulty understanding biomechanics. In a second-year course, biomechanics is taught in the first week and examined at the end of the fourth week. Knowledge is retained longer if the subject material is repeated. However, how does one encourage students to repeat the subject matter? ...
Abu-Zaid Ahmed A College of Medicine, Alfaisal University, PO Box 50927, Riyadh, 11533, Saudi Arabia, - - 2014
There is a rapidly increasing movement towards integrating scientific research training into undergraduate medical education. The aim of this study was to explore the perceived attitudes of female second-year undergraduate medical students towards research at the College of Medicine, Alfaisal University, Saudi Arabia, as well as to explore if any ...
Garcia-Soto E - - 2013
INTRODUCTION. Stroke is one of the main causes of disability. Physical activity has shown a benefit in the physical rehabilitation of these patients. However, its role improving cognitive function has not been studied by far. AIM. To review studies that evaluate the impact of physical activity on cognitive recovery after ...
Herrero-San Martin A - - 2013
INTRODUCTION. Alzheimer's disease (AD) is the most frequent degenerative dementia in our setting. In most patients the initial manifestations of the disease consist in a selective and progressive compromise of memory. Yet, it is not a homogeneous process and in some cases the mode of presentation can be atypical. The ...
Diaz-Anzaldua A - - 2013
INTRODUCTION. Autism spectrum disorders (ASD) are common and complex neuropsychiatric disorders in which multiple factors may contribute to the phenotype. AIM. To review current knowledge about possible risk factors for ASD. DEVELOPMENT. Medline, OMIM and Ensembl databases were searched for possible risk factors, disease and gene information. CONCLUSIONS. There is ...
Munoz I - - 2013
INTRODUCTION. Psychiatric comorbidity is frequent in cases of migraine and research has focused more on that related to affective disorders and anxiety than to personality traits. AIMS. To study the presence of personality traits in persons with migraine and how they are related with the presence of chronic migraine or ...
Ramon-Carbajo C - - 2013
We review the development of rizatriptan, one of the seven 5-HT1B/1D agonists available for the symptomatic treatment of migraine, emphasizing the most relevant contributions carried out from our country. Rizatriptan has shown the quickest onset of action, both in controlled studies and in the different metaanalyses, which translates in high ...
Verbrugge Frederik H - - 2013
In ambulatory patients with heart failure (HF) and reduced ejection fraction (rEF), renin-angiotensin system (RAS) and β-blockers at guideline-recommended target dose reduce all-cause mortality and readmissions. Benefits in HF with preserved ejection fraction (pEF), as well as uptitration after a hospitalization, remain uncertain. This study assesses the impact of RAS- ...
Sharma Rishi R Center for Drug Discovery and Departments of Chemistry and Chemical Biology and Pharmaceutical Sciences, Northeastern University , Boston, Massachusetts 02115, United - - 2013
We report an approach for obtaining novel cannabinoid analogues with controllable deactivation and improved druggability. Our design involves the incorporation of a metabolically labile ester group at the 2'-position on a series of (-)-Δ(8)-THC analogues. We have sought to introduce benzylic substituents α to the ester group which affect the ...
Walder Joan F - - 2013
Esthetic considerations play an increasingly important role in patient care, and clinicians need a methodology that includes imaging techniques to capture the dynamic nature of the smile. Photographs of the posed smile are routinely used to guide diagnosis and treatment, but there is no standardized and validated method for recording ...
Akyalcin Sercan - - 2013
The aim of this study was to assess the diagnostic accuracy and surface matching characteristics of 3-dimensional digital dental models obtained from various sources. Three sets of maxillary and mandibular digital models of 30 subjects were included in this study. Three-dimensional stereolithography model files were obtained from a 3-dimensional laser ...
Beit Philipp - - 2013
The aim of this study was to examine the agreement of skeletal age assessment based on hand-wrist radiographs with cephalogram-based cervical vertebrae evaluation. To circumvent bias and loss of information from staging, a quantitative approach was applied to determine morphologic changes. We analyzed 730 sets of radiographs (cephalogram and hand-wrist) ...
Katyal Vandana - - 2013
The association between pediatric sleep-disordered breathing caused by upper airway obstruction and craniofacial morphology is poorly understood and contradictory. The aims of this study were to evaluate the prevalence of children at risk for sleep-disordered breathing, as identified in an orthodontic setting by validated screening questionnaires, and to examine associations ...
Al-Bitar Zaid B - - 2013
The aims of this study were to investigate the experience of bullying in a representative sample of Jordanian schoolchildren in Amman, to look at its effect on school attendance and perception of academic performance, and to look at the contribution of general physical and dentofacial features to this phenomenon. This ...
Keser Elif I - - 2013
Piezocision-assisted orthodontic treatment is an innovative, minimally invasive surgical technique designed to help achieve rapid orthodontic tooth movement. Microsurgical interproximal openings are made in the buccal gingivae to let the piezoelectric knife create the bone injury that will lead to transient demineralization and subsequent accelerated tooth movement. When this procedure ...
Standerwick Richard G - - 2013
Erythropoietic protoporphyria (EPP) is an inherited blood disorder in which formation of the heme group of hemoglobin is defective. Specifically, a deficiency of the enzyme ferrochelatase leads to the accumulation of protoporphyrin, resulting in often painful photosensitivity of the skin and tissues. The prevalence of EPP is estimated at 1:75,000 ...
Araújo Eustáquio A - - 2013
This clinical article reports a technique, apicotomy, for managing dilacerated or ankylosed canines. The records of 3 patients successfully treated with apicotomy are presented. Orthodontists observe clinically significant incidences of impacted maxillary canines in their daily practices. Several procedures have been described to bring an ankylosed, impacted tooth into occlusion. ...
Akyalcin Sercan - - 2013
Impression-free techniques might eliminate the potential shortcomings of digital dental models. Chairside scanners offer the advantage of obtaining digital dental models directly from the patient without the need for dental impressions. The aim of this study was to evaluate the accuracy of 3-dimensional digital models acquired from a chairside intraoral ...
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